Gene AqueK112 (A.queenslandica)

AqueK112

Species: A.queenslandica
Alias: AqueK112
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK2

Sequence

Name Sequence Type Origin Length Description Download
AqueK112.AA Protein None 745 None Fasta, JSON
AqueK112.kin_dom Protein Kinase Domain None 297 None Fasta, JSON

Protein domain

Protein domains of AqueK112.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK112.AA DYRK2 309-605 60 1.9e-217 714.24 In-house 1-318 (318) Show / Hide 
Range on Protein: 309-605
Range on HMM: 1-318/318
Sequence Identity: 60% (192 aa)

YEIREIIGKGSFGQVVKVFDHKTNQHIALKIIRNKKRFHHQALVEVKILDSLRKRDRDNQYNIIHMFDYFYFRNHLCITFELMGMNLYELIKKNNFQGFS
||| |.|||||||||||..||||.||.|.|.||||||||.||..|..||. .|. |.||..|..||.||||||||.||||||..|||||.||||.|||||
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

ISLIRRFAYSMLQCLKILYRERIIHCDLKPENILLRLRGQSSIKVIDFGSSCYEHQ-RVYTYIQSRFYRSPEVILGLPYSMAIDMWSLGCILAELYTGYP
 .|.||||.|.||||. |....|||||||||||||. ...|.||||||||||.||| |.||||||||||.||||||..|.|||||||.|||.||||||||
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYP

LFPGENEVEQLACIIEIFGLPDPALLAEA-----QRKKLFFD--------------SRGNPRCVTNSKGKKRRPGSKDLSSAIK-TSDLLFLDFIRRCLV
|||||||..|.||..|..|.|.. ..  .      |.|.||.              |.  |....|..||.| ||||...|..| . | .|.|||.||..
LFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNSHCFEWYCTFMTDHSMEIPKHYKNRHGKRRPPGSKSWKSVLKGCEDENFIDFIKRCFE

WSASERMKPEEALQHAWI
| .||||.|..||.|.||
WDPSERMTPSQALKHPWI
Kinase AqueK112.AA DYRK 309-605 55 2.3e-192 645.33 In-house 1-320 (320) Show / Hide 
Range on Protein: 309-605
Range on HMM: 1-320/320
Sequence Identity: 55% (179 aa)

YEIREIIGKGSFGQVVKVFDHKTNQHIALKIIRNKKRFHHQALVEVKILDSLRKRDRDNQYNIIHMFDYFYFRNHLCITFELMGMNLYELIKKNNFQGF-
||| |.|||||||||||..|||||...|.|||||.||||.||. |.|||. |.. |.|..|...||.||||.||||||.|||. |||||..|.|.|||| 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

SISLIRRFAYSMLQCLKILYRE-RIIHCDLKPENILLRLR-GQSSIKVIDFGSSCYEHQRVYTYIQSRFYRSPEVILGLPYSMAIDMWSLGCILAELYTG
|..|.|.||...|.|||.|... .|||||||||||.|. . ..| ||||||||||.||||.||||||||||.||||||.||..||||||||||||||.||
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTG

YPLFPGENEVEQLACIIEIFGLPDPALLAEA--QRKKLFFDS------------RG------NPRCVTNSKGKKRRPGSKDLSSAIKTSDLLFLDFIRRC
.||||||||..|||||.|..|.| . .. ..  .||. |||.            .       .|.|. ...|..| ||.... ..... |..|.|||..|
WPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDCFMYCECDEWTKQNKITDHYMTPKCHPTKRGQRRPPGRRNWDPRHQCDDHQFKDFIKKC

LVWSASERMKPEEALQHAWI
|.|  ..|..|..|||| |.
LQWDPHKRITPSQALQHPWF
Kinase AqueK112.AA CMGC 309-605 21 8.49999999999e-122 402.3 In-house 1-513 (513) Show / Hide 
Range on Protein: 309-605
Range on HMM: 1-513/513
Sequence Identity: 21% (111 aa)

YEIREIIGKGSFGQVVKVFD--------------HKTNQHIALKIIRNKKRFHHQAL-------------VEVKILDSLR-----------KRDRDNQYN
||| . ||.|..|.|.| .|              |.||...|.|.|.|.. ...||.              |.|||  |.           . | ..  |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIHMFDYFYFRN-----------------HLCITFELMGMNLYELIKKNN--------------------------FQGFSISLIRRFAYSMLQCLK--I
|....|.||..|                 ||.. ||.|...||..||.|.                           . |.| .|| ..| .|..||   
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

LYRER--IIHCDLKPENILLRLRGQS------------------SIKVIDFGSSCYEHQR------------------------VYTYIQSRFYRSPEVI
. . .  |||.||||||||.  ....                   .|..|||.....|..                         ..|...|.||.||..
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LGLP----------YSMAIDMWSLGCILAELYTG--------YPLFPGENE-----------VEQLACIIEIFGLPDPALLAE-------AQRKKLFFDS
|| .          |. .|||||.|||.||.|||        .|||||..|           ..||..|....| |.  ..         ..... ... 
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNM

RG-------------------------NPRCVTNSKGKKRRPGSKDLSSAIKT--------------------------------SDLLFLDFIRRCLVW
 .                         |..  .|........  |.|   ...                                 | ...|.. ..|..
IKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

SASERMKPEEALQHAWI
  ..|...|.|||| ..
DPDKRITAEQALQHPYF
Kinase AqueK112.AA DYRK1 309-544 52 1.5e-107 363.64 In-house 1-238 (321) Show / Hide 
Range on Protein: 309-544
Range on HMM: 1-238/321
Sequence Identity: 52% (126 aa)

YEIREIIGKGSFGQVVKVFDHKTNQHIALKIIRNKKRFHHQALVEVKILDSLRKRDRDNQYNIIHMFDYFYFRNHLCITFELMGMNLYELIKKNNFQGFS
|||   ||||||||||| .||.. ...|.|||.||| |  ||..|...|. . |.|....|.|.|.   | ||||||. |||.  |||.|..  .|.| |
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

ISLIRRFAYSMLQCLKILYRE--RIIHCDLKPENILLRLRGQSSIKVIDFGSSCYEHQRVYTYIQSRFYRSPEVILGLPYSMAIDMWSLGCILAELYTGY
. |.|.||  |.. |  .      |||||||||||||.    | ||.|||||||   ||.| ||||||||||||.||..|.|||||||||||| |. || 
LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGE

PLFPGENEVEQLACIIEIFGLPDPALLAEAQRKKLFFD
||| | |||.|.  |.|. |.|  ... .| . . .|.
PLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFE
Kinase AqueK112.AA YAK 309-528 47 4.1e-102 345.55 In-house 1-224 (347) Show / Hide 
Range on Protein: 309-528
Range on HMM: 1-224/347
Sequence Identity: 47% (106 aa)

YEIREIIGKGSFGQVVKVFDHKTNQHIALKIIRNKKRFHHQALVEVKILDSLRKRDRDNQYN----IIHMFDYFYFRNHLCITFELMGMNLYELIKKNNF
| .  . |.| ||||||     ||  .| |.| |.  .  ||  |..|| .| ..   |  |    |. | |.| ..||.|. ||.  .||||..| |.|
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

QGFSISLIRRFAYSMLQCLKILYRERIIHCDLKPENILLRLRGQSSIKVIDFGSSCYEHQRVYTYIQSRFYRSPEVILGLPYSMAIDMWSLGCILAELYT
 |||..||| .  . |  . .|   .|||||||||||.|.   .  ||.|||||||.| . ||||||.|.|||||.|.. .|. .|||||||||.|||. 
CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFL

GYPLFPGENEVEQLACIIEIFGLP
| |.|||  | .|.  ||.. | |
GLPIFPGNSEYNQIKRIIDMLGYP
Kinase AqueK112.AA S_TKc 309-605 27 4.7e-87 296.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 309-605
Range on HMM: 1-231/231
Sequence Identity: 27% (87 aa)

YEIREIIGKGSFGQVVKVFDHKTNQHIALKIIRNKKRFHHQALVEVKILDSLRKRDRDNQYNIIHMFDYFYFRNHLCITFELMGM---NLYELIKKNNFQ
||| ..||||.||.| |. ..||... |.|||.       ... |..|| .       .  ||....|.|.  .||.. .|...    .|...|||.. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

G----FSISLIRRFAYSMLQCLKILYRERIIHCDLKPENILLRLRGQSSIKVIDFGSSCYEHQRVYTYIQSRFYRSPEVILGLPYSM-AIDMWSLGCILA
|    |.   .|...| ... |. . . .|||.|||||||||       ||..|||...      .|.. ...|..|||.   .|.  ..|.||.||||.
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELYTGYPLFPGENEVEQLACIIEIFGLPDPALLAEAQRKKLFFDSRGNPRCVTNSKGKKRRPGSKDLSSAIKTSDLLFLDFIRRCLVWSASERMKPEEAL
|...|||.||      |.. .... |                                                .  ..||||.||..  ..|.   |||
EMLCGYPPFP------QMQMMFKKIG------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EAL

Q-------HAWI
|       | |.
QDEWDIKCHPWF
Kinase AqueK112.AA HIPK 309-544 42 2.7e-75 236.48 In-house 1-238 (329) Show / Hide 
Range on Protein: 309-544
Range on HMM: 1-238/329
Sequence Identity: 42% (102 aa)

YEIREIIGKGSFGQVVKVFDHKTNQHIALKIIRNKKRFHHQALVEVKILDSLRKRDRDNQYNIIHMFDYFYFRNHLCITFELMGMNLYELIKKNNFQGFS
||. |..|.| ||||||   . ||  .|.||..|   .  |  .||.||  |.. . | .|... ....|  .|| |. ||..  |||.  |.|.|    
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENAD-EYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLP

ISLIRRFAYSMLQCLKILYRERIIHCDLKPENILL--RLRGQSSIKVIDFGSSCYEHQRVY-TYIQSRFYRSPEVILGLPYSMAIDMWSLGCILAELYTG
.  ||      |  |. |    .|| |||||||.|    |    .|||||||  .  . |  ||.|||.|| ||.|||||.  ..|||||||..|||. |
LKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLG

YPLFPGENEVEQLACIIEIFGLPDPALLAEAQRKKLFFD
 ||.|| .| .|   |..  .|| . || .| .|. |||
WPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFD
Kinase AqueK112.AA Pkinase 309-605 28 2.9e-62 217.96 Pfam 1-293 (293) Show / Hide 
Range on Protein: 309-605
Range on HMM: 1-293/293
Sequence Identity: 28% (92 aa)

YEIREIIGKGSFGQVVKVFDHKTNQHIALKIIRNKKRFH--HQALV---EVKILDSLRKRDRDNQYNIIHMFDYFYFRNHLCITFELMGM-----NLYEL
|.| ..||.||||.| |  ...|..  |.|||. ... .  .|...   |..|. .|.        ||. ..|.|. ..|... .|....      |...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

IK---KNNFQGFSISLIRRFAYSMLQCLKILYRERIIHCDLKPENILLRLRGQS--SIKVIDFGSSC---YEHQRVYTYIQSRFYRSPEVIL-GLPYSMA
|.   ...|  ||   .....| .|. |. .....|||.||||||||.  .|.   ..|..|||...   | ... .|.  ...|..||||. | .|. .
ISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPK

IDMWSLGCILAELYTGYPLFPGE----NEVEQLACIIEIFGLPDPALLAEAQRKKLFFDSRGNPRCVTNSKGKKRRPGSKDLSSAIKTSDLLFLDFIRRC
.||||.||||.|...|.|.|||.    | ..|...| .| | | .    .  .. .||  |  . .             . ..   .  .  ..|||..|
VDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------------F-HWTF-HNWSEECKDFIKWC

LVWSASERMKPEEALQHAWI
| .  ..|  .|..||| |.
LCKDPKKRPTAEQILQHPWF
Kinase AqueK112.AA CDK 309-605 26 4.2e-60 190.91 In-house 1-284 (284) Show / Hide 
Range on Protein: 309-605
Range on HMM: 1-284/284
Sequence Identity: 26% (90 aa)

YEIREIIGKGSFGQVVKVFDHKTN-----QHIALKIIR---N-----KKRFHHQALVEVKILDSLRKRDRDNQYNIIHMFDYFYFR-----------NHL
||. | || |..|.| |  |..|.     | .||| ||   .     |  | . |. |...|  |         ||.  .| ..             | |
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-------HPNIVKLHDVCHTKNMDRNNKDKHENKL

CITFELMGMNLYELIKKNNFQGFSISLIRRFAYSMLQCLKILYRERIIHCDLKPENILLRLRGQSS---IKVIDFGSSCYEH--------QRVYT-YIQS
 . || | . |.....           |. . . .|. |  . . .|.| |||| |||.  .|.     .|. ||| ..  .        .|.||  .  
YMVFEYMDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVT

RFYRSPEVIL-GLPYS--MAIDMWSLGCILAELYT---GYPLFPGENEVEQLACIIEIFGLPDPALLAEAQRKKLFFDSRGNPRCVTNSKGKKRRPGSKD
. ||.||. |    ||   .|||||.|||.||..|   . |||||..| .|| .|..|.| |..    .     ..                        
LWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY------------------------

LSSAIKTSDLLFLDFIRRCLVWSASERMKPEEALQHAWI
             |.. ..|.   . |.. |.|||| . 
-------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase AqueK112.AA DyrkP 309-526 41 1.2e-59 194.9 In-house 1-222 (323) Show / Hide 
Range on Protein: 309-526
Range on HMM: 1-222/323
Sequence Identity: 41% (93 aa)

YEIREIIGKGSFGQVVKVFDHKTNQHIALKIIRNKKRFHHQALVEVKILDSLRKRDRDNQYNIIHMFDYFYFRNHLCITFELMGMNLYELIKKN----NF
| | | .|   | . ..  | .||| . .||| | | .  |.. |.|.|  .         |.....|||| . || |  ||.  ||||  | |      
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQQ

QGFSISLIRRFAYSMLQCLKILYRERIIHCDLKPENILLRLRGQSSIKVIDFGSSCYEHQRVYTYIQSRFYRSPEVILGLPYSMAIDMWSLGCILAELYT
. | .  . .    .|  |  .   |.|||||||||||.. . .  .|.|||||||. |  .  |.||| || ||||.|  |   |||||||||||||.|
RYFTVGRLQKITQQILIALDYIHSLRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWT

GYPLFPGENEVEQLACIIEIFG
|  ||  .|    || .| | |
GNVLFQNDNIQGLLARVIGIIG
Kinase AqueK112.AA PRP4 309-511 39 1.6e-57 197.4 In-house 1-207 (320) Show / Hide 
Range on Protein: 309-511
Range on HMM: 1-207/320
Sequence Identity: 39% (82 aa)

YEIREIIGKGSFGQVVKVF-DHKTNQHIALKIIRNKKRFHHQALVEVKILDSLRKR--DRDNQYNIIHMFDYFYFRNHLCITFELMGMNLYELIKKN-NF
|..   .|.| |. |..     ..|. .| |||||.   |   | |. ||  |     |..  . .. ||. |..|.|.|. || | ||| |..||    
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

QGFSISLIRRFAYSMLQCLKILYRERIIHCDLKPENILLRLRGQSSIKVIDFGS-SCYEHQRVYTYIQSRFYRSPEVILGLPYSMAIDMWSLGCILAELY
 |...  .| .|. ..  || | .  |.| |.|| |||     .. .| .|||| |  . . .  | .|||||.||.|.| ||  .||||| || |.|||
VGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILVNES-KNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELY

TGYPLFPG
||  .|||
TGKIMFPG
Kinase AqueK112.AA CLK 309-443 37 8.4e-53 156.26 In-house 1-147 (350) Show / Hide 
Range on Protein: 309-443
Range on HMM: 1-147/350
Sequence Identity: 37% (55 aa)

YEIREIIGKGSFGQVVKVFDHKT-NQHIALKIIRNKKRFHHQALVEVK-ILDSLRKR-DRDNQYN--IIHMFDYFYF-RNHLCITFELMGMNLYELIKKN
|||    | | || ||.. |||  ....||||||| ...  .| ||.. |. .. .  | .|.|   ...|.|.| .  .| || |||.| ..|...|.|
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

N------FQGFSISLIRRFAYSMLQCLKILYRERIIHCDLKPENILL
|      .... |. ||..||  .. .| |   ...| |||||||..
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICF
Kinase AqueK112.AA CLK 451-605 36 3.4e-42 123.83 In-house 186-350 (350) Show / Hide 
Range on Protein: 451-605
Range on HMM: 186-350/350
Sequence Identity: 36% (60 aa)

IKVIDFGSSC---YEHQRVYTYIQSRFYRSPEVILGLPYSMAIDMWSLGCILAELYTGYPLFPGENEVEQLACIIEIFGLPDPALLAEAQR----KKLFF
|.||||||     ..|   .| ...| || |||||||..|   | || |||| |||||. ||.. ...| || . .| |.| |   . . |    |. .|
ICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQKYF

DSRGNPRCVTNSKGKKRRPGSKDLSSAIKTSDL---LFLDFIRRCLVWSASERMKPEEALQHAWI
  ..    ..||.|.. .   | | .  .  |.    . | ||..|    | |..  .|||| . 
YHNRLDWDWHNSDGRYVMENCKPLKQYMDCKDPEHRQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase AqueK112.AA DyrkP 562-605 38 6.6e-10 28.1 In-house 280-323 (323) Show / Hide 
Range on Protein: 562-605
Range on HMM: 280-323/323
Sequence Identity: 38% (17 aa)

PGSKDLSSAIKTSDLLFLDFIRRCLVWSASERMKPEEALQHAWI
|    |   ..| |..|.||.|.||      |    ||||| |.
PKHSNLRARLRTDDHMFIDFVRQCLQIDFTRRPTAKEALQHPWF
Kinase AqueK112.AA TyrKc 309-603 14 7.8e-08 -95.94 SMART 1-280 (280) Show / Hide 
Range on Protein: 309-603
Range on HMM: 1-280/280
Sequence Identity: 14% (49 aa)

YEIREIIGKGSFGQVVK-VFDHKTNQHIALKIIRNKKRFHHQALV-EVKILDSL--RKRDRDNQYNIIHMFDYFYFR-------NHLCITFELMGM-NLY
 .  ...| | ||.|.| . .    .  | | ... .   ....  | .|. .|  .        ||. .. .             |.| .|.|   .| 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA---REDFMREARIMCKLGGHHP------NIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

ELIKKNNFQGFSISLIRRFAYSMLQCLKILYRERIIHCDLKPENILLRLRGQSSIKVIDFGSSCYEHQR-------VYTYI----QSR-----FYRSPEV
. ..|.  . .. .    |..   .    | . ..|| ||   |.|.  ..   .|. ||| | . .          |       ...        .||.
DYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

ILGLPYSMAIDMWSLGCILAELYT-GYPLFPGE----NEVEQLACIIEIFGLPDPALL----AEAQRKKLFFDSRGNPRCVTNSKGKKRRPGSKDLSSAI
|    .. . | || |  . |..| | .  ||.     . ...   ..  . ...       .                                  .  
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------------F-V

KTSDLLFLDFIRRCLVWSASERMKPEEALQHA
  .| ..   ...|    ...|   .|  .  
CCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK112.AA DYRK1 578-605 39 5.8e-05 12.82 In-house 294-321 (321) Show / Hide 
Range on Protein: 578-605
Range on HMM: 294-321/321
Sequence Identity: 39% (11 aa)

FLDFIRRCLVWSASERMKPEEALQHAWI
| | |.| | .   .|..| .||||...
FKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase AqueK112.AA HIPK 578-605 32 0.000336 8.58 In-house 302-329 (329) Show / Hide 
Range on Protein: 578-605
Range on HMM: 302-329/329
Sequence Identity: 32% (9 aa)

FLDFIRRCLVWSASERMKPEEALQHAWI
| .  .. ..| | .|. | |||.| ..
FVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase AqueK112.AA PRP4 578-605 35 0.002693 8.02 In-house 293-320 (320) Show / Hide 
Range on Protein: 578-605
Range on HMM: 293-320/320
Sequence Identity: 35% (10 aa)

FLDFIRRCLVWSASERMKPEEALQHAWI
| |.. .||.   . |  ..|||.|  |
FKDLLDKCLMLDPKKRITCNEALKHPFI
Kinase AqueK112.AA YAK 577-605 44 0.023564 3.36 In-house 319-347 (347) Show / Hide 
Range on Protein: 577-605
Range on HMM: 319-347/347
Sequence Identity: 44% (13 aa)

LFLDFIRRCLVWSASERMKPEEALQHAWI
.|.|||   |     || ||  | ||  |
CFIDFINQLLQLNPRERWKPMQAMQHPFI