Gene 14780 (Tetrahymena)

14780

Species: Tetrahymena
Alias: PreTt14780, 1081, 242.m00027, TTHERM_01119400, 14780
External Links: Tetrahymena Genome Database (TGD) ,
Annotation:

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C8

Sequence

Name Sequence Type Origin Length Description Download
14780.AA Protein None 210 None Fasta, JSON
14780.kin_dom Protein Kinase Domain None 88 None Fasta, JSON
14780.NA RNA None 633 None Fasta, JSON

Protein domain

Protein domains of 14780.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 14780.AA Ciliate-C8 1-99 40 2.2e-47 163.72 In-house 45-164 (238) Show / Hide 
Range on Protein: 1-99
Range on HMM: 45-164/238
Sequence Identity: 40% (49 aa)

MQKLKEPLVVQLYDSYIVENNVGPDR-----------------YSVFELEKCS--CSLDEYLER-QNKDGQLNEDNKFQIAIQIIDSVNYIHSFNIIHRD
||....|.|||.||......   ...                 ..|.|.|||.  |.|..|..| ..|....... |..||||.||||||.| |||.|||
MQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNCNLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRD

IKPENFLVYLD-EKQPEIKL
|||.||||..| ..||.|||
IKPHNFLVCFDQQYQPTIKL
Kinase 14780.AA C8 1-99 44 2.7e-40 137.56 In-house 47-168 (226) Show / Hide 
Range on Protein: 1-99
Range on HMM: 47-168/226
Sequence Identity: 44% (54 aa)

MQKLKEPLVVQLYDSYIVENNVGPDRYSVFELEKCS-----------CSLDE-----------YLERQNKDGQLNEDNKFQIAIQIIDSVNYIHSFNIIH
|.....|.|.|.||.|. |.......|.|||.||||           |...|           |.||.||..|.....|..||||.||.|||||..||.|
MKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEMELCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMH

RDIKPENFLVYLDEKQP-EIKL
|||||.||||.||.... ||||
RDIKPHNFLVCLDQNYGFEIKL
Kinase 14780.AA C2 1-177 24 5.3e-28 92.83 In-house 43-245 (245) Show / Hide 
Range on Protein: 1-177
Range on HMM: 43-245/245
Sequence Identity: 24% (51 aa)

MQKLK-EPLVVQLYDSYIVENNVGPD-------------R----------YSVFELEKCSCSLDEYLERQNKDG-QLNEDNKFQIAIQIIDSVNYIHSFN
|....  |.....|... .  |   |             .            |.|.|.|.. |  |..|. |.  ..... | ..|||..||.||.| |.
MRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQEFCQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFD

IIHRDIKPENFLVYLDEKQ-PEIKLQI--------YKFINLLVLSDSAQRASLYDIV-EQSDIKFFSNSKEMKQIVQKTLLIQNDKKIEQNATIEINSLE
|.||||||.|||. .|... | |||..         .|     |. .  | .   .. .|....  .  .  ..| .| . .          |. ...||
IVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKKCDFDFASKLKYNKSRIHFSKFKWTQQYYQHIFAPEVYQNIYKKNSDLFS--------TVGYVLLE

DLSKIQNYNIVT
 | ..| |.|  
-LDNMQQYTICC
Kinase 14780.AA Ciliate-E1 1-94 30 2e-17 53.59 In-house 49-147 (202) Show / Hide 
Range on Protein: 1-94
Range on HMM: 49-147/202
Sequence Identity: 30% (32 aa)

MQKLKEPL-VVQLYDSYIVENNVGPDRYSVFELEKCSCSLDEYLE----------RQNKDGQLNEDNKFQIAIQIIDSVNYIHSFNIIHRDIKPENFLVY
|. .|.   ..|..| .....| .    ... .|.|.||| .||.           |....|.....| ||..|.|| ....|..|||||||||.| |..
MK-FKKECYIIQIIDYIKIDQNYI----CIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILIN

LDEKQ
 . ..
NQ-GN
Kinase 14780.AA Ciliate-B2 9-88 32 1.9e-14 30.27 In-house 62-137 (197) Show / Hide 
Range on Protein: 9-88
Range on HMM: 62-137/197
Sequence Identity: 32% (26 aa)

VVQLYDSYIVENNVGPDRYSVFELEKCSCSLDEYLERQNKDG-QLNEDNKFQIAIQIIDSVNYIHSFNIIHRDIKPENFLV
||.. |.  .....      |. .||| ||| . |.. .|   . |. . .|.  | ||    ... ||.| ||||.| |.
VVKYIDHIQINETI-----DVLIMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILF
Kinase 14780.AA RAD53 63-87 56 4.5e-14 37.81 In-house 117-141 (305) Show / Hide 
Range on Protein: 63-87
Range on HMM: 117-141/305
Sequence Identity: 56% (14 aa)

QIIDSVNYIHSFNIIHRDIKPENFL
|..|.|.|.|. .|.|||.|||| |
QMCDAVKYLHDNGICHRDLKPENIL
Kinase 14780.AA Aur 63-88 65 4.7e-14 32.96 In-house 109-134 (257) Show / Hide 
Range on Protein: 63-88
Range on HMM: 109-134/257
Sequence Identity: 65% (17 aa)

QIIDSVNYIHSFNIIHRDIKPENFLV
||.. ..| || ||||||||||| |.
QICNALDYCHSKNIIHRDIKPENILL
Kinase 14780.AA CK1 38-88 30 9.2e-14 44.45 In-house 114-165 (339) Show / Hide 
Range on Protein: 38-88
Range on HMM: 114-165/339
Sequence Identity: 30% (16 aa)

SLDEYLE-RQNKDGQLNEDNKFQIAIQIIDSVNYIHSFNIIHRDIKPENFLV
.|..... ... .. ..    ..||||..... |.|. ..|||||||.||..
NLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCM
Kinase 14780.AA CMGC 1-85 19 2.4e-13 39.31 In-house 75-214 (513) Show / Hide 
Range on Protein: 1-85
Range on HMM: 75-214/513
Sequence Identity: 19% (27 aa)

MQKLK-----------------EPLVVQLYDSYIVENNVGP-----------DRYSVFELEKCSCSLDEYLERQN--KDG----QLNEDN----------
...|.                 .. .|.|||..  .|. |.           ...  .  | . ..| .|.....  . |     |.|            
LKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPP

--KFQIA------IQIIDSVN--YIHSFN--IIHRDIKPEN
  .  .        ||. ...  |.|| .  |||||.||||
HNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPEN
Kinase 14780.AA CK1-Unclassified 60-88 58 2.5e-13 35.71 In-house 109-137 (244) Show / Hide 
Range on Protein: 60-88
Range on HMM: 109-137/244
Sequence Identity: 58% (17 aa)

IAIQIIDSVNYIHSFNIIHRDIKPENFLV
|| |.|. . |.|. |.|||||||.|||.
IADQMIQRIEYLHNKNFIHRDIKPDNFLM
Kinase 14780.AA Pkinase 1-88 29 8.4e-12 42.82 Pfam 54-141 (293) Show / Hide 
Range on Protein: 1-88
Range on HMM: 54-141/293
Sequence Identity: 29% (28 aa)

MQKLKEPLVVQLYDSYIVENNVGPDRYSVFELEKCSC-----SLDEYLERQNKDGQL--NEDNKFQIAIQIIDSVNYIHSFNIIHRDIKPENFLV
|..|. | .|.|||..        ...  . .| | .     .| .|...  ..| .   |.    .. ||.  ..|.|| .|||||.||||.|.
MKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDYIST-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILI
Kinase 14780.AA S_TKc 1-159 16 1.1e-05 -93.53 SMART 19-231 (231) Show / Hide 
Range on Protein: 1-159
Range on HMM: 19-231/231
Sequence Identity: 16% (39 aa)

MQKL-----------------------KEPLVVQLYDSYIVENNVGPDRYSVFELEKCSC---SLDEYLERQNKDGQ---LNEDNKFQIAIQIIDSVNYI
  |                        . | .|.|||..          .  . .| |.    .| .|...... |    ..|     .. ||.. ..|.
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYC

HSFNIIHRDIKPENFLVYLDEKQPEIKL------------------------QIYK-----------FINLLV----LSDSAQRASLYDIVEQSDIKFFS
|| .|||||.|||| |.       .||.                        .  |           .. .|.     .   | . .....         
HSHGIIHRDLKPENILLDE-----HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--------

NSKEMKQIVQKTLLIQNDK----KIEQ-------NATI
 |.|.|....| |    .|    .. |          .
-SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF