Gene 8961 (Tetrahymena)

8961

Species: Tetrahymena
Alias: 1209, 3721.m00041, TTHERM_00564230, 75.m00159, PreTt08961, 8961
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: WNK

Sequence

Name Sequence Type Origin Length Description Download
8961.AA Protein None 1788 None Fasta, JSON
8961.kin_dom Protein Kinase Domain None 258 None Fasta, JSON
8961.NA RNA None 5364 None Fasta, JSON

Protein domain

Protein domains of 8961.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 8961.AA WNK 28-285 53 4.2e-184 599.72 In-house 1-261 (261) Show / Hide 
Range on Protein: 28-285
Range on HMM: 1-261/261
Sequence Identity: 53% (139 aa)

IRFNEELGFGAYKTVYRAYDNDSGCEVAWNVIKLQRLPLNERKRISEEIQLLKNLHHPNIINFINAWINK--SKNEVIFITECVSGGSLKKHLKKIKKPR
..|.||.|.|..|||||..|.....||||.....|.|..|||.|..||...||.|.||||..|.. |      |  .. .||    | ||  ||  || .
MKFDEEVGRGSFKTVYRGLDTETWVEVAWCELQDQKLSKNERQRFKEEAEMLKKLQHPNIVRFYDYWESVLCGKKCIVLVTELMTSGTLKTYLKRFKKMK

LKIIKNWCRQILKGLVYLHEQKPYPIIHRDIKCENVFISTTNNEIRIGDLGLAVSLKNSSHTKSVIGTPEFMAPEIYEEKYGTPVDIYSFGMCVLEMATL
 |. . ||||||||| .||...| ||||||.||.|.||..|.....||||||||.|||||..|||||||||||||.|||.|...||.|.||||.|||||.
PKVLRSWCRQILKGLHFLHTRQPHPIIHRDLKCDNIFITGTTGSVKIGDLGLAVTLKNSSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATS

STPYKECTSAAQVYKKVSQGILPYQIDLIQNEGLKNLILKCLSHYK-DRPSAEELLNDKFL
..||.||..|||.|.||.|||.|.....|||...|..|.||..|.| .|||...|||..|.
EYPYSECQNAAQIYRKVTQGIKPNSFQKIQNPEVKEIIEKCIRHNKEERPSIQQLLNHDFF
Kinase 8961.AA S_TKc 28-285 26 1.6e-67 231.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 28-285
Range on HMM: 1-231/231
Sequence Identity: 26% (74 aa)

IRFNEELGFGAYKTVYRAYDNDSGCEVAWNVIKLQRLPLNERKRISEEIQLLKNLHHPNIINFINAWINKSKNEVIFITECVSG--GSLKKHLKKIKKP-
 .. ...| ||. .||.......| .||  .||         ..|  |||.||. |||||.... .. .   ... ...|...|  |.|....|| ... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

-----RLKIIKNWCRQILKGLVYLHEQKPYPIIHRDIKCENVFISTTNNEIRIGDLGLAVSLKNSSHTKSVIGTPEFMAPEIYEEKYGT-PVDIYSFGMC
         .. ...||...| |.|...   |||||.| ||.....   .| |.| |||  |      ....|||..||||.   .||. ..|..|.| .
LRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCI

VLEMATLSTPYKECTSAAQVYKKVSQGILPYQIDLIQNEGLKNLILKCLS-HYKDRPSAEELLN-------DKFL
. ||..  .|.      ....||.              . .|..| |||    ..||.| |.|.       . ..
LYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 8961.AA STE 28-285 23 7.6e-63 215.1 In-house 1-359 (359) Show / Hide 
Range on Protein: 28-285
Range on HMM: 1-359/359
Sequence Identity: 23% (86 aa)

IRFNEELGFGAYKTVYRAYDND---------------SGCEVAWNVIKLQRLP---------------LNERKRISEEIQLLKNLH--HPNIINFINAWI
 .. |..| ||. |||.|....               .|. .|  ...|..                  .|...| .||...|...  ||||.... . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NKS-----KNEVIFITECVSGGSLKKHLK---KIKKPR-----------LKIIKNWCRQILKG-LVYLHEQKPYPIIHRDIKCENVFISTTNNEIRIGDL
...     ..|.  . | ..|||| . .|   ...||             ..|.  ||||||| | |||...   |||||||. |...      . . | 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL------VKLCDF

