Gene 23019 (Tetrahymena)
23019
Group:
Other
Family:
Ciliate-D1
Sequence
Protein domains of 23019.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 23019.AA | Ciliate-E2b | 233-255 | 56 | 5.3e-08 | 20.57 | In-house | 111-133 (272) | Show / Hide |
Range on Protein: 233-255 Range on HMM: 111-133/272 Sequence Identity: 56% (13 aa) LLLKLQYLLNKGIFHGDIKPENI ..| |.|| |..| ..||||||| ICLCLEYLHNQNIIYRDIKPENI |
|||||||||
| Kinase | 23019.AA | Trio | 237-272 | 37 | 8.2e-07 | 12.8 | In-house | 108-144 (258) | Show / Hide |
Range on Protein: 237-272 Range on HMM: 108-144/258 Sequence Identity: 37% (14 aa) LQYLLNKGIFHGDIKPENIAITLRQG-HAAVIFLDFG ..|| | .| | ||||||. .. . . . . ||| VHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFG |
|||||||||
| Kinase | 23019.AA | Ciliate-C1 | 237-255 | 52 | 2e-06 | 11.97 | In-house | 142-160 (328) | Show / Hide |
Range on Protein: 237-255 Range on HMM: 142-160/328 Sequence Identity: 52% (10 aa) LQYLLNKGIFHGDIKPENI .||. . .|.| |.||||| IQYIHQNNICHRDLKPENI |
|||||||||
| Kinase | 23019.AA | Ciliate-E2c | 237-255 | 60 | 3e-06 | 18.11 | In-house | 127-146 (310) | Show / Hide |
Range on Protein: 237-255 Range on HMM: 127-146/310 Sequence Identity: 60% (12 aa) LQYLLNK-GIFHGDIKPENI ..|| . .|||.||||||| FKYLHKEKNIFHRDIKPENI |
|||||||||
| S_TKc | 23019.AA | S_TKc | 125-378 | 15 | 5e-06 | -88.87 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 125-378
Range on HMM: 1-231/231
Sequence Identity: 15% (44 aa)
QLLQQHIGKGSQGSVEINFLQLSKDRFQIEPQFIPIATKKFEDKFQFIRESAILTQLDKN--IRPVLAFIGNNKSEIHMELCMCTLGQFKSYIHKNNL--
. ..||||. |.| | |. ...|| .|| . . .. .| .. . ||.| || ..||.|..
YEILRKIGKGAFGKVYKCRHKK---------TGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG
----VTDNLLISLLLNLLLKLQYLLNKGIFHGDIKPENIAITLRQGHAAVIFLDFGASSWDAEDYLNYYTPAFCKFDIFQMIDSGQILNKDQIRYAEIFS
. ... ... |.|. ..|| | |.||||| .. . ||| . .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------------------------------TT
ICRTIQYV---MLPQASE-------------------SLFNQKNISQFIQLFEHKFPSTITFLECILLNNVN--SQISESQL-------QVLL
.| | |. .| . . .| .. . ... |. . |.. .| . . . | .
FCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
|||||||||
| Kinase | 23019.AA | Ciliate-E1 | 131-309 | 19 | 5e-06 | 16.23 | In-house | 1-202 (202) | Show / Hide |
Range on Protein: 131-309 Range on HMM: 1-202/202 Sequence Identity: 19% (40 aa) IGKGSQGSVEINFLQLSKDRFQIEPQFIPIATKKFEDKFQFIRESA-ILTQLDKNIRP--VLAFIGNNKSEIHMELCMCTLGQFKSYIH----------- ||.||.. | . . | .... .. . . . ... . |.| |. . |.. .. .| .. |......| ..| |. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC --KNNLVTDNLLISLLLNLLLKLQYLLNKGIFHGDIKPENIAITLRQGHAAVIFLDFGASS---------WDAEDYLNYYTPAFCKF--DIFQMIDSGQI ..| |. .... .|. |..| ...| |.||||.|| |. | .. ||| |. . . |..|| | ... . ..... .| QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GN--YVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKI -LNKDQI . | . NYKSDIY |
|||||||||
| Kinase | 23019.AA | Ciliate-E2 | 237-255 | 65 | 5e-06 | 16.65 | In-house | 173-192 (365) | Show / Hide |
Range on Protein: 237-255 Range on HMM: 173-192/365 Sequence Identity: 65% (13 aa) LQYLLNKG-IFHGDIKPENI |.|| .|. |.| ||||||| LEYLHSKNNIIHRDIKPENI |
|||||||||
| Kinase | 23019.AA | Ciliate-E2-Unclassified | 237-255 | 65 | 1.1e-05 | 15.75 | In-house | 156-175 (352) | Show / Hide |
Range on Protein: 237-255 Range on HMM: 156-175/352 Sequence Identity: 65% (13 aa) LQYLLNKG-IFHGDIKPENI |.|| |. | | ||||||| LEYLHHKNNIIHRDIKPENI |
|||||||||
| Kinase | 23019.AA | RAN | 237-255 | 63 | 1.8e-05 | 14.21 | In-house | 162-180 (324) | Show / Hide |
Range on Protein: 237-255 Range on HMM: 162-180/324 Sequence Identity: 63% (12 aa) LQYLLNKGIFHGDIKPENI . | |.||.| ||||||| INYCHNHGIYHCDIKPENI |
|||||||||
| Kinase | 23019.AA | Dicty3 | 215-255 | 33 | 3e-05 | 13.09 | In-house | 102-143 (351) | Show / Hide |
Range on Protein: 215-255 Range on HMM: 102-143/351 Sequence Identity: 33% (14 aa) IHKNNLVTDNLLISLLLNLLLKLQYLLNKG-IFHGDIKPENI .|||| . . ...... |.. | |. ... | |.|||..|| KHKNNRFNEHEISKIICDLVKTLNYIHKNCHIIHRDIKCDNI |
|||||||||
| Kinase | 23019.AA | CMGC | 237-258 | 42 | 3.1e-05 | 12.14 | In-house | 193-218 (513) | Show / Hide |
Range on Protein: 237-258 Range on HMM: 193-218/513 Sequence Identity: 42% (11 aa) LQ--YLLNKG--IFHGDIKPENIAIT | |. .. |.| |.||||| |. LKLKYCHSHWGNIIHRDLKPENILIN |
|||||||||