Gene Spk398 (Sea Urchin)

Spk398

Species: Sea Urchin
Alias: Spk398
External Links:
Annotation:

Classification

Group: Other
Family: urch
Subfamily: urchA

Sequence

Name Sequence Type Origin Length Description Download
Spk398.AA Protein None 533 None Fasta, JSON
Spk398.kin_dom Protein Kinase Domain None 164 None Fasta, JSON

Protein domain

Protein domains of Spk398.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Spk398.AA urchA 287-486 54 7.2e-144 466.89 In-house 1-208 (208) Show / Hide 
Range on Protein: 287-486
Range on HMM: 1-208/208
Sequence Identity: 54% (113 aa)

LGSGANGTVHLYRHRATDHPIALKTFELPDDIKAMTRKAKAIQSEAFILDVLGREDCFPTFLGCLEISPGKIGLAMDFVGDTMTGES----WTLSR-XGM
||.|..|||||||||.||||.|||..|||...|.|.||....|.|..|..|||.|..||||.||.||...|.|.||.|.||.|||||    |.|..  .|
LGRGVYGTVHLYRHRQTDHPVALKVIELPKEYKKMRRKIECFQNEMQIHQVLGCEPWFPTFYGCCEICEDKVGMAMEFCGDEMTGESYTITWCLDKAMEM

RKLALSQQDGLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDAPY---FYRFSDENKEKYRRREVYVHIAPECALDDVL
|..||.... ....||||..|...||||||.|||||||||.|||..|||.|.|.|||.||||..|.   ...|. . |. || .  . |||||||||   
RQPALTRDQWMNVMLDIAEGLKVMHEKGFLCNDLKEDNCLVRKTEFGRWRAKIIDFGWACPCQMPFPACRMHFDQRQKQFYRYCHRCCHIAPECALDAQP

TSVSSDVF
 | ||||.
CSTSSDVY
Kinase Spk398.AA urch 287-489 38 1.3e-109 370.47 In-house 1-217 (217) Show / Hide 
Range on Protein: 287-489
Range on HMM: 1-217/217
Sequence Identity: 38% (84 aa)

LGSGANGTVHLYRHRATDHPIALKTFELPDDIKAMTR--------KAKAIQSEAFILDVLGREDCFPTFLGCLEISPGKIGLAMDFVGDTMTGES----W
.|.|..|.|||||||.|..|.|.|....|.....|..        . .....||...........||.|.||..|. ....|.|.|.||..||.|    |
IGRGTYGRVHLYRHRQTKQPVAIKMPCWPQNYTDMNEMEMEEWKANHERFTKEAMVHQLMSGHPYFPKFYGCVDID-DDLCLVMEFIGDKKTGKSYPLHW

TLS--RXGMRKLALSQQDGLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDAPY-FYRFSDENKEKYRRREVYVHIAPE
...  | .|....||... |. |.||.... ..|..|||.|||||||.||.|...|||.|||.|||..|....|. ...|.|| .. |.....|.|||||
CIHKSRMCMPNPHLSKWNWLNIAEDIVHGMMAMHDHGFLHNDLKEDNVLLEKRGHGRWHAVIIDFGWVCTMTMPFKMMHFPDEEMREYMHGHGYCHIAPE

CALDDVLTSVSSDVFQLG
|.||   .|..|||. .|
CVLDGQPCSIASDVYSVG
Kinase Spk398.AA urch-unclassified 287-489 28 1.1e-42 148.17 In-house 1-215 (215) Show / Hide 
Range on Protein: 287-489
Range on HMM: 1-215/215
Sequence Identity: 28% (61 aa)

LGSGANGTVHLYRHRATDHPIALK--TFELPDDIKAMTRKAKAIQ-----SEAFILDVLGREDCFPTFLGCLEISPGKIGLAMDFVGDTMTGESWTLSRX
.| |. | | ..|| ..  | . |       |..  | .. | .       || .  ...    ||  .|  ..  .  ...|.| ||  |.   .|.. 
IGKGTFGKVFMMRHQREAVPVKVKMIHEHHNDYDYEMRMQNKLLMHERIMKEAMVHRLFADHPYFPRCYGMVKHE-DCPCIVMEFLGDKQTYTVYPLCQW

GMRKL----ALSQQDGLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPT-GRWQAVIVDFGLACPCDA-PYFYRFSDENKEKYRRREVYVHIAPECA
  ..     ||| .  .  ..|| . .   ||.. | |||| .| ||.. .   || | | |||.. . .    . .|||. .. |.   .| |.|||  
IHERHKSNPALSKHHWINICMDICHGMHAMHEMDLLHNDLKSNNILLQWCDHDQRWHAYIIDFGMISTMTMPHKQRNFSDHEMREYMMGKIYHHMAPEIV

LDDVLTSVSSDVFQLG
|.   ||| ||.. ||
LYGQPTSVYSDIYSLG
Kinase Spk398.AA urchC 323-492 27 3.6e-13 38.76 In-house 47-223 (223) Show / Hide 
Range on Protein: 323-492
Range on HMM: 47-223/223
Sequence Identity: 27% (50 aa)

RKAKAIQS--EAFILDVLGREDCFPTFLGCLEISPGKIGLAMDFVGDTMTGESWTLSRXGMR-------KLALSQQDGLALALDIAKSLGRIHEKGFLMN
.|.. ..   || .. .. .   || ..| . |  . . .   |.||  .| .. |    |         . ..    .| | || .    .|  | | |
WKQNNGRCEKEARVGQMMSTCPYFPRMYGTVMID-ENMCIVTEFIGDKQQGKVYMLHDA-MCPRKGCDPIPYVQKWNMVAIAEDIIRGVHFMHDFGLLHN

DLKEDNCLL--RKTPTGRWQAVIVDFGLACPCDAP-YFYRFSDENKEKYRRREVYVHIAPECALD--DVLTSVSSDVFQLGRLL
| | || ||  ||    || ..|.| |.      | ..  |.|   .  ..   ..|||||  ||     .||.||..  | .|
DIKDDNVLLEHRKE---RWHGCIIDMGMVSTMAYPPHQRGFNDVMPDH-QKLYGFIHIAPEV-LDIDGCQVSVASDIYSVGVIL
Kinase Spk398.AA TESK 383-446 39 7.9e-13 36.39 In-house 88-155 (292) Show / Hide 
Range on Protein: 383-446
Range on HMM: 88-155/292
Sequence Identity: 39% (27 aa)

KLALSQQDGLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA----CPCDAP
.|.|| .  . ||.|||. .  .|.||    ||   ||| |. .   ..||. |||||    |  | |
ELHLSWTQKIHLAYDIARGMSYLHSKGVFHRDLTSKNCLVRQRDNNQYEAVVGDFGLARVLGCMPDPP
Kinase Spk398.AA urchB 344-446 38 1.8e-11 37.69 In-house 72-168 (212) Show / Hide 
Range on Protein: 344-446
Range on HMM: 72-168/212
Sequence Identity: 38% (40 aa)

FPTFLGCLEISPGKIGLAMDFVGDTMTGESWTLSRXGMRKLALSQQDGLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPC
|| |.| | |      .|  |||   ||  . |         ||   ..  | || | .  .|  | | |||| || || |    |. |||.|||..   
FPKFWGTLDID-NDLCQAQEFVGCKKTGIGYPL----HEPPPLSMCNVVDIAEDIVKGMMEFHDHGLLHNDLKNDNVLLEKRGH-RYHAVIIDFGMVSTI

DAP
 ||
TAP
S_TKc Spk398.AA S_TKc 278-533 14 2e-08 -53.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 278-533
Range on HMM: 1-231/231
Sequence Identity: 14% (41 aa)

FHKGGGDIFLGSGANGTVHLYRHRATDHPIALKTFELPDDIKAMTRKAKAIQSEAFILDVLGREDCFPTFLGCLEISPGKIGLAMDFVGDTMT--GESWT
....     .|.|| |.|.. ||. |..  |.|               . |..|  ||    . .   ..... .   ... . |...    .  |.  .
YEILR---KIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYC---DGDLGDLFD

LSRXGMRKLA---LSQQDGLALALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLACPCDAPYFYRFSDENKEKYRRREVYVH----I
. .   |.     ..  .   ..  |.. |  .|..|..  ||| .| || .      .  | |||||.                       ..     .
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------------------TTFCGTPWYM

APECALDDVLTSV-SSDV-------FQLGRLLTLMGGATTNADLTAIGNICRQSSQLC-------------RPSIDEVVA-----ELRRMM
|||        .  ..|.       . .    ..        .. .. .... |....             ||.. |. .      .   .
APEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Spk398.AA LISK 394-440 38 2.1e-08 23.2 In-house 106-152 (296) Show / Hide 
Range on Protein: 394-440
Range on HMM: 106-152/296
Sequence Identity: 38% (18 aa)

LALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA
.|||||...   |... .  |||  |||.|. . ..|.... |||.|
IALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFA
Kinase Spk398.AA IKK 284-329 23 2e-06 18.5 In-house 4-49 (297) Show / Hide 
Range on Protein: 284-329
Range on HMM: 4-49/297
Sequence Identity: 23% (11 aa)

DIFLGSGANGTVHLYRHRATDHPIALKTFELPDDIKAMTRKAKAIQ
.  ||.|| | | ..||..|.  .| |...  .  .....  . ..
CDRLGQGAFGNVYHWRHKKTGRKVAVKHCNHMSWMRCRWVWCREFE
Kinase Spk398.AA Ciliate-C7 395-440 47 4e-06 16.05 In-house 108-149 (164) Show / Hide 
Range on Protein: 395-440
Range on HMM: 108-149/164
Sequence Identity: 47% (22 aa)

ALDIAKSLGRIHEKGFLMNDLKEDNCLLRKTPTGRWQAVIVDFGLA
| |||  |  ||.|....|||| || |          ||. |||||
AKDIAQGLYYIHSKNCVVNDLKMDNILIDY----NGNAVVCDFGLA
Kinase Spk398.AA urchB 468-489 59 4e-06 18.43 In-house 191-212 (212) Show / Hide 
Range on Protein: 468-489
Range on HMM: 191-212/212
Sequence Identity: 59% (13 aa)

IAPECALDDVLTSVSSDVFQLG
||||  |..  ||.|||||  |
IAPEVILHGQSTSISSDVFSVG
Kinase Spk398.AA TKL 394-440 27 0.000469 10.51 In-house 137-201 (364) Show / Hide 
Range on Protein: 394-440
Range on HMM: 137-201/364
Sequence Identity: 27% (18 aa)

LALDIAKSLGRIHE--------KGFLMNDLKEDNCLLRKTPT----------GRWQAVIVDFGLA
.|||||. .   |         .. .  ||| .|.|. .  |            | . | ||||.
WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLS
Kinase Spk398.AA TKL 287-312 26 0.001708 8.46 In-house 1-34 (364) Show / Hide 
Range on Protein: 287-312
Range on HMM: 1-34/364
Sequence Identity: 26% (9 aa)

LGSGANGTVHLYRHRATD--------HPIALKTF
.|||. |.|.  ..| ..         ..| |.|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKF
Kinase Spk398.AA LISK 286-310 36 0.212995 0.07 In-house 1-25 (296) Show / Hide 
Range on Protein: 286-310
Range on HMM: 1-25/296
Sequence Identity: 36% (9 aa)

FLGSGANGTVHLYRHRATDHPIALK
 .|.|. | |   .||.|  ..|.|
EIGKGFFGKVYKGTHRQTGQVMAIK