Gene 13052 (Tetrahymena)

13052

Species: Tetrahymena
Alias: 454, 4.m00451, TTHERM_00058670, 13052, PreTt13052, 3707.m00096
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
13052.AA Protein None 362 None Fasta, JSON
13052.kin_dom Protein Kinase Domain None 322 None Fasta, JSON
13052.NA RNA None 1089 None Fasta, JSON

Protein domain

Protein domains of 13052.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13052.AA CMGC 15-336 19 5.4e-78 255.67 In-house 1-513 (513) Show / Hide 
Range on Protein: 15-336
Range on HMM: 1-513/513
Sequence Identity: 19% (104 aa)

YQQIKSLGQGAYAEVFACRYIGQQEKQHQVPSFTLDRLYQESKEKPKA--------GELFAIKKFKDNGQNRLG---------LSMDNIREIRFMQQFN-
|. || .|.|.|..|. ||    ..|.                             .|. ||||.| .  .  .         ...  .|||......| 
YEIIKKIGEGTYGVVYKCRDKRTNQKKD-------------------NGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNK

----------------HPNIVKIVDVFIVQNENSQNEK--------QSNLMIVMPLCVP-IHKLLELKR-------IDSFKEED------------FKCM
                |.||||. |.|   |.......          .| .|. ..    ..... ..          ..|               |..
NHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYF

F------KQILQGVK--YLHENY--ILHRDIKWENLLIDKDRK--------------------IVITDFGLSREFGST---------------------E
.      .|||.|.|  |.| .   |.|||.| ||.||... .                    . | ||||.| ...                       
MIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPN

RIFTTNMFTANYRPPEIILGS---------AKYGPKSDMWAIGVVFMEILMKFE------KFLFPITSDNN---------VEILNCIFALRGTPD-----
| .|..  |  ||.|||.||.          .|... |||..| .| |.... .      | |||  |...         .. |..|| . |||.     
RPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQK

----------QETWKDYDQLPLKIK---------------------------FNPVQAKKLKNLDVLQG-------------------------------
          .|.| .. .||  .|                           | ... |..|||   .                                
GKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKR

--YSDGLVDVLERLLQLNPNKRPTAAELLEDKYF
   .. ..| |...||..|.||.||.. |.  ||
KCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 13052.AA CDK 67-336 29 1.6e-71 228.09 In-house 33-284 (284) Show / Hide 
Range on Protein: 67-336
Range on HMM: 33-284/284
Sequence Identity: 29% (87 aa)

AIKKFKDNGQ--NRL--GLSMDNIREIRFMQQFNHPNIVKIVDVFIVQNENSQNEKQ---SNLMIVMPLCVP-IHKLLELKRIDSFKEEDFKCMFKQILQ
|.||..   .  ..   |...  ||||  ...  ||||||. ||..  |  ..| |.   ..| .|.. .     |...            ||...|.|.
ALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFEYMDHDLKKYMD-----------IKCYMWQLLR

GVKYLHENYILHRDIKWENLLIDKDRK-----IVITDFGLSREFGS------TERIFTTNMFTANYRPPEIILGSAKYG--PKSDMWAIGVVFMEILM-K
|. |.|.| |.|||.|  |.||... .     . |.||||.|.||.        | .| .. |  ||.||. ||| .|.  .  |||..| .| |...  
GLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDV

FEKFLFPITSDNNVEILNCIFALRGTPDQETWKDYDQLPLKIKFNPVQAKKLKNLDVLQGYSDGLVDVLERLLQLNPNKRPTAAELLEDKYF
  | ||| .|.   . | .|| . |||. ..| .  .||.                          | |...|...|.|| .| . |...||
TRKPLFPGDSE--IDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 13052.AA S_TKc 15-336 23 1.1e-70 242.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-336
Range on HMM: 1-231/231
Sequence Identity: 23% (80 aa)

