Gene 9560 (Tetrahymena)

9560

Species: Tetrahymena
Alias: 9560, 206.m00033, 825, TTHERM_01035490, PreTt09560
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDC2

Sequence

Name Sequence Type Origin Length Description Download
9560.AA Protein None 317 None Fasta, JSON
9560.kin_dom Protein Kinase Domain None 282 None Fasta, JSON
9560.NA RNA None 954 None Fasta, JSON

Protein domain

Protein domains of 9560.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 9560.AA CDC2 24-305 66 9.80000000001e-227 704.68 In-house 1-301 (301) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-301/301
Sequence Identity: 66% (200 aa)

YQRTEKIGEGTYGIVYKAIDMQTNDIIALKKIRLEHEDEG--VPSTAIREISLLKEID-HPNVIKLRDLVYGENKLYLIFDYLDHDLKKYLE-LNGG--P
||. |||||||||.|||..|||||.|.||||||||.||||  ||||||||||.|||.. |||..||.| ..  ||||..|.|||.|||||.. ...   .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LPPAVVKDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSVQLADFGLARAFGLPLKTYT--HEVVTLWYRPPEILLGQKQYSTPVDIWSIGCIFSEM
.||..||.|..|.. |.. ||..||.|||||||||||.|||....|||||||||| |..|||  |||||||||.||||||.|.||||||.|||||||.||
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---AQKIPLFIGDSEIDQIFKIFRIMGTPSESTWPGVTQLPDFKNTFPRWNPIPLQKQCPN---------ICPKGIDLLTKMLQLDPTKRITAEEALDHP
   ..| |||.|||||||.||||||.|||.|.||||||||||.|||||||.|. |.|.|||         ..|.||||| .|||.|| |||.|.|||.||
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHP

YF
||
YF
Kinase 9560.AA CDK 24-305 53 4.90000000001e-189 610.14 In-house 1-284 (284) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-284/284
Sequence Identity: 53% (170 aa)

YQRTEKIGEGTYGIVYKAIDMQTN-----DIIALKKIRLEH-----EDEGVPSTAIREISLLKEIDHPNVIKLRDLVYGE-----------NKLYLIFDY
|.. |||||||||.||||.|.||.     .|.||||||.|.     |.||.|.|||||||||||. |||..||.| ....           ||||..|.|
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

LDHDLKKYLELNGGPLPPAVVKDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGS-----VQLADFGLARAFGL------PLKTYTHEVVTLWYRPPE
.|||||||..          .| |..||. |.. || |.|.||||||||||||..|.     . .||||||||||       |..||||||||||||.||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

ILLGQKQYS--TPVDIWSIGCIFSEMAQ---KIPLFIGDSEIDQIFKIFRIMGTPSESTWPGVTQLPDFKNTFPRWNPIPLQKQCPNICPKGIDLLTKML
.|||.|.||  ||.|.||.||||.||..   . ||| |||||||.||||||.|||.|..|||||.|||.                        ||| |||
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------DLLNKML

QLDPTKRITAEEALDHPYF
..||.|||.||.||.||||
CYDPKKRISAEQALQHPYF
Kinase 9560.AA CDK5 24-305 54 3.3e-174 555.32 In-house 1-287 (287) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-287/287
Sequence Identity: 54% (157 aa)

YQRTEKIGEGTYGIVYKAIDMQTNDIIALKKIRLEHEDEGVPSTAIREISLLKEIDHPNVIKLRDLVYGENKLYLIFDYLDHDLKKYLELNGGPLPPAVV
|.. |||||||||.|||| . .|  |.|||..||. |||||||||||||.||||. |.|.. | | .  |.|| |.| ..| |||||..  .| . ....
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSVQLADFGLARAFGLPLKTYTHEVVTLWYRPPEILLGQKQYSTPVDIWSIGCIFSEMA-QKIPLF
| ...||  |.|.||.... |||||||| ||||.|   ||||||||||| | ..|.||||||||||| .|.| |.|||..|.||.|||| |||    |||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

IGDSEIDQIFKIFRIMGTPSESTWPGVTQLPDFK---NTFPRWNPIP-LQKQCPNICPKGIDLLTKMLQLDPTKRITAEEALDHPYF
 | .. || ..||.|||||.|..||..|.|||.|   . .| ... . .|. .|.   || ||| ||||..| .||.|..|| ||||
PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 9560.AA CMGC 24-305 29 1.1e-152 505.71 In-house 1-513 (513) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-513/513
Sequence Identity: 29% (151 aa)

YQRTEKIGEGTYGIVYKAID--------------MQTNDIIALKKIRLEH---------EDEGVPSTAIREISLLKEI-----------------DHPNV
|.  .||||||||.|||..|              ..|| |.|.|||....         | .|.|..|.|||..||..                 .|.|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

IKLRDLVYGEN-----------------KLYLIFDYLDHDLKKYLELNGG--------PLPPAV------------VKDYL------FQLILGIA--VCH
.||.| .| .|                 .|||.|.|.||||..|.. | .        ||.. .            .| ..      .|.. |..   ||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

ANR--IVHRDLKPQNILINKK--------------------GSVQLADFGLARAFGLP---------------------LKTYTHEVVTLWYRPPEILLG
 ..  |.||||||.|||||..                    | . ..||||||... .                     ...|||.|||.|||.||||||
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

QKQYS---------TPVDIWSIGCIFSEMAQK--------IPLFIGDSE-----------IDQIFKIFRIMGTPS---------------ESTWPGVTQL
 |.|.         ||.|.||.|||| || ..         ||| |.||           |||.||||...|||.               | .||....|
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PDFKN--------------T------------FPRWNPIPLQKQCPN-----------------------------------ICPKGIDLLTKMLQLDPT
|....              .            ||.|.|.|.....|.                                   ..|..|||| ||||.||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRITAEEALDHPYF
||||||.||.||||
KRITAEQALQHPYF
Kinase 9560.AA CDK7 24-305 41 2.7e-143 384.68 In-house 1-288 (288) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-288/288
Sequence Identity: 41% (121 aa)

YQRTEKIGEGTYGIVYKAIDMQTNDIIALKKIR----LEHEDEGVPSTAIREISLLKEIDHPNVIKLRDLVYGENKLYLIFDYLDHDLKKYLELNGGPLP
|.  ..||||... |||| | ||. |.| |||.     .  . |.  |||||| .|.|. |.||| |.|       ..|.||..| ||    . .   | 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

PAVVKDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSVQLADFGLARAFGLPLKTYTHEVVTLWYRPPEILLGQKQYSTPVDIWSIGCIFSEMAQKI
|| .| |  .. .|.  ||.| | |||||| | |.|. | . .|||||||..| | . ||| ||| ||| || | | ..| | ||.||.|||| |    .
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

PLFIGDSEIDQIFKIFRIMGTPSESTWPGVTQLPDFKNTFPRWNP---IPLQKQCPNICPKGIDLLTKMLQLDPTKRITAEEALDHPYF
| . |||.|||. .||...|||.|..||......|. ..|  . .   .||..         .||. .|. ..| ||.|. ..| .|||
PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDY-IKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 9560.AA PITSLRE 24-305 47 1.9e-128 433.01 In-house 1-295 (295) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-295/295
Sequence Identity: 47% (141 aa)

YQRTEKIGEGTYGIVYKAIDMQTNDIIALKKIRLE--HEDEGVPSTAIREIS-LLKEIDHPNVIKLRDLVYGEN--KLYLIFDYLDHDLKKYLELNG---
.|   .|.|||||.||.| | .|..|.|||.. .|   | || | |..|||. .|... |||.....  | | |  | |....|..||||  .|      
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

GPLPPAVVKDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSVQLADFGLARAFGLPLKTYTHEVVTLWYRPPEILLGQKQYSTPVDIWSIGCIFSEM
 |  |  .|  . || .|..  | | | |||||  |.|.. ||   ..|||||| .| |.| ||  ||||||| ||.|||.| ||||||.||.|||| |.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

AQKIPLFIGDSEIDQIFKIFRIMGTPSESTWPGVTQLPDFKN-T-FPRWNPIPLQKQCP---NICPKGIDLLTKMLQLDPTKRITAEEALDHPYF
 .. ||| |.|||||| .||  ||||.|. |||.| || .|. . ||   .  | |  |    |   | ||| .|| ..|..||||..||.||.|
ITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase 9560.AA PCTAIRE 24-305 50 1.3e-125 423.61 In-house 1-291 (291) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-291/291
Sequence Identity: 50% (146 aa)

YQRTEKIGEGTYGIVYKAIDMQTNDIIALKKIRLEHEDEGVPSTAIREISLLKEIDHPNVIKLRDLVYGENKLYLIFDYLDHDLKKYLELNGGPLPPAVV
| . .| |||||  |||     |. ..||| |||||| || | |||||.||||.  | |.. | |... .  | |.| |.| |||.|.. .|  .    |
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHTHHQLTLVFEYMDMDLKQYMDDCGNIMNMHNV

KDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSVQLADFGLARAFGLPLKTYTHEVVTLWYRPPEILLGQKQYSTPVDIWSIGCIFSEMAQKIPLFI
| .||||  | | ||  .| |||||||| ||| .|   |||||||||   | ||| |||||||||||..|.|  .|||..|.| .|||| ||.   ||| 
KLFLFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMCTGRPLFP

GDS------EIDQIFKIFRIMGTPSESTWPGVTQLPDFKN-TFPRWNPIPLQKQCPNIC---PKGIDLLTKMLQLDPTKRITAEEALDHPYF
|          ||   ||||.|||.| |||||. ...|..  |||. . ||    | .     ...||||..||. . .|. ||.|. ||||
GSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF
Kinase 9560.AA PFTAIRE 24-305 48 2.1e-124 419.59 In-house 1-287 (287) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-287/287
Sequence Identity: 48% (140 aa)

YQRTEKIGEGTYGIVYKAIDMQTNDIIALKKIRLEHEDEGVPSTAIREISLLKEIDHPNVIKLRDLVYGENKLYLIFDYLDHDLKKYLELNGGPLPPAVV
|.. || |||.|  |||.|   .. ..||| |||. ..||.| ||||| ||||.  | |.. | | .  .  | ..| |.. ||..|..   | . |  |
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ-QEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPGGMHPNNV

KDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSVQLADFGLARAFGLPLKTYTHEVVTLWYRPPEILLGQKQYSTPVDIWSIGCIFSEMAQKIPLFI
. .||||. | . ||  |. |||||||| || ..|   |||||||||   | .|| ||||||||||| .|||   ||| .|.| .|||| || .  |.| 
RLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAFP

GD-SEIDQIFKIFRIMGTPSESTWPGVTQLPDFKNTFPR---WNPIPLQKQCPNIC--PKGIDLLTKMLQLDPTKRITAEEALDHPYF
|     ||  |||...||| | |||||..|| .|    |    .| .|..| | |   |.. ||..||||. | .|. |.||. ||||
GMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase 9560.AA CRK7 24-305 36 3.6e-108 365.67 In-house 1-343 (343) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-343/343
Sequence Identity: 36% (124 aa)

YQRTEKIGEGTYGIVYKAIDMQTNDIIALKKIRLEHE---DEGVPSTAIREISLLKEIDHPNVIKLRDLVYG--------ENK--LYLIFDYLDHDLKKY
|.. . ||||||| |||| . .|....||||.|...|    || | |||||| .|.. .|.|...|.. |          . |   |..|.| ||||   
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LELNG--GPLPPAVVKDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSVQLADFGLARAFGLPL--KTYTHEVVTLWYRPPEILLGQKQY-------
|| ..      .  .| .. || .|.. || . . |||.|  |||.| .| | .||||||| .      . ||  |.|||||||| ||| ..|       
LE-SKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILK

-------------------------------STPVDIWSIGCIFSEMAQKIPLFIGDSEIDQIFKIFRIMGTPSESTWPGVTQLPDFKNTFPRW------
                                . .|.|| |||. | . | |.| |  |..|. ||..|.|.|    || |..|| ..   |.       
ELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRL

-NPIPLQKQCPNICPKGIDLLTKMLQLDPTKRITAEEALDHPYF
 .    .|.  .. ..  ||| ||| |||.||.||||.|.|..|
REEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 9560.AA Pkinase 24-305 33 2.1e-107 367.95 Pfam 1-293 (293) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-293/293
Sequence Identity: 33% (102 aa)

YQRTEKIGEGTYGIVYKAIDMQTNDIIALKKIRLEHEDEGVPSTAIR--EISLLKEIDHPNVIKLRDLVYGENKLYLIFDYLDH-----DLKKYLE-LNG
|.. .|||.|..| |||...  |..| |.|.|...||..... |..|  ||...|...|||...|.| .. ....|....|...     ||. |..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPL--PPAVVKDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSV----QLADFGLARAF-GLPLKTYTHEVVTLWYRPPEILLGQKQYSTPVDIWSI
|..  .. ..|.|. |.. |.. ||...|.||||||.||||...| .     ..|||||. |   .   .|. ..|.||..||...|.. |...||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCIFSEMAQKIPLFIGD----SEIDQIFKIFRIMGTPSESTWPGVTQLPDFKNTFPRWNPIPLQKQCPNICPKGIDLLTKMLQLDPTKRITAEEALDHPY
|||. ||. . |.| |.    . .||...|.||||.| .. ||     ..|. ... | .. ...  .|. . ..|.....|..||.||.|||..| ||.
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F
Kinase 9560.AA CDK4 24-305 46 6.5e-107 361.5 In-house 1-290 (290) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-290/290
Sequence Identity: 46% (136 aa)

YQRTEKIGEGTYGIVYKAIDMQTNDIIALKKIRLEHEDE--GVPSTAIREISLLK---EIDHPNVIKLRDL-----VYG-ENKLYLIFDYLDHDLKKYLE
||    |||| ||.||.| |..|  ..|||..|   ..|  |.|   |||||...     .|||..|| |      . . | |. ..|   | ||. ||.
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD

LNGGP-LPPAVVKDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSVQLADFGLARAFGLPLKTYTHEVVTLWYRPPEILLGQKQYSTPVDIWSIGCI
    | .||  .|.  .||. |.   |..||.||||||||||..  | | |||||||| ..   .  |  ||||||| ||.|| |  | ||||.||.|||
KCPPPGMPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFGLARIYSFQMA-LTPVVVTLWYRAPEVLL-QSYYNTPVDMWSVGCI

FSEMAQKIPLFIGDSEIDQIFKIFRIMGTPSESTWPGVTQLPDFKNTFPRWNPIPLQKQCPNICPKGIDLLTKMLQLDPTKRITAEEALDHPYF
|.||    ||| | || ||  ||| .||.| |  ||    ||     ||   | |... || .|  |.||| |||  .. ||..|...| ||||
FAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLP--WDHFPQRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase 9560.AA S_TKc 24-305 30 7.1e-102 345.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-231/231
Sequence Identity: 30% (92 aa)

YQRTEKIGEGTYGIVYKAIDMQTNDIIALKKIRLEHEDEGVPSTAIREISLLKEIDHPNVIKLRDLVYGENKLYLIFDYLDH---DLKKYLELNGGP---
|.  .|||.|..| |||...  |. | |.|.|.          ...|||..||. .|||..|| |  .  ..||....|.|.   ||..|.. .|..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LPPAVVKDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSVQLADFGLARAFGLPLKTYTHEVVTLWYRPPEILLGQKQYST-PVDIWSIGCIFSE
  .|. ... |. |...... || ..|.||||||.|||...   . ..|||||| .       |. ..|.||..||.|    .|.. ..|.||.|||. |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MAQKIPLFIGDSEIDQIFKIFRIMGTPSESTWPGVTQLPDFKNTFPRWNPIPLQKQCPNICPKGIDLLTKMLQLDPTKRITAEEALD-------HPYF
|.   |.|       |....|...|                                    | ..|.. |.|| ||.||.|| |||        ||.|
MLCGYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 9560.AA Pkinase_Tyr 24-170 26 7.7e-18 61.05 Pfam 1-160 (270) Show / Hide 
Range on Protein: 24-170
Range on HMM: 1-160/270
Sequence Identity: 26% (44 aa)

YQRTEKIGEGTYGIVYKAIDM----QTNDIIALKKIRLEHEDEGVPSTA------IREISLLKEI-DHPNVIKLRDLVY-GENK--LYLIFDYLDH-DLK
 .  .|.||| .| |||..      .|.   | |...     ||  . .      .||....|.. .|||...|   ..  .    .|... |  | ||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

KYLELN---GGPLPPAVVKDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSVQLADFGLARA
.||  .   ..||..    .. .|   | .  ......||||   |.|..... |  .||||||.
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase 9560.AA TyrKc 24-305 20 2.7e-14 8.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 24-305
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)

YQRTEKIGEGTYGIVYKAIDMQTNDIIALKKIRLEHEDEGVPSTAIREISLLKEI--DHPNVIKLRDLVYGE-------NKLYLIFDYLDH-DLKKYLEL
 .  .|.||| .|.|||..        | |... ..         .||.......  .|||...|   .  .         |.... | .| |||.||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NGGPLPPAVVKDYLFQLILGIAVCHANRIVHRDLKPQNILINKKGSVQLADFGLARAFGLP------LKTYT-----HEV--VTLWYRPPEILLGQKQYS
... |...   .. .|   | .  | ....||||   |.|..... |  .||||.|. .         ..|.     ..   . .   .|| .   . ..
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

TPVDIWSIGC----IFSEMAQKIPL----FIGDSEIDQIFKIFRIMGTPSE----STWPGVTQLPDFKNTFPRWNPIPLQKQCPNICPKGI-DLLTKMLQ
|  |.|| |     ||.  .|  |     .. ..|. .  |  . |  | .    |                             .||. . .. ..  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------F-VCCPDEMYQIMKQCWH

LDPTKRITAEEALDHPYF
 || .| | .|   | .|
EDPEDRPTFSEI--HECF