Gene 12475 (Tetrahymena)
12475
Group:
Other
Family:
Ciliate-D1
Sequence
Protein domains of 12475.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 12475.AA | Ciliate-E1 | 91-156 | 17 | 0.194855 | 1.02 | In-house | 137-202 (202) | Show / Hide |
Range on Protein: 91-156 Range on HMM: 137-202/202 Sequence Identity: 17% (12 aa) PKNSIIMKFEKFTQK-VFIRKVLNHKEINMSQFNNFLDNLAQQKQSFTPEIIKLDKKEMANKNTCSF |.| .| ..... | |.|. .... .|........... | ..|| . .|.. |... . PQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKINYKSDIY |
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| Kinase | 12475.AA | Ciliate-E1 | 168-240 | 29 | 4.4e-12 | 36.03 | In-house | 100-174 (202) | Show / Hide |
Range on Protein: 168-240 Range on HMM: 100-174/202 Sequence Identity: 29% (22 aa) NANEQIWEFL--QYSFCQLNEKLNQMHQLKIVHGDIKPQNIILSKEGSCYFIDFDASIQINDNDIQPSFISDHLK . |.. . |. . ..|| . |...||..| |.|||||||. ...| . . || | ... |..| . .. ... QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTH |
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| Kinase | 12475.AA | Ciliate-E2b | 188-219 | 37 | 5.5e-09 | 23.61 | In-house | 115-146 (272) | Show / Hide |
Range on Protein: 188-219 Range on HMM: 115-146/272 Sequence Identity: 37% (12 aa) LNQMHQLKIVHGDIKPQNIILSKEGSCYFIDF | |...|...|||| ||.. ..| .. ||. LEYLHNQNIIYRDIKPENIMVDHKGYMKLIDM |
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| Kinase | 12475.AA | AGC | 188-219 | 38 | 1.2e-08 | 16.91 | In-house | 166-199 (395) | Show / Hide |
Range on Protein: 188-219 Range on HMM: 166-199/395 Sequence Identity: 38% (13 aa) LNQMHQ-LKIVHGD-IKPQNIILSKEGSCYFIDF | .|. ..|.| | .|| || | ..| . || LEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDF |
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| Kinase | 12475.AA | Ciliate-B2 | 183-219 | 43 | 2.2e-08 | 15.71 | In-house | 112-148 (197) | Show / Hide |
Range on Protein: 183-219 Range on HMM: 112-148/197 Sequence Identity: 43% (16 aa) QLNEKLNQMHQLKIVHGDIKPQNIILSKEGSCYFIDF || . | |.. |.| ||||||| ....| . || QLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDF |
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| Kinase | 12475.AA | DAPK | 191-213 | 43 | 6.2e-08 | 17.63 | In-house | 119-141 (264) | Show / Hide |
Range on Protein: 191-213 Range on HMM: 119-141/264 Sequence Identity: 43% (10 aa) MHQLKIVHGDIKPQNIILSKEGS .|...|.| |.||||| |. ... LHSRNICHLDLKPQNIMLTDRNI |
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| Kinase | 12475.AA | STE | 192-227 | 38 | 8.7e-08 | 23.7 | In-house | 169-199 (359) | Show / Hide |
Range on Protein: 192-227 Range on HMM: 169-199/359 Sequence Identity: 38% (14 aa) HQLKIVHGDIKPQNIILSKEGSCYFIDFDASIQIND |...|.| ||||.|| | . .|| . |..| HSHHIIHRDIKPANILL-----VKLCDFGVCGQLTD |
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| Kinase | 12475.AA | NEK1 | 181-213 | 51 | 1.4e-07 | 22.49 | In-house | 110-144 (276) | Show / Hide |
Range on Protein: 181-213 Range on HMM: 110-144/276 Sequence Identity: 51% (18 aa) FCQLNEKLNQMHQLKIVHGDIKPQNIILS--KEGS |||. || .| || | |||.||| |. | |. FCQICLALNHIHDRKILHRDIKSQNIFLTISKNGM |
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| Kinase | 12475.AA | MSK | 188-219 | 42 | 1.5e-07 | 21.57 | In-house | 114-148 (277) | Show / Hide |
Range on Protein: 188-219 Range on HMM: 114-148/277 Sequence Identity: 42% (15 aa) LNQMHQLKIVHGDIKPQNIILSKE---GSCYFIDF . .|||..|.|.|.|| || . | | ||| VDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDF |
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| Kinase | 12475.AA | CMGC | 188-219 | 19 | 1.5e-07 | 19.94 | In-house | 193-248 (513) | Show / Hide |
Range on Protein: 188-219 Range on HMM: 193-248/513 Sequence Identity: 19% (11 aa) LN--QMHQLK--IVHGDIKPQNIILSKEGSC--------------------YFIDF |. .|. . |.| |.||.|| ..... . .|| LKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDF |
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| Kinase | 12475.AA | RSK | 188-228 | 33 | 1.6e-07 | 23.92 | In-house | 117-161 (278) | Show / Hide |
Range on Protein: 188-228 Range on HMM: 117-161/278 Sequence Identity: 33% (15 aa) LNQMHQLKIVHGDIKPQNIILSK---EGSCYFIDFDASIQ-INDN . .||..|.| |.|| ||.. ||. .||. . | .|. VEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDH |
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| Kinase | 12475.AA | Pkinase | 191-229 | 29 | 0.000116 | 17.56 | Pfam | 124-166 (293) | Show / Hide |
Range on Protein: 191-229 Range on HMM: 124-166/293 Sequence Identity: 29% (13 aa) MHQLKIVHGDIKPQNIILSKEGSC----YFIDFDASIQI-NDND .|. .|.| |.||.|| ....| . .|| . |. . |. CHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NN |
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