Gene 18715 (Tetrahymena)

18715

Species: Tetrahymena
Alias: TTHERM_00469130, 18715, 1104, PreTt18715, 3710.m00118, 55.m00270
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E6

Sequence

Name Sequence Type Origin Length Description Download
18715.AA Protein None 2120 None Fasta, JSON
18715.kin_dom Protein Kinase Domain None 73 None Fasta, JSON
18715.NA RNA None 6363 None Fasta, JSON

Protein domain

Protein domains of 18715.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TPR 18715.AA TPR 197-230 41 1.3e-08 35.85 SMART 1-34 (34) Show / Hide 
Range on Protein: 197-230
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

SNALLDQANFYNKQKEFDKAIEYYDQAMEVDTNN
. |.. ..| | |....|.|||.|..|.|.| ||
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 18715.AA TPR_1 197-230 38 1.9e-07 29.96 Pfam 1-34 (34) Show / Hide 
Range on Protein: 197-230
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

SNALLDQANFYNKQKEFDKAIEYYDQAMEVDTNN
..|.   .| | |....|.|||.|..| |.. ||
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 18715.AA TPR_1 231-264 35 6e-06 24.67 Pfam 1-34 (34) Show / Hide 
Range on Protein: 231-264
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

INILVGKGDCLRKQGQYEAALECYEYGMNLNPPH
 ...  .| |..|.|.|..|.|||.    ||| .
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 18715.AA TPR_2 231-264 35 7e-06 24.86 Pfam 1-34 (34) Show / Hide 
Range on Protein: 231-264
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

INILVGKGDCLRKQGQYEAALECYEYGMNLNPPH
  ..   |.|..|||.|. |.|.||    |.| .
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 18715.AA TPR 231-264 32 8e-06 26.55 SMART 1-34 (34) Show / Hide 
Range on Protein: 231-264
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

INILVGKGDCLRKQGQYEAALECYEYGMNLNPPH
. ..  .| |..|.|.|. |.|||.  . |.| .
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 18715.AA TPR_2 197-230 41 0.000106 20.72 Pfam 1-34 (34) Show / Hide 
Range on Protein: 197-230
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

SNALLDQANFYNKQKEFDKAIEYYDQAMEVDTNN
  |.  ... | ||...|.|||||..| . | ||
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 18715.AA TPR 268-301 52 8.5e-10 39.79 SMART 1-34 (34) Show / Hide 
Range on Protein: 268-301
Range on HMM: 1-34/34
Sequence Identity: 52% (18 aa)

FRILFNKGNIYKCMGKNKEAIECYSKASLLDPQN
 ....|.||.|  ||. .||||||.||  |||.|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 18715.AA TPR_1 268-301 50 2.2e-09 36.76 Pfam 1-34 (34) Show / Hide 
Range on Protein: 268-301
Range on HMM: 1-34/34
Sequence Identity: 50% (17 aa)

FRILFNKGNIYKCMGKNKEAIECYSKASLLDPQN
 ....|.||.|  ||. .|||||| ||  |.|.|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 18715.AA TPR 370-403 29 1.5e-07 32.34 SMART 1-34 (34) Show / Hide 
Range on Protein: 370-403
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

ARQYLNKGNALFQIDKLEDALICYKKAIMIENNF
|. ..|.||....  ....|. ||.||. .. |.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 18715.AA TPR_1 370-403 29 1.6e-07 30.24 Pfam 1-34 (34) Show / Hide 
Range on Protein: 370-403
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

ARQYLNKGNALFQIDKLEDALICYKKAIMIENNF
|. . |.||....  ....|. ||.||. .. |.
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 18715.AA TPR_1 302-335 26 1.7e-07 30.11 Pfam 1-34 (34) Show / Hide 
Range on Protein: 302-335
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

PNTYFNKALAFYSLGELDEVIDNYSRVVKQNPRD
.....|.....|..|..|| |. | .... || .
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 18715.AA TPR_2 268-301 44 2.2e-07 30.18 Pfam 1-34 (34) Show / Hide 
Range on Protein: 268-301
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

