Gene 10617 (Tetrahymena)

10617

Species: Tetrahymena
Alias: 92.m00159, PreTt10617, TTHERM_00643470, 10617, 1189
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
10617.AA Protein None 888 None Fasta, JSON
10617.kin_dom Protein Kinase Domain None 368 None Fasta, JSON
10617.NA RNA None 2664 None Fasta, JSON

Protein domain

Protein domains of 10617.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 10617.AA Ciliate-B2 311-496 35 3.6e-70 164.22 In-house 1-197 (197) Show / Hide 
Range on Protein: 311-496
Range on HMM: 1-197/197
Sequence Identity: 35% (71 aa)

YQTKKIIAVSGEGVIFDGIQNQEITKQQKEVVIKVQFNEVDIDLLKL---LDIQQSFTQYEYNIVNLLDFV-VQQNFQILVLEKCEMDLSQKLKNIKNDT
|   |.|.  |.|.|..|    .. .. .....|..||  | |   .   . | ..| .|. |.| ..|.. .... ..|..|||| .| | |. |.   
YYLCKYINKGGCGFICEGYK-KHSIREYQDLAFKIYFNKQDCDKEEIQHEIKIMKMF-EYNINVVKYIDHIQINETIDVLIMEKCECSLKQELQKIQKQQ

--FEELKLLNMIFDLLDGLITFQLYYIIHCDIKPSNILVNQQERYFYTDFGISLIALPNQNQIQYSYTAPFASPEQLNKQ-------CICYKTDVYSLG
  |.. ||..|||.|.|||| | .| |.| ||||.|||. |.. | |.||||| |   ||..     |  .|||||...         | .. |.||.|
KCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKKDNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase 10617.AA Ciliate-E1 317-493 28 1.1e-42 136.7 In-house 1-202 (202) Show / Hide 
Range on Protein: 317-493
Range on HMM: 1-202/202
Sequence Identity: 28% (58 aa)

IAVSGEGVIFDGIQNQEITKQQKEVVIKVQFNEVDIDLLKLLDIQQSFTQYEY---NIVNLLDFVV-QQN-FQILVLEKCEMDLSQKLK-----------
|. ......|...|.. ...| ....|...||..........  .... .      .|....|.   .|| ..|...|.|.. | ..|.           
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

NIKNDTFEELKLLNMIFDLLDGLITFQLYYIIHCDIKPSNILVNQQERYFYTDFGISL--IALPNQNQIQYSYTAPFASPEQLN--------KQCICYKT
. ..  | .......||.|.|||| .. | |||.||||.|||.|.|..| |.|||||.  .   ||.. .  ||  ...|||.|        .| | ||.
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS

DVY
|.|
DIY
Kinase 10617.AA S_TKc 129-545 14 2.8e-14 32.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 129-545
Range on HMM: 1-231/231
Sequence Identity: 14% (63 aa)

YEIQDLISKGEIGFVFKAKNLKTQEEVAIKIINYQQFNYCDIDDLLEAQSWNFVNLTLIAKAYKSKFFDRNRSERIPQEIPDFMICSNSDQRLEITEIKE
||| ..| ||  | |.|... ||...||||||.                                                                   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------

MFFQKIKNINFDFISDMNFNIILTLQTQIEINIIESKNESKKLRNKSSQGLMKNHQYKSLQRLLKNLEDNMIDIISKLNSRNYQTKKIIAVSGEGVIFDG
                                                                                                    
----------------------------------------------------------------------------------------------------

IQNQEITKQQKEVVIKVQFNEVDIDLLKLLDIQQSFTQYEYNIVNLLDFVVQQNFQILVLEKCEM---DLSQKLKNIKNDT----FEELKLLNMIFDLLD
                 .  .  |..||             |||.|.|. .  ..  .|.| |.    || . .|. .       | |     ..  ...
-----------------EHIRREIQILKK---------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICC

GLITFQLYYIIHCDIKPSNILVNQQERYFYTDFGISLIALPNQNQIQYSYTAPFASPEQLNKQCICY-KTDVYSLG---------KT----FNTIFDKVN
.|       |||.|.||.|||...  .   .|||.. .         .  |  . .|| |      . | |..|.|         ..     ...|.|. 
ALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG

EQLPKYIADFKILINTYMLDNEPSKRKNCLELHE-------MFFQ
        ..| .|.  .|. .|.||  . |. .       . . 
------SPEAKDFIR-KCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 10617.AA Ciliate-E2-Unclassified 370-496 25 1.8e-11 36.04 In-house 82-257 (352) Show / Hide 
Range on Protein: 370-496
Range on HMM: 82-257/352
Sequence Identity: 25% (44 aa)

NIVNLLDFVVQQNFQILVLEKCEM-DLSQKLKNIKN---------------DTFEELKLL-----NMIFDLLDGL-ITFQLYYIIHCDIKPSNILVNQQE
.||....   ...  ..|.|.||  ||.| .|. |.                 |.| . .     ...  .|.||    .   ||| ||||.|||.... 
FIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNG

---RYFYTDFGISLIALPN--------------QNQIQYSY--TAPFA----SPEQLNKQCIC----YKTDVYSLG
   .   .|||||     |              ..|....   |  .     .|| | .|       || |..|||
KNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLG
Kinase 10617.AA CMGC 330-472 17 3.2e-11 32.17 In-house 31-283 (513) Show / Hide 
Range on Protein: 330-472
Range on HMM: 31-283/513
Sequence Identity: 17% (45 aa)

QNQEITKQQKEVVIKVQFNE--------------------VDIDLLKLL----DIQQ------SFTQYEYNIVNLLDFVVQQNFQ---------------
| .. .. ...| ||  .|.                      | .|| |    |. .      .. . . |||.|.|...  | .               
Q-AHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFN

--ILVLEKCEMDLSQKLKNIKND-------TFEELK------------LLNMI------FDLLDGLI--TFQLYY--IIHCDIKPSNILVNQQERY----
   || | ...|| | .|| ..|        ..| .              ...      . .| ||           |||.|.||.|||.|.. ..    
HLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRM

----------------FYTDFGISLIALPNQNQIQYS-----------------YT
                   ||| . .  |........                 ||
MWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYT
Kinase 10617.AA ULK 368-496 22 3.5e-11 35.39 In-house 74-243 (329) Show / Hide 
Range on Protein: 368-496
Range on HMM: 74-243/329
Sequence Identity: 22% (38 aa)

EY---NIVNLLDFVVQQ--NFQILVLEKCEM-DLSQKLKNIKN--------DTFEELKLLNMIFDLLDGLITFQLYYIIHCDIKPSNILVNQQE------
..   ||| |.|.   .  |   ...| |.  ||.| .|. |.         ...| . .. . ..| |.   .   |||.||||.|||..         
KNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSK

------RYFYTDFGISLIALPN--QNQIQYSYT--------APFASPEQLN----KQCIC-YKTDVYSLG
      ..  .||| .     .  ..|. ....          . .|. |.    ..  . ||.|..|||
KVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLG
Kinase 10617.AA Ciliate-E1 135-242 19 4.2e-11 32.83 In-house 138-256 (202) Show / Hide 
Range on Protein: 135-242
Range on HMM: 138-256/202
Sequence Identity: 19% (23 aa)

ISKGEIGFVFKAKNLKTQEEVAIKIINYQQFNYCDIDDLLEAQSWNFVNLTLIAKAYKSKFFDRNRSERIPQEIPDFMICSNSDQRLEI-----------
|..|  ..|||||. ...... ...|   .||| ..... | .  . .   .. . |  ...|  ... .  .|  |. |. |...              
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

-TEIKEMFFQKIKNINFDFI
 .. ... ||.. .| |. |
QQNQNQFTFQQKMQIIFQLI
Kinase 10617.AA C8 388-499 24 3.9e-10 31.47 In-house 99-226 (226) Show / Hide 
Range on Protein: 388-499
Range on HMM: 99-226/226
Sequence Identity: 24% (31 aa)