YQQIKSLGQGAYAEVFACRYIGQQEKQHQVPSFTLDRLYQESKEKPKAGELFAIKKFKDNGQNRLGLSMDNIREIRFMQQFNHPNIVKIVDVFIVQNENS
|. .. .|.||...|. || ..                          |...|||. |           . .|||. ... .||||||. |||       
YEILRKIGKGAFGKVYKCRHKK-------------------------TGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-----

QNEKQSNLMIVMPLCV----PIHKLLELKRI----DSFKEEDFKCMFKQILQGVKYLHENYILHRDIKWENLLIDKDRKIVITDFGLSREFGSTERIFTT
     ..| .|| .|       ..... ..       | | . .....||.....|.|.. |.|||.| ||.|.|.   | |.||||.|..       ||
-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TT

NMFTANYRPPEIILGSAKYGP-KSDMWAIGVVFMEILMKFEKFLFPITSDNNVEILNCIFALRGTPDQETWKDYDQLPLKIKFNPVQAKKLKNLDVLQGY
   | .|..||..    .||. |.|.|..|... | |    . .||    .  .... |                                         
FCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC--GYPPFP----QMQMMFKKIG----------------------------------------

SDGLVDVLERLLQLNPNKRPTAAELLE-------DKYF
|. . | ....|| .|.||||| |.|.       . .|
SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 13052.AA Pkinase 15-336 26 3.7e-69 240.85 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-336
Range on HMM: 1-293/293
Sequence Identity: 26% (90 aa)

YQQIKSLGQGAYAEVFACRYIGQQEKQHQVPSFTLDRLYQESKEKPKAGELFAIKKFKDNGQNRLGLSMDNIR--EIRFMQQFNHPNIVKIVDVFIVQNE
|. .. .|.|....|. |. .| ..                         ..|.|..|    .. .  . ..|  ||. |. .||||||.. |.|     
YHIGRKIGSGSFGCVYKCHHKGTGK-------------------------IVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED---

NSQNEKQSNLMIVMPLCVP-IHKLLELKRIDS------F--KEEDFKCMFKQILQGVKYLHENYILHRDIKWENLLIDKDRKI----VITDFGLSREF-G
       ... .||..|    . ...|... |      |   |.. |....|||.|..|.|.. |.|||.| ||.|||..  |     |.||||.. |  
------KDHIYMVMEYCEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY

STERIFTTNMFTANYRPPEIILGSAKYGPKSDMWAIGVVFMEILMKFEKFLFPIT--SDNNVEILNCIFALRGTPDQETWKDYDQLPLKIKFNPVQAKKL
   . .||   | .|..||.|.|. .||||.|||..|... | | .   ..||    .|| .. . .|.  .|.|  . |   .  ..   |.. . .  
-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR--PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--

KNLDVLQGYSDGLVDVLERLLQLNPNKRPTAAELLEDKYF
. . ..   |. . |.....|...|.|||||...|....|
F-HWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 13052.AA CDC2 86-336 34 8.8e-54 163.4 In-house 48-301 (301) Show / Hide 
Range on Protein: 86-336
Range on HMM: 48-301/301
Sequence Identity: 34% (91 aa)

IREIRFMQQFN-HPNIVKIVDVFIVQNENSQNEKQSNLMIVMPLCVPIHKLLE--LKRIDSFKEEDFKCMFKQILQGVKYLHENYILHRDIKWENLLIDK
||||  ..  . ||||||. ||..          ..  |.   |     |...  ..  ... ..  |  ..|||||| ..| . |.|||.|  |.||||
IREISCLKELKDHPNIVKLHDVIHQ---------NKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDK

DRKIVITDFGLSREFGSTERIFT--TNMFTANYRPPEIILGSAKYGPKSDMWAIGVVFMEILMK-FEKFLFPITSDNNVEILNCIFALRGTPDQETWKDY
. .| | ||||.| ||   |  |   .  |  ||.||| ||. .|    |||.|| .| |. |.   | ||.   |   . |  ||  .|||. .|| . 
KGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEMFMDVTKKPLFH--GDSEIDQLFKIFRILGTPNEQTWPGV

DQLP-LKIKFNPVQAKKLKNLDVL-------QGYSDGLVDVLERLLQLNPNKRPTAAELLEDKYF
.|||  | .|   ....|...              .  .|.|...||..|.|| .| | |. .||
TQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 13052.AA CDK7 148-336 35 1.3e-53 140.94 In-house 103-288 (288) Show / Hide 
Range on Protein: 148-336
Range on HMM: 103-288/288
Sequence Identity: 35% (68 aa)

DFKCMFKQILQGVKYLHENYILHRDIKWENLLIDKDRKIVITDFGLSREFGSTERIFTTNMFTANYRPPEIILGSAKYGPKSDMWAIGVVFMEILMKFEK
. |   ...|||. |.| |.|||||.|  |||.... .. |.|||| | .||  ||.| .  |  || ||   |   ||.  |||..|..| | .     
HIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRVP-

FLFPITSDNNVEILNCIFALRGTPDQETWKDYDQLPLKIKFNPVQA---KKLKNLDVLQGYSDGLVDVLERLLQLNPNKRPTAAELLEDKYF
  .| .||  .  |  ||   |||  |.| .  ...  ||| .  .     |...      || |.| ..... .|| || |... |. .||
-YLPGDSD--IDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHI--FTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 13052.AA CAMK 20-237 20 7.3e-48 151.89 In-house 1-323 (425) Show / Hide 
Range on Protein: 20-237
Range on HMM: 1-323/425
Sequence Identity: 20% (69 aa)

SLGQGAYAEVFACRYIGQQEKQ---HQVPSFTLDRLYQESKEKPKAGELFAIKK------------------------FKDNGQNRLGLSMDNIR-EIRF
 ||.|....|. |. .  . |.   |               .  . |. .|||                          |.....| . ...|.| ||. 
TLGRGSFGKVKLCIHKNTTGKERVHH---------------IYTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEI

MQQ-------FNHPNIVKIVDVFIVQN--------ENSQN---EKQSNLMIVM---PLCVP-------IHKLLELKRI------------DSFKEEDFKC
|..        .||||.|. .|.   .        |. ..   .|.... .||    .|           .. | ..               |.|.. . 
MKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARR

MFKQILQGVKYLHENYILHRDIKWENLLIDKD-----------------RKIVITDFGLSREFGSTER-----------------------IFTTNMFTA
.|.||...|.|.|.. | |||.| ||.|.|..                  .| |.|||....| . |                         ..|   | 
YFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTP

NYRP-PEIILG-------------SAKYGPKSDMWAIGVV
 | . ||...|                ||||.|||..||.
EYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVI
Kinase 13052.AA CAMKL 15-237 25 1.5e-43 136.79 In-house 1-225 (297) Show / Hide 
Range on Protein: 15-237
Range on HMM: 1-225/297
Sequence Identity: 25% (65 aa)

YQQIKSLGQGAYAEVFACRYIGQQEKQHQVPSFTLDRLYQESKEKPKAGELFAIKKFKDNGQNRLGLSMDN------------IREIRFMQQFN---HPN
|. .| ||.|....|  .. |  .                        ||  |||  . .. .    ...|             |||. |...|   |||
YRIGKTLGKGSFGKVKLATHIRTT------------------------GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPN

IVKIVDVFIVQNENSQN--EKQSNLMIVMPLCV--P--IHKLLELKRIDS--FKEEDFKCMFKQILQGVKYLHENYILHRDIKWENLLIDKDR--KIVIT
|.|. .|.    |....  |  . . .|| .|       .  .. ..     ..|.. . .|.||. .|.|.|.. | ||||| ||.|.|..   .| |.
IIKLYEVI----ETPEHDIET-KKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKII

DFGLSREFGS----TERIFTTNMFTANYRPPEIILG--SAKYGPKSDMWAIGVV
|||.| ..      ... ..|   . .| .|||..|     .||| |.|..||.
DFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVI
Kinase 13052.AA CDK10 61-336 33 6.4e-43 147.0 In-house 22-285 (285) Show / Hide 
Range on Protein: 61-336
Range on HMM: 22-285/285
Sequence Identity: 33% (92 aa)

KAGELFAIKKFKDNGQNRLGLSMDNIREIRFMQQFNHPNIVKIVDVFIVQNENSQNEKQSNLMIVMPLCVPIHKLLELKRIDSFKEEDFKCMFKQILQGV
.. |. |.|| . . . . || .  .|||  . |  |.|||.. .| . |  .|       . .||  |      |       | | . ||.  |.|.|.
RSDEIVALKKVRMD-KEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDS-------IFLVMQYCEQDLASLLDNMPQPFTETQVKCIMLQMLRGL

KYLHENYILHRDIKWENLLIDKDRKIVITDFGLSREFGSTERIFTTNMFTANYRPPEIILGSAKYGPKSDMWAIGVVFMEILMKFEKFLFPITSDNNVEI
||||.|...|||.|  |||.  .  | . |||| | .|   .  |  | |  || ||..||. .     ||||.| .  |.|.  .| |.| .|.  .  
KYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLV--HKPLMPGNSE--IHQ

LNCIFALRGTPDQETWKDYDQLPLKIKFNPVQAKKLKNLDV-LQGYSDGLVDVLERLLQLNPNKRPTAAELLEDKYF
.. |  | |||... |  . .||.  .|  .. .   ||    .  |.    .|. |.  || || || | || .||
IDMIIDLLGTPSENIWPGFSDLPMVQNFT-LKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase 13052.AA Ciliate-E2 15-336 21 6e-42 141.77 In-house 1-365 (365) Show / Hide 
Range on Protein: 15-336
Range on HMM: 1-365/365
Sequence Identity: 21% (89 aa)

YQQIKSLGQGAYAEVFAC-RYIGQQEKQHQVPSFTLDRLYQESKEKPKAGELFAIKKFKDNGQNRLGLSMDNIREIR----------FMQQFNHPNIVKI
|  || .|||... |. | ..  |.......   ..   .|.  .   .. ..|.| .| |. . .    . .|||.           ..| |||||.|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQM-QEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKM

VDVFIVQNENSQNEKQSNLMIVMPLCVP--IHKLLELKRIDSFKE--------EDFKC-MFKQILQ---------------GVKYLHENY-ILHRDIKWE
...|       |.....|. .|| .|      .... ... ...|        |   . ..|||||               ...|||..  |.||||| |
YECF-------QEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPE

NLLIDKDRKIVITDFGLSREFG-------------------STERIFT-------TNMF-----TANYRPPEIILGSAK--------YGPKSDMWAIGVV
|.|.     | |.|||||...                     |.| ..        |||     |..| .|||. |           |. |.|.|..||.
NILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVI

FMEILMKFEKFLFPITSDNNVEILNCIFALRGTPDQETWKDYDQLPLKIKFNPVQAKKLKNLD------------------VLQGYSDGLVDVLER----
. | |..   |                                           | .| ...|                    .  |.   | . .    
LYEMLFGKPPF------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKR

LLQLNPNKRPT-AAELLEDKYF
.|| .|.||.| . ..|. ..|
MLQKDPEKRITGWEQILNHPWF
Kinase 13052.AA PITSLRE 139-336 35 3.4e-38 133.2 In-house 98-295 (295) Show / Hide 
Range on Protein: 139-336
Range on HMM: 98-295/295
Sequence Identity: 35% (72 aa)

