Gene 8761 (Tetrahymena)

8761

Species: Tetrahymena
Alias: TTHERM_00191100, 15.m00472, PreTt08761, 8761, 3697.m00183, 1011
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
8761.AA Protein None 513 None Fasta, JSON
8761.kin_dom Protein Kinase Domain None 484 None Fasta, JSON
8761.NA RNA None 1539 None Fasta, JSON

Protein domain

Protein domains of 8761.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 8761.AA S_TKc 8-491 13 5.2e-37 130.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-491
Range on HMM: 1-231/231
Sequence Identity: 13% (65 aa)

IKIIKSIGKGSYGEVFLCEDQL-GHKIALKAIKRNLLDDKFINSYKTELNALKKLQSAQNKSTLNDICYQADIENANLVGLLSKRSMSFDQEMCFLKEQN
 .|.. ||||..|.|..| .   |.. |.| ||                                                      .. .|.  ||.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------------------------------------EHIRREIQILKK--

SSVNCQDHQVNAKSNIIQFVKSIDNYPFQFNNKTYSCHALFIEYAKN--GCLGSYLESPKLTF----LPINILRRIAKQLFQGIQEMHSAHLVHRDIKED
              ||...  ....          ..  .. ||. .  | | .|... .       .|    |....|...... .|| . .|||.| .
-----------HHPNIVKLYDVFQD----------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPE

NIVFGEGYTLKLIDLSFAGRNDDEVCGTQKYISPEILKKEVQMLNCSSSQSNSVQQEQKVQQKELKFQRFA--KIDTFAAGVVLFRLATKIYPFGSASQF
|| . |  ..|..|  .| .  . .|||  |..||.|                                .   |.|  . |..|. ...   ||    | 
NILLDE--HIKICDFGLARQL-TTFCGTPWYMAPEVL-------------------------------GYGKCKCDWWSCGCILYEMLCGYPPFP---QM

DYKYKYIVSKQYDQFWSNVKFIVSSVNENNPDTQFNHFLQNRIQEETLQDLDTSSNSYDSNSEAEDNQEENENQSSSSQSNQENQTESQSSYNRKKSNIT
.  .| |.                                                                                            
QMMFKKIG--------------------------------------------------------------------------------------------

NRSSKKLLSYIKSKRAVSQVNFFLTPNEQAFFQQLMSEQDLNSIALSNQEINESYQQNIKEQIEQLKDLIQNLLSYEIDSRYGIQEALN-------HPFF
                                                               ...||.|...| .. . |... |||.       ||.|
--------------------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 8761.AA Ciliate-E2 149-491 13 3.4e-31 104.34 In-house 114-365 (365) Show / Hide 
Range on Protein: 149-491
Range on HMM: 114-365/365
Sequence Identity: 13% (58 aa)

EYAKNGCLGSYLESPKLTFLPI---------NILRRIAKQLFQ---------------GIQEMHSAH-LVHRDIKEDNIVFGEGYTLKLIDLSFAGRNDD
||.. | | .|... |. .. .         .  ..| ||..|               .....|| .  .||||| .||.|     .|.||. .. ..||
EYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDD

E-------------------------------------VCGTQKYISPEILKKEV---QMLNCSSSQSNSVQQEQKVQQKELKFQRFA-KIDTFAAGVVL
.                                     .|||  | .||||...    |                       |...   |.| ...||.|
DNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ----------------------QKQKGYDYKCDIWSLGVIL

FRLATKIYPFGSASQFDYKYKYIVSKQYDQFWSNVKFIVSSVNENNPDTQFNHFLQNRIQEETLQDLDTSSNSYDSNSEAEDNQEENENQSSSSQSNQEN
... .. .||                                                                                          
YEMLFGKPPF------------------------------------------------------------------------------------------

QTESQSSYNRKKSNITNRSSKKLLSYIKSKRAVSQVNFFLTPNEQAFFQQLMSEQDLN-SIALSNQE-INESYQQNIKEQIE---------QLKDLIQN-
                                                     .| ..  | ....| ... .| .| . ..         . ||||.. 
----------------------------------------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKF

---LLSYEIDSRYG-IQEALNHPFF
   .| .. . |.. ....||||.|
GKRMLQKDPEKRITGWEQILNHPWF
Kinase 8761.AA Ciliate-E2-Unclassified 8-491 11 3.3e-28 94.95 In-house 1-352 (352) Show / Hide 
Range on Protein: 8-491
Range on HMM: 1-352/352
Sequence Identity: 11% (63 aa)

IKIIKSIGKGSYGEVFLCEDQLGHKI-----ALKAIKRNLLDDKFINSYKTELNALKKLQ-SAQNKSTLNDICYQADIENANLVGLLSKRSMSFDQEMCF
 |||| ||.|..|.|..|..    ..     . |..... .  .. . .. |........ . |. .                                 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQR-K---------------------------------

LKEQNSSVNCQDHQVNAKSNIIQFVKSIDN---------------YPFQFNNKTYSCHALFIEYAKNGCLGSYLESPKL---------------TFLPIN
                           . |               . . .  ... .  .  ||...| |  |... |                  .. .
---------------------------Y-NKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQ

ILR-----RIAKQLFQGIQEMHSAH-LVHRDIKEDNIVFGEGY---TLKLIDLSFAG---------------------RNDDEVCGTQKYI----SPEIL
  .     ....|. ||.. .|. .  .||||| .||.| ..     .|.||....                       . . .|||  |.    .||.|
QAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL

KKEVQMLNCSSSQSNSVQQEQKVQQKELKFQRFAKIDTFAAGVVLFRLATKIYPFGSASQFD---YKYKYIVS-----KQYDQFWSNVKFIVSSVNENNP
... .    .                        |.| .. ||.|. . .  |||.. .. .   .... |        .|...  .  .. .. . .  
QGQNYDHSKA-----------------------YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQLYQNIKQKNIQFPKFPWQQ--

DTQFNHFLQNRIQEETLQDLDTSSNSYDSNSEAEDNQEENENQSSSSQSNQENQTESQSSYNRKKSNITNRSSKKLLSYIKSKRAVSQVNFFLTPNEQAF
                                                                                                    
----------------------------------------------------------------------------------------------------

FQQLMSEQDLNSIALSNQEINESYQQNIK-EQIEQLKDLIQNLLSYEIDSRYGIQEALNHPFF
                         ...  |... ..||.| .| . ...|......||||.|
-----------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 8761.AA Other-Unique 11-192 11 2.9e-19 62.43 In-house 1-249 (249) Show / Hide 
Range on Protein: 11-192
Range on HMM: 1-249/249
Sequence Identity: 11% (29 aa)

IKSIGKGSYGEVFLCEDQLGHKIALKAIKRNLLDDKFIN-------------------------------------------------------------
||.||||.||.|.........|.  | .| ... .. ..                                                             
IKDIGKGTYGRVYKQHHNKKKKYCAKKTKHHKI-HCMDMDNNKREQIYHYQIIHCIFYWTMNHCHLCFCYEHCPNMIFYIMYPWYHHHCECQCQCEHWMN

--SYKTELNALKKLQSAQNKSTLNDICYQADIENANLVG----------LLSKRSMSFDQEMCFLKEQNSSVNCQDHQVNAKSNIIQFVKSIDNYPFQFN
   . ..|. | . .   ... .| |..........  .           .... |.| .. . . ...... .... .. .... .....||.| |.. 
CCHMIHNLHHLHNNNHIHCDINPNNIWINQNNIHMCHNCGHNIPTIIIEHQHIKIMDFNNN-N-MMYFAPEF-SCRWCSPETFDYWPLGEKIDQYHFGCY

