Gene 27042 (Tetrahymena)

27042

Species: Tetrahymena
Alias: TTHERM_00112280, n.27042, 1148, 8.m00302, PreTt27042, 27042
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
27042.AA Protein None 913 None Fasta, JSON
27042.kin_dom Protein Kinase Domain None 79 None Fasta, JSON
27042.NA RNA None 2742 None Fasta, JSON

Protein domain

Protein domains of 27042.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 27042.AA Ciliate-E1 59-88 31 0.118551 1.73 In-house 168-202 (202) Show / Hide 
Range on Protein: 59-88
Range on HMM: 168-202/202
Sequence Identity: 31% (11 aa)

QLYDYTHPYVLQEQKFT-----AEPQRYNLTSDKF
|   ||| |  .||...      ..| .|  || .
QYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY
Kinase 27042.AA Ciliate-E1 724-910 24 4.5e-21 65.62 In-house 1-202 (202) Show / Hide 
Range on Protein: 724-910
Range on HMM: 1-202/202
Sequence Identity: 24% (49 aa)

ANNWQQSQVEKQNIHSNSQIGSTEDIENSLKCDGYFDLQLIHKGTYSVLLEAYSQKQNKKVFEFLDYSKFITCIIVQEFCSQNLEEEIT---------NL
  |  .|.| |. . .|...   . |.|    . . ..| ..|  |...    ....  .......  . ..|||..|.|...|.....          .
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

KQQNKFFTNEDINTIFIHMINAINHIHSHKIIHCDIKPSNILKSQQSIYKICDFDLSSQLDQFQDSTSIMKGYTKYQCLQNKMN-------GIIIKNHLS
.|... || . .  |....| ... .|...|||.||||.|||...|..|..||| .|..|   |....  ||||.| . ....|          . |. |
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS

DEI
| .
DIY
Kinase 27042.AA Ciliate-B2 797-872 32 1.2e-20 45.21 In-house 77-152 (197) Show / Hide 
Range on Protein: 797-872
Range on HMM: 77-152/197
Sequence Identity: 32% (25 aa)

IIVQEFCSQNLEEEITNLKQQNKFFTNEDINTIFIHMINAINHIHSHKIIHCDIKPSNILKSQQSIYKICDFDLSS
... | |   |..|.  ...| | |.|. .  ..  .|..   ...  |.| ||||.|||..|.  |. |||  ||
VLIMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISS
Kinase 27042.AA CMGC 798-892 18 1.4e-18 56.79 In-house 132-287 (513) Show / Hide 
Range on Protein: 798-892
Range on HMM: 132-287/513
Sequence Identity: 18% (30 aa)

IVQEFCSQNLEEEITNLK------------------------QQNKFFTNEDINTIFIHMINAIN--HIHSHK--IIHCDIKPSNILKSQQSIY------
.| |.. ..| . | | .                        .. |.|.. .|  ..  ......  ..|||.  |||.|.||.||| ...  .      
LVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMW

--------------KICDFDLSSQLDQFQ----------------DSTSIMKGYTKYQC
              ||||| |. .... .                |. .... || | .
KSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDD-KPNRPYTHYVV
Kinase 27042.AA LKB 827-879 35 1.4e-16 45.83 In-house 107-159 (265) Show / Hide 
Range on Protein: 827-879
Range on HMM: 107-159/265
Sequence Identity: 35% (19 aa)

NTIFIHMINAINHIHSHKIIHCDIKPSNILKSQQSIYKICDFDLSSQLDQFQD
. .|.  . . . .|| ...| ||||.|.| .   . |||||    ||..||.
HFYFCQLCDGCEYLHSQRVVHKDIKPGNLLLTHDNTLKICDFGVAEQLHHFQR
Kinase 27042.AA C8 801-890 32 8.7e-16 51.36 In-house 100-197 (226) Show / Hide 
Range on Protein: 801-890
Range on HMM: 100-197/226
Sequence Identity: 32% (32 aa)

EFCSQNLEEEITNLKQQNKFFTNEDINTIFIHMINAINHIHSHKIIHCDIKPSNIL--KSQQSI--YKICDFDLSSQLDQFQDSTSIMK----GYTKY
| | |||..    ...... |..|.   | | ||  .| ||...|.| ||||.|.|   .|...   |.|||...||. . ...  . |    |  .|
ELCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAY
Kinase 27042.AA Ciliate-C8 800-874 31 4.6e-15 50.67 In-house 93-179 (238) Show / Hide 
Range on Protein: 800-874
Range on HMM: 93-179/238
Sequence Identity: 31% (27 aa)

QEFCSQN--LEEEITNLKQQNKFFTNEDINTIFIHMINAINHIHSHKIIHCDIKPSNIL----KSQQSIYKICD------FDLSSQL
.|.|.||  |.. ......... .....   | | ||  .| .| . |.| ||||.|.|    ...| . |.||      |...|||
MEKCQQNCNLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQL
Kinase 27042.AA ULK 796-868 28 5e-15 48.99 In-house 95-186 (329) Show / Hide 
Range on Protein: 796-868
Range on HMM: 95-186/329
Sequence Identity: 28% (26 aa)

CIIVQEFCSQ-NLEEEITNLKQ------QNKFFTNEDINTIFIHMINAINHIHSHKIIHCDIKPSNILKSQQS------------IYKICDF
. |..|.| . .||. | . |        .|... . .  .|.. .|.  ..|.|.|||.||||.||| .               ..||.||
IYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADF
Kinase 27042.AA ULK 798-868 29 1.2e-14 48.51 In-house 94-182 (324) Show / Hide 
Range on Protein: 798-868
Range on HMM: 94-182/324
Sequence Identity: 29% (26 aa)

IVQEFCSQ-NLEEEITNLKQ-----QNKFFTNEDINTIFIHMINAINHIHSHKIIHCDIKPSNILKSQQS------------IYKICDF
|..|.| . .||. | . |       .|... . .  .|.. .|.  ..|.|.|||.||||.||| .               ..||.||
IIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADF
Kinase 27042.AA Pkinase 798-888 25 2.7e-14 51.63 Pfam 77-172 (293) Show / Hide 
Range on Protein: 798-888
Range on HMM: 77-172/293
Sequence Identity: 25% (26 aa)

IVQEFCSQNLEEEITNL----KQQNKFF--TNEDINTIFIHMINAINHIHSHKIIHCDIKPSNILKSQQSIY----KICDFDLSSQLDQFQDSTSIMKGY
.|.|.|   |.  .        .... |  . ...  ..  .. .....||..|||.|.||.||| ...       ||||| |. |.|    . | |...
MVMEYCEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTF

T
.
C
Kinase 27042.AA Ciliate-E3 798-874 46 1.9e-12 35.38 In-house 81-156 (202) Show / Hide 
Range on Protein: 798-874
Range on HMM: 81-156/202
Sequence Identity: 46% (38 aa)

IVQEFCSQ-NLEEEITNLKQQNKFFTNEDINTIFIHMINAINHIHSHKIIHCDIKPSNILKSQQS---IYKICDFDLSSQL
||||.||  .|    . .|||||  | . |  |.| .|  .  ||. .||| ||||.||| ..     | ||||| .| ||
IVQEYCSNGDLY---HYIKQQNK--TQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGESKQL
Kinase 27042.AA Ciliate-A1 798-879 37 4.7e-12 37.26 In-house 78-156 (301) Show / Hide 
Range on Protein: 798-879
Range on HMM: 78-156/301
Sequence Identity: 37% (31 aa)

IVQEFCSQNLEEEITNLKQQNKFFTNEDINTIFIHMINAINHIHSHKIIHCDIKPSNILKSQQSIYKICDFDLSSQLDQFQD
|. |.|  ..     |.  ||..   |.|  |  ..|  .  ||.| |.| |.|| |||      .||||. .| || | ||
IIMEYCQYGN---LFNYCYQNDYMKKEEIYEICYQIIEGYADIHDHNILHRDLKPQNILIHFDDKWKICDLGMSKQLEQNQD
Kinase 27042.AA S_TKc 758-911 17 4.8e-08 -58.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 758-911
Range on HMM: 1-231/231
Sequence Identity: 17% (42 aa)

YFDLQLIHKGTYSVLLEAYSQK-----------------------QNKKVFEFLDYSKFITCIIVQEFCSQ---NLEEEITNLKQQNKF--FTNEDINTI
|  |..| ||....   ..  |                       . . .  ..|.       .| |.|..   .| . | . . . .   |.  ..  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

FIHMINAINHIHSHKIIHCDIKPSNILKSQQSIYKICDFDLSSQLDQFQDSTS----------IMKGYTK------------YQCLQNKM----------
.  ...|....|||.|||.|.||.||| ..    ||||| |. ||     .|           .. ||.|            | .|  .           
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFK

-----------NGIIIKN--------HLS-------DEII
           ...  |.         |        .. .
KIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase 27042.AA Ciliate-E3 758-784 22 0.005203 5.57 In-house 1-27 (202) Show / Hide 
Range on Protein: 758-784
Range on HMM: 1-27/202
Sequence Identity: 22% (6 aa)

YFDLQLIHKGTYSVLLEAYSQKQNKKV
|. .|.. .| ...   |... .|..|
YTVQQILGCGQFGRVYKAFDFQNNQDV
Kinase 27042.AA C8 758-784 25 0.01122 5.25 In-house 1-27 (226) Show / Hide 
Range on Protein: 758-784
Range on HMM: 1-27/226
Sequence Identity: 25% (7 aa)

YFDLQLIHKGTYSVLLEAYSQKQNKKV
  . |.. .| |.. |.|.  |.|...
FNNFQYLSFGAYGMVLKAKNVKDNREI
Kinase 27042.AA Ciliate-A1 758-783 42 0.015634 4.36 In-house 1-26 (301) Show / Hide 
Range on Protein: 758-783
Range on HMM: 1-26/301
Sequence Identity: 42% (11 aa)

YFDLQLIHKGTYSVLLEAYSQKQNKK
|   ||| || ..| . ||    .||
YHVVQLIDKGSFGVVMRAYDIQNQKK
Kinase 27042.AA Ciliate-C8 767-784 44 0.096652 2.44 In-house 1-18 (238) Show / Hide 
Range on Protein: 767-784
Range on HMM: 1-18/238
Sequence Identity: 44% (8 aa)

GTYSVLLEAYSQKQNKKV
| ... | |. .|||.||
GAFGMVLKAQNKKQNRKV
Kinase 27042.AA CMGC 758-784 19 0.10276 0.36 In-house 1-41 (513) Show / Hide 
Range on Protein: 758-784
Range on HMM: 1-41/513
Sequence Identity: 19% (8 aa)

YFDLQLIHKGTYSVLLEAYS--------------QKQNKKV
|  .. | .|||.|  ...                . |..|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIV