Gene 2103 (Tetrahymena)

2103

Species: Tetrahymena
Alias: PreTt02103, 3798.m00216, TTHERM_01080610, 2103, 268, 222.m00059
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
2103.AA Protein None 656 None Fasta, JSON
2103.kin_dom Protein Kinase Domain None 257 None Fasta, JSON
2103.NA RNA None 1971 None Fasta, JSON

Protein domain

Protein domains of 2103.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 2103.AA ULK 104-360 34 9.5e-119 400.8 In-house 1-329 (329) Show / Hide 
Range on Protein: 104-360
Range on HMM: 1-329/329
Sequence Identity: 34% (114 aa)

YIMANEIGKGSFAKVFKGINSET----GEKVAIKKIDKNKFDKQYLE--------LIDSEISVLSQLN--------NEHIIKFLDLFNEG--DYIYIVTE
|.. ...|||||.||.||.| .|    .||||.|.|||.|..... |        |...|| .. .|.        ...|.|..| |..   ..|||..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCELGDLEVFIKNNFSA-----TKLRLPEELVKVFAYQILLAFLGIADMNIIHRDMKLANVLITKDF------------HLKVADFGLAKSSFEK-----
.|. |||| .||.|        .| ||.|. .. | .||| .|  . ..||||||.|..|.||....            .||.||||.||.  .      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-DKDQV------GTPMTMAPEVLNNLG----YD-SRCDVWSVGCMIYEMLEGRAP----FLPTNNGGIEELKRL-------INQRQLIFR-----QNISQ
  . .|      |||..|||..|...|    |. . ||.||.||..|||| |. |    | .... .|..|...       |....| |.     ..||.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

SAQNLIDQMLTLNPKKRISWHEMFNHEWF
  ..|| .||. ..|.||||.|.|||.||
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 2103.AA ULK 104-360 34 7e-118 397.93 In-house 1-324 (324) Show / Hide 
Range on Protein: 104-360
Range on HMM: 1-324/324
Sequence Identity: 34% (111 aa)

YIMANEIGKGSFA-KVFKGINSET---GEKVAIKKIDKNKFDKQYLE--------LIDSEISVLSQLN---NEH--IIKFLDLFNEG--DYIYIVTELCE
|.. ...|||||. ||.||.| .|   ...||.|.|||.|. |...|        |...||... .|.   ...  |.|..| |..   ..|||..|.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

LGDLEVFIKNNFSA----TKLRLPEELVKVFAYQILLAFLGIADMNIIHRDMKLANVLITKDF------------HLKVADFGLAKSSFE------KDKD
 |||| .||.|       .| ||.|. .. | .||. .|  . ..||||||.|..| ||....            .||.||||.||. ..      . . 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

QV------GTPMTMAPEVLNNLG----YD-SRCDVWSVGCMIYEMLEGRAP----FLPTNNGGIEEL-------KRLINQRQLIFR-----QNISQSAQN
.|      |||..|||..|...|    |. . ||.||.||..|||| |. |    | ..... |..|       . .|..... |.     ..||.  ..
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIDQMLTLNPKKRISWHEMFNHEWF
|| .||. ..|.||||.|.|||.||
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 2103.AA S_TKc 104-360 33 1.4e-91 311.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 104-360
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

YIMANEIGKGSFAKVFKGINSETGEKVAIKKIDKNKFDKQYLELIDSEISVLSQLNNEHIIKFLDLFNEGDYIYIVTELCEL--GDLEVFIKNNFSATK-
| . ..||||.|.||.|... .||..||||.|.         | | .||..|.. . ..|.|..| | . |..|.|.|.|.   |||  .||.. .  . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

LRLPEELVKVFAYQILLAFLGIADMNIIHRDMKLANVLITKDFHLKVADFGLAKSSFEKDKDQVGTPMTMAPEVLNNLGYDS-RCDVWSVGCMIYEMLEG
 ..||  .. ..|||..|   . ...||||| | .|.|...  |.|..|||||.      . ..|||  ||||||   ||.  .||.||.||..|||| |
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

RAPFLPTNNGGIEELKRLINQRQLIFRQNISQSAQNLIDQMLTLNPKKRISWHEMFN-------HEWF
. ||         ........         |..| ..|...|. .|.||..  | ..       |.||
YPPFP--------QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 2103.AA AGC 104-360 22 2.8e-81 209.1 In-house 1-395 (395) Show / Hide 
Range on Protein: 104-360
Range on HMM: 1-395/395
Sequence Identity: 22% (91 aa)

YIMANEIGKGSFAKVFKGINS------ETGEKVAIKKIDKNK---FDKQ-YLELIDSE------------ISVLSQLN----------NEHIIK-FLDLF
. .   |||||| ||.            ||.  |.|...| .    .|.  .| . .|              .|...|          .  |.|     |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

NEGDY--IYIVTELCE--------LGDLEVFIKNN-FSATKL---RLPEELVKVFAYQ-------ILLAFLGIAD-MNIIHRD-MKLANVLITKDFHLKV
   |.  .|.| |...         |..| |. .       .   |..|| .. .| .       |.||.  . . |.||||| .|. |.|...| |.| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGR----RKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKL

ADFGLAKSSF-----------------------------------------------------EKDKDQVG--TPMTMAPEVLNNLGYDSRCDVWS--VG
.||||.|                                                        .. .  .|  ||  ||||.|    |.  || ||  .|
TDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLG

CMIYEMLEGRAPFLPTNNG-------GIEELKRLIN------QRQLIFR----------QNISQSAQNLIDQMLTLNPKKRIS----------WHEMFNH
|..|||| |. ||   |..         .|.  .|       . .. |           ...|. |..|| ..|. .|.||.             |  ||
CLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNH

EWF
.||
PWF
Kinase 2103.AA Ciliate-E2 104-360 25 2.4e-76 259.92 In-house 1-365 (365) Show / Hide 
Range on Protein: 104-360
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

YIMANEIGKGSFAKVFKGINSETGE------------------KVAIKKIDKNKFDKQYLELIDSEISVL----------------SQLNNEHIIKFLDL
|.  . ||.|.|..|.|. . ....                  ||.||.. .. . |. .| | .||...                .|||. .|||. . 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FN--EGDYIYIVTELCELGDLEVFIKNN--FSATK----LRLPEELVKVFAYQILL---------------AFLGIADMN-IIHRDMKLANVLITKDFHL
|     ..||.|.|.|. |||. .||||  ..  .    ... |. .| . .|||                |.  .   | ||||| |. |.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KVADFGLAKSSFEKDKD----------------------------------QVGTPMTMAPEVLNNLG---------YDSRCDVWSVGCMIYEMLEGRAP
|..||||.|   .. ..                                  ..|||. ||||.||. .         ||  ||.||.|...|||| |. |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FLPTNNGGIEELKRLINQRQLIFR------------------QNISQSAQNLIDQ----MLTLNPKKRIS-WHEMFNHEWF
|            . | | .. |.                  ...||....|| .    ||  .|.|||. | . .||.||
F-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 2103.AA Pkinase 104-360 30 1.6e-75 262.03 Pfam 1-293 (293) Show / Hide 
Range on Protein: 104-360
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

YIMANEIGKGSFAKVFKGINSETGEKVAIKKIDKNKFDKQYLELIDS--EISVLSQLNNEHIIKFLDLFNEGDYIYIVTELCELG----DLEVFIKNNFS
|     ||.|||..|.|...  ||..||.|.|.| . ... ..      ||...  || ..|....| | ..|.||.|.|.|| |    ||  .|.    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

ATKLRL--PEELVKVFAYQILLAFLGIADMNIIHRDMKLANVLITKDFHL----KVADFGLA----KSSFEKDKDQVGTPMTMAPEVLN-NLGYDSRCDV
  . ..  .|. .| ..|||| .   . .|.|||||.|..|.|| .. |.    |..|||||      . .  .. .|||  |||||.. . .|....|.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSVGCMIYEMLEGRAPFLPT----NNGGIEELKRLINQRQLIFRQNIS---------------------QSAQNLIDQMLTLNPKKRISWHEMFNHEWF
||.||..|||| || ||       |     .. ..| ...| |    .                     .... .|. .|...||||..... ..|.||
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 2103.AA CAMK 109-360 21 2e-72 232.49 In-house 1-425 (425) Show / Hide 
Range on Protein: 109-360
Range on HMM: 1-425/425
Sequence Identity: 21% (90 aa)

EIGKGSFAKVFKGINSETG------------EKVAIKKIDKNKFD--------------------------KQYLELIDSEISVLSQ-------LNNEHI
..|.|||.||...|. .|.            .||||| |||.| .                           . .. . .||.....       |. ..|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKFLDLFNEGDY-------------------IYIVT---ELCELG----DLEVFIKNNFS----------ATKL-RLPEELVKVFAYQILLAFLGIADMN
||... .  ..|                   .|.|.   |.|. |    ||  .|. . .          . .  |..|. .. .  ||. |   . ..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDMKLANVLITKD-----------------FHLKVADFGLAKSSFE--------------------------KDKDQVGTPMTMA-PEVLNN-----
|.||| |. |.|....                 . .|..|||.|.  ..                          | |...|||  || |||||      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------LGYDSRCDVWSVGCMIYEMLEGRAPFLPTNNG----------GIEELKRLINQRQLIFRQN----------------ISQS--------AQ
          .|.  ||.||.|.. | || |. ||   ..            ..||.. | . .  |                   ||..        ..
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLIDQMLTLNPKKRISWHEMFNHEWF
.|| .||. .|.||.. ..  ||.|.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 2103.AA Ciliate-E2-Unclassified 104-360 24 2.1e-71 243.53 In-house 1-352 (352) Show / Hide 
Range on Protein: 104-360
Range on HMM: 1-352/352
Sequence Identity: 24% (87 aa)

YIMANEIGKGSFAKVFKGINSETGEKV-----AIKKIDKNKFDKQY-----LELIDSEIS--------------VLSQLNNEHIIKFLDLFNEGDYIYIV
|..   ||.|.|.||.| ...... ..     ..|......  ...     .|..  ..                |.......|.|... |.  ..||||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

TELCELGDLEVFIKNNFS------------ATKLRLPEELVK-----VFAYQILLAFLGIADMN-IIHRDMKLANVLITKD---FHLKVADFGLAKSS--
.|.|| |||. .||.. .             .. ...|. .|      ...|||...  .   | ||||| |. |.|....   ...|..|||..| .  
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----------------FEKDKDQVGTPMTM----APEVLNNLGYDSR----CDVWSVGCMIYEMLEGRAPFLPTNNGG-------------IEELKRLIN
                ... ....|||..|    ||||| . .|| .    ||.||.|. .|||| |. ||  .|                ...|.. |.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

QRQLIFR--------QNISQSAQNLID----QMLTLNPKKRISWHEMFNHEWF
|... |.        ...|..|...|     .||  ||.|||.. . .|| ||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 2103.AA STE 104-360 22 1.1e-68 234.52 In-house 1-359 (359) Show / Hide 
Range on Protein: 104-360
Range on HMM: 1-359/359
Sequence Identity: 22% (83 aa)

YIMANEIGKGSFAKVFKGINS------ETGEK---------VAIKKIDKNKFDK---------------QYLELIDSEISVLSQLN--NEHIIKFLDLFN
.    .||||.| .|.|..|       .|||.         .|||...... ..               . .. |  ||......|   ..|.|... . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EG-------DYIYIVTELCELGDLEVFIKNNFSATK---------LRLPEELVKVFAYQILLA-FLGIADMNIIHRDMKLANVLITKDFHLKVADFGLAK
 .       |...|. |... | |. .||....  |          |.||........||| .    . ...||||| | ||.|.      | .|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

