3618

Species: Tetrahymena
Alias: 3618, PreTt03618, 388.m00012, TTHERM_01435710, 1000
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
3618.AA Protein None 1171 None Fasta, JSON
3618.kin_dom Protein Kinase Domain None 125 None Fasta, JSON
3618.NA RNA None 3515 None Fasta, JSON

Protein domain

Protein domains of 3618.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 3618.AA Ciliate-B2 142-224 28 4.4e-11 22.21 In-house 63-148 (197) Show / Hide
Range on Protein: 142-224
Range on HMM: 63-148/197
Sequence Identity: 28% (25 aa)

VRIIEYSNIKKYDISYMIMELCEDNLESLIK----QNIKYSLQEAVNITMKLIGMLIDIHSSNLVHLSIEPRKILIDAENNFKLIGF
|..|..  |.. .|  .||| ||  |.. ..    | ...  |  ...   ||  || ... | .|| | |. ||.  ..|...  |
VKYIDHIQINE-TIDVLIMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDF

Kinase 3618.AA Ciliate-E1 112-271 17 5.2e-10 29.23 In-house 27-202 (202) Show / Hide
Range on Protein: 112-271
Range on HMM: 27-202/202
Sequence Identity: 17% (31 aa)

IKFIDQTEKQYKEQYEKLEA-FLQVQDTYSLVRIIEYSNIKKYDISYMIMELCEDNLESLIK-------------QNIKYSLQEAVNITMKLIGMLIDIH
|. ... ........ | .  .....   ... ||.|  |... |.. |.|.|...|.  ..             ...... |. ..|.. ||  ||..|
INCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELH

SSNLVHLSIEPRKILIDAENNFKLIGFPCQR--IKSSKKEKKMDFIDGDKYSTFKAP-QQLHNYEKVQQVSFISNVS
. |. |. | | .|||. ..|...  | . .  ......... .      |.. .    .. . .| |.... |.. 
QYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKINYKSDIY

Kinase 3618.AA Ciliate-A1 155-222 30 8.8e-08 22.51 In-house 75-143 (301) Show / Hide
Range on Protein: 155-222
Range on HMM: 75-143/301
Sequence Identity: 30% (21 aa)

ISYMIMELCE-DNLESLIKQNIKYSLQEAVNITMKLIGMLIDIHSSNLVHLSIEPRKILIDAENNFKLI
. ..||| |.  ||  ...||   .  | . | ...|  ..|||. | .|. . |  |||  .. .|..
CMFIIMEYCQYGNLFNYCYQNDYMKKEEIYEICYQIIEGYADIHDHNILHRDLKPQNILIHFDDKWKIC

S_TKc 3618.AA S_TKc 86-370 15 2.3e-07 -68.78 SMART 1-231 (231) Show / Hide
Range on Protein: 86-370
Range on HMM: 1-231/231
Sequence Identity: 15% (49 aa)

HRVIDPIDSEN--NVYKIEDIDTGLFFAIKFIDQTEKQYKEQYEKLEAFLQVQDTYSLVRIIEYSNIKKYDISYMIMELCED---NLESLIKQNIK----
 .....| .     |||  ...||  .||| |.        .  . |  .  ..   .|.....      |  ||.||.|.    .| ..||.. .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKKHHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--YSLQEAVNITMKLIGMLIDIHSSNLVHLSIEPRKILIDAENNFKLIGFPCQRIKSSKKEKKMDFIDGDKYSTFK------APQQLHNYEKVQQVSFIS
  ..  .|  ..  ..  |  .|| . .|  . |  ||.|   . |.. |   |.                 .||       ||  |             
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEVL-------------

NVSGDEFKIQSQNLSINSQKDGQEDFKE-EIDIFSMGLVILSVIG-VNINYRTADEIRTGNFNNIIDMNELNPLVSFVIHTMLQTEPQHRYSALKLQAEI
                         .   ..|. | | ..   .      .         . . ....    | .   |  .|| .|..|..| .. .. 
------------------------GYGKCKCDWWSCGCILYEMLCGYPPFP---------QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDE

-----LIYF
       .|
WDIKCHPWF

Kinase 3618.AA ULK 157-214 33 4.4e-05 13.79 In-house 96-164 (329) Show / Hide
Range on Protein: 157-214
Range on HMM: 96-164/329
Sequence Identity: 33% (23 aa)

YMIMELCED-NLESLIKQNIK----------YSLQEAVNITMKLIGMLIDIHSSNLVHLSIEPRKILID
|.|||.|.. .||..||.| |           | |||... . ..  . ..|. | .|  | |  |||.
YIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIH

Kinase 3618.AA Ciliate-E3 159-218 31 6e-05 11.69 In-house 82-141 (202) Show / Hide
Range on Protein: 159-218
Range on HMM: 82-141/202
Sequence Identity: 31% (19 aa)

IMELCED-NLESLIKQNIKYSLQEAVNITMKLIGMLIDIHSSNLVHLSIEPRKILIDAENN
..|.|.  .|   ||     ....   | ...|  .|.||. |. |  | |  ||.| .||
VQEYCSNGDLYHYIK-QQNKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNN

Kinase 3618.AA Ciliate-C3 196-224 37 6.3e-05 14.02 In-house 112-140 (140) Show / Hide
Range on Protein: 196-224
Range on HMM: 112-140/140
Sequence Identity: 37% (11 aa)

IHSSNLVHLSIEPRKILIDAENNFKLIGF
.|  |.||  | .. ||| .... |.| |
LHEHNIVHGDIKFSNILINSKDEIKIIDF

Kinase 3618.AA PLK 98-130 33 7.2e-05 11.91 In-house 15-47 (258) Show / Hide
Range on Protein: 98-130
Range on HMM: 15-47/258
Sequence Identity: 33% (11 aa)

VYKIEDIDTGLFFAIKFIDQTEKQYKEQYEKLE
.|...||.|.  .||| ...   |.. |.||..
CYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMK

Kinase 3618.AA NEK 342-368 29 0.000326 11.19 In-house 260-286 (286) Show / Hide
Range on Protein: 342-368
Range on HMM: 260-286/286
Sequence Identity: 29% (8 aa)

SFVIHTMLQTEPQHRYSALKLQAEILI
. .|. ||| .|..|.|. .. .  .|
QNLISQMLQKDPEQRPSCNQILEMPFI

Kinase 3618.AA CK1 157-203 31 0.000519 9.98 In-house 105-155 (339) Show / Hide
Range on Protein: 157-203
Range on HMM: 105-155/339
Sequence Identity: 31% (16 aa)

YMIMELCEDNLESLIK---Q-NIKYSLQEAVNITMKLIGMLIDIHSSNLVH
||.|.|.  |||.| |   . | | |.  ...| . ..  | ..|. . .|
YMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIH

Kinase 3618.AA Ciliate-E3 291-311 28 0.009315 4.77 In-house 182-202 (202) Show / Hide
Range on Protein: 291-311
Range on HMM: 182-202/202
Sequence Identity: 28% (6 aa)

QEDFKEEIDIFSMGLVILSVI
|  .. | |. |.| |.. ..
QQQISKESDYYSVGAVFCQLC

Kinase 3618.AA Ciliate-A1 298-369 20 0.229073 0.33 In-house 209-301 (301) Show / Hide
Range on Protein: 298-369
Range on HMM: 209-301/301
Sequence Identity: 20% (20 aa)

IDIFSMGLVILSVIG-----------VNINYRTADE------------IRTGNFNNII--DMNELNPLVSFVIHTMLQTEPQHRYSALKLQAEILIY
.|..|.|..|.   .           |||      .            |  ..|  .      ||. |    |  |.| ||. | |  ..  .  |.
SDMYSLGCIICFLCYKEDSHPYVGTIVNIFGNNMQNDQSIHFCKSVNAIKKIIFPPMQEPRFEELQNL----IFKMMQYEPNNRCSLQQCIDCLYIF

TPR 3618.AA TPR 527-560 14 1.077483 0.3 SMART 1-34 (34) Show / Hide
Range on Protein: 527-560
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

VDSLNSLATSLIYSYESQSSIQYLLAALNLRKVI
.. .. |. ..    . .  |...  || |    
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR 3618.AA TPR 570-603 26 0.000117 22.72 SMART 1-34 (34) Show / Hide
Range on Protein: 570-603
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AYTLSDLGEAYCQGKDYEQALQYHIQSLEMRKQL
| ... ||..| . .||..|...  ..||.  . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_1 3618.AA TPR_1 570-603 23 0.000717 17.5 Pfam 1-34 (34) Show / Hide
Range on Protein: 570-603
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

AYTLSDLGEAYCQGKDYEQALQYHIQSLEMRKQL
| ... || .| . ..|..|...  . ||.. . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

TPR_2 3618.AA TPR_2 570-603 26 0.010152 13.71 Pfam 1-34 (34) Show / Hide
Range on Protein: 570-603
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AYTLSDLGEAYCQGKDYEQALQYHIQSLEMRKQL
|. .  ||..| . .||..|..|  ..|.   . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN

TPR 3618.AA TPR 613-646 26 0.315401 4.99 SMART 1-34 (34) Show / Hide
Range on Protein: 613-646
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

ADSLFNLSKIYYLTNDMDQSIKLNTEGLQMSASI
|. ..||  .||. .| |. |.  .. |..  . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN

TPR_2 3618.AA TPR_2 613-635 34 1.912339 5.66 Pfam 1-23 (34) Show / Hide
Range on Protein: 613-635
Range on HMM: 1-23/34
Sequence Identity: 34% (8 aa)

ADSLFNLSKIYYLTNDMDQSIKL
|. ..|| ..||  .| |. |..
AEAWYNLGQCYYKQGDYDEAIEY

TPR_1 3618.AA TPR_1 613-646 23 7.794422 3.41 Pfam 1-34 (34) Show / Hide
Range on Protein: 613-646
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

ADSLFNLSKIYYLTNDMDQSIKLNTEGLQMSASI
|. ..||  .||  .. |. |.   . |..  . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN

LRR_RI 3618.AA LRR_RI 779-806 32 0.222142 3.15 SMART 1-28 (28) Show / Hide
Range on Protein: 779-806
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NLSNLTLQFPSNQIGAIGASDLGSGLAN
| | ..|.  .| .|. |.  | .||. 
NCSLRELWLSNNKLGDEGCRQLCEGLKH

LRR_RI 3618.AA LRR_RI 809-836 39 0.002586 16.8 SMART 1-28 (28) Show / Hide
Range on Protein: 809-836
Range on HMM: 1-28/28
Sequence Identity: 39% (11 aa)

NLSNLTLKLGQNQIGDEGASVLGSALAN
| | ..| |..| .||||. .| ..|. 
NCSLRELWLSNNKLGDEGCRQLCEGLKH

LRR_RI 3618.AA LRR_RI 839-866 46 0.015156 11.38 SMART 1-28 (28) Show / Hide
Range on Protein: 839-866
Range on HMM: 1-28/28
Sequence Identity: 46% (13 aa)

NLSNLTLDLCANQIGDEGASGLCSGLAN
| | ..|.|  | .||||.  ||.||. 
NCSLRELWLSNNKLGDEGCRQLCEGLKH

LRR_RI 3618.AA LRR_RI 916-943 32 0.068642 6.75 SMART 1-28 (28) Show / Hide
Range on Protein: 916-943
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NLSNLTLNLRFNQIGAMGASGLGQALAK
| | ..|.|. | .|. |.  | ..|. 
NCSLRELWLSNNKLGDEGCRQLCEGLKH

LRR_RI 3618.AA LRR_RI 946-973 39 0.008154 13.28 SMART 1-28 (28) Show / Hide
Range on Protein: 946-973
Range on HMM: 1-28/28
Sequence Identity: 39% (11 aa)

NLSNLTLKLGYNQIGDAGALGLGSGLAN
| | ..| |..| .||.|.  | .||. 
NCSLRELWLSNNKLGDEGCRQLCEGLKH

LRR_RI 3618.AA LRR_RI 976-1003 32 0.05812 7.26 SMART 1-28 (28) Show / Hide
Range on Protein: 976-1003
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NLSNLTLDLWFNQIGAMGASGLGQALAK
| | ..|.|. | .|. |.  | ..|. 
NCSLRELWLSNNKLGDEGCRQLCEGLKH

LRR_RI 3618.AA LRR_RI 1064-1091 32 0.583358 0.19 SMART 1-28 (28) Show / Hide
Range on Protein: 1064-1091
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NLSNLTLYLTANLIGAMGASGLGSALAN
| | ..|.|  | .|. |.  | ..|. 
NCSLRELWLSNNKLGDEGCRQLCEGLKH

LRR_RI 3618.AA LRR_RI 1094-1121 39 0.007203 13.66 SMART 1-28 (28) Show / Hide
Range on Protein: 1094-1121
Range on HMM: 1-28/28
Sequence Identity: 39% (11 aa)

NLSNLTLGLYGNQIGDEGASGLGSALAN
| | ..| | .| .||||.  | ..|. 
NCSLRELWLSNNKLGDEGCRQLCEGLKH

LRR_RI 3618.AA LRR_RI 1124-1151 42 0.017325 10.97 SMART 1-28 (28) Show / Hide
Range on Protein: 1124-1151
Range on HMM: 1-28/28
Sequence Identity: 42% (12 aa)

NLSNLTLDLDFNKIGDEGASGLGSALAK
| | ..|.|  ||.||||.  | ..|. 
NCSLRELWLSNNKLGDEGCRQLCEGLKH