Gene n1207 (Tetrahymena)

n1207

Species: Tetrahymena
Alias: n1207, 1207, 3827.m00857
External Links:
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
n1207.AA Protein None 737 None Fasta, JSON
n1207.NA RNA None 2214 None Fasta, JSON
n1207.kin_dom Protein Kinase Domain None 48 None Fasta, JSON

Protein domain

Protein domains of n1207.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase n1207.AA STE 183-227 34 6.5e-09 27.74 In-house 153-194 (359) Show / Hide 
Range on Protein: 183-227
Range on HMM: 153-194/359
Sequence Identity: 34% (16 aa)

LIYITYCLLNG-LYYMRQNKMFHGDISPDNIMIFQNRLKYIDLGSS
..||.. .| | |||  ...  | || |.||..     | .| | .
IAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVC
Kinase n1207.AA Ciliate-A5 178-214 43 2.7e-08 24.93 In-house 96-132 (275) Show / Hide 
Range on Protein: 178-214
Range on HMM: 96-132/275
Sequence Identity: 43% (16 aa)

WKEIDLIYITYCLLNGLYYMRQNKMFHGDISPDNIMI
..| .| ||  ||.. ..|..||. .|||| | || .
YNEQELWYIMDCLISVCMYLQQNNICHGDIRPQNICL
Kinase n1207.AA Ciliate-E2-Unclassified 180-250 25 1.2e-07 22.6 In-house 137-220 (352) Show / Hide 
Range on Protein: 180-250
Range on HMM: 137-220/352
Sequence Identity: 25% (22 aa)

EIDLI-----YITYCLLNGLYYMRQNK-MFHGDISPDNIMIFQN----RLKYIDLGSSH--LNNNKFYLKQ--YKKQFVNFNIMK
|   .     ......|.|| |. ...   | || |.||.. .|    ..| ||.|.|    .||... ..   |.|.  ...|.
EQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMW
Kinase n1207.AA S_TKc 43-387 10 2.1e-07 -68.44 SMART 1-231 (231) Show / Hide 
Range on Protein: 43-387
Range on HMM: 1-231/231
Sequence Identity: 10% (41 aa)

LLKLESLGKGGFGEVAVYYDHKIQQALAVKQFENEQHYYEEKERNSNCNFLQDRSKYFAAMLNYSDERKVIFYELGDCTLLEINNHFIQQNYLTTQIFKS
  .|. .|||.||.|   ...| ..  |.|.                                                                     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------

NEYSSVEKKHLKEEKKGLNKISIKKENK------------T--------MIAYQK------WKEIDLIYITYCLLNGLYYMRQNKMFHGDISPDNIMIFQ
 |    | . ||.  .  | . ..                .        .  ...        | .  ...| ....| |. ...  | |. |.||.. .
-EHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE

NRLKYIDLGSSHLNNNKFYLKQYKKQFVNFNIMKPKKNYTDNEISQNELYALGRTITHLCLYIQEEREDIIINRDLTLNSLRAKFDSFKTLLVQSQS---
 ..| .| |.. .                                                                            | .. .     
-HIKICDFGLARQL---------------------------------------------------------------------------TTFCGTPWYMA

---LKDYPSLSK-------------VLLKMQYPYDEDIQKIFQEIKQDNIQKKDVESKDQQQKNEEIVENAI-----KLTKQQTKRLSKKDSQK------
   |    . .|              .|  . |.. ..|..|. |.                      . |.      |.|  .||..  .  .      
PEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

----F
    |
CHPWF
Kinase n1207.AA MOK 188-226 46 8e-07 16.87 In-house 107-145 (283) Show / Hide 
Range on Protein: 188-226
Range on HMM: 107-145/283
Sequence Identity: 46% (18 aa)

YCLLNGLYYMRQNKMFHGDISPDNIMIFQNRLKYIDLGS
| |.  |  |  | .|| |. |.||.| |  ||  | ||
YQLCKSLDHMHRNGIFHRDVKPENILIKQDHLKLADFGS
Kinase n1207.AA Ciliate-E2 185-242 22 2e-06 18.33 In-house 164-226 (365) Show / Hide 
Range on Protein: 185-242
Range on HMM: 164-226/365
Sequence Identity: 22% (15 aa)

YITYCLLNGLYYMRQNK-MFHGDISPDNIMIFQNRLKYIDLGSSHLNNNK---------FYLKQYKKQ
..  |.. .| |. ...  .| || |.||..    .| ||.| |  ....          ..... |.
FYIACIILALEYLHSKNNIIHRDIKPENILF----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KN
Kinase n1207.AA DYRK2 46-72 55 3e-06 16.2 In-house 4-30 (318) Show / Hide 
Range on Protein: 46-72
Range on HMM: 4-30/318
Sequence Identity: 55% (15 aa)

LESLGKGGFGEVAVYYDHKIQQALAVK
|| .||| || |.  |||| .| .|.|
LEVIGKGSFGQVVKCYDHKTKQHVAIK
Kinase n1207.AA CMGC 186-227 25 6e-06 14.62 In-house 185-251 (513) Show / Hide 
Range on Protein: 186-227
Range on HMM: 185-251/513
Sequence Identity: 25% (17 aa)

ITYCLLNGLY--YMRQNK--MFHGDISPDNIMIFQN---------------------RLKYIDLGSS
..| .|.||   |. ...   .| |. | ||.| .|                     ||| .| |..
YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase n1207.AA DYRK1 43-82 35 9e-06 15.66 In-house 1-40 (321) Show / Hide 
Range on Protein: 43-82
Range on HMM: 1-40/321
Sequence Identity: 35% (14 aa)

LLKLESLGKGGFGEVAVYYDHKIQQALAVKQFENEQHYYE
..   ..||| || |.  |||. |.  |.|   | . .|.
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYN
Kinase n1207.AA IKK 189-222 33 2.1e-05 14.65 In-house 121-156 (297) Show / Hide 
Range on Protein: 189-222
Range on HMM: 121-156/297
Sequence Identity: 33% (12 aa)

CLLNGLYYMR-QNKMFHGDISPDNIMIF-QNRLKYI
..  |. ... ||.  | || |.|||.. .  .| |
DCCAGMHHLHSQNGIVHRDIKPGNIMCQKGEDGKTI
Kinase n1207.AA ULK 190-225 28 0.000219 11.32 In-house 139-187 (329) Show / Hide 
Range on Protein: 190-225
Range on HMM: 139-187/329
Sequence Identity: 28% (14 aa)

LLNGLYYMRQNKMFHGDISPDNIMIFQN-------------RLKYIDLG
.|||. ......  | || |.||.|  .             .||  | |
ILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG
Kinase n1207.AA DYRK2 190-235 32 0.000345 9.15 In-house 111-160 (318) Show / Hide 
Range on Protein: 190-235
Range on HMM: 111-160/318
Sequence Identity: 32% (16 aa)

LLNGLYYMRQNKMFHGDISPDNIMIFQ---NRLKYIDLGSSHLNNN-KFY
.|..|   ..|.  |.|  | ||.  |   . .| || |||   .  ..|
ILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIY
Kinase n1207.AA STE 43-89 19 0.000496 10.27 In-house 1-77 (359) Show / Hide 
Range on Protein: 43-89
Range on HMM: 1-77/359
Sequence Identity: 19% (15 aa)

LLKLESLGKGGFGEVAVYYDHK---------------IQQALAVKQFE---------------NEQHYYEEKERNSN
. ..| .|||.||.|   ..||                ..  |.|| .               .|.   ||...  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILK
Kinase n1207.AA IKK 43-79 27 0.000674 9.41 In-house 1-37 (297) Show / Hide 
Range on Protein: 43-79
Range on HMM: 1-37/297
Sequence Identity: 27% (10 aa)

LLKLESLGKGGFGEVAVYYDHKIQQALAVKQFENEQH
    . ||.|.||.|  .   |  .  |||..... .
WEMCDRLGQGAFGNVYHWRHKKTGRKVAVKHCNHMSW
Kinase n1207.AA ULK 43-73 28 0.009173 5.58 In-house 1-35 (329) Show / Hide 
Range on Protein: 43-73
Range on HMM: 1-35/329
Sequence Identity: 28% (10 aa)

LLKLESLGKGGFGEVAVYYDHKI----QQALAVKQ
  . . |||| || |   ...|     ... |.|.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKM
Kinase n1207.AA Ciliate-E2 43-93 14 0.010302 5.12 In-house 1-94 (365) Show / Hide 
Range on Protein: 43-93
Range on HMM: 1-94/365
Sequence Identity: 14% (14 aa)

LLKLESLGKGGFG-----EV-AV-------------------------YYDHKIQQALAVKQFENEQHYYEEKE------------RNSNCNFL
  ... .|.|.||     .|  |                         .|  ||..   ..|...|.| . |..            .. |....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNI
Kinase n1207.AA CMGC 43-86 16 0.010912 3.62 In-house 1-70 (513) Show / Hide 
Range on Protein: 43-86
Range on HMM: 1-70/513
Sequence Identity: 16% (12 aa)

LLKLESLGKGGFGEVAVYYD--------------HKIQQALAVKQFENEQHYYEEKE-------------R
  ... .|.| .|.|   .|              |. ..  |.| . |.. | |..              |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALR