Gene 11408 (Tetrahymena)

11408

Species: Tetrahymena
Alias: 3.m01690, 1064, 3824.m03163, TTHERM_00052280, PreTt11408, 11408
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
11408.AA Protein None 6110 None Fasta, JSON
11408.kin_dom Protein Kinase Domain None 162 None Fasta, JSON
11408.NA RNA None 18333 None Fasta, JSON

Protein domain

Protein domains of 11408.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Efhand 11408.AA efhand 371-399 44 2.5e-07 31.27 Pfam 1-29 (29) Show / Hide 
Range on Protein: 371-399
Range on HMM: 1-29/29
Sequence Identity: 44% (13 aa)

SLKDIFRMLDSDNDSYISKEEFKLAFKKA
 ||..|...| |.| ||..|||. ..|| 
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 371-399 48 2e-06 28.65 SMART 1-29 (29) Show / Hide 
Range on Protein: 371-399
Range on HMM: 1-29/29
Sequence Identity: 48% (14 aa)

SLKDIFRMLDSDNDSYISKEEFKLAFKKA
 .|..|||.| |.| ||..|||| ..|. 
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 407-435 27 0.01173 14.14 Pfam 1-29 (29) Show / Hide 
Range on Protein: 407-435
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

ILDEAYFRFDFNKDDKVSFNEFLNVILGQ
 |.|.   || ..| ...|.||....  .
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 407-435 24 0.028635 8.94 SMART 1-29 (29) Show / Hide 
Range on Protein: 407-435
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

ILDEAYFRFDFNKDDKVSFNEFLNVILGQ
 ..|.   || ..| ...|.||. ..   
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 482-495 28 4.768647 4.59 Pfam 16-29 (29) Show / Hide 
Range on Protein: 482-495
Range on HMM: 16-29/29
Sequence Identity: 28% (4 aa)

KITEDEFCAFVSQF
.|. .|||......
YIDFEEFCEMMKKL
EFh 11408.AA EFh 504-532 27 0.058637 6.43 SMART 1-29 (29) Show / Hide 
Range on Protein: 504-532
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

QMKTVFSYLDRDGKRNLKQEEFLEIYEHQ
..| .|. .|.||   .  |||...    
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 504-532 31 0.082985 11.03 Pfam 1-29 (29) Show / Hide 
Range on Protein: 504-532
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

QMKTVFSYLDRDGKRNLKQEEFLEIYEHQ
..| .|. .|.||   .  |||.|.....
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
Efhand 11408.AA efhand 673-701 31 51.319586 0.81 Pfam 1-29 (29) Show / Hide 
Range on Protein: 673-701
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

TLRDLFNIFSQKQFGYLDQEEFIILINFM
 |...|..| . . ||.| |||. ..  .
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
Efhand 11408.AA efhand 1294-1322 24 0.000378 19.6 Pfam 1-29 (29) Show / Hide 
Range on Protein: 1294-1322
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

DWNDLVEFLDQNNSGFIDKEEFEFLYEMI
..... . .|....|.||.|||  .....
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 1294-1322 24 0.003561 16.24 SMART 1-29 (29) Show / Hide 
Range on Protein: 1294-1322
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

DWNDLVEFLDQNNSGFIDKEEFEFLYEMI
..... . .|....|.||.|||  .  ..
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 1363-1391 34 1.9e-05 24.33 Pfam 1-29 (29) Show / Hide 
Range on Protein: 1363-1391
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

SIEDAFKAFDSDGLGTISCQEFEYILQRV
 ....|| || || |.|. .||  .....
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 1363-1391 31 0.000214 21.85 SMART 1-29 (29) Show / Hide 
Range on Protein: 1363-1391
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

SIEDAFKAFDSDGLGTISCQEFEYILQRV
 ....|. || || |.|. .||  .....
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 1400-1428 31 0.000941 18.15 Pfam 1-29 (29) Show / Hide 
Range on Protein: 1400-1428
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

YSNELIQFIDRDKNGMIDFQEFSLILGIA
  .|... .|.|..| |||.||  ..   
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 1400-1428 31 0.001983 18.29 SMART 1-29 (29) Show / Hide 
Range on Protein: 1400-1428
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

YSNELIQFIDRDKNGMIDFQEFSLILGIA
  .|... .|.|..| |||.||  ..   
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
WD40 11408.AA WD40 1715-1754 21 1.9e-09 29.82 Pfam 1-39 (39) Show / Hide 
Range on Protein: 1715-1754
Range on HMM: 1-39/39
Sequence Identity: 21% (9 aa)

IQPTRVIESAHYDSIISFTYLPY-CQLVASSSADNTIKLWN
 ......  .| ... .  . |  ....||.|.|.||..|.
WKCKHTF--GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD
WD40 11408.AA WD40 1714-1754 18 5.4e-07 30.48 SMART 1-46 (46) Show / Hide 
Range on Protein: 1714-1754
Range on HMM: 1-46/46
Sequence Identity: 18% (9 aa)

VIQPTRVIESAHYD--SIISFTYLPYC------QLVASSSADNTIKLWN
  ....... .| .  .. . .. |        ...||.| |.||..|.
T-KCVHTFK-GHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD
Efhand 11408.AA efhand 2072-2084 38 5.94289 4.24 Pfam 17-29 (29) Show / Hide 
Range on Protein: 2072-2084
Range on HMM: 17-29/29
Sequence Identity: 38% (5 aa)

ISKDDFLQMLHKL
|....|..|..||
IDFEEFCEMMKKL
Efhand 11408.AA efhand 2527-2546 30 34.120105 1.46 Pfam 10-29 (29) Show / Hide 
Range on Protein: 2527-2546
Range on HMM: 10-29/29
Sequence Identity: 30% (6 aa)

DTDKKLEIEISEFCNIIRFT
|.|.  .|.. |||.... .
DKDGDGYIDFEEFCEMMKKL
WD40 11408.AA WD40 2888-2895 37 25.536221 0.66 Pfam 32-39 (39) Show / Hide 
Range on Protein: 2888-2895
Range on HMM: 32-39/39
Sequence Identity: 37% (3 aa)

DNGVSLWD
|. . .||
DGTIRIWD
EFh 11408.AA EFh 2983-3011 44 2.4e-08 34.98 SMART 1-29 (29) Show / Hide 
Range on Protein: 2983-3011
Range on HMM: 1-29/29
Sequence Identity: 44% (13 aa)

SLHRAFNLFDEDGDGVISQQEFVIGMKQL
 . ..|..|| |||| |. .||. .|| |
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 2983-3011 48 1e-07 32.69 Pfam 1-29 (29) Show / Hide 
Range on Protein: 2983-3011
Range on HMM: 1-29/29
Sequence Identity: 48% (14 aa)

SLHRAFNLFDEDGDGVISQQEFVIGMKQL
 | ..|..|| |||| |. .||. .||.|
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 3019-3047 27 1.4e-07 32.38 SMART 1-29 (29) Show / Hide 
Range on Protein: 3019-3047
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

EIKKLMKIIDIDGNEQISKQEFIKVLSEK
|.|......| ||. .|...||.......
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 3019-3047 31 2e-06 28.09 Pfam 1-29 (29) Show / Hide 
Range on Protein: 3019-3047
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

EIKKLMKIIDIDGNEQISKQEFIKVLSEK
|.|...|..| ||. .|...||.......
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 3077-3105 24 0.073895 5.62 SMART 1-29 (29) Show / Hide 
Range on Protein: 3077-3105
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

DLLQAFEEVDTQQRGFIYFKQLKDCLLRF
.. ..|...|.   |.| |. .||.. ..
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 3077-3105 24 0.168938 9.9 Pfam 1-29 (29) Show / Hide 
Range on Protein: 3077-3105
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

DLLQAFEEVDTQQRGFIYFKQLKDCLLRF
.| ..|.|.|. . |.| |. ..... ..
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
Efhand 11408.AA efhand 3237-3265 27 0.001799 17.12 Pfam 1-29 (29) Show / Hide 
Range on Protein: 3237-3265
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

TLFEAFAYFDVNSTNTISQLELRVGLKNM
 | |.|. ||..   .|.  |.. ..|..
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 3237-3265 24 0.002754 17.14 SMART 1-29 (29) Show / Hide 
Range on Protein: 3237-3265
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

TLFEAFAYFDVNSTNTISQLELRVGLKNM
 . |.|. ||..   .|.  |.....|..
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
EFh 11408.AA EFh 3273-3301 27 0.238251 1.52 SMART 1-29 (29) Show / Hide 
Range on Protein: 3273-3301
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

DFDRVFKSFEKTPQGKITFNAFFNRFIEA
.|...|. | |   |.|.|. |   . . 
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 3329-3357 31 1.2e-05 25.07 Pfam 1-29 (29) Show / Hide 
Range on Protein: 3329-3357
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

NFEQAFNKLDINGNGQLSIFEFKESCKRL
 ....|...| .|.|.... ||.| .|.|
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 3329-3357 34 0.000141 22.45 SMART 1-29 (29) Show / Hide 
Range on Protein: 3329-3357
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

NFEQAFNKLDINGNGQLSIFEFKESCKRL
 |...|...| .|.|...  |||. .|.|
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 3595-3623 27 0.004623 15.62 Pfam 1-29 (29) Show / Hide 
Range on Protein: 3595-3623
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

SIKLLFNTIDIDGKEYITLSELNNALADT
 .| .|. .| ||  ||.. |. ......
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 3595-3623 27 0.006268 14.26 SMART 1-29 (29) Show / Hide 
Range on Protein: 3595-3623
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

SIKLLFNTIDIDGKEYITLSELNNALADT
 .| .|. .| ||  ||.. |.  ...  
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 3794-3805 33 12.961387 3.0 Pfam 1-12 (29) Show / Hide 
Range on Protein: 3794-3805
Range on HMM: 1-12/29
Sequence Identity: 33% (4 aa)

EFLKIFQAVDKN
|. ..|. .||.
ELKEMFKEFDKD
Efhand 11408.AA efhand 3907-3929 43 0.000248 20.27 Pfam 7-29 (29) Show / Hide 
Range on Protein: 3907-3929
Range on HMM: 7-29/29
Sequence Identity: 43% (10 aa)

AVFDRNGNGILSREEFLEALKLL
..||..|.| ...|||.|..| |
KEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 3904-3929 34 0.005373 14.8 SMART 1-29 (29) Show / Hide 
Range on Protein: 3904-3929
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

QLKAVF---DRNGNGILSREEFLEALKLL
..|..|   |..|.| .. |||....| |
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 3937-3965 17 4.126371 4.82 Pfam 1-29 (29) Show / Hide 
Range on Protein: 3937-3965
Range on HMM: 1-29/29
Sequence Identity: 17% (5 aa)

KARILLDYIDRDESGRIEIDTFIQDIFES
... . . .|.| .|.|... |.. . . 
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 4115-4143 34 1e-06 29.31 SMART 1-29 (29) Show / Hide 
Range on Protein: 4115-4143
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

NVEEAFKKIDQDSSGLISSSEFRRFIESL
 ..|.|...|.| .| |.  ||.... ||
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 4115-4143 34 2e-06 28.03 Pfam 1-29 (29) Show / Hide 
Range on Protein: 4115-4143
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

NVEEAFKKIDQDSSGLISSSEFRRFIESL
 ..|.||..|.| .| |.  ||......|
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
Efhand 11408.AA efhand 4222-4250 13 2.213727 5.81 Pfam 1-29 (29) Show / Hide 
Range on Protein: 4222-4250
Range on HMM: 1-29/29
Sequence Identity: 13% (4 aa)

KMERAWAILDQRKIGLFEIEDFRHALVQM
.........|. . |  ..|.|.... ..
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
Efhand 11408.AA efhand 4258-4286 31 0.01173 14.14 Pfam 1-29 (29) Show / Hide 
Range on Protein: 4258-4286
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

ELKSAFNFIDTDSDSVVKYLEFVDFWIGG
||| .|. .|.| |  . . ||....   
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 4258-4286 31 0.020502 10.11 SMART 1-29 (29) Show / Hide 
Range on Protein: 4258-4286
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

ELKSAFNFIDTDSDSVVKYLEFVDFWIGG
|.| .|. .|.| |  . . ||.|.    
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 4332-4360 31 0.013387 13.93 Pfam 1-29 (29) Show / Hide 
Range on Protein: 4332-4360
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

SLWDCFKFFDEEQKGYLTKQQFNDFLQKI
 | . || ||  . ||.... | ....|.
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 4332-4360 24 0.029549 8.83 SMART 1-29 (29) Show / Hide 
Range on Protein: 4332-4360
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

SLWDCFKFFDEEQKGYLTKQQFNDFLQKI
 . ..|. ||    ||.... | |.....
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 11408.AA efhand 4434-4462 34 0.000674 18.68 Pfam 1-29 (29) Show / Hide 
Range on Protein: 4434-4462
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

NLEDFFSEYDSDYDGFLTPNEFYNAFKYI
 |...|.|.| | ||... .|| ...| .
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 11408.AA EFh 4434-4462 27 0.006109 14.35 SMART 1-29 (29) Show / Hide 
Range on Protein: 4434-4462
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

NLEDFFSEYDSDYDGFLTPNEFYNAFKYI
 ... |...| | ||.....||  ..| .
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Kinase 11408.AA Ciliate-E2 4872-5033 17 2.5e-14 45.6 In-house 252-365 (365) Show / Hide 
Range on Protein: 4872-5033
Range on HMM: 252-365/365
Sequence Identity: 17% (33 aa)

PYLAPEQILRKTAD-------WNAYSDIWGFGCLLYHILFGQPPKSFYQSLIDRYGDIDKEEFTEPSTFFHYDIYSDELAQEVLRVDYNDNPDSKINLKY
.|.||| . .|  |       ..  .||| .|..||  |||.||                                                        
GYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-------------------------------------------------------

IPPSDIAMVKAIDKSTFGNIFNKIFPTAGKEYER------------EFQQLSEV-LDLISA----CLQYTPSKRPT-VEGLLQSPVF
                   . .|  .    ..|             .....|.   |||.     .||. |.||.|  | .|. | |
------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 11408.AA AGC 4873-4908 36 2.7e-09 18.65 In-house 273-304 (395) Show / Hide 
Range on Protein: 4873-4908
Range on HMM: 273-304/395
Sequence Identity: 36% (14 aa)

YLAPEQILRKTADWNAYSDIWG--FGCLLYHILFGQPP
|.||| .       .   |.|.  .|||.|  |.|.||
YMAPEIL------YGKACDWWSFGLGCLMYEMLTGYPP
Kinase 11408.AA CMGC 5004-5033 46 1.1e-08 23.72 In-house 484-513 (513) Show / Hide 
Range on Protein: 5004-5033
Range on HMM: 484-513/513
Sequence Identity: 46% (14 aa)

SEVLDLISACLQYTPSKRPTVEGLLQSPVF
.. .||.. .||| |.||.|.|  || | |
PQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 11408.AA RCK 5001-5033 33 2e-08 22.51 In-house 266-298 (298) Show / Hide 
Range on Protein: 5001-5033
Range on HMM: 266-298/298
Sequence Identity: 33% (11 aa)

QQLSEVLDLISACLQYTPSKRPTVEGLLQSPVF
.. .. ..|.  .||. |.||.| . .|| | |
NCSQDCIELMEKMLQWDPQKRITAQQALQHPYF
S_TKc 11408.AA S_TKc 4706-5033 14 2.4e-08 -54.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 4706-5033
Range on HMM: 1-231/231
Sequence Identity: 14% (54 aa)

LKLHNNIG------------------VFLKRVGHELGDIEYMVMNEAIDPAEYISLYDLIQ-----------QN--GGLFRIPVLVKLR-----SVTYLL
 .... ||                  | .|..  |    |  .. .  .    . ||| .|            .  | ||.. .  . .           
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-EHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA

KYIARQILQILQAINNEACFLNI----LRPENIFINRHTYEIKLA---NVRGVAKYDLFSKVSMIPDLEFNLVQRVGPLAVVDTQLDYQEYFNAESEFKH
.....||.. |. . .    ..|    | ||||....   .||..     | .                                               
RFYMYQICCALEYCHS----HGIIHRDLKPENILLDE---HIKICDFGLARQL-----------------------------------------------

FYREQLFLQPYLAPEQILRKTADWNA-YSDIWGFGCLLYHILFGQPPKSFYQSLIDRYGDIDKEEFTEPSTFFHYDIYSDELAQEVLRVDYNDNPDSKIN
  . .     |.||| .      ..   .|.| .||.||  | |.|| .     ...  .. .                                     
--TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-------------------------------------

LKYIPPSDIAMVKAIDKSTFGNIFNKIFPTAGKEYEREFQQLSEVLDLISACLQYTPSKRPTVEGLLQ-------SPVF
                                          .|..|.|. |||. |.||||.  .||        | |
-----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 11408.AA Ciliate-E2-Unclassified 4873-4908 39 3e-07 21.24 In-house 232-269 (352) Show / Hide 
Range on Protein: 4873-4908
Range on HMM: 232-269/352
Sequence Identity: 39% (15 aa)

YLAPEQILRKTADWNAY--SDIWGFGCLLYHILFGQPP
|.||| . ..  |  .   .|||..|..|| .|||..|
YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP
Kinase 11408.AA Pkinase 4993-5033 25 5.2e-07 25.86 Pfam 232-293 (293) Show / Hide 
Range on Protein: 4993-5033
Range on HMM: 232-293/293
Sequence Identity: 25% (16 aa)

GKEYEREFQQL---------------------SEVLDLISACLQYTPSKRPTVEGLLQSPVF
|..........                     .| .|.|. ||.. |.|||| | .||.| |
GPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 11408.AA PLK1 4873-4931 40 7.2e-07 18.33 In-house 165-220 (253) Show / Hide 
Range on Protein: 4873-4931
Range on HMM: 165-220/253
Sequence Identity: 40% (24 aa)

YLAPEQILRKTADWNAYSDIWGFGCLLYHILFGQPPKSFYQSLIDRYGDIDKEEFTEPS
|.||| . .|   .    |||  ||..| .||||||    ..| . |  | | |.. ||
YIAPEVLNKKGHSFEV--DIWSIGCIMYILLFGQPPFE-TKCLKETYSRIKKNEYRIPS
Kinase 11408.AA STE 5008-5033 46 4e-06 17.76 In-house 332-359 (359) Show / Hide 
Range on Protein: 5008-5033
Range on HMM: 332-359/359
Sequence Identity: 46% (13 aa)

DLISACLQYTPSKRPTVEGLLQ--SPVF
| |. |||. |.||||.. ||.   | .
DFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 11408.AA RSK 4873-4908 35 1.2e-05 16.97 In-house 174-211 (278) Show / Hide 
Range on Protein: 4873-4908
Range on HMM: 174-211/278
Sequence Identity: 35% (14 aa)

YLAPEQILR---KTADWNAYSDIWGFGCLLYHILFGQPP
|.||| .|.   .    ..  |.| .|.|.|  |.|.||
YMAPE-MLKRANQQGGHDKACDWWSLGVLMYEMLTGCPP
Kinase 11408.AA ULK 4890-4925 24 2.1e-05 14.95 In-house 237-285 (329) Show / Hide 
Range on Protein: 4890-4925
Range on HMM: 237-285/329
Sequence Identity: 24% (12 aa)

SDIWGFGCLLYHILFGQPP--KSFYQSLI-----DRYGD-------IDKE
.||| .||..| .|.|.||  .. .....     . . .       |.|.
CDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQ
Kinase 11408.AA Ciliate-E2-Unclassified 5005-5033 36 2.6e-05 14.43 In-house 320-352 (352) Show / Hide 
Range on Protein: 5005-5033
Range on HMM: 320-352/352
Sequence Identity: 36% (12 aa)

EVLDLIS----ACLQYTPSKRPTVEGLLQSPVF
|. |.|.     .|.. |.||.| | .|. | |
EAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 11408.AA ULK 4890-4913 37 4.9e-05 13.89 In-house 233-258 (324) Show / Hide 
Range on Protein: 4890-4913
Range on HMM: 233-258/324
Sequence Identity: 37% (10 aa)

SDIWGFGCLLYHILFGQPP---KSFYQ
.||| .||..| .|.|..|     |..
CDIWSLGCIFYEMLYGKYPFFSW-FND
Kinase 11408.AA ULK 5004-5033 40 0.000122 12.22 In-house 300-329 (329) Show / Hide 
Range on Protein: 5004-5033
Range on HMM: 300-329/329
Sequence Identity: 40% (12 aa)

SEVLDLISACLQYTPSKRPTVEGLLQSPVF
.|. |||. .||| ...| . | |.. |.|
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 11408.AA ULK 5004-5033 36 0.000134 12.31 In-house 295-324 (324) Show / Hide 
Range on Protein: 5004-5033
Range on HMM: 295-324/324
Sequence Identity: 36% (11 aa)

SEVLDLISACLQYTPSKRPTVEGLLQSPVF
.|. |||. .||| ...| . | ... |.|
PECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 11408.AA STE 4873-4908 30 0.000225 11.5 In-house 228-267 (359) Show / Hide 
Range on Protein: 4873-4908
Range on HMM: 228-267/359
Sequence Identity: 30% (12 aa)

YLAPEQILRKTAD----WNAYSDIWGFGCLLYHILFGQPP
. ||| |.. . .     .. .||| .||.. . . |.||
WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase 11408.AA RSK 5008-5033 35 0.000246 12.18 In-house 248-278 (278) Show / Hide 
Range on Protein: 5008-5033
Range on HMM: 248-278/278
Sequence Identity: 35% (11 aa)

DLISACLQYTPSKRPT-----VEGLLQSPVF
|||...|.  |.||..     .| ..|.| |
DLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 11408.AA Pkinase 4872-4908 40 0.000445 15.5 Pfam 176-211 (293) Show / Hide 
Range on Protein: 4872-4908
Range on HMM: 176-211/293
Sequence Identity: 40% (15 aa)

PYLAPEQILRKTADWNAYSDIWGFGCLLYHILFGQPP
.|.||| |. .  ..   .|.|..||.||  |.|.||
WYMAPEVIR-GGQYYGPKVDMWSCGCILYEMLCGRPP
Kinase 11408.AA PLK1 5008-5033 38 0.000928 7.94 In-house 228-253 (253) Show / Hide 
Range on Protein: 5008-5033
Range on HMM: 228-253/253
Sequence Identity: 38% (10 aa)

DLISACLQYTPSKRPTVEGLLQSPVF
.|| . |.  |..|||.| .|.   |
QLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase 11408.AA AGC 5008-5033 27 0.003005 2.66 In-house 360-395 (395) Show / Hide 
Range on Protein: 5008-5033
Range on HMM: 360-395/395
Sequence Identity: 27% (10 aa)

DLISACLQYTPSKRPT----------VEGLLQSPVF
|||. .|.  |.||..          .| . . | |
DLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 11408.AA CMGC 4873-4900 25 0.010471 3.68 In-house 291-326 (513) Show / Hide 
Range on Protein: 4873-4900
Range on HMM: 291-326/513
Sequence Identity: 25% (9 aa)

YLAPEQILRKT--------ADWNAYSDIWGFGCLLY
| ||| .|. .         ...   |.|..|| ..
YRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFA
Pkinase 11408.AA Pkinase 4795-4810 35 9.89525 0.13 Pfam 136-154 (293) Show / Hide 
Range on Protein: 4795-4810
Range on HMM: 136-154/293
Sequence Identity: 35% (7 aa)

PENIFINRHTYEI----KLA
||||.|. ....|    |..
PENILID-NNGHIDACVKIC