Gene 9119 (Tetrahymena)

9119

Species: Tetrahymena
Alias: 9119, TTHERM_01207660, 1132, PreTt09119, 274.m00036
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK5

Sequence

Name Sequence Type Origin Length Description Download
9119.AA Protein None 779 None Fasta, JSON
9119.kin_dom Protein Kinase Domain None 284 None Fasta, JSON
9119.NA RNA None 2340 None Fasta, JSON

Protein domain

Protein domains of 9119.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 9119.AA CDK5 11-294 67 2.8e-230 735.6 In-house 1-287 (287) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-287/287
Sequence Identity: 67% (195 aa)

YEKLNKLGEGTYGVVYKAREKTTKELYALKKIRLESEDEGIPSTAIREISLLKELQHPNVVRLHDVIHSNKKLVLVFEFVDQDLKKFMNNFKDKGLDPHI
|||..|.||||||.|||||.|.|.|..|||..||.|||||.||||||||.|||||.|.|.|||||||||.|||.|||||.||||||.|..... ..|.||
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNG-EMDMHI

IKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECILKLADFGLARASGIPVKNYTHEVVTLWYRPPDVLLGSKHYSTSIDIWSIGCIFAEMV-NLKPL
|||..||||||...||....||||||||||||.|...|||||||||||.||||..|.||||||||||||||.||||||||||.||.|||||||. ...||
IKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPL

FPGNSETDELKRIFKLTGTPCVEKWPGLADLPNWK--ADAFEKYPGEP-LQNICPKLDELGLDLLGKMLRCNPQERITAKAGLEHPYF
||||...|.||||||..||||..|||....||..|  ......||... .|.|.||||| |.|||.|||.|||..||.|||.|.||||
FPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 9119.AA CDC2 11-294 55 1.3e-185 576.02 In-house 1-301 (301) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-301/301
Sequence Identity: 55% (169 aa)

YEKLNKLGEGTYGVVYKAREKTTKELYALKKIRLESEDEG--IPSTAIREISLLKELQ-HPNVVRLHDVIHSNKKLVLVFEFVDQDLKKFMN-NFK-DKG
|.|..|.||||||||||.... |... ||||||||.||||  .|||||||||.||||. |||.|.||||||. .|| .|||..|.||||.|   .. .| 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LDPHIIKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECILKLADFGLARASGIPVKNYT--HEVVTLWYRPPDVLLGSKHYSTSIDIWSIGCIFAEM
..|...||..||.|.|.. || ..|.||||||||.||.|.  .|.|||||||| |||...||  |||||||||.| .|||.|.|||..|.||||||||||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---VNLKPLFPGNSETDELKRIFKLTGTPCVEKWPGLADLPNWKADAFEKYPGEPLQNICPK---------LDELGLDLLGKMLRCNPQERITAKAGLEH
   |. ||||.| || |.| .||.  |||  ..|||. .|| .|.. | ...   |..|||.         ||. |.||| .||. .|| ||.||. |.|
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNT-FPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQH

PYF
|||
PYF
Kinase 9119.AA CDK 11-294 50 1.8e-183 592.02 In-house 1-284 (284) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-284/284
Sequence Identity: 50% (162 aa)

YEKLNKLGEGTYGVVYKAREKTTK-----ELYALKKIRLES-----EDEGIPSTAIREISLLKELQHPNVVRLHDVIHSN-----------KKLVLVFEF
||||.|.|||||||||||| | |.     ...||||||.|.     |.||.|.|||||||||||| |||.|.||||.|..           .||..|||.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

VDQDLKKFMNNFKDKGLDPHIIKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECI-----LKLADFGLARASGI------PVKNYTHEVVTLWYRPP
.|.||||.|            ||....|||.|.. ||.|.|.||||||||.||..  .     ||.|||||||| ||      |.. |||||||||||.|
MDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

DVLLGSKHYS--TSIDIWSIGCIFAEMVN---LKPLFPGNSETDELKRIFKLTGTPCVEKWPGLADLPNWKADAFEKYPGEPLQNICPKLDELGLDLLGK
..||||||||  |.||.||.|||||||..    ||||||.||.| |..||.. |||. . |||. .||..                         ||| |
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNK

MLRCNPQERITAKAGLEHPYF
|| ..|. ||.|.. |.||||
MLCYDPKKRISAEQALQHPYF
Kinase 9119.AA CMGC 11-294 27 1.5e-148 491.88 In-house 1-513 (513) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-513/513
Sequence Identity: 27% (143 aa)

YEKLNKLGEGTYGVVYKARE--------------KTTKELYALKKIRLES---------EDEGIPSTAIREISLLKELQ-----------------HPNV
||...|.||||||||||.|               . |.|..|.|||...          | .|.|..|.|||..||.|.                 |.|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VRLHDVIHSNK-----------------KLVLVFEFVDQDLKKFMNNFKD-------KGLDPHI------------IKSLL------YQLLKGIE--VCH
|.|.|......                 .| ||||..|.||.... | ..       ..|..              ||...      ||.|.|..   ||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

KNK--ILHRDLKPQNLLISKECIL--------------------KLADFGLARASGIP---------------------VKNYTHEVVTLWYRPPDVLLG
...  |.||||||.|.||...| |                    |..||||||. ...                     .. |||.|||.|||.| .|||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

SKHYS---------TSIDIWSIGCIFAEMVN--------LKPLFPGNSE-----------TDELKRIFKLTGTPC---------------VEKWPGLADL
.|||.         |.||.||.|||||||..        .||||||.||            | |..|||. |||.                |.||.  .|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PNW---------------KADA----------FEKYPGEPLQNICPK-----------------------------------LDELGLDLLGKMLRCNPQ
|..               . .           | ..|. |..|..|.                                   .|....||| |||...|.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

ERITAKAGLEHPYF
.||||.  |.||||
KRITAEQALQHPYF
Kinase 9119.AA CDK7 11-294 44 8.3e-142 380.63 In-house 1-288 (288) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-288/288
Sequence Identity: 44% (130 aa)

YEKLNKLGEGTYGVVYKAREKTTKELYALKKIR----LESEDEGIPSTAIREISLLKELQHPNVVRLHDVIHSNKKLVLVFEFVDQDLKKFMNNFKDKG-
|||. ..|||....||||... | .  | |||.     .  . ||  |||||| .|.|.||.||. | |..     . |||.| | ||       |||  
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVI---KDKSI

-LDPHIIKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECILKLADFGLARASGIPVKNYTHEVVTLWYRPPDVLLGSKHYSTSIDIWSIGCIFAEMV
 | |  ||.   ..|.|.| ||.| |||||||| |||.... .||.|||||||. | | ..||| ||| ||| |  | | .|| |..|.||.||||||  
ILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELM

NLKPLFPGNSETDELKRIFKLTGTPCVEKWPGLADLPNWKADAFEKYPG---EPLQNICPKLDELGLDLLGKMLRCNPQERITAKAGLEHPYF
   | .|| |. | |.|||.  |||  |.||..  ...     | ..||    ||..|     .  |||. .|.  ||..|.|.   |..|||
LRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYI--KFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 9119.AA PFTAIRE 11-294 51 9.40000000001e-140 470.58 In-house 1-287 (287) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-287/287
Sequence Identity: 51% (148 aa)

YEKLNKLGEGTYGVVYKAREKTTKELYALKKIRLESEDEGIPSTAIREISLLKELQHPNVVRLHDVIHSNKKLVLVFEFVDQDLKKFMNNFKDKGLDPHI
||||.|||||.|  |||.. . .. . ||| |||. ..|| | ||||| ||||.|.| |.| |||.||  . | .|||.|. ||...|.     |..|. 
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ-QEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPG-GMHPNN

IKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECILKLADFGLARASGIPVKNYTHEVVTLWYRPPDVLLGSKHYSTSIDIWSIGCIFAEMVNLKPLF
..  |.||| |   ||. ..|||||||||||||.   |||||||||||  .| . | |||||||||||||||||  |||..|.| .|||| ||.  .|.|
VRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAF

PGN-SETDELKRIFKLTGTPCVEKWPGLADLPNWKADAFE--KYPGEPLQNICPKLD--ELGLDLLGKMLRCNPQERITAKAGLEHPYF
||    || | .|||. |||  ..|||   |||.|  .|.   |  ..|... |...    . ||. |||.|.|..|. |.. ..||||
PGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase 9119.AA PCTAIRE 11-294 52 6.7e-137 461.11 In-house 1-291 (291) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-291/291
Sequence Identity: 52% (154 aa)

YEKLNKLGEGTYGVVYKAREKTTKELYALKKIRLESEDEGIPSTAIREISLLKELQHPNVVRLHDVIHSNKKLVLVFEFVDQDLKKFMNNFKDKGLDPHI
| ||.|||||||  ||| | | |  | ||| |||| | || | |||||.||||.|.| |.| |||.|| .. | ||||. |.|||..|..    ... | 
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCG-NIMNMHN

IKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECILKLADFGLARASGIPVKNYTHEVVTLWYRPPDVLLGSKHYSTSIDIWSIGCIFAEMVNLKPLF
.| .|.||| |   ||. ||||||||||||||  .  |||||||||||  .| | | ||||||||||||||.||  |||.||.| .||||.||   .|||
VKLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLF

PGNS------ETDELKRIFKLTGTPCVEKWPGLADLPNWKADAFEKYPGEPLQNICPKLD---ELGLDLLGKMLRCNPQERITAKAGLEHPYF
||          |.|  ||.. |||  ..|||   ......  | .|. .|| |  |.||   . . |||...|.  ...|. | . ..||||
PGSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase 9119.AA PITSLRE 11-294 49 1.1e-128 433.87 In-house 1-295 (295) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-295/295
Sequence Identity: 49% (147 aa)

YEKLNKLGEGTYGVVYKAREKTTKELYALKKIRLE--SEDEGIPSTAIREIS-LLKELQHPNVVRLHD-VIHSNK-KLVLVFEFVDQDLKKFMNNFK--D
...||. .||||||||.|..| | |  |||.. .|   | ||.| |..|||. .|..|||||.| .   |. ||. |  .|.|.|. |||  | | |  .
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

KGLDPHIIKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECILKLADFGLARASGIPVKNYTHEVVTLWYRPPDVLLGSKHYSTSIDIWSIGCIFAEM
.   |  ||.|. |||.|.|  |.|.|.|||||  |||.| . |||..||||||  | |.| ||  ||||||| | .|||.| ||| .|.||.||||||.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

VNLKPLFPGNSETDELKRIFKLTGTPCVEKWPGLADLPNWKADA-FEKYPGEPLQNICP---KLDELGLDLLGKMLRCNPQERITAKAGLEHPYF
. .||||.|.||.|....|||. |||    |||  .||.||.   |..||   | .. |   .. . |.||| .||  ||..|||| ..| ||.|
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase 9119.AA CDK4 11-294 43 2e-112 379.79 In-house 1-290 (290) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-290/290
Sequence Identity: 43% (128 aa)

YEKLNKLGEGTYGVVYKAREKTTKELYALKKIRLESEDE--GIPSTAIREISLLKELQ---HPNVVRLHDVIH------SNKKLVLVFEFVDQDLKKFMN
|.... .||| || ||.||   |   .|||..|  ...|  |.|   |||||... |.   |||.|.| || |      .  |. .||| .|.||. .. 
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

NFKDKGLDPHIIKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECILKLADFGLARASGIPVKNYTHEVVTLWYRPPDVLLGSKHYSTSIDIWSIGCI
.    |. |  || .  ||| |..  | . | ||||||||.|.. .  .|||||||||  .   .  |  ||||||| | ||| |  | | .|.||.|||
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMA-LTPVVVTLWYRAPEVLLQSY-YNTPVDMWSVGCI

FAEMVNLKPLFPGNSETDELKRIFKLTGTPCVEKWPGLADLPNWKADAFEKYPGEPLQNICPKLDELGLDLLGKMLRCNPQERITAKAGLEHPYF
|||| . .|||.|.|| | | .||...|.|  . ||    ||    |.|  .   |.. .|| ....|.||| |||. |.. |..| ..|.||||
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLP---WDHFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase 9119.AA S_TKc 11-294 29 3.4e-103 350.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-231/231
Sequence Identity: 29% (89 aa)

YEKLNKLGEGTYGVVYKAREKTTKELYALKKIRLESEDEGIPSTAIREISLLKELQHPNVVRLHDVIHSNKKLVLVFEFVDQ---DLKKFMNNFKDKG--
||.|.|.|.|..|.|||.|.| |....|.|.|.          ...|||..||. .|||.|.|.||... ..| .|.|..|.   ||.... . . .|  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LDPHIIKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECILKLADFGLARASGIPVKNYTHEVVTLWYRPPDVLLGSKHYST-SIDIWSIGCIFAE
  ...  .....||.....| ||...|.||||||.|.|...   .|..||||||         |. ..|.||..| ||    .|.. ..|.||.|||..|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MVNLKPLFPGNSETDELKRIFKLTGTPCVEKWPGLADLPNWKADAFEKYPGEPLQNICPKLDELGLDLLGKMLRCNPQERITAKAGLE-------HPYF
|.  .|.||      .....||. |                                    .. ..|.. |.|. .|..|.||   |.       ||.|
MLCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 9119.AA CRK7 11-294 34 3.7e-101 342.39 In-house 1-343 (343) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-343/343
Sequence Identity: 34% (119 aa)

YEKLNKLGEGTYGVVYKAREKTTKELYALKKIRLESE---DEGIPSTAIREISLLKELQHPNVVRLHDVIHS--------NKK--LVLVFEFVDQDLKKF
||...  |||||| ||||. | |.|. ||||.|.. |    || | |||||| .|..|.|.|.|.|.... .        ..|    .||| .| ||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

MNNFKDKGLDPHIIKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECILKLADFGLARASGIPV--KNYTHEVVTLWYRPPDVLLGSKHY--------
. .   .   .  .|... ||| |.. |||...||||.|  |.|.    ..|.|||||||        . ||  |.|||||||  ||| ..|        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------STSIDIWSIGCIFAEMVNLKPLFPGNSETDELKRIFKLTGTPCVEKWPGLADLPNWKADAFEK-YPGEPL
                               ..||.|| |||..|  . ||.|.|| | . |  |.|. |.|... || . .|| |..    . |    .
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRLR

QNICP-----KLDELGLDLLGKMLRCNPQERITAKAGLEHPYF
 .         ...  |||| |||  .|. |.||.  |.|..|
EEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 9119.AA Pkinase 11-294 30 8.6e-96 329.34 Pfam 1-293 (293) Show / Hide 
Range on Protein: 11-294
Range on HMM: 1-293/293
Sequence Identity: 30% (93 aa)

YEKLNKLGEGTYGVVYKAREKTTKELYALKKIRLESEDEGIPSTAIR--EISLLKELQHPNVVRLHDVIHSNKKLVLVFEFVDQDLKKFMNNF------K
|... |.|.|..|.|||...| | ...|.|.|....|... . |..|  ||...|.|.|||.|||.|. ...... .|.|... .|.  |  |      .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

DKGL--DPHIIKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECIL----KLADFGLARAS-GIPVKNYTHEVVTLWYRPPDVLLGSKHYSTSIDIWS
....  ... .|. .||.|.|.| ||...|.||||||.|.||.... .    |..|||||.     .   .|. ..|.||..| |..|...|....|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGCIFAEMVNLKPLFPGN----SETDELKRIFKLTGTPCVEKWPGLADLPNWKADAFEKYPGEPLQNICPKLDELGLDLLGKMLRCNPQERITAKAGLEH
.|||..||.. .|.|||     .  |....|..  |.|  . || . . .. . . . . . . ..   ....| ..|.. ..|. .|..|.||.  |.|
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQH

PYF
|.|
PWF
Kinase 9119.AA Pkinase_Tyr 11-158 29 2e-14 49.5 Pfam 1-160 (270) Show / Hide 
Range on Protein: 11-158
Range on HMM: 1-160/270
Sequence Identity: 29% (49 aa)

YEKLNKLGEGTYGVVYKAREK----TTKELYALKKIRLESEDEGIPSTA------IREISLLKEL-QHPNVVRLHDVIH-SNKK--LVLVFEFVDQ-DLK
 ... ||||| .|.|||.. |     ||   | |...     ||  . .      .||....|.| .|||.|||. |.    .   . .|.|..   ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

KFMNN--FKDKGLDPHIIKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECILKLADFGLARA
..  .    .. |... . .  .|  || |  . ... ||||   | |.... . | .||||||.
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase 9119.AA TyrKc 11-240 20 7e-12 -30.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 11-240
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

YEKLNKLGEGTYGVVYKAREKTTKELYALKKIRLESEDEGIPSTAIREISLLKEL--QHPNVVRLHDVIHSN-------KKLVLVFEFVDQ-DLKKFMNN
 ... ||||| .|.|||.. |   .  | |... ..         .||......|  .|||.|||. |. .        . | .|.|...  |||..  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

FKDKGLDPHIIKSLLYQLLKGIEVCHKNKILHRDLKPQNLLISKECILKLADFGLARASGIP------VKNYT-----HEV--VTLWYRPPDVLLGSKHY
 ..| | .    |  .|  .| |  |.... ||||   | |.... . | .||||.|. .         . |.     ..   . .   .| ..   . .
HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKF

STSIDIWSIGCIFAEMVNL-KPLFPG-----NSETDELKRIFKLTGTPCVEK--------------------WPG-----------LADL
.|  |.|| |    |.  . ..  ||      | .. .... .    |. .                     |               ..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Ribosomal_L13 9119.AA Ribosomal_L13 453-590 32 1.9e-34 125.53 Pfam 1-133 (133) Show / Hide 
Range on Protein: 453-590
Range on HMM: 1-133/133
Sequence Identity: 32% (47 aa)

YHIFDASKMPLGRMCQKIAFFLQGKHRPTFKNCDQVTYDNIIVVNAANIMLTG-KKALLKTVKYH-TGFVGGLKEKSYKFFLT-EKPEQLVNIYIQLVSK
.|..||. ..|||.. |||  |.|||.||.    . . |..||.||  | .|| ||.  |. ..| ||..||||. ..|  .   .||...         
WHVIDAEGHILGRLASKIAKILRGKHKPTYTPH-VDCGDYVIVINAEKIVITGNKKWDQKMYYHHRTGYPGGLKNPTFKGMFHPRHPERIIW--------

VFYCISKMLPK-NLKRRDLLKKVEIYRDFQHE-KQG-LPNVIQV
    .  |||| | ..|...|.. .|..  |. ..   | |. .
--RAVRGMLPKKNKLGRQMMKRLKVYAGSPHPYHAAQKPEVLEI