KRIDSFKEEDFKCMFKQILQGVKYLHENYILHRDIKWENLLIDKDRKIVITDFGLSREFGSTERIFTTNMFTANYRPPEIILGSAKYGPKSDMWAIGVVF
.| ..||.   ||.  | | ||...| | |.||| |  |||.       | |||| ||.||  . .| .. |  || ||. ||. || .  ||| .| .|
RRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIF

MEILMKFEKFLFPITSDNNVEILNCIFALRGTPDQETWKDYDQLPLKIKFNPVQAKKLKNLDVLQG----YSDGLVDVLERLLQLNPNKRPTAAELLEDK
 |....  | ||.   .. .. .|||| . |||    | ..  ||.  ..|  .  .  ||  . .     ||   | | ..| .|| .| || . | . 
AEFITM--KPLFQ--GKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHP

YF
.|
WF
Kinase 13052.AA STE 15-242 20 7.4e-33 113.39 In-house 1-262 (359) Show / Hide 
Range on Protein: 15-242
Range on HMM: 1-262/359
Sequence Identity: 20% (60 aa)

YQQIKSLGQGAYAEVFACRYI--------GQQEKQHQVPSFTLDRLYQESKEKPKAGELFAIKKFK--DNG-----------QNRLGLSM-DNIREIRFM
.. |. .|.||. .|. ....        |..|.                  . . ||..|||. .  ..            .|.    | . ..||..|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVEN------------------NGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIM

QQFN--HPNIVKIVDVFIVQNENSQNEKQ-SNLMIVMPLCV--PIHKLLELKRIDSFK------------EEDFKCMFKQILQG-VKYLHENYILHRDIK
...|  ||||||  . ... ..|   .|. ..| |.| ..    . .... | .  .             |.  ... .|||.|  .|||.. | |||||
KKCNHMHPNIVKYYGCYFKEGHN---HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIK

WENLLIDKDRKIVITDFGLSREFGS---------------TERIFTTNMF-TANYRPPEIILG-----SAKYGPKSDMWAIGVVFMEIL
  | |.     . ..|||..  . .               |    .. .  |  .  ||.|..     . .|. |.|.| .| . .| .
PANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMA
Kinase 13052.AA TyrKc 15-334 20 1.3e-15 29.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-334
Range on HMM: 1-280/280
Sequence Identity: 20% (71 aa)

YQQIKSLGQGAYAEVFACRYIGQQEKQHQVPSFTLDRLYQESKEKPKAGELFAIKKFKDNGQNRLGLSMDNIREIRFMQQF--NHPNIVKIVDVFIVQNE
 . .| || ||. ||. ....                            .  |.|. |..        .| .||.| | ..  .|||||... | . | .
ITLGKKLGEGAFGEVYKGTWK----------------------------IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGR

NSQNEKQ---SNLMIVMPLCVPI--HKLLELKRIDSFKEEDFKCMFKQILQGVKYLHENYILHRDIKWENLLIDKDRKIVITDFGLSREFGST-------
|           ||||| ..     .. |  .| . .. .|.  .  || .|  |||.. . |||.   | |..... . |.||||||. ..        
N-----FMYIEPLMIVMEYMPHGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESK

ERIFT-----TNM-FTANYRPPEIILGSAKYGPKSDMWAIGVVFMEILMKFEKFLFPITS--DNNVEILNCIFALRGTPDQET----WKDYDQLPLKIKF
. . .     ... .     .|| |    |. .||| |. ||.  ||.   ..    ..    .| |..... . .  |  .                  
DYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------

NPVQAKKLKNLDVLQGYSDGLVDVLERLLQLNPNKRPTAAELLEDK
               . .| . .. ..  . .|..||| .|. |. 
------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 13052.AA Pkinase_Tyr 15-195 24 1.6e-14 49.77 Pfam 1-159 (270) Show / Hide 
Range on Protein: 15-195
Range on HMM: 1-159/270
Sequence Identity: 24% (46 aa)

YQQIKSLGQGAYAEVFACRYIGQQEKQHQVPSFTLDRLYQESKEKPKAGELFAIKKFKDNGQNR-LGLSMDNIREIRFMQQF-NHPNIVKIVDVFIVQNE
 . .| ||.||. ||. ... |                     .. . .   |.|. |..   . . .. | .||.. | |. .|||||. . | . | |
ITFGKKLGEGAFGEVYKGTWKG---------------------DPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGE

NSQNEKQSNLMIVMPLCVP--IHKLLELK--RIDSFKEEDFKCMFKQILQGVKYLHENYILHRDIKWENLLIDKDRKIVITDFGLSR
 .      ...|||...     .. |  .    .... .|  .|  || .|  ||... . |||.   | |....... |.||||.|
PN------QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase 13052.AA CAMKL 306-336 32 8.7e-09 24.02 In-house 268-297 (297) Show / Hide 
Range on Protein: 306-336
Range on HMM: 268-297/297
Sequence Identity: 32% (10 aa)

SDGLVDVLERLLQLNPNKRPTAAELLEDKYF
|  . | . ..|| ||.||||. ...... .
S-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 13052.AA CDK7 63-107 33 1e-08 18.86 In-house 24-71 (288) Show / Hide 
Range on Protein: 63-107
Range on HMM: 24-71/288
Sequence Identity: 33% (16 aa)

GELFAIKKFK---DNGQNRLGLSMDNIREIRFMQQFNHPNIVKIVDVF
|.  |||| |      . . |. .  ||||   |   |.|..  .|.|
GQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIF
Kinase 13052.AA STE 305-336 38 2.3e-08 25.78 In-house 326-359 (359) Show / Hide 
Range on Protein: 305-336
Range on HMM: 326-359/359
Sequence Identity: 38% (13 aa)

YSDGLVDVLERLLQLNPNKRPTAAELLE--DKYF
.|. . | ... || .||||||| .||.   . .
WSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 13052.AA CAMK 306-336 29 2.3e-08 22.3 In-house 395-425 (425) Show / Hide 
Range on Protein: 306-336
Range on HMM: 395-425/425
Sequence Identity: 29% (9 aa)

SDGLVDVLERLLQLNPNKRPTAAELLEDKYF
|.   | . ..|| .|.||.|... |... .
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 13052.AA CDK 15-33 31 3.3e-05 12.42 In-house 1-19 (284) Show / Hide 
Range on Protein: 15-33
Range on HMM: 1-19/284
Sequence Identity: 31% (6 aa)

YQQIKSLGQGAYAEVFACR
|.... .|.|.|..|. .|
YEKLEKIGEGTYGVVYKAR
Kinase 13052.AA CDK7 15-30 43 0.00441 3.57 In-house 1-16 (288) Show / Hide 
Range on Protein: 15-30
Range on HMM: 1-16/288
Sequence Identity: 43% (7 aa)

YQQIKSLGQGAYAEVF
|. || .| | .| |.
YEKIKHIGEGQFATVY
Kinase 13052.AA CDC2 15-33 42 0.006052 4.3 In-house 1-19 (301) Show / Hide 
Range on Protein: 15-33
Range on HMM: 1-19/301
Sequence Identity: 42% (8 aa)

YQQIKSLGQGAYAEVFACR
||.|. .| | | .|. |.
YQKIEKIGEGTYGVVYKCK
Kinase 13052.AA PITSLRE 61-103 28 0.033176 4.09 In-house 22-66 (295) Show / Hide 
Range on Protein: 61-103
Range on HMM: 22-66/295
Sequence Identity: 28% (13 aa)

KAGELFAIKKFKDN-GQNRLGLSMDNIREIR-FMQQFNHPNIVKI
. .|  |.|..|    . . |     .|||       .|||||..
RTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNV