Gene 5809 (Tetrahymena)

5809

Species: Tetrahymena
Alias: 3733.m00076, TTHERM_00579160, 1029, PreTt05809, 5809, 78.m00181
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-C3

Sequence

Name Sequence Type Origin Length Description Download
5809.AA Protein None 1621 None Fasta, JSON
5809.kin_dom Protein Kinase Domain None 45 None Fasta, JSON
5809.NA RNA None 4866 None Fasta, JSON

Protein domain

Protein domains of 5809.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 5809.AA Ciliate-C3 815-905 48 8.1e-25 85.38 In-house 54-140 (140) Show / Hide 
Range on Protein: 815-905
Range on HMM: 54-140/140
Sequence Identity: 48% (44 aa)

HQSDGQSFQLFLEYFESQNLLEYYQNKLENRKVFNYEKQNRIKIKKLKICIQILHAVEFLHQLNIVHGDIKLSNILISSKKGQRNIKLIDF
|| . . ||.|||||| | |...  |.... | ..  ..  .|..||.|  ||| |...||  ||||||||.||||| ||.   .||.|||
HQKNNKQFQIFLEYFEGQTLEKFI-NEIYDNKKYQDQNHKDLKLQKLQISKQILQAIDYLHEHNIVHGDIKFSNILINSKD---EIKIIDF
Kinase 5809.AA CAMKL 862-905 45 3.1e-15 44.93 In-house 131-173 (297) Show / Hide 
Range on Protein: 862-905
Range on HMM: 131-173/297
Sequence Identity: 45% (20 aa)

KICIQILHAVEFLHQLNIVHGDIKLSNILISSKKGQRNIKLIDF
..  ||..||...|...||| |||. |||..... . |||.|||
RYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDF
Kinase 5809.AA MARK 862-905 52 6.8e-15 45.28 In-house 108-150 (262) Show / Hide 
Range on Protein: 862-905
Range on HMM: 108-150/262
Sequence Identity: 52% (23 aa)

KICIQILHAVEFLHQLNIVHGDIKLSNILISSKKGQRNIKLIDF
.|. ||..||...|. |||| |||. |||| ... ..|||.|||
RIFRQIVSAVNYCHSKNIVHRDIKPENILIDENG-NHNIKIIDF
Kinase 5809.AA CAMK 862-905 34 8.2e-15 43.46 In-house 183-240 (425) Show / Hide 
Range on Protein: 862-905
Range on HMM: 183-240/425
Sequence Identity: 34% (20 aa)

KICIQILHAVEFLHQLNIVHGDIKLSNILISSKKGQR--------------NIKLIDF
..  ||. ||...|..|||| |.|. |||...... .              |||.|||
RYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF
Kinase 5809.AA AGC 866-905 40 1.1e-14 32.9 In-house 161-199 (395) Show / Hide 
Range on Protein: 866-905
Range on HMM: 161-199/395
Sequence Identity: 40% (17 aa)

QILHAVEFLHQ-LNIVHGD-IKLSNILISSKKGQRNIKLIDF
.|. |.|.||. ..|.| | .|. |||. ..    .||| ||
CIVLALEYLHSHMGIIHRDYLKPENILLDED---GHIKLTDF
Kinase 5809.AA CAMK-Unique 863-905 32 3.2e-14 43.15 In-house 162-217 (363) Show / Hide 
Range on Protein: 863-905
Range on HMM: 162-217/363
Sequence Identity: 32% (18 aa)

ICIQILHAVEFLHQLNIVHGDIKLSNILISSKKG-------------QRNIKLIDF
|. ..| ||...|...|||.|.|| ||....                . .|||.||
IMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDF
Kinase 5809.AA DAPK 866-905 43 3.9e-14 35.02 In-house 111-151 (264) Show / Hide 
Range on Protein: 866-905
Range on HMM: 111-151/264
Sequence Identity: 43% (18 aa)

QILHAVEFLHQLNIVHGDIKLSNILISSKKGQR-NIKLIDF
||| .| .||..||.| |.|  ||. .... .   ||.|||
QILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDF
Kinase 5809.AA Ciliate-E2 824-922 22 4.6e-14 44.64 In-house 111-253 (365) Show / Hide 
Range on Protein: 824-922
Range on HMM: 111-253/365
Sequence Identity: 22% (35 aa)

LFLEYFESQNLLEYYQNK-LENRKVFNYEKQNRIKIKKLK-ICIQILH---------------AVEFLHQLN-IVHGDIKLSNILISSKKGQRNIKLIDF
| .||.. ..|..| .|. .   . ..  . .....|. | |  |||                |.|.||. | |.| |||..|||.        ||.|||
LVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------IKIIDF

SESGF-------------MIEDTLGS------------------------TPGY
  | .             . . .  .                        ||||
GLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGY
Kinase 5809.AA Ciliate-E8 866-908 46 5.9e-14 39.98 In-house 97-138 (138) Show / Hide 
Range on Protein: 866-908
Range on HMM: 97-138/138
Sequence Identity: 46% (22 aa)

QILHAVEFLHQLNIVHGDIKLSNILISSKKGQR----NIKLIDFSES
||. |  .||..||.| |.|| |||.     ||    .||.|||  |
QIMDAFCYLHNNNIIHCDFKLNNILV-----QRNDDTKIKIIDFGFS
Kinase 5809.AA STE 862-905 42 9.8e-13 41.41 In-house 155-191 (359) Show / Hide 
Range on Protein: 862-905
Range on HMM: 155-191/359
Sequence Identity: 42% (19 aa)

KICIQILHA-VEFLHQLNIVHGDIKLSNILISSKKGQRNIKLIDF
.|| |||..  ..||...|.| ||| .|||.        .||.||
YICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDF
Kinase 5809.AA Pkinase 866-905 40 2.1e-09 34.33 Pfam 116-156 (293) Show / Hide 
Range on Protein: 866-905
Range on HMM: 116-156/293
Sequence Identity: 40% (17 aa)

QILHAVEFLHQLNIVHGDIKLSNILISSKKGQR--NIKLIDF
||| ..|..|. .|.| |.|..||||. ..|.    .|..||
QILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDF
S_TKc 5809.AA S_TKc 766-1015 16 3.1e-07 -70.78 SMART 1-231 (231) Show / Hide 
Range on Protein: 766-1015
Range on HMM: 1-231/231
Sequence Identity: 16% (47 aa)

YYEYIKIGKSQF-EIYKVSIEN-QGTFVMKQVPRDELNKKKFVEQQLREISHQSDGQSFQLFLEYFESQN------LLEYYQN---KLENRKVFNYEKQN
|    ||||  | . ||.   . .  . .|...          |. .|||.  .          ....         .||  .    |  . . .  . .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGL

R--IKIKKLKICIQILHAVEFLHQLNIVHGDIKLSNILISSKKGQRNIKLIDFSESGFMIEDTLGSTPGY---EEKNQFKKFLY-KCDC-----------
|  .     ... ||. |.|..|...|.| |.| .|||...     .||..||  . ..  .|.  || |   |      .. . |||            
RFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

------EDKYKDNQDKEKYIEKCYQSTLHKKQIKEKYKDQFSKHKDDYLQILFKQIMSLFNDQPYLRCSLEELIY--LMELQISIF
      .       . .. ..|.                          . .   |. ...  |  | .  |.    .   .   |
CGYPPFP-------QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc 5809.AA TyrKc 766-968 12 8.2e-05 -144.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 766-968
Range on HMM: 1-280/280
Sequence Identity: 12% (36 aa)

YYEYIKIGKSQF-EIYKVSIENQGTFVMKQVPRDELNKKKFVE--QQLREI--SHQ---------SDG-------QSFQLFLEYFESQNLLEYYQNKLEN
     |.|  .| |.||       .   | .  |   .. | .  . ....  .|.         ...       .   . .|| .  .|..| ... ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

RKVFNYEKQNRIKIK-KLKICIQILHAVEFLHQLNIVHGDIKLSNILISSKKGQRNIKLIDF-----SESG---------FMI-----ED----------
           .. | .|..|.||    |.||. |..| |.   |.|.....    .|  ||      ...          .      ..          
-----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

-------------------------TLGSTPGYE------EKNQFKKFLYKCDCEDKYKD---------NQDKEKYIEKCYQSTLHK----KQIKEKY
                         |.| .| ..      .  .  ... . .  .. ..          ..  . ...| .   ..    ..|.|. 
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 5809.AA Ciliate-C3 777-814 35 0.016933 5.31 In-house 1-37 (140) Show / Hide 
Range on Protein: 777-814
Range on HMM: 1-37/140
Sequence Identity: 35% (14 aa)

FEIYKVSI-ENQGTFVMKQVPRDELNKKKFVEQQLREIS
| . || . ||..  |  . |..|  .. ...||.||||
FIVKKVKLKENKDRKVALKQPQEE--QNDYSKQQMREIS