Gene 6129 (Tetrahymena)

6129

Species: Tetrahymena
Alias: 34.m00366, TTHERM_00339880, 609, PreTt06129, 3689.m00160, 6129
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2

Sequence

Name Sequence Type Origin Length Description Download
6129.AA Protein None 309 None Fasta, JSON
6129.kin_dom Protein Kinase Domain None 290 None Fasta, JSON
6129.NA RNA None 930 None Fasta, JSON

Protein domain

Protein domains of 6129.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 6129.AA CDC2 17-306 51 8.70000000001e-202 626.59 In-house 1-301 (301) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-301/301
Sequence Identity: 51% (160 aa)

FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGD-GFPSSSMREISTLKKMK-HENIVILKDVQFQFDENSLLMVFECLECDLKQYLENEFP--
.|||...||||||.|.||.|.||...||.|||.|| .. . |.||...||||.||..| |.||| |.||..|   |.| ||||.|..|||.|.....|  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

--IQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYT--KEIATLWYRAPEVMLGDEHYSITIDIWAVG
  ..|...|..|.||||||..|||..||||||||||||...|.|    .||.|||||..|..|...||  .|. ||||||||..||...||...|.|..|
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN----IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIG

CIFIEL---ITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNEKFPKFQAQGIQKLLPS-------NFNDPEALDLLSNLLVLDPSRRIFSK
|||.|.   .||.|.||..|.|||||.||.|.|||||||.||...||||...||....|...|..|.        ..|||..|||...|..||..||..|
CIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAK

EALKHPYF
|||.||||
EALQHPYF
Kinase 6129.AA CDK 17-306 43 1e-159 514.82 In-house 1-284 (284) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-284/284
Sequence Identity: 43% (138 aa)

FQKIKMLGEGTYGHVTKCQDKQTK-----EVVAVKKIKLEIF----QGDGFPSSSMREISTLKKMKHENIVILKDVQFQFD---------ENSLLMVFEC
..|.. .||||||.| |..||||.     ..|| |||..|       ..|||... ||||.||.. |.||| |.||  . .         ||.| |||| 
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

LECDLKQYLENEFPIQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNT-MSVKISDFGLAKTFTT------PLDKYTKEIATLWYRAPEV
.. |||.|..         || .|.|.|.|..|||.  ||||||||||||.. . ... ...|| |||||. |        |. .||.|. ||||||||.
MDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL

MLGDEHYS--ITIDIWAVGCIFIELIT---KRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNEKFPKFQAQGIQKLLPSNFNDPEALDLLSNL
 ||..|||   .||.|.|||||.|..|   ..| |. .| ||||| ||.|.|||.|.. ||..|||||                          |||...
LLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------DLLNKM

LVLDPSRRIFSKEALKHPYF
|..||..|| ...||.||||
LCYDPKKRISAEQALQHPYF
Kinase 6129.AA CMGC 17-306 27 3e-132 437.26 In-house 1-513 (513) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-513/513
Sequence Identity: 27% (139 aa)

FQKIKMLGEGTYGHVTKCQD--------------KQTKEVVAVKKIKLEIFQ--------GDGFPSSSMREISTLKKMK-----------------HENI
...|| .|||||| | ||.|              ..|.|.||.||||.. ..        .||||... |||. ||...                 |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VILKDVQFQFD---------------ENSLLMVFECLECDLKQYLENEF---------PIQPIK------------IKQIM------KQILQGVD--YCH
| |.|.    .               .|.| .|||....||.||..|           |  . .            || .|      .|||.|..  |||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

QMQ--IMHRDLKPQNILVSTKANN----------------TMSVKISDFGLAKTFTTPLDK---------------------YTKEIATLWYRAPEVMLG
..   |.||||||.|||.. .  .                 . .|| |||||. . .. |.                     || ...|.||||||..||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

DEHYS---------ITIDIWAVGCIFIELITK--------RPPFH-----------AQSQIDQLFQIFQIFGTPN---------------EQTYPGISKL
..||.          .||.|.||||| |..|.        .| |.            .| |||||.||...|||.               |...|...||
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PDY----------------NEK----------FPKFQAQGIQKLLPSNFN---------------------------------DPEALDLLSNLLVLDPS
|.|                .|.          ||... . ...| | . |                                 ||.|.|||...|..||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

RRIFSKEALKHPYF
.||  ..||.||||
KRITAEQALQHPYF
Kinase 6129.AA CDK5 17-306 42 1.3e-115 366.92 In-house 1-287 (287) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-287/287
Sequence Identity: 42% (126 aa)

FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMREISTLKKMKHENIVILKDVQFQFDENSLLMVFECLECDLKQYLEN-EFPIQP
..|.  .|||||| | | ..|.|.|.|| |...|.     | ||. .|||. || .||.||| | ||     |. | .||| .  ||| |... .  ...
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDS-EDEGVPSTAIREICLLKELKHKNIVRLHDVIHS--EKKLTLVFEFCDQDLKKYMDSCNGEMDM

IKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDIWAVGCIFIELI
  || .| | |.|. .||. ...|||||||| |.... .     |  |||||  |  |   |. |. |||||.| |..|  |||  ||.| .|||| |..
HIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGE----LKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMA

-TKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYN---EKFPKFQAQG-IQKLLPSNFNDPEALDLLSNLLVLDPSRRIFSKEALKHPYF
 . || |   .. |||..||.| |||.| . |.|.|||||.   ...|...|.   |.. |.   | . .|||...|...|  ||  |.||.||||
NAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPK--LDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 6129.AA CDK7 17-306 36 1.6e-112 301.06 In-house 1-288 (288) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-288/288
Sequence Identity: 36% (110 aa)

FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIK----LEIFQGDGFPSSSMREISTLKKMKHENIVILKDVQFQFDENSLLMVFECLECDLKQYLE-NEF
..||| .|||... | | .|.|| ..||.||||     . .. ||   . .|||  |. |.|.|.. | |.  . .  .. .||. .. ||    . .. 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAK-DGINRTAIREIKILQEMQHDNVIGLIDIFMHKS--NIQLVFDFMDWDLEVVIKDKSI

PIQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDIWAVGCIF
   |  || .|...|||. |||.  | |||||| | |..        .|| |||||. .  |   ||  . | ||||||   |  ||   .|.|.|||||
ILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQ----LKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIF

IELITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNEKFPKFQA---QGIQKLLPSNFNDPEALDLLSNLLVLDPSRRIFSKEALKHPYF
 ||.   | .  .| ||||  |||. |||.|.. |......||. || .| .      ...     .|  .|||.. .. ..|..|.   ..||.|||
AELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYI-KFKDFPGYSRTPLRHIFTAASDD--LLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 6129.AA S_TKc 17-306 29 9.1e-98 332.03 SMART 1-231 (231) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-231/231
Sequence Identity: 29% (91 aa)

FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMREISTLKKMKHENIVILKDVQFQFDENSLLMVFECLEC---DLKQYLENEFP-
..... .|.|..| | ||..| |...||.|.||           . .|||. ||| .|.||| |.||      ..| ||.|...    ||..|...  . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----IQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSI-TIDIWA
     . .  .. .|.||.....|||...|.||||||.|||...       .||.|||||. .       |  . |.||.||||.    .|.   .|.|.
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWS

VGCIFIELITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNEKFPKFQAQGIQKLLPSNFNDPEALDLLSNLLVLDPSRRIFSKEALK----
.|||..|... .|||.      |....|.. |                                     .|||.|.....|. ||..|.   |||.    
CGCILYEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWD

---HPYF
   ||.|
IKCHPWF
Kinase 6129.AA PITSLRE 17-306 42 2.8e-94 319.51 In-house 1-295 (295) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-295/295
Sequence Identity: 42% (126 aa)

FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLE-IFQGDGFPSSSMREIS-TLKKMKHENIVILKDVQFQFDENSLLMVFECLECDLKQYLENEF---
||..   .||||| | . .||.| |.|| |..|.|     .|||  |.|||.  |. ..|.||| .| .    . ..  ||.| .| |||  .||     
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

-PIQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDIWAVGCI
 | .|  ||  | | | ||.. |   |||||||  |.| | | .     || |||||  .  |. .||. . ||||||||. || . ||  .|.| ||||
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGI----LKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCI

FIELITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNE-K-FPKFQAQGIQKLLP--SNFNDPEALDLLSNLLVLDPSRRIFSKEALKHPYF
| |.||..| |  .| |||. .||. .|||.|.  ||...||  .  . ||.       |. |     .|  ..|||  .| ..| .||   .|||||.|
FAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISD-TGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase 6129.AA PCTAIRE 17-306 40 3e-85 289.54 In-house 1-291 (291) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-291/291
Sequence Identity: 40% (120 aa)

FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMREISTLKKMKHENIVILKDVQFQFDENSLLMVFECLECDLKQYLE-NEFPIQP
. |.  ||||||  | ||. | |  .|| | |.|| ..  | |    ||.| || .|| ||| | |. ..  . .| .||| .. |||||.. .   .. 
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLE-HE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHT--HHQLTLVFEYMDMDLKQYMDDCGNIMNM

IKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDIWAVGCIFIELI
. .| .. |.| | .|||. .|.|||||||| |.    |     |  |||||.    |   | .|. ||||| |.|..|   ||  ||.| ||||| |. 
HNVKLFLFQLLRGLAYCHRRKILHRDLKPQNLLI----NERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMC

TKRPPFHAQS------QIDQLFQIFQIFGTPNEQTYPGISKLPDY-NEKFPKFQAQGIQKLLPSNFN--DPEALDLLSNLLVLDPSRRIFSKEALKHPYF
| || |            |||  ||.| ||| |.| ||.. .... .. ||....| .    |  .     .  |||..|| . .  |.   .|.|||||
TGRPLFPGSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAP-RLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase 6129.AA RCK 17-306 38 3.9e-85 270.06 In-house 1-298 (298) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-298/298
Sequence Identity: 38% (118 aa)

FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPS----SSMREISTLKKMK-HENIVILKDVQFQFDENSLLMVFECLECDLKQYLEN--
 | || ||.|||| |.| |.| |.|.|| || |        |.|     . |||  |.|.. |.||. ||.| .. |. .|  |||... .| |....  
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK------QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFK

--EFPIQPIK--IKQIMKQILQGVDYCHQMQIMHRDLKPQNILVST-----KANNTMSVKISDFGLAKTFTTPLDK--YTKEIATLWYRAPEVMLGDEHY
  . ... ..  || ||.||||| ...|   ..|||||| ||...         ..  .|| ||||.. .    .|  ||  . | ||||||. | . .|
ERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIR---SKPPYTDYVSTRWYRAPECLLRCTYY

SITIDIWAVGCIFIELITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYP-GISKLPDYNEKFPKFQAQGIQKLLPSNFNDPEALDLLSNLLVLDPSRRIFS
.  .||||||||..|| ..|| |  .| |||.|.| .. |||| ...| |. .    | .||. .......|.|.    .....|.  .|  ||. ||  
NSPMDIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPN--CSQDCIELMEKMLQWDPQKRITA

KEALKHPYF
..||.||||
QQALQHPYF
Kinase 6129.AA Pkinase 17-306 32 8e-85 292.91 Pfam 1-293 (293) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-293/293
Sequence Identity: 32% (100 aa)

FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMR--EISTLKKMKHENIVILKDVQFQFDENSLLMVFECLEC-----DLKQYLE-
..... .|.|..| | ||..| | ..||||.||..  . .... .  |  ||. .|...|.||| |.|.     .... ||.|..|.     ||. |.. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

-NEFPI--QPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTF-TTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDI
 .. ..  ..  .| .|.|||.|..|||.| |.||||||.|||.. . ..  .|||.|||||| | . .   .|    |.||.|||| .|...|.  .|.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WAVGCIFIELITKRPPFHAQ----SQIDQLFQIFQIFGTPNEQTYP-GISKLPDYNEKFPKFQAQGIQKLLPSNFNDPEALDLLSNLLVLDPSRRIFSKE
|..|||..|....||||  .    . .||.. |..| |.|..  .|  .|. ...  .. .     . ...  | . .|..|.....| .||..|.  ..
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---FHWTF-HNWS-EECKDFIKWCLCKDPKKRPTAEQ

ALKHPYF
.|.||.|
ILQHPWF
Kinase 6129.AA CRK7 17-306 34 1.7e-83 283.66 In-house 1-343 (343) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-343/343
Sequence Identity: 34% (120 aa)

FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIF--QGDGFPSSSMREISTLKKMKHENIVILKDVQFQ--------FDENSLLMVFECLECDLKQY
...|.  |||||| | | ..|.|.| || ||....    . .|||  . |||  |. ..|.||| ||..            .  |  ||||    ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LENE-FP-IQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPL--DKYTKEIATLWYRAPEVMLGDEHY----
||.  .  . .  .| .|||.| |.||||.  ..|||.|  |||.    ||   ||| |||||  .       .||  . |||||.||  ||.|.|    
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILM----NNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQH

----------------------------------SITIDIWAVGCIFIELITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNEKFPKFQAQ
                                     ||.| .|||..|| ||.| | ..  ..||  |..| |.|| .  | . ||| .|   ||   .
ILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPK---R

GIQKLLPSNFN--------DPEALDLLSNLLVLDPSRRIFSKEALKHPYF
  . .|  .|         ..|.|||| ..|.|||. |.  .|.| |..|
QYNRRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 6129.AA PFTAIRE 17-306 38 2.3e-83 283.25 In-house 1-287 (287) Show / Hide 
Range on Protein: 17-306
Range on HMM: 1-287/287
Sequence Identity: 38% (114 aa)

FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMREISTLKKMKHENIVILKDVQFQFDENSLLMVFECLECDLKQYLEN-EFPIQP
..|.. ||||.|  | |   . .. .|| | |.|.  |  | |    || | || .|| |||.| |.     .  | .||| .. ||.||..     ..|
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ--QEEGTPFTAIREASLLKNLKHANIVCLHDIIHT--KETLTFVFEYVHTDLCQYMDKHPGGMHP

IKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDIWAVGCIFIELI
  ..  . | | |  |||| ...|||||||| |.| .       |  |||||     |   | .|. ||||| | |.||   ||  .|.| |||||.|..
NNVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGE----LKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMM

TKRPPFHAQ-SQIDQLFQIFQIFGTPNEQTYPGISKLPDYN-EKFP--KFQAQGIQKLLPSNFNDPEALDLLSNLLVLDPSRRIFSKEALKHPYF
. .| |       ||| .||.. |||.|.|.||...|| |. ..|.   .. .  .. .|.  . |.| ||....| . |  |.  .||..||||
WGQPAFPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase 6129.AA Pkinase_Tyr 17-169 32 3.7e-18 62.14 Pfam 1-160 (270) Show / Hide 
Range on Protein: 17-169
Range on HMM: 1-160/270
Sequence Identity: 32% (56 aa)

FQKIKMLGEGTYGHVTKCQDK----QTKEVVAVKKIKLEIFQGDGFPSSS------MREISTLKKM-KHENIVILKDVQF-QFDENSLLMVFECLEC-DL
 ...|.|||| .|.| |.  |    .||  ||||..|      .|  ..       |||....|.. .|.||| |  |   | . |....|.|  .. ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL

KQYLEN----EFPIQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKT
. || .    . |. .  . |.  || .| .| ..... ||||   |.||.     .. |||.|||||..
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLARD
Kinase 6129.AA TyrKc 17-286 25 4.5e-13 -11.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 17-286
Range on HMM: 1-280/280
Sequence Identity: 25% (76 aa)

FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMREISTLKKM--KHENIVILKDVQFQFDE-----NSLLMVFE-CLECDLKQYLE
 ...|.|||| .| | |.. |   . ||||..| .           |||.. ..|   .|.||| |  |  |  .       |..|.| .   |||.|| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NEFP-IQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTP------LDKYTK-----EI--ATLWYRAPEVMLG
.  | ... .  ... || .| .| |.... ||||   |.||. .      ||||||||..  .         | |.|     .     .   |||..  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

DEH-YSITIDIWAVGCIFIELITK-RPPFHA-----QSQIDQLFQIFQIFGTPNEQT-YPGISKLPDYNEKFPKFQAQGIQKLLPSNFND-PEALDLLSN
... ...  |.|. |    |. |   .|         | .. . .. | .  |  .  || .|    .    |.   | ...    . .| |   .. . 
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS----F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

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