Gene 18782 (Tetrahymena)
18782
Group:
Other
Family:
Ciliate-A5
Sequence
Protein domains of 18782.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 18782.AA | Ciliate-A5 | 32-318 | 37 | 3.1e-127 | 429.0 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 32-318
Range on HMM: 1-275/275
Sequence Identity: 37% (113 aa)
RYGDQVKIYKQLDSAQRVAIIQKVFDTQMQYQVTVDIQKSLSKLKHPGLIQLLNIVTKKKEQLCSQFFKVKFLYEYVDNDLQKDLEQRRQLEKDLKSIPQ
.|| .||.| . .. .|| .. . ...|.||....|....|.|||..||||.||...|||.||.|......|.|..||
FYG-CMKIWKNQHQQEYYICKQKQIQDEDRQKHFQQYFEQRMQLQHPNIVKLIDFHTHKKEEFCSQFYKVNCYYEYHDNNLEQEMQMRKQCQKD------
NFLTSIEDLKVSNSTYKIFYEESELWYIMATVIAVLSYLKERNLIHGDIRPFNLCLTKDNALKVMTIN----SFIQTNWSSYMEKLEKLDTQS-TYISPI
|||.|.||||||...|.|..||...|..||||||.|.|||.|...|.|..| .|.|.|||||........|.. .|.||.
-----------------IFYNEQELWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQDGQVKLMDMNESKDFFYQINWSSYKQYQHHMSTENKQYLSPM
QLGALQHN----IQRPVHNIPKSDLFCLGVIILELCLLESA-QDIYDFTTFSIDLSARVKKLRDLKK--YSEAFIDFLLQLLVLNEEKRKNPEDLYQIL
|.....|. ||||.||..|||.||||.|.||.|..... |..||..||.|. ....|.|...|. |||.||.|..|.|...|.||......||.|
QWYQMMHRDEQNIQRPEHNWYKSDVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKEKKYSEQFINFIKQMLQFEENKRPDFHQIYQYL
|
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| Kinase | 18782.AA | Ciliate-E4 | 74-121 | 31 | 3.1e-13 | 40.85 | In-house | 52-99 (150) | Show / Hide |
Range on Protein: 74-121 Range on HMM: 52-99/150 Sequence Identity: 31% (15 aa) KLKHPGLIQLLNIVTKKKEQLCSQFFKVKFLYEYVDNDLQKDLEQRRQ .|.|. .|... .. || .|.|| . .. ..||. ||| .. |..| DLNHENIIMVYEYFHKKEDQFCSSIYRLYWFMEYLQKDLQQHIKQHKQ |
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| Kinase | 18782.AA | Ciliate-E4 | 153-197 | 33 | 3.7e-07 | 20.45 | In-house | 106-150 (150) | Show / Hide |
Range on Protein: 153-197 Range on HMM: 106-150/150 Sequence Identity: 33% (15 aa) ESELWYIMATVIAVLSYLKERNLIHGDIRPFNLCLTKDNALKVMT |||.| | | ..|| |. |||..| | .. |.. ESEIWQIAFCCINAMYYLQQVNITHGDLKPSNIFFDQYFMVKIAD |
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| Kinase | 18782.AA | S_TKc | 36-317 | 15 | 5.8e-07 | -74.77 | SMART | 14-231 (231) | Show / Hide |
Range on Protein: 36-317
Range on HMM: 14-231/231
Sequence Identity: 15% (46 aa)
QVKIYKQLDSAQRVAIIQKVFDTQMQYQVTVDIQKSLSKLKHPGLIQLLNIVTKKKEQLCSQFFKVKFLYEYVDN---DLQKDLEQRRQLEKDLKSIPQN
.|. . .. ..||| |. . . . ..| |. .|| ...|. . .. . ||.|. || . ...|. .. .
KVYKCRHKKTGRIVAI--KIIK--EHIRREIQILKK----HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP-----
FLTSIEDLKVSNSTYKIFYEESELWYIMATVIAVLSYLKERNLIHGDIRPFNLCLTKDNALKVM-----TINSFIQTNWSSYMEKLEKLDTQST--YISP
. | . ...|. .. | |. ... || |. | |. |.. .|. .. | |..|
------------------FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAP
IQLGALQHNIQRPVHNIPKSDLFCLGVIILELCLLESAQDIYDFTTFSIDLSARVKKLRDLKKYSEAFIDFLLQLLVLNEEKRKNPEDLYQ---------
| .. .|.| .|.|. |.. . . .. . ||.. |. ..||. ..|. . ||| .. |
EVL----------GYGKCKCDWWSCGCILYEMLCGYPPFP---------QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP
-I
.
WF
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| Kinase | 18782.AA | Ciliate-E1 | 151-248 | 18 | 4.2e-05 | 13.08 | In-house | 106-202 (202) | Show / Hide |
Range on Protein: 151-248 Range on HMM: 106-202/202 Sequence Identity: 18% (18 aa) YEESELWYIMATVIAVLSYLKERNLIHGDIRPFNLCLTKDNALKVMTINSFIQTNWSSYMEKLEKLDTQSTYISPIQLGALQHNIQRPVHNIPKSDLF . . .. .|. | |..|. |.||.|| |.|. .... .. . . . ... .. .| |.. | .. .| . ... |||.. FTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKINYKSDIY |
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| Kinase | 18782.AA | Ciliate-C3 | 169-198 | 33 | 0.000203 | 12.2 | In-house | 111-140 (140) | Show / Hide |
Range on Protein: 169-198 Range on HMM: 111-140/140 Sequence Identity: 33% (10 aa) YLKERNLIHGDIRPFNLCLTKDNALKVMTI || | |..||||.. |. . . .|.. YLHEHNIVHGDIKFSNILINSKDEIKIIDF |
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| Kinase | 18782.AA | Ciliate-E2 | 244-316 | 16 | 0.000217 | 10.96 | In-house | 276-361 (365) | Show / Hide |
Range on Protein: 244-316 Range on HMM: 276-361/365 Sequence Identity: 16% (16 aa) KSDLFCLGVIILELCLLESAQDIYDFTTFSIDLSARVKKLR----------------------DLKKYSEAFIDFLLQ----LLVLNEEKRKN-PEDLYQ |.|...||||. |.. . ... . || |. .|.. . .|. ..||| . .|.. . KCDIWSLGVILYEMLFGKPPF--------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN |
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| Kinase | 18782.AA | Ciliate-E3 | 245-258 | 35 | 0.000428 | 9.0 | In-house | 189-202 (202) | Show / Hide |
Range on Protein: 245-258 Range on HMM: 189-202/202 Sequence Identity: 35% (5 aa) SDLFCLGVIILELC ||. .|.....|| SDYYSVGAVFCQLC |
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| Kinase | 18782.AA | STE | 287-317 | 27 | 0.000462 | 10.38 | In-house | 324-359 (359) | Show / Hide |
Range on Protein: 287-317 Range on HMM: 324-359/359 Sequence Identity: 27% (10 aa) KKYSEAFIDFLLQLLVLNEEKRKNPEDLYQ-----I .|.|. |.||. . |. . .|| ....| . | HKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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| Kinase | 18782.AA | ULK | 287-317 | 22 | 0.000897 | 9.34 | In-house | 291-321 (324) | Show / Hide |
Range on Protein: 287-317 Range on HMM: 291-321/324 Sequence Identity: 22% (7 aa) KKYSEAFIDFLLQLLVLNEEKRKNPEDLYQI .| |. ..|.. ..|. .|..| . |..... PKISPECKDLIRRMLQYDEKDRISWEEIFNH |
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| Kinase | 18782.AA | ULK | 287-317 | 22 | 0.000905 | 9.14 | In-house | 296-326 (329) | Show / Hide |
Range on Protein: 287-317 Range on HMM: 296-326/329 Sequence Identity: 22% (7 aa) KKYSEAFIDFLLQLLVLNEEKRKNPEDLYQI .. |. ..|.. ..|. .|..| . |.|... PQISPECKDLIRRMLQYDEKDRISWEELFNH |
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| Kinase | 18782.AA | Ciliate-E2 | 158-182 | 42 | 0.003577 | 6.72 | In-house | 164-189 (365) | Show / Hide |
Range on Protein: 158-182 Range on HMM: 164-189/365 Sequence Identity: 42% (11 aa) YIMATVIAVLSYLKERN-LIHGDIRP ...| .| | ||...| || || | FYIACIILALEYLHSKNNIIHRDIKP |
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| Kinase | 18782.AA | Ciliate-E3 | 172-194 | 42 | 0.035307 | 2.94 | In-house | 121-146 (202) | Show / Hide |
Range on Protein: 172-194 Range on HMM: 121-146/202 Sequence Identity: 42% (11 aa) ERNLIHGDIRPFNLCLTKDN---ALK |.|.||.|| | | . | | .| EKNIIHSDIKPDNILVDKNNNQLIIK |
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