LEKCEMDLSQKLKNIKNDTFE--ELKLLNMIFDLLDGLITFQLYYIIHCDIKPSNILVNQQERYF----YTDFGISLIALPNQNQIQYSY-----TAPFA
.| ||  | |  .  .|   .  . . ...   ..||. . ..  |.| ||||.|.||  .. |       |||..     |...||        |  . 
MELCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYF

SPEQLNK-----QCICYKTDVYSLGKTF
 ||...|     .    . |..|.|   
APEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 10617.AA Pkinase 370-496 26 8.8e-10 35.67 Pfam 61-199 (293) Show / Hide 
Range on Protein: 370-496
Range on HMM: 61-199/293
Sequence Identity: 26% (37 aa)

NIVNLLDFVVQQNFQILVLEKCEM-----DLSQKLK---NIKNDTFEELKLLNMIFDLLDGLITFQLYYIIHCDIKPSNILVNQQERY----FYTDFGIS
||| |.|..   .   .|.| ||.     ||.  ..   . .   |.|  . ...  .| ||       |||.|.||.|||....         .|||..
NIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA

LI--ALPNQNQIQYSYTAPFASPEQLN-KQCICYKTDVYSLG
      .|.    .  | ....|| ..  | . .| |..|.|
KQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG
Kinase 10617.AA Ciliate-E3 431-503 36 1.5e-09 26.25 In-house 124-202 (202) Show / Hide 
Range on Protein: 431-503
Range on HMM: 124-202/202
Sequence Identity: 36% (29 aa)

IIHCDIKPSNILVNQQE---RYFYTDFGISLIALPNQ--NQIQ-YSYTAPFASPEQLNKQCICYKTDVYSLGKTFNTIF
||| ||||.|||| . .        ||| |     |   .. |    |  .|.|||. .| |    | ||.|  |  . 
IIHSDIKPDNILVDKNNNQLIIKICDFGESKQLRKNKGHTHTQYQGWTPFYAAPEQNDQQQISKESDYYSVGAVFCQLC
Kinase 10617.AA ULK 370-496 23 3e-09 29.05 In-house 74-239 (324) Show / Hide 
Range on Protein: 370-496
Range on HMM: 74-239/324
Sequence Identity: 23% (39 aa)

N--IVNLLDFVVQQ--NFQILVLEKCEM-DLSQKLKNIKN-------DTFEELKLLNMIFDLLDGLITFQLYYIIHCDIKPSNILVNQQE----------
|  || |.|.   .  |.  ...| |.  ||.| .|. |.        ...| . .. . ... |.   .   |||.||||.|||..             
NHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP

--RYFYTDFGISLIALPNQNQIQYSYTAP----------FASPEQLN----KQCIC-YKTDVYSLG
  ..  .||| . .   |. . |  .|.           . .|. |.    ..  . ||.|..|||
NGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLG
Kinase 10617.AA DYRK 129-161 54 8.8e-09 29.24 In-house 1-33 (320) Show / Hide 
Range on Protein: 129-161
Range on HMM: 1-33/320
Sequence Identity: 54% (18 aa)

YEIQDLISKGEIGFVFKAKNLKTQEEVAIKIIN
||| . | ||  | |.|... ||.| ||||||.
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIR
Kinase 10617.AA DYRK2 129-165 47 1e-08 24.15 In-house 1-38 (318) Show / Hide 
Range on Protein: 129-165
Range on HMM: 1-38/318
Sequence Identity: 47% (18 aa)

YEIQDLISKGEIGFVFKAKNLKTQEEVAIKII-NYQQF
|||   |.||  | |.|.   ||.. ||||.| | . |
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRF
Kinase 10617.AA DYRK2 369-448 30 1.4e-08 23.71 In-house 61-140 (318) Show / Hide 
Range on Protein: 369-448
Range on HMM: 61-140/318
Sequence Identity: 30% (24 aa)

YNIVNLLDFVVQQNFQILVLEKCEMDLSQKLKNIKNDTFEELKLLNMIFDLLDGLITFQLYYIIHCDIKPSNILVNQQER
.|.| .||...  |. ....|   |.|   .|. .   |       ... .| .|   .   ||||| || ||| .|. |
MNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNR
Kinase 10617.AA CMGC 129-160 32 8.6e-08 20.7 In-house 1-46 (513) Show / Hide 
Range on Protein: 129-160
Range on HMM: 1-46/513
Sequence Identity: 32% (15 aa)

YEIQDLISKGEIGFVFKAKN--------------LKTQEEVAIKII
||| . | .|  | |.|...               .|.|.||||.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKI
Kinase 10617.AA ULK 129-166 33 1.1e-07 23.46 In-house 1-42 (324) Show / Hide 
Range on Protein: 129-166
Range on HMM: 1-42/324
Sequence Identity: 33% (14 aa)

YEIQDLISKGEIG-FVFKAKNLKT---QEEVAIKIINYQQFN
|.. . . ||  |  |.|..| ||   .. ||.|.|. ...|
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMN
Kinase 10617.AA Ciliate-E3 129-160 37 1.2e-07 20.28 In-house 1-32 (202) Show / Hide 
Range on Protein: 129-160
Range on HMM: 1-32/202
Sequence Identity: 37% (12 aa)

YEIQDLISKGEIGFVFKAKNLKTQEEVAIKII
| .|... .|. | |.|| .     .|||| |
YTVQQILGCGQFGRVYKAFDFQNNQDVAIKAI
Kinase 10617.AA ULK 129-166 38 1e-06 19.56 In-house 1-42 (329) Show / Hide 
Range on Protein: 129-166
Range on HMM: 1-42/329
Sequence Identity: 38% (16 aa)

YEIQDLISKGEIGFVFKAKNLKT----QEEVAIKIINYQQFN
|.. . . ||  | |.|..| ||    .| ||.|.|  |..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMN
Kinase 10617.AA DYRK 366-449 29 2e-06 20.64 In-house 58-144 (320) Show / Hide 
Range on Protein: 366-449
Range on HMM: 58-144/320
Sequence Identity: 29% (26 aa)

QYEYNIVNLLDFVVQQNFQILVLEKCEMDLSQKLKNIKNDTFEELKLL-NMIFDLLDGLITFQLY-YIIHCDIKPSNILVNQQ-ERY
...|..|...|. . .|.  .| |  .|.| . ||| . . |  |.|   ... .|..|   .    |||||.|| ||...|.  ..
DDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKS
Kinase 10617.AA Pkinase 129-163 37 1e-05 21.26 Pfam 1-35 (293) Show / Hide 
Range on Protein: 129-163
Range on HMM: 1-35/293
Sequence Identity: 37% (13 aa)

YEIQDLISKGEIGFVFKAKNLKTQEEVAIKIINYQ
|.|   | .|  | |.|... .|...||.|||...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR
Kinase 10617.AA Ciliate-E2-Unclassified 129-164 29 2e-05 14.8 In-house 1-40 (352) Show / Hide 
Range on Protein: 129-164
Range on HMM: 1-40/352
Sequence Identity: 29% (12 aa)

YEIQDLISKGEIGFVFKAKNLKTQEEV-----AIKIINYQQ
|.|.  | .|  | |.|... |.. ..     ..||..| |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQ
Kinase 10617.AA C8 126-164 33 2.3e-05 14.72 In-house 1-36 (226) Show / Hide 
Range on Protein: 126-164
Range on HMM: 1-36/226
Sequence Identity: 33% (13 aa)

NQNYEIQDLISKGEIGFVFKAKNLKTQEEVAIKIINYQQ
 .|...   .|.|  | | ||||.| . |...|.  .|.
FNNFQY---LSFGAYGMVLKAKNVKDNREIVLKFQKCQN
Kinase 10617.AA TyrKc 311-543 15 0.000316 -154.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 311-543
Range on HMM: 1-280/280
Sequence Identity: 15% (48 aa)

YQTKKIIAVSGEGVIFDGIQNQEITKQQKEVVIKVQFNEVDIDLLKLLDIQQSFTQ-----YEY-----NIVNLLDFVVQQ-------NFQILVLEKCEM
 . .|..     |... |. .        .| .|.  ..           .. | .      ..     |||.|.  ..||           .|.| .. 
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH

-DLSQKLKNIKNDTFEELKLLNMIFDLLDGL--ITFQLYYIIHCDIKPSNILVNQQERYFYTDFGISLIALPN--------QNQIQY--SYT--APFA--
 || . |.. ... .   .||.. ..  .|   .  .   .|| |.   |.||. . .   .||| |                  .   .     |    
GDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

SPEQLNKQCICYKTDVYS----------------LG-----KTFNTIFDKVNEQ--LPKYIA--------DFKILINTYML---DNEPSKRKNCLELHEM
.|| .|. .   |.||.|                 |     ..   .. .| .   .|.             . . .  |.   . .|..| .  |.|| 
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHEC

F
|
F
Kinase 10617.AA Ciliate-B2 129-172 25 0.005527 2.74 In-house 1-48 (197) Show / Hide 
Range on Protein: 129-172
Range on HMM: 1-48/197
Sequence Identity: 25% (12 aa)

YEIQDLISKGEIGFVF---KAKNLKTQEEVAIKIINY-QQFNYCDIDD
| . . | ||  ||..   | . ..  ...|.||    |. .  .|..
YYLCKYINKGGCGFICEGYKKHSIREYQDLAFKIYFNKQDCDKEEIQH
TPR 10617.AA TPR 675-708 29 0.002275 18.44 SMART 1-34 (34) Show / Hide 
Range on Protein: 675-708
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

YTTYNNFGFILYNRQDYHQAIENLRKSIEIQTII
. ...| | ..|.. || .||| ..|..|..   
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 10617.AA TPR_1 675-705 29 0.007856 13.87 Pfam 1-31 (34) Show / Hide 
Range on Protein: 675-705
Range on HMM: 1-31/34
Sequence Identity: 29% (9 aa)

YTTYNNFGFILYNRQDYHQAIENLRKSIEIQ
. ...| | ..|....| .||| ..| .|..
AEAWYNLGNCYYKMGNYDEAIECYQKALELN
TPR_1 10617.AA TPR_1 718-743 38 0.000885 17.18 Pfam 1-26 (34) Show / Hide 
Range on Protein: 718-743
Range on HMM: 1-26/34
Sequence Identity: 38% (10 aa)

AITQLNIAFCYTKLKEYQIAIEYCSK
| .  |.. || |...|. |||.. |
AEAWYNLGNCYYKMGNYDEAIECYQK
TPR 10617.AA TPR 718-751 29 0.048062 12.17 SMART 1-34 (34) Show / Hide 
Range on Protein: 718-751
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

AITQLNIAFCYTKLKEYQIAIEYCSKSYSDFQKI
| . .|.. || |...|. |||...|. .   . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 10617.AA TPR 760-793 23 0.045489 12.38 SMART 1-34 (34) Show / Hide 
Range on Protein: 760-793
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

FHFENLIGTCYYNLEDYSKAKQKLKISQEIAEQF
    . .| |||...|| .| . .. . |.....
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 10617.AA TPR_1 764-793 23 0.48505 7.62 Pfam 5-34 (34) Show / Hide 
Range on Protein: 764-793
Range on HMM: 5-34/34
Sequence Identity: 23% (7 aa)

NLIGTCYYNLEDYSKAKQKLKISQEIAEQF
. .| |||....| .| . ..   |. ...
YNLGNCYYKMGNYDEAIECYQKALELNPNN