FRILFNKGNIYKCMGKNKEAIECYSKASLLDPQN
.....| |..|  .|. .||||.| ||  |||.|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 18715.AA TPR 472-505 32 3.1e-07 31.3 SMART 1-34 (34) Show / Hide 
Range on Protein: 472-505
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

VNAYINKGLSQYILGQFKESYDSYKEALKIDNNS
. |. |.|.. | .|...|  . |..||..| | 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 18715.AA TPR_1 472-505 29 4.9e-07 28.54 Pfam 1-34 (34) Show / Hide 
Range on Protein: 472-505
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

VNAYINKGLSQYILGQFKESYDSYKEALKIDNNS
..|. |.|. .| .|...|  . |..||... | 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 18715.AA TPR_1 438-471 23 5.1e-07 28.49 Pfam 1-34 (34) Show / Hide 
Range on Protein: 438-471
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

VKALYNQAVALRELGEVEESAKQFDKVIKINPKM
..|.|| .......|. .|  . ..|....||. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 18715.AA TPR 404-437 44 5.4e-07 30.47 SMART 1-34 (34) Show / Hide 
Range on Protein: 404-437
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

YEAFLNMGVVLNELGRTVEEIECYKKVLELKPDD
.||..|.|...  .|.  | ||||.|.||| |..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 18715.AA TPR 302-335 23 2e-06 28.39 SMART 1-34 (34) Show / Hide 
Range on Protein: 302-335
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

PNTYFNKALAFYSLGELDEVIDNYSRVVKQNPRD
. ...|.....|..|..|| |. |..... .| .
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 18715.AA TPR 438-471 20 2e-06 28.89 SMART 1-34 (34) Show / Hide 
Range on Protein: 438-471
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

VKALYNQAVALRELGEVEESAKQFDKVIKINPKM
..|.||...... .|. .|  . ..|.....|. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 18715.AA TPR_2 438-471 23 2e-06 27.0 Pfam 1-34 (34) Show / Hide 
Range on Protein: 438-471
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

VKALYNQAVALRELGEVEESAKQFDKVIKINPKM
..|.||........|. .| .. ..|..|..|. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 18715.AA TPR_1 404-437 44 3e-06 25.99 Pfam 1-34 (34) Show / Hide 
Range on Protein: 404-437
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

YEAFLNMGVVLNELGRTVEEIECYKKVLELKPDD
.||. |.|... ..|.  | ||||.|.||| |..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 18715.AA TPR_1 506-539 32 9e-06 24.17 Pfam 1-34 (34) Show / Hide 
Range on Protein: 506-539
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

IESYINMSQCLRQMKKSNKALKLLMKALKISPNN
 | . |. .|...|.. ..|.. . |||.. |||
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 18715.AA TPR_2 472-505 35 1e-05 24.29 Pfam 1-34 (34) Show / Hide 
Range on Protein: 472-505
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

VNAYINKGLSQYILGQFKESYDSYKEALKIDNNS
. |. | |.. | .|...|  . |..|||.| | 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 18715.AA TPR 506-539 32 1.1e-05 26.13 SMART 1-34 (34) Show / Hide 
Range on Protein: 506-539
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

IESYINMSQCLRQMKKSNKALKLLMKALKISPNN
.| . |. .|...|.. ..|.. . |||.. |||
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 18715.AA TPR_2 506-539 35 1.4e-05 23.78 Pfam 1-34 (34) Show / Hide 
Range on Protein: 506-539
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

IESYINMSQCLRQMKKSNKALKLLMKALKISPNN
 | . |. ||......  .|.... ||||. |||
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 18715.AA TPR_2 370-403 23 2.8e-05 22.75 Pfam 1-34 (34) Show / Hide 
Range on Protein: 370-403
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

ARQYLNKGNALFQIDKLEDALICYKKAIMIENNF
|. . | |.....  ....|. .|.||. .. |.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 18715.AA TPR_1 540-573 29 3.4e-05 22.1 Pfam 1-34 (34) Show / Hide 
Range on Protein: 540-573
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

FELYFQIGEIYKQILNIKKALEYYSYSIQLNPIY
 | ....| .| .  | ..|.|.|   ..||| .
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 18715.AA TPR 540-573 23 0.0001 22.95 SMART 1-34 (34) Show / Hide 
Range on Protein: 540-573
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

FELYFQIGEIYKQILNIKKALEYYSYSIQLNPIY
 | ....|..| .  ....|.|.|. ...|.| .
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 18715.AA TPR_2 302-335 26 0.000171 19.99 Pfam 1-34 (34) Show / Hide 
Range on Protein: 302-335
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

PNTYFNKALAFYSLGELDEVIDNYSRVVKQNPRD
.  ..| ... | .|..|| |. | ...| .|..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 18715.AA TPR_2 540-573 26 0.000483 18.39 Pfam 1-34 (34) Show / Hide 
Range on Protein: 540-573
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

FELYFQIGEIYKQILNIKKALEYYSYSIQLNPIY
.|.....|..| .  . ..|.|||  ...|.| .
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 18715.AA TPR_1 608-641 23 0.00135 16.54 Pfam 1-34 (34) Show / Hide 
Range on Protein: 608-641
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

PKPHINKGQIYEVQGKLKSALRQYDMAVTLKNGQ
.. . |.|..|. .|... |.  |. |. |    
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 18715.AA TPR 608-641 23 0.002542 18.28 SMART 1-34 (34) Show / Hide 
Range on Protein: 608-641
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

PKPHINKGQIYEVQGKLKSALRQYDMAVTLKNGQ
.. . |.|..|. .|... |.  |. |..|    
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 18715.AA TPR_1 574-607 26 0.003828 14.96 Pfam 1-34 (34) Show / Hide 
Range on Protein: 574-607
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

SEAIFQKGVCLSIINELESANKCFDLCIKFNPSN
.|| ...|.|.   .... | .|.. ... ||.|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 18715.AA TPR_2 608-641 29 0.00696 14.29 Pfam 1-34 (34) Show / Hide 
Range on Protein: 608-641
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

PKPHINKGQIYEVQGKLKSALRQYDMAVTLKNGQ
.. . | ||.|. ||... |.. |. |. |  . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 18715.AA TPR_1 338-369 34 0.014225 12.97 Pfam 3-34 (34) Show / Hide 
Range on Protein: 338-369
Range on HMM: 3-34/34
Sequence Identity: 34% (11 aa)

ALLNKGMALREIGEFGPAVECFVKASEMKARN
|. |.|..... |..  |.||. || |.   |
AWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 18715.AA TPR_2 574-607 23 0.017086 12.91 Pfam 1-34 (34) Show / Hide 
Range on Protein: 574-607
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

SEAIFQKGVCLSIINELESANKCFDLCIKFNPSN
 || .. |.|.   .... | .... ..| .| |
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 18715.AA TPR 574-607 23 0.022716 15.03 SMART 1-34 (34) Show / Hide 
Range on Protein: 574-607
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

SEAIFQKGVCLSIINELESANKCFDLCIKFNPSN
.|| ...|.|.   .... | .|.. ... .|.|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 18715.AA TPR_2 404-437 38 0.043048 11.49 Pfam 1-34 (34) Show / Hide 
Range on Protein: 404-437
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

YEAFLNMGVVLNELGRTVEEIECYKKVLELKPDD
 ||  |.|... ..|.  | ||.|.|.|.| |..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 18715.AA TPR 336-369 32 0.070647 10.7 SMART 1-34 (34) Show / Hide 
Range on Protein: 336-369
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

QHALLNKGMALREIGEFGPAVECFVKASEMKARN
  |..|.|....  |..  |.||. || |.   |
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 18715.AA TPR_2 336-369 26 0.163423 9.44 Pfam 1-34 (34) Show / Hide 
Range on Protein: 336-369
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

QHALLNKGMALREIGEFGPAVECFVKASEMKARN
  |. | |..... |..  |.|.. || .   .|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 18715.AA TPR 839-872 17 0.19578 6.81 SMART 1-34 (34) Show / Hide 
Range on Protein: 839-872
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

