Gene Spk363 (Sea Urchin)

Spk363

Species: Sea Urchin
Alias: Spk363, SPU_005457
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: urch
Subfamily: urchA

Sequence

Name Sequence Type Origin Length Description Download
Spk363.AA Protein None 783 None Fasta, JSON
Spk363.kin_dom Protein Kinase Domain None 199 None Fasta, JSON

Protein domain

Protein domains of Spk363.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Spk363.AA urchA 528-722 56 7.1e-152 493.12 In-house 1-208 (208) Show / Hide 
Range on Protein: 528-722
Range on HMM: 1-208/208
Sequence Identity: 56% (117 aa)

LGRGVAGTVSLFRHAVSKIPVAAKLVEYPG---------ECFRNEVRIHQAISGLPWFPTFYGSFDIEGDQAVLAMEFIGSESEDRSYTITDCLEKSMLK
|||||.||| |.||.....|||.|..|.|.         |||.||..|||.....||||||||...|..|....||||.|.|....|||||.||.|.|..
LGRGVYGTVHLYRHRQTDHPVALKVIELPKEYKKMRRKIECFQNEMQIHQVLGCEPWFPTFYGCCEICEDKVGMAMEFCGDEMTGESYTITWCLDKAMEM

TGPDLTRDEWFGVLNDVAEGLKALHSNGFLCNDLKEDNVLVVE-ESGRWRAKIIDLGWASEIATPF---VMPLDEEQIDFYRSGQGCGHIAPECVLDASP
..|.||||.|. |..|.|||||..|..|||||||||||.||.. |.|||||||||.|||.....||   .|..|..|..|||....|.||||||.|||.|
RQPALTRDQWMNVMLDIAEGLKVMHEKGFLCNDLKEDNCLVRKTEFGRWRAKIIDFGWACPCQMPFPACRMHFDQRQKQFYRYCHRCCHIAPECALDAQP

CSTSSDVY
||||||||
CSTSSDVY
Kinase Spk363.AA urch 528-725 43 2.7e-114 386.03 In-house 1-217 (217) Show / Hide 
Range on Protein: 528-725
Range on HMM: 1-217/217
Sequence Identity: 43% (95 aa)

LGRGVAGTVSLFRHAVSKIPVAAKLVEYPG-----------------ECFRNEVRIHQAISGLPWFPTFYGSFDIEGDQAVLAMEFIGSESEDRSYTITD
.|||..|.| |.||. .|.||| | ...|                  |.|..|...||..|| |.||.||| .||. |. .|.|||||......||....
IGRGTYGRVHLYRHRQTKQPVAIKMPCWPQNYTDMNEMEMEEWKANHERFTKEAMVHQLMSGHPYFPKFYGCVDID-DDLCLVMEFIGDKKTGKSYPLHW

CLEKS-MLKTGPDLTRDEWFGVLNDVAEGLKALHSNGFLCNDLKEDNVLVVE-ESGRWRAKIIDLGWASEIATPF-VMPLDEEQIDFYRSGQGCGHIAPE
|..|| |....|.|....|. ...|...|..|.|..|||.|||||||||... ..|||.|.|||.||......|| .|....|....|..|.|..|||||
CIHKSRMCMPNPHLSKWNWLNIAEDIVHGMMAMHDHGFLHNDLKEDNVLLEKRGHGRWHAVIIDFGWVCTMTMPFKMMHFPDEEMREYMHGHGYCHIAPE

CVLDASPCSTSSDVYSLG
||||..|||..|||||.|
CVLDGQPCSIASDVYSVG
Kinase Spk363.AA urch-unclassified 563-725 32 1.3e-41 144.53 In-house 52-215 (215) Show / Hide 
Range on Protein: 563-725
Range on HMM: 52-215/215
Sequence Identity: 32% (54 aa)

EVRIHQAISGLPWFPTFYGSFDIEGDQAVLAMEFIGSESEDRSYTITDCLEKSMLKTGPDLTRDEWFGVLNDVAEGLKALHSNGFLCNDLKEDNVLVVEE
|...|.. .. | ||  ||  ..|.. . ..|||.|  .  . |.  . .     |  | | . .|. .. |. .|..|.|. . | |||| .|.|.   
EAMVHRLFADHPYFPRCYGMVKHEDCPC-IVMEFLGDKQTYTVYPLCQWIHERH-KSNPALSKHHWINICMDICHGMHAMHEMDLLHNDLKSNNILLQWC

SG--RWRAKIIDLGWASEIATP---FVMPLDEEQIDFYRSGQGCGHIAPECVLDASPCSTSSDVYSLG
.   ||.|.|||.| .| .. |   .  .. |..   |..|    |.||| ||.  | |  ||.||||
DHDQRWHAYIIDFGMISTMTMPHKQRNFSDHEMRE--YMMGKIYHHMAPEIVLYGQPTSVYSDIYSLG
Kinase Spk363.AA urchC 560-728 31 2.8e-25 78.61 In-house 54-223 (223) Show / Hide 
Range on Protein: 560-728
Range on HMM: 54-223/223
Sequence Identity: 31% (54 aa)

FRNEVRIHQAISGLPWFPTFYGSFDIEGDQAVLAMEFIGSESEDRSYTITDCLE-KSMLKTGPDLTRDEWFGVLNDVAEGLKALHSNGFLCNDLKEDNVL
.. | |. | .|. |.|| .||   |...  .   ||||.    ..|   | .. .      |..       .  |. .|  ..|..| | || | ||||
CEKEARVGQMMSTCPYFPRMYGTVMIDENMCIVT-EFIGDKQQGKVYMLHDAMCPRKGCDPIPYVQKWNMVAIAEDIIRGVHFMHDFGLLHNDIKDDNVL

VVEESGRWRAKIIDLGWASEIATPFVMPLDEEQIDFYRSGQGCGHIAPECVLD--ASPCSTSSDVYSLGRFL
      || . |||.|  | .| |  .      .   . . |  ||||| |||   .  | .||.|| |  |
LEHRKERWHGCIIDMGMVSTMAYPPHQRGFNDVMPDHQKLYGFIHIAPE-VLDIDGCQVSVASDIYSVGVIL
Kinase Spk363.AA urchB 634-725 40 2.2e-16 55.46 In-house 120-212 (212) Show / Hide 
Range on Protein: 634-725
Range on HMM: 120-212/212
Sequence Identity: 40% (38 aa)

DVAEGLKALHSNGFLCNDLKEDNVLVVEESGRWRAKIIDLGWASEIATPFVM-PLDEEQIDFYRSGQGCGHIAPECVLDASPCSTSSDVYSLG
|.  |.  .|  | | |||| ||||      |. | ||| | .| |  |  |  . .|    |  |     |||| .|.  . | ||||.| |
DIVKGMMEFHDHGLLHNDLKNDNVLLEKRGHRYHAVIIDFGMVSTITAPLKMVEVPKELKMAYVHGEEADYIAPEVILHGQSTSISSDVFSVG
S_TKc Spk363.AA S_TKc 522-766 18 1.7e-10 -22.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 522-766
Range on HMM: 1-231/231
Sequence Identity: 18% (50 aa)

TRCSIELGRGVAGTVSLFRHAVSKIPVAAKLVEYPGECFRNEVRIHQAISGLPWFPTFYGSFDIEGDQAVLAMEFIGS--ESEDRSYTITDCLEKSMLKT
 .   ..|.|  |.| . ||  ..  || | .    | .|.|..|..   . |.  ..|..|.   |   . ||...    .          | . . | 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGD----------LFDYIKKR

GPD-----LTRDEWFGVLNDVAEGLKALHSNGFLCNDLKEDNVLVVEESGRWRAKIIDLGWASEIATPFVMPLDEEQIDFYRSGQGCGH-IAPECVLDAS
|.      ..  .   ..  ....|. .||.|..  ||| .|.|. |     . ||.| | | ..                ..  |  . .||| .    
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----------------TTFCGTPWYMAPEVL----

PCST-SSDVYSLG--------------RFLAIVGHAMRYDDFECFGTQIYLTDEGQRPTVQEIID--------QLY
. .. ..|..|.|                 ..  . .  ...  |  ..   |  .|||. |.          .  
GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Spk363.AA TKL 634-725 20 5e-07 21.36 In-house 140-276 (364) Show / Hide 
Range on Protein: 634-725
Range on HMM: 140-276/364
Sequence Identity: 20% (28 aa)

DVAEGLKALHSNG--------FLCNDLKEDNVLVVEES-----------GRWRAKIIDLGWASEIATPFVMPLDEEQID-----------FYRSGQGCGH
|.| |.  |||..         .  ||| .|.|| |               |..|| |.| . .. . . |   .  .             .. .   ..
DIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRW

IAPECVLDA---------------SPCSTSSDVYSLG
 |||.  ..               .. |...|||| |
MAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFG
Kinase Spk363.AA Trio 632-689 25 9.8e-07 12.6 In-house 101-159 (258) Show / Hide 
Range on Protein: 632-689
Range on HMM: 101-159/258
Sequence Identity: 25% (15 aa)

LNDVAEGLKALHSNGFLCNDLKEDNVLVVEESG-RWRAKIIDLGWASEIATPFVMPLDE
. .. |..  ||... |  |.| .|.....  . | . ||.|.| | .. .  | |...
MWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHH
Kinase Spk363.AA LISK-DD1 634-676 40 1e-06 20.07 In-house 131-174 (290) Show / Hide 
Range on Protein: 634-676
Range on HMM: 131-174/290
Sequence Identity: 40% (18 aa)

DVAEGLKALHSNGFLCNDLKEDNVLVVEE-SGRWRAKIIDLGWA
|.|..   |||.. .  |||  | || |  ...||.|..|.| |
DIACAMAYLHSKNIIHRDLKSKNILVDENGDSQWRIKVCDFGFA
Kinase Spk363.AA Ciliate-C7 633-658 50 2e-06 17.18 In-house 109-134 (164) Show / Hide 
Range on Protein: 633-658
Range on HMM: 109-134/164
Sequence Identity: 50% (13 aa)

NDVAEGLKALHSNGFLCNDLKEDNVL
.|.|.||   ||.... |||| || |
KDIAQGLYYIHSKNCVVNDLKMDNIL
Kinase Spk363.AA Dicty5 634-674 41 5e-06 16.8 In-house 112-149 (260) Show / Hide 
Range on Protein: 634-674
Range on HMM: 112-149/260
Sequence Identity: 41% (17 aa)

DVAEGLKALHSNGFLCNDLKEDNVLVVEESGRWRAKIIDLG
|.| ... ||| .    |||  |.|. |   .| .|||| |
DIAQSMRHLHSMNIIHRDLKSMNFLITE---NWKIKIIDFG
Kinase Spk363.AA urchB 566-598 45 3.6e-05 14.86 In-house 62-93 (212) Show / Hide 
Range on Protein: 566-598
Range on HMM: 62-93/212
Sequence Identity: 45% (15 aa)

IHQAISGLPWFPTFYGSFDIEGDQAVLAMEFIG
||| .|. |.|| |.|  || .    .| ||.|
IHQLMSDSPYFPKFWGTLDI-DNDLCQAQEFVG
Kinase Spk363.AA TKL 754-765 50 0.049276 3.13 In-house 353-364 (364) Show / Hide 
Range on Protein: 754-765
Range on HMM: 353-364/364
Sequence Identity: 50% (6 aa)

QRPTVQEIIDQL
.||. |||...|
KRPSFQEILKRL
Kinase Spk363.AA urchB 527-551 48 0.076854 2.79 In-house 6-30 (212) Show / Hide 
Range on Protein: 527-551
Range on HMM: 6-30/212
Sequence Identity: 48% (12 aa)

ELGRGVAGTVSLFRHAVSKIPVAAK
| |||  | | . ||   |.| | |
EIGRGTYGRVVIARHRQTKVPLAIK