GLAVSLKN-----------------SSHTKSVIGTPEFMAPEIYEE-------KYGTPVDIYSFGMCVLEMATLSTPY---KEC---TSAAQVYKKVS--
|.. .| .                 ........||| .||||. .        .|.| .||.|.| ...||||   |.   .       ... |....  
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQF

-------QGILPYQIDLIQN-----------------EGLKNLILKCL-SHYKDRPSAEELLN--DKFL
       ... | . .| ||                 . .|. | |||   ...||.|..||.   .|.
EQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 8961.AA Pkinase 28-285 25 2e-61 215.17 Pfam 1-293 (293) Show / Hide 
Range on Protein: 28-285
Range on HMM: 1-293/293
Sequence Identity: 25% (78 aa)

IRFNEELGFGAYKTVYRAYDNDSGCEVAWNVIKLQRLPLNERKRISE--EIQLLKNLHHPNIINFINAWINKSKNEVIFITECVSGG----SLKKHLK--
... . .| |.. .||.... ..|..||  .||...   .....     |||..|.|.||||. .. .. .  |... ...|.. ||    .|. ...  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

KIKKP--RLKIIKNWCRQILKGLVYLHEQKPYPIIHRDIKCENVFISTTNNEI----RIGDLGLAVS--LKNSSHTKSVIGTPEFMAPEI--YEEKYGTP
. ..     . .|....|||.|| |.|..    |||||.| ||..|.  |..|    .|.| |||    . |.| .... |||..||||.    ..||..
RHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

VDIYSFGMCVLEMATLSTPYKEC-----TSAAQVYKKVSQGILPYQIDLIQN-------------------EGLKNLILKCLSH-YKDRPSAEELLNDKF
||..|.|  . ||..  .|....      .  |..... ...|.....   .                   | .| .| .||    |.||.||..|....
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

L
.
F
Kinase 8961.AA STE11 34-285 28 2e-54 187.12 In-house 7-303 (303) Show / Hide 
Range on Protein: 34-285
Range on HMM: 7-303/303
Sequence Identity: 28% (86 aa)

LGFGAYKTVYRAYDNDSGCEVAWNVIKLQRLP---------LNE---RKRISEEIQLLKNLHHPNIINFINAWINK-SKNEVIFITECVSGGSLKKHLK-
.| ||. |||.... | | ..|   |..|.           ...    | | |||.|.|.|.|.||. .. . . . ....|  . | ..||||.  |. 
IGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSLSSMLRH

KIKK--PRLKIIKNWCRQILKGLVYLHEQKPYPIIHRDIKCENVFISTTNNEIRIGDLGLAVSLKNSS-----------HTKSVIGTPE--------FMA
|  .     . |..  .|||.|| |||...   ||||||| .|... ...| ....| | |..|...            | ||. |||         .||
KWGPMKFDEMVIRKYTKQILEGLQYLHSHG---IIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMA

PEIYE-EK---YGTPVDIYSFGMCVLEMATLSTPYKECTS--AAQVYKKVSQGILPYQ-IDLIQN-----EGLKNLILKCLSHYKD-RPSAEELLNDKFL
||..  |.   ||...|| |.| .|.||||   |. ....  .|. .| ...   ...  . ..      | ... ...|. | .  ||.| .||...|.
PEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase 8961.AA Ciliate-E2 28-285 19 1.5e-52 178.67 In-house 1-365 (365) Show / Hide 
Range on Protein: 28-285
Range on HMM: 1-365/365
Sequence Identity: 19% (76 aa)

IRFNEELGFGAYKTVYRAYDNDSGC------------------EVAWNVIKLQRLPLNERKRISEEIQLLKNLH----------------HPNIINFINA
. |.. .|.|.. .||.. .   ..                  .|. . . . ..  |. . |. ||.... ..                |||||... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

WINKSKNEVIFITECVSGGSLKKHLKKIKKPR-----------LKIIKNWCRQILK---------------GLVYLHEQKPYPIIHRDIKCENVFISTTN
...|..| . ...| ..||.|....|. || |           .| ||.  .|||.               .| |||....  ||||||| ||...    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPENILF----

NEIRIGDLGLAVSLKNS--------------------------------SHTKSVIGTPEFMAPEIYEEK----------YGTPVDIYSFGMCVLEMATL
  | | |.||.  ....                                  .....|||..|||||.. |          |.. .||.|.|..  || . 
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

STPYKECTSAAQVYKKVSQGILPYQIDLIQNEGLK-----------------NLILK----CLS-HYKDRPS-AEELLNDKFL
 .|.         ...  |. . ..    |.. ..                 .|| |    .|    . |.. .|..|| ...
KPPF---------QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 8961.AA CAMK 33-216 18 2.2e-44 140.5 In-house 1-321 (425) Show / Hide 
Range on Protein: 33-216
Range on HMM: 1-321/425
Sequence Identity: 18% (59 aa)

ELGFGAYKTVYRAYDNDSG------------CEVAWNVIKLQRLP--------------------------LNERKRISEEIQLLKN-------LHHPNI
.|| |.. .|.....  ..             .||  .|. ..|.                           . ||..  ||...|.       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

INFINAWINKS-----------------KNEVIFIT---ECVSGG----SLKKHLKKIKK-------------PRL--KIIKNWCRQILKGLVYLHEQKP
|... .. ...                 ........   | .|||     |  .... ..              |.  .  . . |||. .. |.|... 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

YPIIHRDIKCENVFISTTN----------------NEIRIGDLGLAVSLKNSS------------------------HTKSVIGTPEFMA-PEIYEEK--
  |.|||.|.||. ... |                | | | | |.|  .. ..                          | . ||||.|| ||. . |  
--IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

-------------YGTPVDIYSFG
             || ..|. | |
CNMQNATDEEKPYYGPKCDMWSCG
Kinase 8961.AA Ciliate-E2-Unclassified 28-285 19 3.6e-44 151.12 In-house 1-352 (352) Show / Hide 
Range on Protein: 28-285
Range on HMM: 1-352/352
Sequence Identity: 19% (71 aa)

IRFNEELGFGAYKTVYRAYDNDSGCEV--------AWNVI-KLQRLPLNERKRISEEIQ----------------LLKNLHHPNIINFINAWINKSKNEV
 .... .| |.. .||...... . ..        . ..  |...    | ... .|..                .|.|. ||.|....  .. ..|. .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMF--YCFQDKQNI

IFITECVSGGSLKKHLKKIKK-----------------PRLKIIK-----NWCRQILKGLVYLHEQKPYPIIHRDIKCENVFISTTNN--EIRIGDLGLA
....| . ||.|....|| ||                    . .|     ....|||.|| |||...   |||||||.||....  ..  .|.| |.|..
YIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN--NIIHRDIKPENILFDNNGKNYYIKIIDFGIS

VSLKN----------------SSHTKSVIGTPEFM----APEIYEE-KYGTP----VDIYSFGMCVLEMATLSTPYK--ECTS-------------AAQV
  ...                . ......|||..|    |||.... .|...    .||.|.|..  || .   |..   |..               |.
KKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQL

YKKVSQGILPYQ------IDLIQNEGLKNLIL----KCLSHYKD-RPSAEELLNDKFL
|..  |... ..      |. . ..  |..|     |.|    . |...|..||  ..
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 8961.AA NEK 32-285 27 1.1e-42 148.17 In-house 5-286 (286) Show / Hide 
Range on Protein: 32-285
Range on HMM: 5-286/286
Sequence Identity: 27% (79 aa)

EELGFGAYKTVYRAYDNDSGCE-----VAWNVIKLQRLPLNERKRIS-EEIQLLKNLHHPNIINFINAWINKSKNEVIFITECVS-GGSLKKHLKKIKKP
...| |.. .||.. .   | .     ..|  |.....   |..    .|...|| |.||||. .....| . .|  . . |    || | ...|.||| 
KKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQ

RL-------KIIKNWCRQILKGLVYLHEQKPY---PIIHRDIKCENVFISTTNNE---IRIGDLGLAVSLKNS-SHTKS-VIGTPEFMAPEIY-EEKYGT
.        ..| .|. |....| |.|..|      |.|||||. |.|..  ||.   ..|||.|..  |... .. .. ..||| .|.||.  ...|. 
KQKGKYFEEEQIWDWFIQMCLALKYMHDRK-GPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYNN

PVDIYSFGMCVLEMATLST--PYKECT--SAAQVYKKVSQGILPYQIDLIQN----EGLKNLILKCLS-HYKDRPSAEELLNDKFL
 .|| |.| .. ||.||.   |  | .  .  . |.|. .|  |.   . ..    . |.||| ..|    ..|||....|.. |.
KSDIWSLGCVLYEMCTLKPKHPF-EAWDMNMPSLYMKIMKG--PQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 8961.AA TKL 34-280 20 3.1e-42 146.64 In-house 1-361 (364) Show / Hide 
Range on Protein: 34-280
Range on HMM: 1-361/364
Sequence Identity: 20% (74 aa)

LGFGAYKTVYRA-YDN-------DSGCEVAWNVIKLQRLPLNER-------------------------KRISEEIQLLKNLHHPNIINFINAWINKSKN
.| |.. .||.. . .       |.| .||  ..| .   ....                         ... ||| ....|.||||. |. . .. ...
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

E-----------VIFITECVSGGS-LKKHLKKIKKPRLKIIKNWCRQILKGLVYLHEQKP-----YPIIHRDIKCENVFISTTNNE-------------I
.             ...| ..||| |  ..       .  . .|...| .|. ||| ..|      ||||||.| .|...   ..              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

RIGDLGLAVSLKNSS--------------------HTKSVIGTPEFMAPEIYE-----------------EKYGTPVDIYSFGMCVLEMATLSTPYKECT
 |.|.||. ....|.                    .| ...||| .||||. .                 ..| . .|.||||..  |..|  .||..  
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

SAAQV---------YKKVSQGILPYQIDLIQN-----------EGLKNLILKCLSH-YKDRPSAEELL
.  ..         .. .. |  |   .  ||           ...|.|. .| .|  ..|||..|.|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEIL
Kinase 8961.AA NRBP 33-286 34 4e-38 131.54 In-house 1-261 (261) Show / Hide 
Range on Protein: 33-286
Range on HMM: 1-261/261
Sequence Identity: 34% (92 aa)

ELGFGAYKTVYRAYDNDSGCEVAWNVIK---LQRLPLNERKRISEEIQLLKNLHHPNIINFINAWINKSKNE--VIFITECVSGGSLKKHLKKIKKPR--
       ...| | |.. | || || ..   .. . ..| | | .  . |  |.|.||. |   |.. ....  |||||| .| ||.|. |||.|| .  
QRDVPGIDCAYLAMDTEEGVEVVWNEVQFSERKNFKAQEEK-IRQVFDNLIQLDHQNIVKFHKYWTDTKEEKPRVIFITEYMSSGSMKQFLKKTKKNHKN

--LKIIKNWCRQILKGLVYLHEQKPYPIIHRDIKCENVFISTTNNEIRIGDLGLAVSLKNSSHTKSVIGTPEFMAPEIY--EEKYG-TPVDIYSFGMCVL
  .|  | || |||  | |||   | ||||  . |. .||   |  |.||        ..    .       |.|||    | . . | ||||||||| |
MNEKAWKRWCTQILSALSYLHSCDP-PIIHGNLTCDTIFI-QHNGLIKIGCVWPDAIHHHVRTCREEMRNMHFFAPEYGILEVTDLTTAVDIYSFGMCAL

EMATLSTPYKECTSAAQVYKKVSQGILPYQIDLIQNEGLKNLILKCL-SHYKDRPSAEELLNDKFLD
||| |      |. .   |  |.. ..   | .....  ...|.||| .. ..||||.|||  . | 
EMAVLEI-QSGCQNGESEY--VTEEAIQRAIHSLEDPMQRDFIRKCLQKDPARRPSARELLFHQILF
Kinase 8961.AA MEKK2 29-285 34 5.8e-38 132.43 In-house 2-262 (262) Show / Hide 
Range on Protein: 29-285
Range on HMM: 2-262/262
Sequence Identity: 34% (93 aa)