SSFE-------------------KDKDQVGTPMTMAPEVLNN------LGYDSRCDVWSVGCMIYEMLEGRAPF---LPT-------NN-----------
.  .                   | .  ||||  |||||...       ||| .||.||.||.| ||..|. |.    |.       .|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---GGIEELKRLINQRQLIFRQ----------NISQSAQNLIDQMLTLNPKKRISWHEMFN--HEWF
   |..  |.  . | ..  ..          . |.. .. |.. |. .|.|| . ... .  |...
IVNGPPPPLPDHLSQNEM--ISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 2103.AA CAMKL 104-360 29 2.4e-60 191.22 In-house 1-297 (297) Show / Hide 
Range on Protein: 104-360
Range on HMM: 1-297/297
Sequence Identity: 29% (90 aa)

YIMANEIGKGSFAKVFKGIN-SETGEKVAIKKID--KNKFDKQYLEL-----------IDSEISVLSQLN---NEHIIKFLDLFNEGDY------IYIVT
|..  ..|||||.||  ... . |||||||| ||  | . | . .             |  ||. ...||    ..|||... .   ..      ||.|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCELGD--LEVFIKNNFSATKLRLPEELVKVFAYQILLAFLGIADMNIIHRDMKLANVLITKDF--HLKVADFGLA-------KSSFEKDKDQVGTPMT
|.|. |.  |  .|...      |.||.  . .  ||. |   . ...|.||| |. |.|....    .|..|||..       . . .| | . |.|  
EYCSGGEMDLFDYIVKHGHRR-GRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

MAPEVLNN--LGYD-SRCDVWSVGCMIYEMLEGRAPF-LPTNN----GGIEELKRLINQRQLIFR--QNISQSAQNLIDQMLTLNPKKRISWHEMFNHEW
||||...     ||    |.|| | . | |. |. ||  .|.|      | .|.. |..    ..    .| ....|| .||. ||.||.. |.  ||.|
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M
Kinase 2103.AA Ciliate-E2a 104-303 32 1.1e-54 159.45 In-house 1-216 (275) Show / Hide 
Range on Protein: 104-303
Range on HMM: 1-216/275
Sequence Identity: 32% (73 aa)

YIMANEIGKGSFAKVFKGINSETGEKVAIKKIDKNKFDKQY--LELIDSEISVLSQLNNEHIIKFLDLFNEGDYIYIVTELCELGDLE---VFIKNNFSA
|   ..||||.|..|..    .||.. |.||..| |.  |    | .  ||. ..||.. .|||. . .   ...|.|.|.|| |.|.   .  |..|. 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

TKLRLPEELVKVFAYQIL-LAFLGIADMNIIHRDMKLANVLIT---KD----FHLKVADFGLAKSS--FEK--DKDQVGTPMTMAPEVLNNLG------Y
      .. .. .  |.|  ... .   ||.||| |. |.|..   |.    . .|..|||||.     ||   . ..|||  .|||||||        |
------IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQY

DSRCDVWSVGCMIYEMLEGRAPF
|  ||.||.|...| .| |. ||
DTKCDMWSCGVIFYILLCGKPPF
Kinase 2103.AA CMGC 104-316 20 2.5e-51 166.4 In-house 1-365 (513) Show / Hide 
Range on Protein: 104-316
Range on HMM: 1-365/513
Sequence Identity: 20% (74 aa)

YIMANEIGKGSFAKVFKGIN--------------SETGEKVAIKKIDKNKFDKQYLE----------LIDSEISVLSQLN----------------NEH-
|   . ||.|....|.|...               ||.|.|||||| ... ..               .  ||. | .||                ... 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIKFLDLFNEGD-----------------YIYIVTELCELGDLEVFIKNNFS-----------------------ATKLRLPEELVKVFAYQILLA--FL
|.| .| |   .                 ..|.|.|...  ||  .||||                          ..  ..  ... ..|||| .    
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

GIADMN--IIHRDMKLANVLITKD--------------------FHLKVADFGLAKSSFEK-----------------DKDQVGTPMT--------MAPE
 .  ..  |||||.| .|.||...                    ..||..|||||..  .                  |. . . |.|         |||
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDD-KPNRPYTHYVVTRWYRAPE

VLNNLG----------YDSRCDVWSVGCMIYEMLEG-------RAPFLPTNNGG----------IEELKR
.| . .          |.. .|.|||||...||. |       . |. |....           |. |..
ILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFK
Kinase 2103.AA Pkinase_Tyr 104-303 25 3.4e-34 116.42 Pfam 1-216 (270) Show / Hide 
Range on Protein: 104-303
Range on HMM: 1-216/270
Sequence Identity: 25% (56 aa)

YIMANEIGKGSFAKVFKGINS----ETGEKVAIKKIDKNKFDKQY---LELIDSEISVLSQL-NNEHIIKFLDLFN-EGDY--IYIVTELCELGDLEVFI
 ..  ..|.|.| .|.||.      .|. .||.|.. |.. ...     ...  |.....|| ....|....     .|.   ||||.|....|||  . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KNN-FSATKLRLPEELVKVFAYQILLAFLGIADMNIIHRDMKLANVLITKDFHLKVADFGLAKSSFEKDKD-QVGTPMT-----MAPEVLNNLGYDSRCD
...  .  .| ... |.. ...||  .    ...|.||||    |.|.|.... |..|||||.  ...|   ....        ||||..|.  . .  |
RKHREDKQPLTMKD-LLQ-MCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

VWSVGCMIYEMLE-GRAP-F
||| |  ..|..  |. | .
VWSFGVLMWEIFTYGEQPTY
Kinase 2103.AA TyrKc 104-360 20 3.2e-25 91.01 SMART 1-280 (280) Show / Hide 
Range on Protein: 104-360
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

YIMANEIGKGSFAKVFKGINSETGEKVAIKKIDKNKFDKQYLELIDSEISVLSQL--NNEHIIKFLDLFNEG-------DYIYIVTELCELGDLEVFIKN
  .  ..| | | .|.||. .   ..||.|.. ...     .| . .|......|  ....|....    ..       . ..||.|....|||  ....
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NFSATKLRLPEELVKVFAYQILLAFLGIADMNIIHRDMKLANVLITKDFHLKVADFGLAKSSFEK-------DKDQV----GTP--MT---MAPEVLNNL
.       |. .    |..||      ....|.||||    |.|...... |..||||..   ..       |   .    |.   .    ||||..|  
HRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

GYDSRCDVWSVGCMIYEMLE-GRAPFLP-TN--NGGIEELKRLINQRQLIFRQN--------ISQSAQNLIDQMLTLNPKKRISWHEMFNHEWF
 . .  |||| | ...|..  |  |    .      .| .... . . .   .|         ..   ... |    .|..| .  |   || |
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 2103.AA Ciliate-E2a 327-360 38 1.7e-11 30.13 In-house 242-275 (275) Show / Hide 
Range on Protein: 327-360
Range on HMM: 242-275/275
Sequence Identity: 38% (13 aa)

QNISQSAQNLIDQMLTLNPKKRISWHEMFNHEWF
...|.....|. .||  .|||||.  .  || ||
EKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 2103.AA CMGC 325-360 30 1.1e-09 27.07 In-house 478-513 (513) Show / Hide 
Range on Protein: 325-360
Range on HMM: 478-513/513
Sequence Identity: 30% (11 aa)

FRQNISQSAQNLIDQMLTLNPKKRISWHEMFNHEWF
.| .... | .|...||...|.|||.  .  .|..|
KRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF