Gene AqueK106 (A.queenslandica)

AqueK106

Species: A.queenslandica
Alias: AqueK106
External Links:
Annotation:

Classification

Group: CMGC
Family: CDKL

Sequence

Name Sequence Type Origin Length Description Download
AqueK106.AA Protein None 308 None Fasta, JSON
AqueK106.kin_dom Protein Kinase Domain None 207 None Fasta, JSON

Protein domain

Protein domains of AqueK106.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK106.AA CDKL 4-121 72 4.3e-87 295.64 In-house 1-118 (286) Show / Hide 
Range on Protein: 4-121
Range on HMM: 1-118/286
Sequence Identity: 72% (85 aa)

YEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLRQLKHGNLVNLLEVFRRKRKLHLVFEYCDHTVLNELEAHPRGLDETSA
|||..|.||||||||.|||||.||||||||||.||||||..||||.|||.||.|||| |.|||.|||||||||||||||||||||.||| .|.|.||   
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEEYPNGVDEHVV

KRIIWQTLQGVNYCHHQN
. ..||.|...|.|| .|
RKYMWQILKAINFCHKHN
Kinase AqueK106.AA CMGC 4-121 25 1.3e-48 157.32 In-house 1-202 (513) Show / Hide 
Range on Protein: 4-121
Range on HMM: 1-202/513
Sequence Identity: 25% (53 aa)

YEKISKIGEGSYGVVFKCRN--------------KDTGQIVAIKKFVESEDDPIIKK----------IALREIRMLRQLK----------------HGN-
||.|.|||||.||||.|||.              ..|..||||||. . . ... .|          .|||||..|..|.                | | 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

LVNLLEVFRRKR-----------------KLHLVFEYCDHTVLNELEAHP--------RGLDETS------------AKRII------WQTLQGVN--YC
.|.|...|..|                  .|.|||||.||. .. .. ..        ..|.|               | ..      .| |.|..  ||
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HHQN
| ..
HSHW
Kinase AqueK106.AA CDK 4-121 38 6.1e-48 151.37 In-house 1-128 (284) Show / Hide 
Range on Protein: 4-121
Range on HMM: 1-128/284
Sequence Identity: 38% (53 aa)

YEKISKIGEGSYGVVFKCRNKDTG-----QIVAIKKF-VESE----DDPIIKKIALREIRMLRQLKHGNLVNLLEVFRRK-----------RKLHLVFEY
|||. |||||.||||.|.|.|.||     ||||.||. .|.|    ..  .   |.||| .|..| | | |.|..|.  |           .|| .||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CDHTVLNELEAHPRGLDETSAKRIIWQTLQGVNYCHHQN
.||     ..           | ..|| |.|..|||...
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNW
Kinase AqueK106.AA CDC2 4-120 42 2.5e-41 124.41 In-house 1-122 (301) Show / Hide 
Range on Protein: 4-120
Range on HMM: 1-122/301
Sequence Identity: 42% (52 aa)

YEKISKIGEGSYGVVFKCRNKDTGQIVAIKKF-VESEDDP-IIKKIALREIRMLRQLK-HGNLVNLLEVFRRKRKLHLVFEYCDHTVLNELE-AHP--RG
|.|| |||||.||||.||....|.||||.||. .|.||.   .   |.|||  |  || | |.| | .|.   .|| .||||.|.   . ..   |    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LDETSAKRIIWQTLQGVNYCHHQ
...   | ...| ||||..||..
MPPQLVKSYMYQILQGVHFCHQR
Kinase AqueK106.AA Pkinase 4-121 31 5.7e-40 142.4 Pfam 1-128 (293) Show / Hide 
Range on Protein: 4-121
Range on HMM: 1-128/293
Sequence Identity: 31% (40 aa)

YEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALR--EIRMLRQLKHGNLVNLLEVFRRKRKLHLVFEYCDHT----VLNELEA--HP
|....|||.||.|.|.||..|.||.|||.|..  .....  .....|  ||.... |.| | | |...|..|.....|.|||...     | ..      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RGL--DETSAKRIIWQTLQGVNYCHHQN
...  .|  .|....|.|.|..||| ..
GCFYFSEWECKFYMYQILRGLEYCHSMG
Kinase AqueK106.AA CDK5 4-121 40 2.5e-39 121.58 In-house 1-118 (287) Show / Hide 
Range on Protein: 4-121
Range on HMM: 1-118/287
Sequence Identity: 40% (48 aa)

YEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLRQLKHGNLVNLLEVFRRKRKLHLVFEYCDHTVLNELEAHPRGLDETSA
|||. ||||| ||.|.| |||.|. |||.|.    ..|  .   |.||| .|. ||| | | |  |    .|| ||||.||      ..    ..|   .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KRIIWQTLQGVNYCHHQN
| ...| |.|. .||...
KSFMYQLLKGLAFCHEHH
Kinase AqueK106.AA CDKL 122-210 43 8.8e-35 116.35 In-house 198-286 (286) Show / Hide 
Range on Protein: 122-210
Range on HMM: 198-286/286
Sequence Identity: 43% (39 aa)

PLWPGRSDVDQLHLIIQTQGDLIPYHVKIFQESTYFKDTSIPCPDKREPISALYPQFS-QQILSFLEQGCLAMDPIARQTAEELLDHPVF
|||||.||.|||..|... |.||| | .||  . .|.. ..| . ..||.   ||. | .  |.|. ..|| |||  | |.|.|..|| |
PLWPGQSDIDQLYHIQKCLGPLIPRHQEIFSKNPFFHGMKFPEIEHMEPLEKRYPNKSNKKALDFM-KKCLHMDPDERMTCEQLMHHPYF
Kinase AqueK106.AA CDK7 4-118 37 1.3e-32 83.86 In-house 1-119 (288) Show / Hide 
Range on Protein: 4-118
Range on HMM: 1-119/288
Sequence Identity: 37% (45 aa)

YEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFV----ESEDDPIIKKIALREIRMLRQLKHGNLVNLLEVFRRKRKLHLVFEYCDHTVLNELEAHPRGLD
||||..|||| ...|.| . . |||||||||       || .  |   |.||| .|. ..| | ..|. .|  |  . |||.. |       .     | 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

ETSAKRIIWQTLQGVNYCH
    | .  .||||. |||
PAHIKAYMMMTLQGLEYCH
Kinase AqueK106.AA RCK 4-121 36 2.9e-32 99.45 In-house 1-125 (298) Show / Hide 
Range on Protein: 4-121
Range on HMM: 1-125/298
Sequence Identity: 36% (46 aa)

YEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLRQLK-HGNLVNLLEVFRRKR--KLHLVFEYCDHTVLNELEA---HPRG
|  |...|.|.||.|.| .||.||.||||||    .   .   . ||||. || |. | |...|.||.| .    |..||||.|  .   ..      . 
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKY

LDETS--AKRIIWQTLQGVNYCHHQN
| |.    | |. |.||| ...| ..
LPENQRSIKNIMYQILQGLAHMHKHG
Kinase AqueK106.AA CAMK 9-121 19 3.4e-30 93.92 In-house 1-199 (425) Show / Hide 
Range on Protein: 9-121
Range on HMM: 1-199/425
Sequence Identity: 19% (39 aa)

KIGEGSYGVVFKCRNKDTG------------QIVAIKK--------------------FVESEDD------PIIKKIALREIRMLRQ-------LKHGNL
..|.||.|.|..|..| |.            | ||||                     . . ...      |  .|  .|||.....       |.| |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNLLEVFR------------RKRK--------LHLVF---EYCDHT-----VLNELEAHPRG--------------LDETSAKRIIWQTLQGVNYCHHQN
..|.||.               .|        ...|.   |||.       ... . .|...              ..|  |.|...| ...|.||| .|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
Kinase AqueK106.AA STE 4-121 19 5.6e-24 81.62 In-house 1-172 (359) Show / Hide 
Range on Protein: 4-121
Range on HMM: 1-172/359
Sequence Identity: 19% (34 aa)

YEKISKIGEGSYGVVFKCRNKD---------------TGQIVAIKKFVESEDDPI---------------IKKIALREIRMLRQLK--HGNLVNLLEVFR
.|.|.|||.|..|.|.|..|..               ||.|.|||.   .....                ...  |.||.......  | | |. .  . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

RKR-------KLHLVFEYCDH-TVLNELE-AHPRGLD------------ETSAKRIIWQTLQG-VNYCHHQN
..        .|... ||.|  ..   ..  . .| .            |.  ..|. |.|.|  .| | ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH
Kinase AqueK106.AA STE20 4-121 28 2.5e-23 82.33 In-house 1-137 (288) Show / Hide 
Range on Protein: 4-121
Range on HMM: 1-137/288
Sequence Identity: 28% (39 aa)

YEKISKIGEGSYGVVFKCRNKDTGQI----VAIKKFVESEDDP--IIKKIALREIRMLRQLKHGNLVNLLEVFRRK----RKLHLVFEYCDH-TVLNELE
||.. |||.||||.|.|...|.||..    |||||   ...|.    ..  . ||....|.|| | |. .. . ..     .| .| |||.  ...  ..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---AHPR-----GLDETSAKRIIWQTLQGVNYCHHQN
    . .      ..|     |  ..||| .| |...
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNH
Kinase AqueK106.AA S_TKc 4-210 20 2.3e-19 71.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-210
Range on HMM: 1-231/231
Sequence Identity: 20% (60 aa)

YEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLRQLKHGNLVNLLEVFRRKRKLHLVFEYCDH---TVLNELEAHPRG---
||.. |||.|..|.|.|||.|.||.|||||.           . ..|||..|.. .| |.|.|..||.   .|..|.||||.   ...  .. ..|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LDETSAKRIIWQTLQGVNYCHHQN------------------------------------------------------------------PLWPGRSD
  ..|  |.....|......||| ..                                                                  |..|    
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP----

VDQLHLIIQTQGDLIPYHVKIFQESTYFKDTSIPCPDKREPISALYPQFSQQILSFLEQGCLAMDPIARQTAEELLD-------HPVF
  |......  |                                     |.. ..|... || .||  | || |.|        || |
--QMQMMFKKIG-------------------------------------SPEAKDFIRK-CLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK106.AA Pkinase_Tyr 4-85 27 5.6e-12 41.18 Pfam 1-91 (270) Show / Hide 
Range on Protein: 4-85
Range on HMM: 1-91/270
Sequence Identity: 27% (25 aa)

YEKISKIGEGSYGVVFKCRNK----DTGQIVAIKKFVESEDDPII--KKIALREIRMLRQL-KHGNLVNLLEVFR-RKRK--LHLVFEYCDH
 ... |.|||..|.|.|.. |    .|.. ||.|.      ..    ..  .||.....|| .| |.|.|. |   ...   . .|.||. |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH
Kinase AqueK106.AA CMGC 122-210 16 7e-10 27.7 In-house 341-513 (513) Show / Hide 
Range on Protein: 122-210
Range on HMM: 341-513/513
Sequence Identity: 16% (29 aa)

PLWPGRSD-----------VDQLHLIIQTQGDLIPYHVKIFQ--------ESTYFKDTSIP-------------------------------CPDKRE-P
||.||.|.           .|||..|... |    .  .  .        | .... .. |                                | ..  |
PLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKP

ISALYPQFS-----------------------------------QQILSFLEQGCLAMDPIARQTAEELLDHPVF
.. |.| ..                                   .| . .|.. .| .||  | |||. |.|| |
WKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKK-MLQYDPDKRITAEQALQHPYF
Kinase AqueK106.AA TyrKc 4-210 18 1e-07 -98.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-210
Range on HMM: 1-280/280
Sequence Identity: 18% (56 aa)

YEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLRQL--KHGNLVNLLEVFRRK-------RKLHLVFEYCDHTVLNE-LEA
 ... |.||| .|.|.|.. |   . ||.|.  |.     .. . .||.|....|  .| |.|.|. | . .         | .|.||..|  |.. | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDF-MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HPRGLDETSAKRIIWQTLQGVNYCHHQNPLWPGRSDVDQLHLI----------IQTQGDLIPYHVKI-------FQEST--------YFK-----DTS--
| . |       . ||  .| .| |..             ..|          .  ..     .|||       . ..         | .     ..   
HRPKLCMKDLLSFCWQIACGMEYLHSK-------------NCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTM

IP-------CPDKR-------------------EPISALYPQ-----FS-QQILSFLEQG---------------------------CLAMDPIARQTAE
.|       | ...                         ||       | |... ...||                           | . ||  | | .
LPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

ELLDHPVF
|.  |  |
EI--HECF
Kinase AqueK106.AA Pkinase 122-210 24 1e-06 24.84 Pfam 210-293 (293) Show / Hide 
Range on Protein: 122-210
Range on HMM: 210-293/293
Sequence Identity: 24% (23 aa)

PLWPGR----SDVDQLHLIIQTQGDLIPYHVKIFQESTYFKDTSIPCPDKREPISALYPQFSQQILSFLEQGCLAMDPIARQTAEELLDHPVF
|..||.    . .||...| .. |  ....     .  ||. .... .   .  . . .  |.  ..|.. .||..||  | |||..| || |
PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRHW-H---F-HWTF-HNWSEECKDFIK-WCLCKDPKKRPTAEQILQHPWF
Kinase AqueK106.AA STE20 177-210 38 2e-06 19.57 In-house 256-288 (288) Show / Hide 
Range on Protein: 177-210
Range on HMM: 256-288/288
Sequence Identity: 38% (13 aa)

QFSQQILSFLEQGCLAMDPIARQTAEELLDHPVF
..|..   |... || .||  | ||..|| || .
KWSPEFHDFVDK-CLQKDPEKRPTASQLLKHPFI
Kinase AqueK106.AA CDK7 188-210 34 3e-06 12.01 In-house 266-288 (288) Show / Hide 
Range on Protein: 188-210
Range on HMM: 266-288/288
Sequence Identity: 34% (8 aa)

QGCLAMDPIARQTAEELLDHPVF
.| ..|.|..| |. . | .| |
CGMWTMNPCKRWTCTQCLKMPYF
Kinase AqueK106.AA CDK 188-210 43 8e-06 14.42 In-house 262-284 (284) Show / Hide 
Range on Protein: 188-210
Range on HMM: 262-284/284
Sequence Identity: 43% (10 aa)

QGCLAMDPIARQTAEELLDHPVF
...|..||  | .||. |.|| |
NKMLCYDPKKRISAEQALQHPYF
Kinase AqueK106.AA STE 190-210 47 2.4e-05 14.99 In-house 337-359 (359) Show / Hide 
Range on Protein: 190-210
Range on HMM: 337-359/359
Sequence Identity: 47% (11 aa)

CLAMDPIARQTAEELLD--HPVF
|| .||  | ||..||   || .
CLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK106.AA CDK5 122-210 24 4.7e-05 11.38 In-house 198-287 (287) Show / Hide 
Range on Protein: 122-210
Range on HMM: 198-287/287
Sequence Identity: 24% (22 aa)

PLWPGRSDVDQLHLIIQTQGDLIPYHVKIFQESTYFK--DTSIPCPDKREPISALYPQFSQQILSFLEQGCLAMDPIARQTAEELLDHPVF
|| || .. ||| .| .  |     .     .   .|   .  |  . ... . . |. ... . .| |. | ..|  | .|.. | || |
PLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLL-QKMLQCNPNQRISAKAALHHPYF
Kinase AqueK106.AA RCK 170-210 39 7.5e-05 11.01 In-house 259-298 (298) Show / Hide 
Range on Protein: 170-210
Range on HMM: 259-298/298
Sequence Identity: 39% (16 aa)

PISALYPQFSQQILSFLEQGCLAMDPIARQTAEELLDHPVF
|.. | |. ||. .. .|  .|. ||  | ||...| || |
PLKQLIPNCSQDCIELMEK-MLQWDPQKRITAQQALQHPYF
Kinase AqueK106.AA CDK7 121-141 57 0.001737 4.67 In-house 200-220 (288) Show / Hide 
Range on Protein: 121-141
Range on HMM: 200-220/288
Sequence Identity: 57% (12 aa)

NPLWPGRSDVDQLHLIIQTQG
.|  || ||.|||  | || |
VPYLPGDSDIDQLTRIFQTLG
Kinase AqueK106.AA CDC2 191-210 50 0.002177 5.69 In-house 282-301 (301) Show / Hide 
Range on Protein: 191-210
Range on HMM: 282-301/301
Sequence Identity: 50% (10 aa)

LAMDPIARQTAEELLDHPVF
|. ||. | .|.| |.|| |
LQYDPQKRISAKEALQHPYF
Kinase AqueK106.AA CDK 122-141 50 0.009084 4.5 In-house 223-242 (284) Show / Hide 
Range on Protein: 122-141
Range on HMM: 223-242/284
Sequence Identity: 50% (10 aa)

PLWPGRSDVDQLHLIIQTQG
|| ||.|. |||..|... |
PLFPGDSEIDQLFKIFRICG
Kinase AqueK106.AA RCK 122-138 47 0.045733 2.02 In-house 212-228 (298) Show / Hide 
Range on Protein: 122-138
Range on HMM: 212-228/298
Sequence Identity: 47% (8 aa)

PLWPGRSDVDQLHLIIQ
||.|| | .||.. |..
PLFPGSSEIDQIFKICK
Kinase AqueK106.AA CAMK 188-210 39 0.048839 1.55 In-house 403-425 (425) Show / Hide 
Range on Protein: 188-210
Range on HMM: 403-425/425
Sequence Identity: 39% (9 aa)

QGCLAMDPIARQTAEELLDHPVF
...|  ||  | |.|. |.|| .
RKMLQVDPEKRMTIEQCLNHPWM