RFNEELGFGAYKTVYRAYDNDSGCEVAWNVIKLQRLPLNERKRIS---EEIQLLKNLHHPNIINFINAWINKS-KNEVIFITECVSGGSLKKHLKKIKKP
|    || ||.  ||  || | | |.|   .. .    . || ..    |||||||| |. |. .     ..  |   ||. | ..|||.| .||     
RRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFM-EYMPGGSVKDQLKAYGAL

RLKIIKNWCRQILKGLVYLHEQKPYPIIHRDIKCENVFI-STTNNEIRIGDLGLAVSLK--NSSHT--KSVIGTPEFMAPEIYE-EKYGTPVDIYSFGMC
  .. . . |||| |. |||..    |.|||||  |.   |. |  ...|| | .  |.   .. |  ||| ||| .|.||. . | ||   |..| |  
TETVTRKYTRQILEGMHYLHDHM---IVHRDIKGANILRDSSGN--VKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVINGEGYGRKADVWSIGCT

VLEMATLSTPYKECTSAAQVYKKVSQGILPYQIDLIQNEGLKNLILKCLSHYKD-RPSAEELLNDKFL
| || |   |. |    | ..|   |   |   . . ... .. . .|  . |  ||||||||  .| 
VVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPQHVSQHA-RDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase 8961.AA TyrKc 28-284 23 1.8e-24 88.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 28-284
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

IRFNEELGFGAYKTVYRAYDNDSGCEVAWNVIKLQRLPLNERKRISEEIQLLKNL--HHPNIINFINAWINKSK-----NEVIFITECVSGGSLKKHLKK
|.....|| ||. .||..  .    .||   .|  .     |. . .|......|  |||||.... . . ..        .  ..| ...|.||..|.|
ITLGKKLGEGAFGEVYKGTWK---IQVA---VKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

IKK-PRLKIIKNWCRQILKGLVYLHEQKPYPIIHRDIKCENVFISTTNNEIRIGDLGLAVSLKNS------SHTKSV---IGTPE-----FMAPEIYEEK
 ..   .|   ..| || .|  |||..   ..||||. . |. ..  .  ..|.| ||.  ...       . ....    |.        ||||   ..
HRPKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

-YGTPVDIYSFGMCVLEMATL-STPYKEC----TSAAQVYKKVSQGILPYQIDL-------IQNEGLKNLILKCLSH-YKDRPSAEELLNDKF
 . |  |..||| |  |. |.  .|| .      |...|...| ||  . | .        .  . . .....|  .  .|||. .|.  ..|
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 8961.AA Pkinase_Tyr 28-178 26 2.8e-17 59.14 Pfam 1-158 (270) Show / Hide 
Range on Protein: 28-178
Range on HMM: 1-158/270
Sequence Identity: 26% (44 aa)

IRFNEELGFGAYKTVYRAYDN----DSGCEVAWNVIKLQ--RLPLNE--RKRISEEIQLLKNL-HHPNIINFINAWINKSKN-EVIFITECVSGGSLKKH
|.|...|| ||. .||... .    . ...||   .|         .  |.   .|....|.| |||||.... . . ...  ... ..| . .|.|...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVA---VKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LKK----IKKPRLKIIKNWCRQILKGLVYLHEQKPYPIIHRDIKCENVFISTTNNEIRIGDLGLA
|.|     ... .| . ..|.|| ||. ||....   .||||. . |. .. .|  ..|.| |||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENN-VVKICDFGLA
Kinase 8961.AA CAMK 257-285 30 9e-06 13.76 In-house 396-425 (425) Show / Hide 
Range on Protein: 257-285
Range on HMM: 396-425/425
Sequence Identity: 30% (9 aa)

EGLKNLILKCLSH-YKDRPSAEELLNDKFL
.  |.|| |.|    ..|...|. ||....
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 8961.AA Pkinase_Tyr 197-245 35 0.00015 16.03 Pfam 181-232 (270) Show / Hide 
Range on Protein: 197-245
Range on HMM: 181-232/270
Sequence Identity: 35% (19 aa)

MAPE-IYEEKYGTPVDIYSFGMCVLEMATLS-TP-YKECTSAAQVYKKV-SQG
|||| | . |. |  |..||| .  |. |.  .| |... | ..||...  .|
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGM-SNEEVYEYIYEDG