Gene 13374 (Tetrahymena)

13374

Species: Tetrahymena
Alias: TTHERM_00361590, 263, 13374, 38.m00209, PreTt13374
External Links: Tetrahymena Genome Database (TGD)
Annotation: Secondary Group: Other, Secondary Family: Ciliate_C8_Cterm, Secondary Subfamily: C2,

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C2

Sequence

Name Sequence Type Origin Length Description Download
13374.AA Protein None 617 None Fasta, JSON
13374.kin_dom Protein Kinase Domain None 218 None Fasta, JSON
13374.kin_dom2 Protein Kinase Domain None 124 None Fasta, JSON
13374.NA RNA None 1854 None Fasta, JSON

Protein domain

Protein domains of 13374.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13374.AA C2 144-369 53 1.4e-137 463.39 In-house 1-245 (245) Show / Hide 
Range on Protein: 144-369
Range on HMM: 1-245/245
Sequence Identity: 53% (130 aa)

GAFSFVLKATNQKTGQIIALKVTECDDNDINGMKQVEEEYRLLRQFSNCKYIVQVFNCFFLTEEESSDDDCSNDDEEEG----KNEKKEKNLFFVVEQEF
|||..||||.|.|.....|||..||..||||||..|..||...||..|..||..|.|.|.||.....|.|..||.||..    |..|.||..|.|.||||
GAFGLVLKAFNKKQNRHVALKIQECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQEF

CQTNLENFFTQCRLKKSYPCQQQKEVMAIQMLDSVAYLHRFDLLHRDIKPSNFLLSLDEKEIPTVKICD----------LSFASALKNNKSRITVSKIKG
||.||...|..|| ..||||||.|..|||||.||..||||||..||||||||||...|...|||.|.||          ..|||.||.|||||..||.|.
CQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKKCDFDFASKLKYNKSRIHFSKFKW

TQAY----FAPEVEKGVYKKGSDVFS-LGLVLLELDNMSNFNFND
||.|    |||||....||| ||.|| .|.||||||||. .....
TQQYYQHIFAPEVYQNIYKKNSDLFSTVGYVLLELDNMQQYTICC
Kinase 13374.AA Ciliate-C8 144-356 44 2.4e-105 356.27 In-house 1-238 (238) Show / Hide 
Range on Protein: 144-356
Range on HMM: 1-238/238
Sequence Identity: 44% (107 aa)

GAFSFVLKATNQKTGQIIALKVTEC-DDNDINGMKQVEEEYRLLRQFSNCKYIVQVFNCFFLTEEESSDDDCSNDDEEEGKNE-KKEKNLFFVVEQEFCQ
|||..||||.|.|.....|||..|| .....|.|.....||....||......|||..||.|.||....||..||.......  ||   .|||.|.|.||
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKK---SFFVMEMEKCQ

TN--LENFFTQCRLKKSYPCQQQKEVMAIQMLDSVAYLHRFDLLHRDIKPSNFLLSLDEKEIPTVKICD------LSFASALKNNKSRITVSKIKGTQAY
.|  |...|..|| |.|||.||.||..||||.|||.|||.|. .||||||.|||...|....||.|.||      . |||.|..|||.....|.|||..|
QNCNLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQY

-----------FAPEVEKGVYKKGSDVFS-------LGLVL
           |||||||..... ||.||       .||||
IEMYFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL
Kinase 13374.AA C8 135-356 38 2e-62 213.69 In-house 1-226 (226) Show / Hide 
Range on Protein: 135-356
Range on HMM: 1-226/226
Sequence Identity: 38% (88 aa)

YTDFSYSGNGAFSFVLKATNQKTGQIIALKVTECDDN-DINGMKQVEEEYRLLRQFSNCKYIVQVFNCFFLTEEESSDDDCSNDDEEEGKNEKKEKNLFF
  .| |  .||.. |||| | |  . |.||. .| .. ||... ... ||...  |.  . .| . .|| . .|.   ..|||.     |    |.  .|
FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNE-----KIVQTEEKSCF

VVEQEFCQTNLENFFTQCRLKKSYPCQQQKEVMAIQMLDSVAYLHRFDLLHRDIKPSNFLLSLDEKEIPTVKICDLSFASALKNNKSRITVSKI--KGTQ
| | | |. ||.... ..| |. .. ...|| .||||.|.| |.| .  .||||||.|||. ||.......|.||. |||... ||| |   |.   ||.
VMEMELCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTW

AYFAPEVEKG------VYKKGSDVFSLGLVL
||||||.||.       |.. ||.||.||||
AYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 13374.AA CMGC 135-312 15 4e-24 75.36 In-house 1-251 (513) Show / Hide 
Range on Protein: 135-312
Range on HMM: 1-251/513
Sequence Identity: 15% (40 aa)

YTDFSYSGNGAFSFVLKATNQKTG--------------QIIALKVTECDDNDINGMK----------QVEEEYRLLRQFS----------------NCKY
|.  .. | |... | |.....|.              .|.|.|    .  . ...|              | ..|....                . ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVQVFNCFFLTEEESSDDD----CSNDDEEEGKNEKKEKNLFFVVEQEFCQTNLENFFTQCR--------LKKSYPC----------QQQKEVM-----A
||. ...|   ........     |           ....|..|   |.....| ..  ...        .. |             .. |  |     .
IVKLYDIFYHKNSDGNEYEDKHIIS---------Q-HFNHLYLV--FEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYM

IQMLDSVA--YLHRFD--LLHRDIKPSNFLLSLDEKEI----------------PTVKICDLSFA
 |.| ...  |.|. .   .|||.||.| |.. . . |                 ..||||  .|
YQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase 13374.AA TKL 266-359 20 5.9e-20 68.54 In-house 137-282 (364) Show / Hide 
Range on Protein: 266-359
Range on HMM: 137-282/364
Sequence Identity: 20% (30 aa)

MAIQMLDSVAYLHRFD--------LLHRDIKPSNFLLSLDEK----------EIPTVKICDLSFASALKNNK-----------------SRITVSKIKGT
.|...   ..|||  .        ..|||.|..| |.  . .          .. ..||||. ..  .....                 .| | ... ||
WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGT

QAYFAPEV-----------------EKGVYKKGSDVFSLGLVLLEL
 .. ||||                 ... | . .||.| |.|| |.
PRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEI
Kinase 13374.AA S_TKc 135-421 22 5.3e-18 67.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 135-421
Range on HMM: 1-231/231
Sequence Identity: 22% (67 aa)

YTDFSYSGNGAFSFVLKATNQKTGQIIALKVTECDDNDINGMKQVEEEYRLLRQFSNCKYIVQVFNCFFLTEEESSDDDCSNDDEEEGKNEKKEKNLFFV
|.     | |||. | |... |||.| |.|.           .... | ..|..  ....||. . .|                          ..|..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD------------------------DHLYMV

VEQEFCQTNLENFFTQCRLKKS------YPCQQQKEVMAIQMLDSVAYLHRFDLLHRDIKPSNFLLSLDEKEIPTVKICDLSFASALKNNKSRITVSKIK
   |.| ..| . |.  . ...      .|  . . .|. |... ..|.|.   .|||.||.| ||.       ..||||  .|  |         . . 
M--EYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMY-QICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL---------TTFC

GTQAYFAPEVEKGVYKK-GSDVFSLGLVLLELDNMSN-FNFNDTTNEDKLEIKFAKIFPNYQIDRQSYIYKIAYQCLNYFVENRKQAIDLLI--------
||  | ||||    | |  .|. |.| .| |.      |          ..  | ||        .. .  .  .||..  |.|  | ..|         
GTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP--------QMQMMFKKIG------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCH

QFI
...
PWF
Kinase 13374.AA CAMK 269-356 21 7.7e-17 50.11 In-house 187-324 (425) Show / Hide 
Range on Protein: 269-356
Range on HMM: 187-324/425
Sequence Identity: 21% (30 aa)

QMLDSVAYLHRFDLLHRDIKPSNFLLSLDEKEIP-------------TVKICDLSFASALKNNKSRI---------------------TVSKIKGTQAYF
|... |.|.|  .  |||.|| | ||. .... .             ..||.|  ||  .. ...                         .   || .| 
QICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYM

A-PEVEKGV---------------YKKGSDVFSLGLVL
| ||| .|                | . .|. |.| .|
AAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVIL
Kinase 13374.AA Pkinase 269-359 32 9.6e-17 60.29 Pfam 116-205 (293) Show / Hide 
Range on Protein: 269-359
Range on HMM: 116-205/293
Sequence Identity: 32% (31 aa)

QMLDSVAYLHRFDLLHRDIKPSNFLLSLDEKEI-PTVKICDLSFASALKNNKSRITVSKIKGTQAYFAPEV--EKGVYKKGSDVFSLGLVLLEL
|.|  ..|.|.   .|||.||.|.|.. .. .| ..|||||  .|  .. . .    . . ||  | ||||  .   | . .|..|.|..| |.
QILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEM
Kinase 13374.AA Ciliate-E1 226-350 21 2.6e-16 49.96 In-house 65-202 (202) Show / Hide 
Range on Protein: 226-350
Range on HMM: 65-202/202
Sequence Identity: 21% (29 aa)

KKEKNLFFVVEQEFCQTNLENFFT---------QCRLKKSYPCQQQKEVMAIQMLDSVAYLHRFDLLHRDIKPSNFLLSLDEKEIPT-VKICDLSFASAL
|...|....  .|.|. .|.. ..         ||. .. .  .|||. ...|..| ...|| . ..||||||.| | . ... . .   |...   . .
KIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQN

KNNKSRITVSKIKGTQAYFAPEV--EKG-VYKKGSDVF
.. . .   .. . .. |. ||.  .|   ... ||..
QQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY
Kinase 13374.AA Ciliate-E2 264-359 21 8.1e-16 50.77 In-house 163-289 (365) Show / Hide 
Range on Protein: 264-359
Range on HMM: 163-289/365
Sequence Identity: 21% (30 aa)

EVMAIQMLDSVAYLHRFD-LLHRDIKPSNFLLSLDEKEIPTVKICDLSFAS----------------ALKNNKSRITVSKI--------------KGTQA
| .. .... . |||     .||||||.| |.         .||.|. ..                  ... |......                 ||  
EFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPG

YFAPEVEKGV----------YKKGSDVFSLGLVLLEL
| |||. .|           | . .|..||| .| |.
YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM
Kinase 13374.AA Ciliate-E2-Unclassified 225-359 24 1.6e-15 50.36 In-house 90-263 (352) Show / Hide 
Range on Protein: 225-359
Range on HMM: 90-263/352
Sequence Identity: 24% (44 aa)

EKKEKNLFFVVEQ------EFCQTNLEN-------FFTQCRLKKSYPCQQQK----EVMAIQMLDSVAYLHRFD-LLHRDIKPSNFLLSLDEK--EIPTV
.....|...| |.      ... .. ..        | ... .|  ..|| |    . .. | |.   |||.    .||||||.| |.. . |  .|   
FQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYI---

KICDLSFAS-ALKNNKSRIT-------------VSKIKGTQAYF----APEVEKG-VYK----KGSDVFSLGLVLLEL
||.|.....   .||... |              . . ||  |     |||| .|  |     . .|..||| .| |.
KIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEM
Kinase 13374.AA STE 265-359 28 1.9e-15 51.08 In-house 155-261 (359) Show / Hide 
Range on Protein: 265-359
Range on HMM: 155-261/359
Sequence Identity: 28% (33 aa)

VMAIQMLDS-VAYLHRFDLLHRDIKPSNFLLSLDEKEIPTVKICDLSFASALKNNKSRI----------TVS----KIKGTQAYFAPEVEKG-------V
... | |    .|||.    ||||||.| ||         ||.||  ... | .. ..|          | .     . ||. . |||| ..        
YICRQILKGLLYYLHSHHIIHRDIKPANILL---------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKG

YKKGSDVFSLGLVLLEL
|   .|. |||....|.
YDTKCDIWSLGCTIIEM
Kinase 13374.AA STE 135-203 21 2e-09 29.53 In-house 1-100 (359) Show / Hide 
Range on Protein: 135-203
Range on HMM: 1-100/359
Sequence Identity: 21% (21 aa)

YTDFSYSGNGAFSFVLKATNQK---------------TGQIIALKVTECDDND---------------INGMKQVEEEYRLLRQFSN-CKYIVQVFNCFF
... .  |.|||  | || | |               ||.|.| |. . ....               .. |.|...| ........ ...||. . |.|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF
Kinase 13374.AA TyrKc 135-420 18 6.2e-08 -94.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 135-420
Range on HMM: 1-280/280
Sequence Identity: 18% (58 aa)

YTDFSYSGNGAFSFVLKATNQKTGQIIALKVTECDDNDINGMKQVEEEYRLLRQF-SNCKYIVQVFNCFFLTEEESSDDDCSNDDEEEGKNEKKEKNLFF
 |     |.|||  | |.|     .  | |.   |      ..   .| |.....  . . ||. . .    ..                    .    .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-----------------FMYIEPLM

VVEQEFCQTNLENFFTQCRLKKSYPCQQQKEVMAIQMLDSVAYLHRFDLLHRDIKPSNFLLSLDEKEIPTVKICDLSFASALKNN------KSRITVSKI
.|    .  .| ..   .| |    | ...  ...|  .  .|||.  . |||.   | |.. .     ||||.|   . ....       |. ..... 
IVMEYMPHGDLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEH

KGTQ-----AYFAPEVE-KGVYKKGSDVFSLGLVLLEL--------DN-----MSNFNFNDTTNEDKLEIKFAK----IFPNYQIDRQSYIYKIAYQCLN
||.         |||.  .|..   |||.| | .. |.         .     |||.       . .   . .      |        . .|.|  || .
KGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF----VCCPDEMYQIMKQCWH

YFVENRKQAIDLLIQF
.  |.|    ..  .|
EDPEDRPTFSEIHECF
Kinase 13374.AA Ciliate-E1 142-206 27 6.8e-08 22.26 In-house 2-68 (202) Show / Hide 
Range on Protein: 142-206
Range on HMM: 2-68/202
Sequence Identity: 27% (19 aa)

GNGAFSFVLKATNQKTG-QIIALKVTECDDN--DINGMKQVEEEYRLLRQFSNCKYIVQVFNCFFLTE
||| ||.|.|| .|..  . .|.|. .| .|  ...  .. .|.| ..  | . .||.|....... .
GNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQ
Kinase 13374.AA Pkinase 142-202 23 2.9e-05 19.71 Pfam 8-69 (293) Show / Hide 
Range on Protein: 142-202
Range on HMM: 8-69/293
Sequence Identity: 23% (15 aa)

GNGAFSFVLKATNQKTGQIIALKVTECDDNDINGMKQVEE--EYRLLRQFSNCKYIVQVFNCF
| |.|. | |.....||.| |.|. . .... .  ..     | .... . |...||. . .|
GSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWF
Kinase 13374.AA CAMK 142-202 12 6.6e-05 10.96 In-house 3-107 (425) Show / Hide 
Range on Protein: 142-202
Range on HMM: 3-107/425
Sequence Identity: 12% (13 aa)

GNGAFSFVLKATNQKTG------------QIIALKV----TECDDN----------------------DINGMKQVEEEYRLLRQFS------NCKYIVQ
| |.|. | .... .|.            |  | |.       |..                      . . .|.|. |...... .      . . |..
GRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIK

VFNCF
 .  .
LYEVY
Kinase 13374.AA Ciliate-E2-Unclassified 135-202 18 0.005371 6.26 In-house 1-90 (352) Show / Hide 
Range on Protein: 135-202
Range on HMM: 1-90/352
Sequence Identity: 18% (17 aa)

YTDFSYSGNGAFSFVLKATNQKTGQI----IALKVTECDDNDING-------MKQVEEEY--------RLLR---QFSNCKYIVQVFNCF
|.     |.|.|. | |. . |..|.    .. |. ..... |.        ||....          ...    . ... .||  | ||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCF
Kinase 13374.AA Ciliate-E2 142-202 17 0.076352 2.09 In-house 26-119 (365) Show / Hide 
Range on Protein: 142-202
Range on HMM: 26-119/365
Sequence Identity: 17% (17 aa)

GNGAFSFVLKATNQKTGQIIALKVTECDD----------------------NDINGMKQVEEEYRLLR------------QFSNCKYIVQVFNCF
|.|.|. | |... |... .|.|. . .                       |.|. .||.. ..| ..            .. |...|.. . ||
GQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECF
Kinase 13374.AA C2 503-617 44 4.6e-68 231.56 In-house 1-145 (245) Show / Hide 
Range on Protein: 503-617
Range on HMM: 1-145/245
Sequence Identity: 44% (64 aa)

SAKGLVLGTFNKTLGIKTVLKIQQVQS-----KHEVVQEVGIMRDCQ-MPLVIKFYGYFYLSVNKQDD------------------------FVVYEIEK
.|.||||..|||. .....||||..||     .|||..|.||||.|| ||..||.|.||||.|||..|                        |||||.|.
GAFGLVLKAFNKKQNRHVALKIQECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQEF

CSGNLKQYLTRLQKENIVLTDNQKMQIAVQIIDVVNYLNYNGIVH
|.||||||..|..|.|.......||..|.|..|..|||....|||
CQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVH
Kinase 13374.AA Ciliate-C8 503-617 35 2.5e-49 170.17 In-house 1-142 (238) Show / Hide 
Range on Protein: 503-617
Range on HMM: 1-142/238
Sequence Identity: 35% (50 aa)

SAKGLVLG-------TFNKTLGIKTVLKIQQVQSKHEVVQEVGIMRDCQMPLVIKFYGYFYLS-VNKQDD-----------------FVVYEIEKCS--G
 |.|.||.        ...   .. |.|||..|..||......||..||||.|...|..|||. .||..|                 |.|.|.|||.  .
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNC

NLKQYLTRLQKENIVLTDNQKMQIAVQIIDVVNYLNYNGIVH
|||||..|..|... .....|..||.|.||.||||... |.|
NLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMH
Kinase 13374.AA C8 494-617 26 2.7e-17 56.66 In-house 1-146 (226) Show / Hide 
Range on Protein: 494-617
Range on HMM: 1-146/226
Sequence Identity: 26% (39 aa)

YETILKLLQSAKGLVLGTFNKTLGIKTVLKIQQVQSKHEVVQEVGIMRDCQMPLVIKFYGYFYLS-VNKQDDFVVYEIEKCS------------------
 .    | . |.|.|| . |     . |||.|..|.|..  ..  ||. ..||.|.. |  ...  . ......|.| ||||                  
FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEME

---GNLKQYLTRLQKENIVLTDNQKMQIAVQIIDVVNYLNYNGIVH
    ||||.   .....  .....| .||.|.|| |||..   |.|
LCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMH
Kinase 13374.AA Ciliate-E1 500-617 19 2.2e-08 23.87 In-house 1-132 (202) Show / Hide 
Range on Protein: 500-617
Range on HMM: 1-132/202
Sequence Identity: 19% (26 aa)

LLQSAKGLVLGTFNKTLG-IKTVLKIQQVQSKHEVVQEVGIMRDCQMPLVIKFYGYF--YLSVNKQDD--FVVYEIEKCSGNLKQYLT---------RLQ
. ..  ..|.  ...    ..  .||.... . . ...  . . .. .. .|.. |   .. . |.|.  . .  .|.|. .||.||.          .|
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQ

KENIVLTDNQKMQIAVQIIDVVNYLNYNGIVH
.... .|. |||||..|.|| ...| ...| |
QNQNQFTFQQKMQIIFQLIDGLIELHQYNIIH
Kinase 13374.AA Ciliate-E2 522-617 19 0.000464 9.81 In-house 52-184 (365) Show / Hide 
Range on Protein: 522-617
Range on HMM: 52-184/365
Sequence Identity: 19% (27 aa)

LKIQQVQSKHEVVQEVGIMR----------------DCQMPLVIKFYGYFYLSVNKQDDFVVYEIEKCSG-NLKQYLT--RLQKENI-----VLTDNQKM
.||.. . . .. ||  |||                  . | .||.| .|.   .|.|. . .  | |.| .|..|.   .... ..      .|...  
MKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQ---EKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIK

QIAVQIID---------------VVNYLNYNG-IVH
.|  ||..                ..||  .. |.|
YIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIH
Kinase 13374.AA Ciliate-E2-Unclassified 521-617 16 0.02888 3.69 In-house 50-167 (352) Show / Hide 
Range on Protein: 521-617
Range on HMM: 50-167/352
Sequence Identity: 16% (21 aa)

VLKIQQVQSKH--------EVVQEVGIMRDCQMPLVIKFYGYFYLSVNKQDDFVVYEIEKC-SGNLKQYLT-------------RLQKENIVLTDNQKM-
.........|            |.  |......|...|.. .|     .... .    |.|  |.|.||..             . .|..  .|..|   
MNEMKEMNNKKKYHQRKYNKIMQQ--ILLNHPHPFIVKMFYCF-----QDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKY

----QIAVQIIDVVNYLNYNG-IVH
    ... ||..  .|| ... |.|
KKAKFYFAQILQGLEYLHHKNNIIH
Kinase 13374.AA CMGC 571-617 14 0.033487 1.99 In-house 135-207 (513) Show / Hide 
Range on Protein: 571-617
Range on HMM: 135-207/513
Sequence Identity: 14% (11 aa)

EKCSGNLKQYLTRLQK-----ENIVLTDNQ------------KMQIA------VQIIDVVN--YLNYNG--IVH
| .  .|.||. . |.      .. |.. .            .  .        ||.  ..  |.  ..  |.|
EYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIH
Kinase 13374.AA STE 522-617 19 0.07131 2.55 In-house 64-175 (359) Show / Hide 
Range on Protein: 522-617
Range on HMM: 64-175/359
Sequence Identity: 19% (22 aa)

LKIQQVQSKHEVVQEVGIMRDCQ--MPLVIKFYGYFYLS---VNKQDDFVVYEIEKCS-GNLKQYLTRLQKENIVLT----------DNQKMQIAVQIID
|.. . . . .. .|. ||..|.   | ..|.||...      .  |.  ..  | .. | | . . .  . .  |.           .|   |..||. 
LENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWIC-MEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILK

V-VNYLNYNGIVH
   .||  ..|.|
GLLYYLHSHHIIH