NKTYSCHALFIEYAKNGCLGSYLESPKLTFLPINILRRIAKQLFQGIQEMHSAHL
. ...|. .  .| .  .. . .|||| ....|.... . ...    .  ... .
HFHMNCQHWIFHYHDV-QHWPPHESPKDIHILICQCECCHQCM-VNPYQNPNCFY
Kinase 8761.AA Pkinase 121-292 17 1.1e-16 60.03 Pfam 61-212 (293) Show / Hide 
Range on Protein: 121-292
Range on HMM: 61-212/293
Sequence Identity: 17% (33 aa)

NIIQFVKSIDNYPFQFNNKTYSCHALFIEYAKNG----CLGSYLE---SPKLTFLPINILRRIAKQLFQGIQEMHSAHLVHRDIKEDNIVFGEGYTL---
||...  .  .       |.. .  .  ||. .|     | .|..   . ... .. . ......|...|.. .||   .|||.| .|| . . ...   
NIVRLYDWFED-------KDHIY--MVMEYCEGGLYVMDLFDYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDAC

-KLIDLSFA------GRNDDEVCGTQKYISPEILKKEVQMLNCSSSQSNSVQQEQKVQQKELKFQRFAKIDTFAAGVVLFRLATKIYPF
 |..|  .|      ..  . .|||  |..||...                                 |.| ...|..|. ....  ||
VKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIR--------------------------GGQYYGPKVDMWSCGCILYEMLCGRPPF
Kinase 8761.AA CAMK 174-292 21 2e-13 38.94 In-house 182-334 (425) Show / Hide 
Range on Protein: 174-292
Range on HMM: 182-334/425
Sequence Identity: 21% (36 aa)

RRIAKQLFQGIQEMHSAHLVHRDIKEDNIVF-GEG----------------YTLKLIDLSFAGRNDD-----------------------------EVCG
||. .|. .... .|| . ||||.| .|| .   .                ...|.||  || . |.                             ..||
RRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG

TQKYIS-PEILKK--EVQMLNCSSSQSNSVQQEQKVQQKELKFQRFAKIDTFAAGVVLFRLATKIYPF
|  |.. ||.|..    .| | . .              | |     |.|  ..||.|. . .  .||
TPEYMAAPEVLNGKGHCNMQN-A-T-------------DEEKPYYGPKCDMWSCGVILYIMLCGYPPF
Kinase 8761.AA STE 146-240 20 1.7e-11 37.02 In-house 114-237 (359) Show / Hide 
Range on Protein: 146-240
Range on HMM: 114-237/359
Sequence Identity: 20% (27 aa)

LFIEYAKNGCLGSYLE---SPKL---------TFLPINILRRIAKQLFQG-IQEMHSAHLVHRDIKEDNIVFGEGYTLKLIDLSFAGRNDD---------
.. ||  .|.| . ..   ...          ...| .....|..|. .|  .  || | .||||| .|| .      ||.|  ..|. .|         
ICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNN

-------------EVCGTQKYISPEILKKE
              ..||. . .||.....
IIDCIETMQQKRNTFVGTP-WMAPEVIQQN
Kinase 8761.AA CAMKL 174-240 30 2.3e-11 32.37 In-house 130-210 (297) Show / Hide 
Range on Protein: 174-240
Range on HMM: 130-210/297
Sequence Identity: 30% (25 aa)

RRIAKQLFQGIQEMHSAHLVHRDIKEDNIVFGEGY--TLKLIDLSFA----------GRNDDEVCGTQKYISPEILKK--E
||. .|.  ... .|| . |||||| .|| . |    ..|.||  |.          |.  .. ||.  | .|||...  .
RRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNK
Kinase 8761.AA AGC 179-237 16 1.1e-10 22.32 In-house 161-279 (395) Show / Hide 
Range on Protein: 179-237
Range on HMM: 161-279/395
Sequence Identity: 16% (20 aa)

QLFQGIQEMHS-AHLVHRD-IKEDNIVFGEGYTLKLIDLSFAGRNDDE----------------------------------------------------
..  ... .||  . .||| .| .||.. |   .|| |  .. .. ..                                                    
CIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRD

----VCG--TQKYISPEIL
     ||  |  |..||||
RTWTFCGPCTPEYMAPEIL
Kinase 8761.AA ULK 146-240 24 1.5e-10 33.68 In-house 94-226 (324) Show / Hide 
Range on Protein: 146-240
Range on HMM: 94-226/324
Sequence Identity: 24% (33 aa)

LFIEYAKNGCLGSYLESPKL-------TFLPINILRRIAKQLFQGIQEMHSAHLVHRDIKEDNIVFGEG------------YTLKLIDLSFAGRNDD---
.. ||   | | .|..  |         .|. .. . . ||. .| .|.|.   .||||| .||   .|            ..||. |  ||   |.   
IIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNM

--EVC----------GTQKYISPEILK----KE
   .|          ||  | .|.||.    ..
EQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQK
Kinase 8761.AA CMGC 159-218 15 4.5e-10 28.34 In-house 144-251 (513) Show / Hide 
Range on Protein: 159-218
Range on HMM: 144-251/513
Sequence Identity: 15% (17 aa)

YLESPK--------------------------LTFLPINILRRIAKQLFQGIQ--EMHSAH--LVHRDIKEDNIVFGEG--------------------Y
|... .                            ...|   | ...|...|.    .||.    .|||.|  || . .                     .
YIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNG

TLKLIDLSFA
.||..|  .|
RLKICDFGLA
Kinase 8761.AA AGC 8-39 35 9e-10 19.92 In-house 1-39 (395) Show / Hide 
Range on Protein: 8-39
Range on HMM: 1-39/395
Sequence Identity: 35% (14 aa)

IKIIKSIGKGSYGEVFLCEDQLGH------KI-ALKAIK
 ...| |||||.|.|.|...  |.      |. |.| .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLK
Kinase 8761.AA CAMK 462-491 36 3.1e-09 25.16 In-house 396-425 (425) Show / Hide 
Range on Protein: 462-491
Range on HMM: 396-425/425
Sequence Identity: 36% (11 aa)

EQLKDLIQNLLSYEIDSRYGIQEALNHPFF
.. ||||...| .. . |. |...||||..
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 8761.AA AGC 462-491 32 4.6e-09 18.05 In-house 356-395 (395) Show / Hide 
Range on Protein: 462-491
Range on HMM: 356-395/395
Sequence Identity: 32% (13 aa)

EQLKDLIQNLLSYEIDSRYG----------IQEALNHPFF
...||||. ||  . . | |          ..|  |||.|
PEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 8761.AA CAMK 13-62 21 6.1e-09 24.19 In-house 1-89 (425) Show / Hide 
Range on Protein: 13-62
Range on HMM: 1-89/425
Sequence Identity: 21% (19 aa)

SIGKGSYGEVFLCEDQ-LG------------HKIALKAIKRNLLDDKF--------------------------INSYKTELNALKKLQ
 .|.||.|.|.||..   .            .| | | |... |.||                             . . |.. .||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQ
Kinase 8761.AA CAMKL 9-62 26 7.3e-09 24.26 In-house 2-70 (297) Show / Hide 
Range on Protein: 9-62
Range on HMM: 2-70/297
Sequence Identity: 26% (18 aa)

KIIKSIGKGSYGEVFLCED-QL-GHKIALKAIKRNLLD-DKFINSY------------KTELNALKKLQ
.|.| .||||.|.| |... .. |.| | | |... .  | ....             . | . .|.|.
RIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN
Kinase 8761.AA CMGC 8-75 22 2.4e-08 22.56 In-house 1-108 (513) Show / Hide 
Range on Protein: 8-75
Range on HMM: 1-108/513
Sequence Identity: 22% (25 aa)

IKIIKSIGKGSYGEVFLCEDQL---------------GHKIALKAIKRNLLDDK----------FINSYKTELNALKKLQ----------------SAQN
 .||| ||.|.||.|. | |..               . ..|.| ||..  ..           |  .   |.  ||.|.                   |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

KSTLNDICY
  .| ||.|
IVKLYDIFY
Kinase 8761.AA CMGC 446-491 21 9.1e-08 20.62 In-house 453-513 (513) Show / Hide 
Range on Protein: 446-491
Range on HMM: 453-513/513
Sequence Identity: 21% (14 aa)

NQEINESYQQNIKEQI--------------------EQLKDLIQNLLSYEIDSRYGIQEALNHPFF
| . .  .. . .. |                    .|. ||....| |. | |  ...||.||.|
N-NKK--AMVF-NW-IYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 8761.AA DYRK 460-491 34 3.5e-07 23.18 In-house 289-320 (320) Show / Hide 
Range on Protein: 460-491
Range on HMM: 289-320/320
Sequence Identity: 34% (11 aa)

QIEQLKDLIQNLLSYEIDSRYGIQEALNHPFF
. .|.||.|. .| .. ..|   ..||.||.|
DDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase 8761.AA STE 8-63 15 8.3e-07 20.2 In-house 1-89 (359) Show / Hide 
Range on Protein: 8-63
Range on HMM: 1-89/359
Sequence Identity: 15% (14 aa)

IKIIKSIGKGSYGEVFLCEDQ----------------LGHKIALKAIK-----------RNLLDD------KFINSYKTELNALKKLQ--S
 ..|. ||||..|.|... .                  |  .| | ..            |   .      . ..... |.. .||..  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMH
Kinase 8761.AA DYRK 8-41 40 9.1e-07 21.62 In-house 1-35 (320) Show / Hide 
Range on Protein: 8-41
Range on HMM: 1-35/320
Sequence Identity: 40% (14 aa)

IKIIKSIGKGSYGEVFLCEDQLGH-KIALKAIKRN
 .|.. |||||.| |. |.|. .. ..|.| |..|
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNN
Kinase 8761.AA Pkinase 8-63 27 2e-06 24.04 Pfam 1-59 (293) Show / Hide 
Range on Protein: 8-63
Range on HMM: 1-59/293
Sequence Identity: 27% (16 aa)

IKIIKSIGKGSYGEVFLCEDQLGHK-IALKAIKRNLLDDKFINSYKT--ELNALKKLQS
..|.. ||.||.|.|..| ..   |  |.| ||.   ....  .     |.  .|.|..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNH
Kinase 8761.AA ULK 8-61 22 1.1e-05 16.25 In-house 1-67 (324) Show / Hide 
Range on Protein: 8-61
Range on HMM: 1-67/324
Sequence Identity: 22% (15 aa)

IKIIKSIGKGSYG-EVFLC--EDQL--GHKIALKAIKRNLLDDKFIN--------SYKTELNALKKL
. ... .||||.|  |.    ...   . ..| | | .. . .|  .        . | | . .|||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKL
Kinase 8761.AA CAMKL 463-491 31 1.6e-05 13.45 In-house 269-297 (297) Show / Hide 
Range on Protein: 463-491
Range on HMM: 269-297/297
Sequence Identity: 31% (9 aa)

QLKDLIQNLLSYEIDSRYGIQEALNHPFF
...|||. .|    . |. |.. .|||..
DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 8761.AA DYRK 167-214 28 2e-05 16.51 In-house 99-150 (320) Show / Hide 
Range on Protein: 167-214
Range on HMM: 99-150/320
Sequence Identity: 28% (15 aa)

FLPINILRRIAKQLFQGIQEMHSA-HLVHRDIKEDNIVFGEG---YTLKLID
|...|  |..|.|.....  .|.   ..| |.| .||.  .    .|.|.||
FFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVID
Kinase 8761.AA Ciliate-E2 8-71 18 2.4e-05 14.32 In-house 1-90 (365) Show / Hide 
Range on Protein: 8-71
Range on HMM: 1-90/365
Sequence Identity: 18% (17 aa)

IKIIKSIGKGSYGEVFLCED-QLGHKIALKAIKRNLL--------DDKFI---NSY-KTELNALKKLQSAQ--------------NKSTLN
.|.|| ||.|..| |..|.. . ....|.| |. ...        ....|   ... | .....|. ..                ....||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLN
Kinase 8761.AA Pkinase 464-491 32 2.5e-05 19.94 Pfam 266-293 (293) Show / Hide 
Range on Protein: 464-491
Range on HMM: 266-293/293
Sequence Identity: 32% (9 aa)

LKDLIQNLLSYEIDSRYGIQEALNHPFF
.||.| ..| .   .|......|.||.|
CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 8761.AA TyrKc 8-283 14 5.6e-05 -142.15 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-283
Range on HMM: 1-280/280
Sequence Identity: 14% (52 aa)

IKIIKSIGKGSYGEVFLCEDQLGHKIALKAIKRNLLDDKFINSYKTELNALKKLQSAQNKSTLNDICYQADIENANLVGLLSKRSMSFDQEMCFLKEQNS
|. .| .| | .|||....                           .  | |.|..                             . | .|.  ...   
ITLGKKLGEGAFGEVYKGTWK-------------------------IQVAVKMLKEDA--------------------------REDFMREARIMCK---

SV--NCQDHQVNAKSNIIQF--VKSID--NYPFQFNNKTY---SCHALFIEYAKNGCLGSYLESPKLTFLPINILRRIAKQLFQGIQEMHSAHLVHRDIK
 .  . .        ||...  | . .  |         .     . .  ||...|.| .|| ... . |.   |  .. |  .| .  || ...|||. 
-LGGHHP--------NIVRLYGVCTQQGRN---------FMYIEPLMIVMEYMPHGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLA

EDNIVFGEGYTLKLID--LSFAGRND-------DEVC-----GTQ-----KYISPEILKKE-----------------------VQMLN-----CSSSQ-
  |.  ||..| |  |  || .. .|       |        |.      .  .|| ...                            .     .| .. 
ARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEV

SNSVQQEQKVQQKEL--------KFQRFAKI------D------TFAAGVVLF
 . |.|     | .           .   .|             ||.. . .|
IEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 8761.AA ULK 429-491 24 0.000316 10.97 In-house 253-324 (324) Show / Hide 
Range on Protein: 429-491
Range on HMM: 253-324/324
Sequence Identity: 24% (18 aa)

FFQQLMSEQDLNSIALSNQ-------EINESYQQNIKE---QI-EQLKDLIQNLLSYEIDSRYGIQEALNHPFF
| .  .....   . | |.       . |.  | ....   .| ...||||. .| |. . |  ..| .|||.|
FSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 8761.AA Pkinase_Tyr 8-26 36 0.002192 12.09 Pfam 1-19 (270) Show / Hide 
Range on Protein: 8-26
Range on HMM: 1-19/270
Sequence Identity: 36% (7 aa)

IKIIKSIGKGSYGEVFLCE
|...| .|.|..|||....
ITFGKKLGEGAFGEVYKGT
Kinase 8761.AA Pkinase_Tyr 149-197 27 0.003164 11.55 Pfam 87-137 (270) Show / Hide 
Range on Protein: 149-197
Range on HMM: 87-137/270
Sequence Identity: 27% (14 aa)

EYAKNGCLGSYLESP--KLTFLPINILRRIAKQLFQGIQEMHSAHLVHRDI
||...|.| .|| ..      |..  |  .. |  .| .  .| ...|||.
EYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 8761.AA STE 462-491 28 0.006806 6.2 In-house 328-359 (359) Show / Hide 
Range on Protein: 462-491
Range on HMM: 328-359/359
Sequence Identity: 28% (9 aa)

EQLKDLIQNLLSYEIDSRYGIQEALN--HPFF
. .|| |.. | .. . |   .. |.  |||.
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI