Gene 19333 (Tetrahymena)

19333

Species: Tetrahymena
Alias: PreTt19333, 595, 19333, 3691.m00110, TTHERM_00300380, 28.m00292
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-B1

Sequence

Name Sequence Type Origin Length Description Download
19333.AA Protein None 529 None Fasta, JSON
19333.kin_dom Protein Kinase Domain None 251 None Fasta, JSON
19333.NA RNA None 1590 None Fasta, JSON

Protein domain

Protein domains of 19333.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 19333.AA Ciliate-B1 9-260 48 1.8e-155 522.82 In-house 1-290 (290) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-290/290
Sequence Identity: 48% (141 aa)

YKVIQEIGNGSIGKVFLCQFDDTQGNQIQVAVKQISDQTILG--QQNKYLAQELNTIQMLIDQMNNG------NKCDHVLQCYEIFQEQQQYYIVSEFCQ
|.....||.|.|..||..||...|..|..||||.|..||...  |||||..|||..||.||..|||.      ..|||....|...|.||||||..|.|.
YQQNNVIGQGAISQVFYGQFCQNQQCQQEVAVKKITKQTQDNDKQQNKYYQQELEIIQCLIKKMNNNKISCQSSPCDHICNIYDVIQCQQQYYIIMEYCE

LGDLYQYLYRNHQNLSTQNYLDIIIQIAKGIQYLHNINLGHRDLKPENILIR----------YNKGLQLVITDFG--VSSFQ-NMKSTVGTINYMAPEIL
 ||||.|.|..|||......||..|||||||||||.....|||||||||||.          ........|||||  ..... .|.|.||||||||||||
QGDLYNYIYNCHQNFTHDIVLDFCIQIAKGIQYLHKHKICHRDLKPENILIHKKNVPIYYNKQQNHYIFKITDFGISKMQQEYMMQSCVGTINYMAPEIL

KFNQSYDKAVDIWSLGCIMHEIIYNEQLFN--GNTTQQVVN----------QRPFLTDLNQIIQS-----CLSLDASYRPTIQDILNRLD
.|||.|||.|||||.||||.|||.|||||.  |||.|.|.|          |..|.....|.||.     ||..|...|.||..|..|| 
NFNQQYDKKVDIWSFGCIMYEIITNEQLFCSLGNTQQEVANQIRNFQCCDYQCHFQNNIYQEIQQLIQKYCLQPDPENRITIDQIIDRLM
Kinase 19333.AA S_TKc 9-263 25 3.1e-64 220.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-263
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

YKVIQEIGNGSIGKVFLCQFDDTQGNQIQVAVKQISDQTILGQQNKYLAQELNTIQMLIDQMNNGNKCDHVLQCYEIFQEQQQYYIVSEFCQL--GDLYQ
|.....|| |. |||..|.  .    . .||.|.|.         . . .|..  ..         ..... ..|..||. . .|.| |.|    |||..
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK---------EHIRREIQILKK---------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFD

YLYRNHQN-----LSTQNYLDIIIQIAKGIQYLHNINLGHRDLKPENILIRYNKGLQLVITDFGVSSFQNMKSTVGTINYMAPEILKFNQSYDK-AVDIW
|. ..  .     ..      .. ||.....|.|. .  ||||||||||.      .. |.|||.. .   .. .|| .|||||.|    .|.| ..|.|
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL--TTFCGTPWYMAPEVL----GYGKCKCDWW

SLGCIMHEIIYNEQLFNGNTTQQVVNQRPFLTDLNQIIQSCLSLDASYRPTIQDILN-----RLDELY
|.|||. | .. . .|   . |.. ..     .. ..|. ||  | . |||. ..|.     ....  
SCGCILYEMLCGYPPFP--QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 19333.AA Pkinase 9-259 26 1.4e-58 205.77 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-259
Range on HMM: 1-293/293
Sequence Identity: 26% (80 aa)

YKVIQEIGNGSIGKVFLCQFDDTQGNQIQVAVKQISDQTILGQQNKYLAQ--ELNTIQMLIDQMNNGNKCDHVLQCYEIFQEQQQYYIVSEFCQLG----
|.... || || |.|..|.  .|.    .||||.|. ...  .......   |.   ..| .       .......|..|.. . .|.| |.|. |    
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N-------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVM

DLYQYLY-RNHQNL--STQNYLDIIIQIAKGIQYLHNINLGHRDLKPENILIRYNKGL--QLVITDFGVSSF-----QNMKSTVGTINYMAPEILKFNQS
||. |.  ..| ..  | .   ... ||..|..|.|. .  |||||||||||  |  .   . |.|||.. .     . |.. .||..|||||.....| 
DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQY

YDKAVDIWSLGCIMHEIIYNEQLFNGN-----TTQQVVNQRPFL-------------------------------TDLNQIIQSCLSLDASYRPTIQDIL
|...||.||.|||..| .  . .| |       .|... .|                                   .. ..| .|| .| . |||...||
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

NR--L
.   .
QHPWF
Kinase 19333.AA Ciliate-E2 9-257 22 1.3e-55 189.35 In-house 1-361 (365) Show / Hide 
Range on Protein: 9-257
Range on HMM: 1-361/365
Sequence Identity: 22% (84 aa)

YKVIQEIGNGSIGKVFLCQFDDTQGNQI---------------QVAVKQISDQTILGQQNKYLAQELNTIQMLID---QMNN------GNKCDHVLQCYE
||.|. ||.|. |.|..|. . .| ...               .|..|..   ..  .| ... ||.. .. . .   .  |       .........||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMYE

IFQ--EQQQYYIVSEFCQLGDLYQYLY-----RNHQ-----NLSTQNYLDIIIQIAK---------------GIQYLHNIN-LGHRDLKPENILIRYNKG
 ||   .. .|.| |.|| |||..|..     |||.     ... .  ..|. ||..               ...|||. |   |||.||||||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LQLVITDFGVSSFQN------------------------------------MKSTVGTINYMAPEILKFNQS--------YDKAVDIWSLGCIMHEIIYN
  . |.||| | ...                                     ....|| .|||||||.  .         ||...||||||.|..| ...
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

EQLFNGNTTQQVVNQRPFLTDLN------------------------QIIQS----CLSLDASYRPT-IQDILN
.  |     ||   | ..  . .                        ..|.     .|  | . |.| ...|||
KPPF-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 19333.AA Ciliate-E2a 9-227 29 3.6e-55 160.87 In-house 1-227 (275) Show / Hide 
Range on Protein: 9-227
Range on HMM: 1-227/275
Sequence Identity: 29% (70 aa)

YKVIQEIGNGSIGKVFLCQFDDTQGNQIQVAVKQISDQTILGQQNKYLAQELNTIQMLIDQMNNGNKCDHVLQCYEIFQEQQQYYIVSEFCQLGDLYQYL
||.| .||.|. |.|.| |  .|  ..  ...| |    . .....|. .|.| ...|        . ..... ||...  ..||.| |.|. |.||...
YKFIKKIGKGNFGSVYLAQHKQT--GKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQL--------DHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKI

YRNHQNLST-QNYLDIIIQIA-KGIQYLHNINLGHRDLKPENILIR---YNKG--LQLVITDFGVSSFQ----N--MKSTVGTINYMAPEILKFNQ----
  .... .  |.  ||. |.  .|..|.|. |  ||||||||||..    |.   ....| ||| . |.    .  |.. .||  |.|||.|.  .    
KQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKH

-SYDKAVDIWSLGCIMHEIIYNEQLFNGNTTQQVVNQ
 .||. .|.||.|.|..  .. ...|.| |..... |
KQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQ
Kinase 19333.AA Ciliate-E2-Unclassified 9-257 23 2.4e-52 179.88 In-house 1-348 (352) Show / Hide 
Range on Protein: 9-257
Range on HMM: 1-348/352
Sequence Identity: 23% (83 aa)

YKVIQEIGNGSIGKVFLCQFDDTQGNQIQVAVKQISDQTILGQQNK-------YLAQELNTIQMLIDQMN----------NGNKCDHVLQCYEIFQEQQQ
||.|. ||.|. |||..|| ...  .  . | |..... |  |...         ..|.| ...  ....            ... ... ....|| .| 
YKIIKQIGQGGFGKVYKCQHKKQ--K-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK--YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN

YYIVSEFCQLGDLYQYLYRNHQ----------------NLSTQNYL-----DIIIQIAKGIQYLHNIN-LGHRDLKPENILIRYNKG-LQLVITDFGVSS
 ||| |.|. ||| ||.  ...                 .. |. .     ... || .|..|||  |   |||.||||||.  |.. ... |.||| |.
IYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISK

--------------------FQNMKSTVGTINYM----APEILKFNQSYD---KAVDIWSLGCIMHEIIYNEQLFNGNT-------------------TQ
                    .|.|....||.|||    |||.|. .. ..   ...||||||.|..|.....  |..|.                    .
KYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLY

QVVNQRPFL----------TDLN--------QIIQSCLSLDASYRPTIQDILN
|  .|...            ...        ...|..|  . ..|.|...|||
QNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 19333.AA TKL 15-259 18 5.3e-51 175.75 In-house 1-364 (364) Show / Hide 
Range on Protein: 15-259
Range on HMM: 1-364/364
Sequence Identity: 18% (69 aa)

IGNGSIGKVFLCQFDDTQGNQ------IQVAVKQISDQT----------------------ILGQQNKYLAQELNTIQMLIDQMNNGNKCDHVLQCYEIF
|| |. |.|.  ..  . | .        ||||... .                       .   . ..  .| . | |..       ......|.. . 
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRL-----RHPNIVQFMGYC

QEQQQ-------------YYIVSEFCQLGDLYQYLYRNHQNLSTQNYLDIIIQIAKGIQYLHNIN--------LGHRDLKPENILIRYN-----------
.. ..             ..|| |.|. |.|. ||         .  ......||.|..|||. |        . |||||..|||.  |           
CCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNP

-KGLQLVITDFGVSSFQNMKS------------------------TVGTINYMAPEILKFNQ---------------SYDKAVDIWSLGCIMHEIIYNEQ
 .   . |.||| | | ....                         .||...||||.|. ..               .|....|..| | .. ||.  ..
NADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR

LFNGNTTQQVV---------------NQRPFLT-----------------DLNQIIQSCLSLDASYRPTIQDILNRL
 . ..   ...               ..|| .                  .. ...| | . |.. ||. |.|| ||
PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 19333.AA CAMK 14-257 17 5.5e-51 162.13 In-house 1-421 (425) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-421/425
Sequence Identity: 17% (73 aa)

EIGNGSIGKVFLCQFDDTQGNQ---------IQVAVKQ-------------------ISDQTILGQQNKYLAQELNTIQMLIDQMNNGNK------CDHV
..| || |||.||.   |.|..          .||.|                    |....  .....  .. .  ..  |. |.. ..        ..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LQCYEIFQE-------------------QQQYYIVS---EFCQLG----DLYQYLYRNHQN--------------LSTQNYLDIIIQIAKGIQYLHNINL
...||...                    ....|.|    |.|. |    ||..|. .. ..              .. .    .. ||. ...|.|. | 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

GHRDLKPENILIRYNKG---------------LQLVITDFGVSSFQN----------------------------MKSTVGTINYMA-PEILKF------
 ||||||||||. .|..                .. |.||| . . .                            ||  .||  ||| ||.|.       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------NQSYDKAVDIWSLGCIMHEIIYNEQLFNGNTTQ-----------------QVVNQR-PFL----------------------------TDLNQ
       .. |....|.||.|.|.      .  |.| . .                 .. . .  |                             ..  .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IIQSCLSLDASYRPTIQDILN
 |...|  | . |.||...||
LIRKMLQVDPEKRMTIEQCLN
Kinase 19333.AA ULK 9-213 29 3.9e-46 159.07 In-house 1-253 (329) Show / Hide 
Range on Protein: 9-213
Range on HMM: 1-253/329
Sequence Identity: 29% (75 aa)

YKVIQEIGNGSIGKVFLCQFDDTQGN--QIQVAVKQISDQTILGQQNK--------YLAQELNTIQMLIDQMNNGNKCDHVLQCYEIFQEQ--QQYYIVS
| .....| || |||.     .|.    ...||.|.|. |..  ..|          | .|  ....| .. .. |.. .. . |..|...    .||. 
YCLNHCLGKGSFGKVYKGRNKKTK-DYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIM

EFCQLGDLYQYLYRNHQ---------NLSTQNYLDIIIQIAKGIQYLHNINLGHRDLKPENILIRYNKGL----------QLVITDFGVSSF-Q-N----
|.|. ||| ||. .|.          .|| |  . ...||. | ..||  |  |||.||.||||  ...           .| |.||| . . . .    
EYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

--MKSTV------GTINYMAPEILK----FNQSYDKAVDIWSLGCIMHEIIYNE
  |...|      ||  ||||.||.      . ||. .||||||||..|..|..
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGK
Kinase 19333.AA ULK 9-213 28 3.1e-45 156.6 In-house 1-249 (324) Show / Hide 
Range on Protein: 9-213
Range on HMM: 1-249/324
Sequence Identity: 28% (73 aa)

YKVIQEIGNGSIG-KVFLCQFDDTQGN-QIQVAVKQISDQTILGQQNK--------YLAQELNTIQMLI--DQMNNGNKCDHVLQCYEIFQEQ--QQYYI
| .....| || | ||.   ..  ... . .||.|.|. . .  ..|.         | .| .....|      |    . |. . |..|...    .||
YCLNHCLGKGSFGVKVY-KGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPN----H-HIVKLYDWFETSNHNNIYI

VSEFCQLGDLYQYLYRNHQ--------NLSTQNYLDIIIQIAKGIQYLHNINLGHRDLKPENILIRYNKGL----------QLVITDFGVSSF-------
. |.|. ||| ||. .|.         .|| |  . ...||. | ..||. |  |||.||.||||  ...           .| |.||| . .       
IMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNME

-QNMKSTV------GTINYMAPEILK---FNQSYD-KAVDIWSLGCIMHEIIYNE
 | ....|      ||  ||||.||.    .. |. . .||||||||..|..|..
QQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGK
Kinase 19333.AA CMGC 9-220 20 4.5e-41 132.11 In-house 1-347 (513) Show / Hide 
Range on Protein: 9-220
Range on HMM: 1-347/513
Sequence Identity: 20% (72 aa)

YKVIQEIGNGSIGKVFLCQFDDTQGN-----------QIQVAVKQISDQTILGQQNK----------YLAQELNTIQMLIDQMNNGN----------KCD
|..|. || |. |.|. |.  .|...           . .||.| |. .     | |              |.   ..| .. .. |          .  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

HVLQCYEIFQEQQ-----------------QYYIVSEFCQLGDLYQYLYRNH---------------------------QNLSTQNYLDIIIQIAKGIQ-
.....|.||.  .                 . |.| |...  |||||...|.                           ....  .   .. || .|.  
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKL

-YLHNIN--LGHRDLKPENILIRYN------------------KGLQLVITDFGVSSFQN--------------------------MKSTVGTINYMAPE
 |.|  .    |||||||||||  |                  |  .| | ||| . . .                          . . | |  | |||
KYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPE

ILKFNQS----------YDKAVDIWSLGCIMHEIIYN--------EQLFNGNT
|| .. .          |....|.||.|||. |.. .        . || |..
IL-LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHS
Kinase 19333.AA STE 9-257 18 2e-39 136.91 In-house 1-353 (359) Show / Hide 
Range on Protein: 9-257
Range on HMM: 1-353/359
Sequence Identity: 18% (68 aa)

YKVIQEIGNGSIGKVFLC-QFDDTQGN-----------QIQVAVKQIS----DQTILG-QQNKYLAQ-------ELNTIQMLIDQMNNGNK-CDHVLQCY
.. |..||.|. |.|...   ......           .  .|.||..    .. .   | ..   .       |.. |.. |. |.. |. .... ..|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQ-EN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYY

EIFQEQ-------QQYYIVSEFCQLGDLYQYLYRNH---QNLSTQNY------LDII----IQIAKG-IQYLHNINLGHRDLKPENILIRYNKGLQLVIT
  .          .. .|. |..  | | . . ...   ..|. ..        ..|     || ||  .|||. .  |||.|| |||.         ..
GCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-------VKLC

DFGVSS---------------------FQNMKSTVGTINYMAPEILKF-----NQSYDKAVDIWSLGCIM-------HEI---IYN----EQLFNG----
||||..                      |. .. |||  .||||...      .. ||  .||||||| .       ..     .     . .||.    
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQ

---------NTTQQVVN-----------------QRPFLTDLNQIIQSCLSLDASYRPTIQDILN
         ..  .  .                 .. .  .... |. ||  | . ||| .. |.
QFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLK
Kinase 19333.AA Pkinase_Tyr 75-210 28 8.8e-18 60.84 Pfam 62-208 (270) Show / Hide 
Range on Protein: 75-210
Range on HMM: 62-208/270
Sequence Identity: 28% (43 aa)

KCDHVLQCYEIFQ-EQQQ--YYIVSEFCQLGDLYQYLYRN---HQNLSTQNYLDIIIQIAKGIQYLHNINLGHRDLKPENILIRYNKGLQLVITDFGVSS
........| .   ....  .||| |....|||. || ..    |.|...  |.. .||||| .||...|. ||||   |.|.   ....  |.||| . 
HHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVT--ENNVVKICDFGLAR

FQ----NMKSTVGT-----INYMAPEILKFNQSYDKAVDIWSLGCIMHEII
      .  .....     |  |||| ....  .  . |.|| |  | ||.
DIYNDDYY-YRKRGGGKLPIKWMAPECINYGK-FTTKSDVWSFGVLMWEIF
Kinase 19333.AA TyrKc 9-259 21 1.4e-17 61.57 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-259
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

YKVIQEIGNGSIGKVFLCQFDDTQGNQIQVAVKQISDQTILGQQNKYLAQELNTIQMLIDQMN--NGN--KCDHVLQCYEIFQEQ-------QQYYIVSE
 . ....|.|  |.|.... .      |||||| . . .               ...... ..       . ......| .  .|       ....|| |
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA---------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVME

FCQLGDLYQYLYRNHQNLSTQNYLDIIIQIAKGIQYLHNINLGHRDLKPENILIRYNKGLQLVITDFGVSSFQNMK----------------STV--GTI
.. .||| .|| ... .|...  |.. .|||.| .|||  |. ||||   |.|.  |.  .  |.||| | .   .                ..     |
YMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI

NYMAPEILKFNQSYDKAVDIWSLGCIMHEIIYNEQLFNGN------TTQQVVNQ--------RPFL----------TDLNQIIQSCLSLDASYRPTIQDI
  |||| . .   .  . |.|| |  | ||  . |    .      . |.|...        .|            ... ||...|   |.. ||| ..|
RWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

LNRL
  ..
HECF
Kinase 19333.AA Pkinase_Tyr 9-47 25 0.003906 11.24 Pfam 1-40 (270) Show / Hide 
Range on Protein: 9-47
Range on HMM: 1-40/270
Sequence Identity: 25% (10 aa)

YKVIQEIGNGSIGKVFLCQFD-DTQGNQIQVAVKQISDQT
 . ....| |. |.|...  . | ....|.|||| . ...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGA
Kinase 19333.AA Pkinase_Tyr 233-259 25 0.051034 7.46 Pfam 244-270 (270) Show / Hide 
Range on Protein: 233-259
Range on HMM: 244-270/270
Sequence Identity: 25% (7 aa)

DLNQIIQSCLSLDASYRPTIQDILNRL
.. .....|   |.. ||| ..|...|
EIYDLMKQCWHYDPEDRPTFSEIHEQL