VLSYIYIGLKKRERKEFDESILYFEFLMNLDKDL
.  .  .|.  . ....|| | ...  . || . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 18715.AA TPR_2 839-872 23 8.429603 3.38 Pfam 1-34 (34) Show / Hide 
Range on Protein: 839-872
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

VLSYIYIGLKKRERKEFDESILYFEFLMNLDKDL
.  . ..|.  ......|| | |.| .  || . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 18715.AA TPR_1 839-872 14 16.969811 2.23 Pfam 1-34 (34) Show / Hide 
Range on Protein: 839-872
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

VLSYIYIGLKKRERKEFDESILYFEFLMNLDKDL
.  .  .|.  ......|| | ...    |. . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
Kinase 18715.AA Ciliate-E6 986-1063 30 2.7e-34 106.64 In-house 1-84 (154) Show / Hide 
Range on Protein: 986-1063
Range on HMM: 1-84/154
Sequence Identity: 30% (26 aa)

IQNILNHRNIQKINYMY-FDHEENIYFIEPRQKYNLEAHLH--QYIVSFEQR---LNILLQISQAVQYLHSNGIVHGNISMKNI
|||..|........||. |..|........|...||....|  .......|.   .....|...||.||||...|..||. |||
IQNLKNCNHPNILKYMDSFQIENYYFIVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKNYVLQNITLKNI
Kinase 18715.AA TKL 1024-1067 30 4.5e-10 32.49 In-house 126-175 (364) Show / Hide 
Range on Protein: 1024-1067
Range on HMM: 126-175/364
Sequence Identity: 30% (16 aa)

LHQYIVSFEQRLNILLQISQAVQYLHSNG--------IVHGNISMKNILIRN
||...  ..||... |.|.....||||..        |.| ..  ||||. .
LHYLH--WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDE
Kinase 18715.AA Ciliate-C3 1033-1076 47 1.2e-09 30.93 In-house 97-140 (140) Show / Hide 
Range on Protein: 1033-1076
Range on HMM: 97-140/140
Sequence Identity: 47% (21 aa)

QRLNILLQISQAVQYLHSNGIVHGNISMKNILIRNSDFIPLLTG
|.| |  || ||..|||   |||| | ..||||   | | ..  
QKLQISKQILQAIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF
Kinase 18715.AA Ciliate-E2 930-1083 21 9.5e-09 26.14 In-house 32-206 (365) Show / Hide 
Range on Protein: 930-1083
Range on HMM: 32-206/365
Sequence Identity: 21% (41 aa)

EDTTKQQTQQ----QQQQQQIKLSNISKQLLENFEK-ELVCRKIKSTVFKTNKDQYYKQFA---IQNILNHRNIQKINYMYFD-HEENIYFIEPRQKYNL
.| .||  .|    ....... . ...|. .|.... . ..|.|..         | |.     |. .||| || |. . . .  ..|||..     |  
ID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-F-------Y-KKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLV---MEYCQ

EAHLHQYIVSF----------------EQRLNILLQISQ---------------AVQYLHSNG-IVHGNISMKNILIRNSDFIPLLTGFRNSRII
   | .|| ..                .....|  || |               |..||||.. |.| .|   |||.      . .. | .|...
GGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------IKIIDFGLSKKY
Kinase 18715.AA TK-Unique 1035-1065 30 1.1e-08 26.16 In-house 134-166 (294) Show / Hide 
Range on Protein: 1035-1065
Range on HMM: 134-166/294
Sequence Identity: 30% (10 aa)

LNILLQISQAVQYLHS--NGIVHGNISMKNILI
.... || .. .||.|   .|||......|.|.
YHFAWQIACGMEYLASQRKKIVHRDLCARNVLL
S_TKc 18715.AA S_TKc 898-1192 13 2.2e-08 -53.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 898-1192
Range on HMM: 1-231/231
Sequence Identity: 13% (44 aa)

FPLSEMIAKGSTSETYGISFDKNQINEHELSEEDTTKQQTQQQQQQQQIKLSNISKQLLENFEKELVCRKIKSTVFKTNKDQYYKQFAIQNILNHRNIQK
. . . | ||. .. |     |                                         ..  . .||        .. ..  .|    .| || |
YEILRKIGKGAFGKVYKCRHKK---------------------------------------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVK

INYMYFDHEENIYFIEPRQKY---NLEAHLHQYI-------VSFEQRLNILLQISQAVQYLHSNGIVHGNISMKNILIRNSDFIPLLTGFRNSRIILSTY
. ... |  ...|..         .|  .....         .  .   .. || .|..|.||.||.|  .   |||. .      .. |  .|..    
LYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL----

HSSSFQNIQQSNTKQPTLFFSANHNPNNFTSPDLTISLAE---DIYALGQVFEKMLL-----KIDQQDRMINNWYKKGFTSSLSLQKLVRNMLEHNKVYK
                |.  .      .. .| .  .      |....| ..  ||         |...|...        | ..  ..|..|. .   |
---------------TTFCGTP-----WYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------SPEAKDFIRKCLQKD-PEK

RPDITRVVE-------TLQF
|| .  . .          |
RPTA-EALQDEWDIKCHPWF
Kinase 18715.AA Jak 1040-1067 32 6.6e-08 24.1 In-house 126-153 (299) Show / Hide 
Range on Protein: 1040-1067
Range on HMM: 126-153/299
Sequence Identity: 32% (9 aa)

QISQAVQYLHSNGIVHGNISMKNILIRN
|| ....||......||.....|||. .
QICWGMHYLEDKRYIHGDVCARNILVDR
Kinase 18715.AA TBCK 1035-1065 35 1.2e-07 23.35 In-house 83-113 (346) Show / Hide 
Range on Protein: 1035-1065
Range on HMM: 83-113/346
Sequence Identity: 35% (11 aa)

LNILLQISQAVQYLHSNGIVHGNISMKNILI
|.|  ||... .|.|. .|||.. . .||..
LCIYYQILCGLSYMHKHHIVHRFLHPHNIYL
Kinase 18715.AA CAMK-Unique 1035-1068 35 1.4e-07 20.91 In-house 160-193 (363) Show / Hide 
Range on Protein: 1035-1068
Range on HMM: 160-193/363
Sequence Identity: 35% (12 aa)

LNILLQISQAVQYLHSNGIVHGNISMKNILIRNS
..| ... .|| |.||..|||...   ||....|
CFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYS
Kinase 18715.AA Ciliate-E8 985-1069 32 1.8e-07 19.43 In-house 37-126 (138) Show / Hide 
Range on Protein: 985-1069
Range on HMM: 37-126/138
Sequence Identity: 32% (29 aa)

AIQNILNHRNIQKINYMYFDHEENIYFIEPRQKYNLEAHLH-QYIV----SFEQRLNILLQISQAVQYLHSNGIVHGNISMKNILIRNSD
.||  . |||||.|  .|      |  .  .|  ||   |    |       ..|.   .||  | .|||.| |.|  .   |||..  |
CIQMLVCHRNIQNIYDVYQNENNKIVIVQKMQGENLRKYLKFKKIDGSYICQNKRMGYIQQIMDAFCYLHNNNIIHCDFKLNNILVQRND
Kinase 18715.AA Gdt 1030-1065 41 1.8e-07 21.65 In-house 128-163 (289) Show / Hide 
Range on Protein: 1030-1065
Range on HMM: 128-163/289
Sequence Identity: 41% (15 aa)

SFEQRLNILLQISQAVQYLHSNGIVHGNISMKNILI
|. | . |.. |. . |.||.|||.|...   ||||
SMIQKIRIMIDIAKGCQFLHQNGIIHRDLKPDNILI
Kinase 18715.AA Pkinase 1022-1055 27 4e-05 19.19 Pfam 89-131 (293) Show / Hide 
Range on Protein: 1022-1055
Range on HMM: 89-131/293
Sequence Identity: 27% (12 aa)

AHLHQYIV---------SFEQRLNILLQISQAVQYLHSNGIVH
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MDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIH