Gene p70RSK (Sea Urchin)

p70RSK

Species: Sea Urchin
Alias: p70RSK, Spk025, SPU_011124
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: AGC
Family: RSK
Subfamily: RSKp70

Sequence

Name Sequence Type Origin Length Description Download
p70RSK.AA Protein None 487 None Fasta, JSON
p70RSK.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of p70RSK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase p70RSK.AA p70 72-333 71 2.9e-220 738.02 In-house 1-299 (299) Show / Hide 
Range on Protein: 72-333
Range on HMM: 1-299/299
Sequence Identity: 71% (214 aa)

FQLLKVLGKGGYGKVFQVRKTTGKDSGKIFAMKVLKKAKIVRNQKDTAHTK-------------------------AERNILEAVQHPFIVDLHYAFQTG
|.||||||||||||||||||.||.|.|||.|||||.||||||||||||||.                         |||||||.|.||||.||||||||.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

GKLYLILAYLGGGELFMHLEREGIFMEDTACFYLSEIVLALEHLHKLGIIYRDLKPENIMLNKQGHVVLTDFGLCKESLEEGSM----------THTFCG
|||||||.||.||||||||||.||.||||||||||||..||||||..|||||||||||.|||.|||||||||||||||...|..          ||||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TIEYMAPEIVSRSGHGKDVDWWSLGALMYDMLTGGPPFTAENRKKTIEKILKGK--LSLPPYLTHEARDLVRKLLKRHISARLGSGPEDATRIRKHPFF
|||||||||..|.||...|||||||.|||||||||||||.|||||||.||||||  |.||||||||.|||..||||||...|.|.|||||..|..||||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase p70RSK.AA AGC 72-333 37 5e-192 502.09 In-house 1-395 (395) Show / Hide 
Range on Protein: 72-333
Range on HMM: 1-395/395
Sequence Identity: 37% (148 aa)

FQLLKVLGKGGYGKVFQVRKTTGK---DSGKIFAMKVLKKAK-IVRNQK-DTAHTKAE------------RNILEAVQ----------HPFIVD-LHYAF
|..|||.|||..|||..||| .|.   |.||..|||||||.. ||...| . .||..|            ||||| ..          |||||  |||.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTGGK--LYLILAYLG---------GG-ELFMHLE---REGIFMEDTACFYLSE-------IVLALEHLHK-LGIIYRD-LKPENIMLNKQGHVVLTDFG
|.  .  ||... |.          || |||.||    .||.| |..|.||..|       ||||||.||. .|||.|| ||||||.|...||. |||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKESLEEG--------------------------------------------------SMTHTFCG--TIEYMAPEIVSRSGHGKDVDWWS--LGALMY
||||   .|                                                   .|.||||  | |||||||.    .|| .||||  ||.|||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

DMLTGGPPFTAEN----------RKKTIEKIL------KGKLSLP----------PYLTHEARDLVRKLLKRHISARLGSGPED-----ATRIRKHPFF
 |||| |||...|          .... .||.      . |. .|          .... ||.||..|||... . |||.|..|     |  |..||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase p70RSK.AA RSK 75-333 59 4.2e-179 601.31 In-house 1-278 (278) Show / Hide 
Range on Protein: 75-333
Range on HMM: 1-278/278
Sequence Identity: 59% (166 aa)

LKVLGKGGYGKVFQVRKTTGKDSGKIFAMKVLKKAKIVRNQKDTAHTKAERNILEAVQ-HPFIVDLHYAFQTGGKLYLILAYLGGGELFMHLEREGI---
|||||.|||||||..||.|..|.|.|.|||||||||||..||||.||..||||||..| |||||.|||||||.||||||. |. |||||.||..|..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FMEDTACFYLSEIVLALEHLHKLGIIYRDLKPENIMLNK---QGHVVLTDFGLCKE-SLEEGSMTHTFCGTIEYMAPEIVS----RSGHGKDVDWWSLGA
|.||.||||..|||||.||||..|||.||||||||...    .||..|||||.||. .......|.|||.||||||||..     ..||.| .||||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LMYDMLTGGPPFTA---ENRKKTIEKILKGK--LSLP--PYLTHEARDLVRKLLKRHISARLGSGPEDATRIRKHPFF
|||.|||| |||..   .|||.....|.|||  |..|  .||..||.||.||.|.|. . |||.||.|| .|..||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase p70RSK.AA SGK 72-333 46 2.4e-150 467.79 In-house 1-283 (283) Show / Hide 
Range on Protein: 72-333
Range on HMM: 1-283/283
Sequence Identity: 46% (132 aa)

FQLLKVLGKGGYGKVFQVRKTTG---------------KDSGKIFAMKVLKKAKIV------RNQKDTAHTKAER-NILEAVQHPFIVDLHYAFQTGGKL
|..|||.|||..|||.||..                  .  .|..|||||.|. |.       . |   |..||| .||  . ||||| |||||||  ||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLILAYLGGGELFMHLEREGIFMEDTACFYLSEIVLALEHLHKLGIIYRDLKPENIMLNKQGHVVLTDFGLCKESLEEGSMTHTFCGTIEYMAPEIVSRS
|. . |. |||.| || ||..| || | || .|||.|||.||.. |||||||||||.|  |||..|||||||||  ..   | ||||| ||.|||.    
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GHGKDVDWWSLGALMYDMLTGGPPFTAENRKKTIEKILKGKLSLPPYLTHEARDLVRKLLKRHISARLGSGPEDATRIRKHPFF
.|.. ||||.||...|.|..| |||   |..   ..|....| .||. . .|.||   ||..  . |||.  .|.  |..||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase p70RSK.AA Akt 72-333 52 1.7e-145 468.08 In-house 1-264 (264) Show / Hide 
Range on Protein: 72-333
Range on HMM: 1-264/264
Sequence Identity: 52% (140 aa)

FQLLKVLGKGGYGKVFQVRKTTGKDSGKIF-AMKVLKKAKIVRNQKDTAHTKAERNILEAVQHPFIVDLHYAFQTGGKLYLILAYLGGGELFMHLEREGI
|..||||||| .||||.|.|   ||..|.. ||||||| .|. .    .|||.|||||. ..||||| |||.|||  |||... | .||||| || |...
FDFLKVLGKGSFGKVFLVKK---KDTQKWYYAMKVLKKDYIIQKN-QVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRR

FMEDTACFYLSEIVLALEHLHKLGIIYRD-LKPENIMLNKQGHVVLTDFGLCKES-LEEGSMTHTFCGTIEYMAPEIVSRSGHGKDVDWWS-LGALMYDM
| ||.| || .||.||.||||. .||||| ||||||.. |.||. |||||||||  . .. .| ||||| ||.|||| .  ||.| ||||. ||..|| |
FSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEM

LTGGPPFTAENRKKTIEKILKGKLSLP--PYLTHEARDLVRKLLKRHISARLGSGPEDATRIRKHPFF
..| ||| ......  .||. ...  |  ...  |..||...||..  . |||.||.||  |. ||.|
MCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase p70RSK.AA RSK 72-333 41 2.4e-129 436.02 In-house 1-271 (271) Show / Hide 
Range on Protein: 72-333
Range on HMM: 1-271/271
Sequence Identity: 41% (112 aa)

FQLLKVLGKGGYGKVFQVRKTTGKDSGKIFAMKVLKKAKIVRNQKDTAHTKAERNILEAVQHPFIVDLHYAFQTGGKLYLILAYLGGGELFMHLEREGIF
. |....|.| ..||. ..| ..||... .|||..|||...   .    ...||.||. ..||||| |||.||..||.|.|.  . ||.|| .| ... |
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR--VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF

MEDTACFYLSEIVLALEHLHKLGIIYRDLKPENIMLNKQ----GHVVLTDFGLCKESLEEGSMTHTFCGTIEYMAPEIVSRSGHGKDVDWWSLGALMYDM
 |. ..||..|| ||.|.||..||..|||||||| .  .    ||. ..|||. |... |  |. |||.|..|||||...| ||.. .||||.|.||| |
SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEM

LTGGPPFTAENRKKTIEKILKGKLSL-------PPYLTHEARDLVRKLLKRHISARLGSGPEDATRIRKHPFF
||| .|| . .|. . ..|.. || .       . ... || ||.|..|.|    |||.||... .|..||.|
LTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase p70RSK.AA RSK-Unclassified 72-333 43 1.2e-122 387.21 In-house 1-283 (283) Show / Hide 
Range on Protein: 72-333
Range on HMM: 1-283/283
Sequence Identity: 43% (125 aa)

FQLLKVLGKGGYGKVFQVRKTTGKDSGKIFAMKVLKKAKIVRNQKDTAHTKAERNILEAVQHPFIVDLHYAFQTGGKLYLILAYLGGGELFMHLE--REG
|   . .|.|  |||. |||   ||. .|.|||||.| |..| .| .     |.||.   .||||| | ..|||  .|||.. |  ||..| ||   .| 
FIKHRLIGQGDFGKVYLVRK---KDTQQIYAMKVLHKHKMIRHNK-IKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEK

IFMEDTACFYLSEIVLALEHLHKLGIIYRDLKPENIMLNKQGHVVLTDFGLCKES---------------------LEEGSMTHTFCGTIEYMAPEIVSR
 | || . ||.||...|||.|||...|||||||.||.| . ||| ||||.| ..                      ...|. |  |||| ||.|||.. |
CFCEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRR

SGHGKDVDWWSLGALMYDMLTGGPPFTAENRKKTIEKILKGKLSLP--PYLTHEARDLVRKLLKRHISARLGSGPEDATRIRKHPFF
 ||.| |||| || .|| || | ||. ..|.  | . |.|.....|   |.  ..|||..|||.|  . |||..  ||  |..||||
CGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase p70RSK.AA AktR 72-333 45 2.1e-118 399.69 In-house 1-268 (268) Show / Hide 
Range on Protein: 72-333
Range on HMM: 1-268/268
Sequence Identity: 45% (123 aa)

FQLLKVLGKGGYGKVFQVRKTTGK-DSGKIFAMKVLKKAKIVRNQKDTAHTKAERNILE-AVQHPFIVDLHYAFQTGGKLYLILAYLGGGELFMHLEREG
|...|.||||..|||. |.|   | |..|..|||..|| |  ....   ||  ||||.|  ..||||| |||.|||  ||..|. |  ||||| || ...
FHVYKCLGKGAFGKVYLVQK---KRDNQKQYAMKMIKK-KKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKK

IFMEDTACFYLSEIVLALEHLHKL-GIIYRDLKPENIMLNKQGHVVLTDFGLCK-ESLE-EGSMTHTFCGTIEYMAPEIVSR-SGHGKDVDWWSLGALMY
 | |..| || ..|.||||.||.   |||||||||||.| . ||| .||||| | .  . .  ....|||| ||||||.. .  ||.| ||||..|.. |
KFSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIY

DMLTGGPPFTAENRKKTIEKILKGK-LSLPPY--LTHEARDLVR-KLLKRHISARLGSGPEDATRIRKHPFF
 |.|| |||...|..  ..||..   .. |..  .. ...||.  |||...   |||.. .... |..||.|
EMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase p70RSK.AA MSK 75-328 41 6.30000000001e-111 374.82 In-house 1-277 (277) Show / Hide 
Range on Protein: 75-328
Range on HMM: 1-277/277
Sequence Identity: 41% (114 aa)

LKVLGKGGYGKVFQVRKTTGKDSGKIFAMKVLKKAKIVRNQKDTAHTKAERNILEAVQ-HPFIVDLHYAFQTGGKLYLILAYLGGGELFMHLEREGIFME
|||||.|||||.| .|| ...|.||..|||.|.|| .|  .| ..||..|| .||..| ||.|| ||||||.  ..||.. |. ||||| |. . . | |
LKVLGTGGYGKFFICRKCVHHDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFDE

DTACFYLSEIVLALEHLHKLGIIYRDLKPENIMLNKQ---GHVVLTDFGLCKESLEE-GSMTHTFCGTIEYMAPEIVSR-----SGHGKDVDWWSLGALM
. . ... |.|.|..|.|..|||.||||||||..  .   |||.|.|||. .. ...    ....|.|..|||||.. |     .|... .||||||...
SECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVIL

YDMLTGGPPFT--AENRK------KTIEK-ILKGKLSLP----PYLTHEARDLVRKLLKRHISARLGSGPEDATRIR
| ||||  ||.  .. |.      . | | |.||. |.|         .|.||...|| .  . ||| .. .|  ..
YTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase p70RSK.AA PKA 72-333 43 8e-111 374.48 In-house 1-263 (263) Show / Hide 
Range on Protein: 72-333
Range on HMM: 1-263/263
Sequence Identity: 43% (118 aa)

FQLLKVLGKGGYGKVFQVRKTTGKDSGKIFAMKVLKKAKIVRNQKDTAHTKAERNILEAVQHPFIVD-LHYAFQTGGKLYLILAYLGGGELFMHLEREGI
|.....||.| .|.| ..|.   |.||...|||.|||..|||  | . |.. |.||| ...|||||  . . ||.  .||... | .|||.| .| ..| 
FEIIQTLGTGSFGRVMLCRH---KHSGNYYAMKMLKKQEIVR-LKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGR

FMEDTACFYLS-EIVLALEHLHKLGIIYRDLKPENIMLNKQGHVVLTDFGLCKESLEEGSMTHTFCGTIEYMAPEIVSRS-GHGKDVDWWSLGALMYDML
| ...|.||   .|||||| ||.. |||||||||||...|.||. .||||  |. ...   | | ||| ||.||||.... |||| ||||.|| | | ||
FSNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK-VDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEML

TGGPPFTAE--NRKKTIEKILKGKLSLPPYLTHEA---RDLVRKLLKRHISARLGSGPEDATRIRKHPFF
.| |||...  .  .. |||..||.  |....  |   .||..||| . .. |.|.  ...  |..|..|
AGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase p70RSK.AA S_TKc 72-333 35 2.2e-102 347.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 72-333
Range on HMM: 1-231/231
Sequence Identity: 35% (97 aa)

FQLLKVLGKGGYGKVFQVRKTTGKDSGKIFAMKVLKKAKIVRNQKDTAHTKAERNILEAVQHPFIVDLHYAFQTGGKLYLILAYLGG--GELFMHLEREG
...|...|||..|||...|..    .|.|.|.|..|            |.. |..||.  .||.|| |...||. ..||... |..|  |.|| .... |
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

I------FMEDTACFYLSEIVLALEHLHKLGIIYRDLKPENIMLNKQGHVVLTDFGLCKESLEEGSMTHTFCGTIEYMAPEIVSRSGHGK-DVDWWSLGA
       | | .|.||. .|..|||..|..|||.||||||||.|..  |. ..||||...        .||||| .|||||..   |.||  .||||.| 
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LMYDMLTGGPPFTAENRKKTIEKILKGKLSLPPYLTHEARDLVRKLLKRHISARLGSGPEDA--TRIRKHPFF
..| ||.| |||   . .....||.          ..||.|..||.|..  . |..     .    |..||.|
ILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase p70RSK.AA Pkinase 72-333 29 3.8e-90 310.6 Pfam 1-293 (293) Show / Hide 
Range on Protein: 72-333
Range on HMM: 1-293/293
Sequence Identity: 29% (91 aa)

FQLLKVLGKGGYGKVFQVRKTTGKDSGKIFAMKVLKKAKIVRNQKDT---AHTKAERNILEAVQHPFIVDLHYAFQTGGKLYLILAYLGGG----ELFMH
.......|.|..|.|.. ..   |..|||.|.|..|| ..  ... |   .   .|  |.  ..||.|| |...|......|... |..||    .|| .
YHIGRKIGSGSFGCVYKCHH---KGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

LE--REGIF--MEDTACFYLSEIVLALEHLHKLGIIYRDLKPENIMLNKQGHV----VLTDFGLCKES-LEEGSMTHTFCGTIEYMAPEIVS-RSGHGKD
..  |.| |   |....||. .|. .||..|. |||.||||||||.....||.     ..||||.|   .  .| ..|||||..|||||..  ....|. 
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

VDWWSLGALMYDMLTGGPPFTAE------NRKKTIEKILKGKLSLPPYLT---------------------HEARDLVRKLLKRHISARLGSGPEDATRI
||.||.| ..| ||.| |||  .      . .. |..|....|. . . .                      |..|.....|..  . |..     |. |
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQI

RKHPFF
 .||.|
LQHPWF
Kinase p70RSK.AA S_TK_X 334-396 35 3.9e-22 80.79 SMART 1-79 (79) Show / Hide 
Range on Protein: 334-396
Range on HMM: 1-79/79
Sequence Identity: 35% (28 aa)

RHVKWDDVLA--RKGEPPITPAVV----NEEDVSQFDSKFTKQTPVDSPDDSMLSESANQ----------IFLGFTYVA
|.. ||....  .. |||..| .     ...|.|.|| .||..||...|||..||.|..|           |.|||||.
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase p70RSK.AA Pkinase_C 353-398 40 9.5e-15 55.14 Pfam 1-46 (46) Show / Hide 
Range on Protein: 353-398
Range on HMM: 1-46/46
Sequence Identity: 40% (19 aa)

AVVNEEDVSQFDSKFTKQTPVDS-PDDSMLSESANQIFLGFTYVAPS
 | ...|.| ||  ||...|.|. ||.. .|....  | |||||.|.
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase p70RSK.AA TyrKc 72-317 19 1.8e-12 -21.17 SMART 1-280 (280) Show / Hide 
Range on Protein: 72-317
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

FQLLKVLGKGGYGKVFQVRKTTGKDSGKIFAMKVLKKAKIVRNQKDTAHTKAERNILEAV--QHPFIVDLHYAFQTG-------GKLYLILAYLGGGELF
 .|.|.|| | .|.|.. . .         | |.||. .        .    | .|.  .  .|| || |. .  ..       . |.... |  .| | 
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

MHLEREGI-FMEDTACFYLSEIVLALEHLHKLGIIYRDLKPENIMLNKQGHVVLTDFGLCKESLEE-------GSMTHTF--CGT----IEYMAPEIVSR
 .| . .  .  .. . .   |    |.||. ..| |||   |........|  .||||...  ..          ...   .|     |  ||||    
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

SGHGKDVDWWSLGALMYDMLTGGPPFTAE------NRKKTIEKILKG-KLSLPPY--------LTHEARDLVRKLLKR---------HISARL
.      | || | .|. ..| | .   .      . .  ||.. .|  .  ||.         . |  .. ..  ..          |  ..
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF