Gene AqueK114 (A.queenslandica)

AqueK114

Species: A.queenslandica
Alias: AqueK114
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: HIPK

Sequence

Name Sequence Type Origin Length Description Download
AqueK114.AA Protein None 599 None Fasta, JSON
AqueK114.kin_dom Protein Kinase Domain None 328 None Fasta, JSON

Protein domain

Protein domains of AqueK114.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK114.AA HIPK 69-396 55 1.5e-166 528.98 In-house 1-329 (329) Show / Hide 
Range on Protein: 69-396
Range on HMM: 1-329/329
Sequence Identity: 55% (183 aa)

YDVLDRLGRGTFGQVVRAWKKNTSEIVAIKILKSTPSYAKQGQMEVDVLSKLSRLSPDEGSFVKAYESFQHHGHICIVFELLHINLYDYLKQSRFDPLPL
|.||. ||||||||||..||. |.|.|||||||  |.||.|||.|| .|..|| ...||  ||.||| |.|. |.|.|||.|  ||||..|| .| ||||
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLPL

KYIRPIAQQVLCCLEKLASLGLVHADLKPENIMLVDPQRYPFKVKVIDFGSAMSRDKTSPSCYLQSRYYRAPEVILGVNFNEGIDMWSLGCVLAELYLGW
|.|||| ||||  | || .|||.||||||||||||||.| |..|||||||||  . |.  . |||||||||||.|||. |.| .||||||||.|||.|||
KHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLGW

PLFPGASEFDQITYICQTLGPLPHHLMRNITKATRFF--NCDPVTSTWSLKSISQYTQETGIQSKESRKYIFRSLLDMNHLPPLAAGIDNREAILTSVDR
||.|||.|.||| ||||| .    ||.   .|..|||    .   . | || | .. |.|...||| ||||| .| || .   .    .  .     .||
PLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQSKFRPWRLKHIEEHEQQTSVKSKEARKYIFNCLDDMPEV-NMLVDPERQDYRVEKIDR

MEFISLLSRMLSLDPTQRIRPLSALQSPFI
 ||...| .|...|. .|| |. ||..||.
REFVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase AqueK114.AA DYRK 69-396 37 3e-140 472.23 In-house 1-320 (320) Show / Hide 
Range on Protein: 69-396
Range on HMM: 1-320/320
Sequence Identity: 37% (125 aa)

YDVLDRLGRGTFGQVVRAWKKNTSEIVAIKILKSTPSYAKQGQMEVDVLSKLSRL-SPDEGSFVKAYESFQHHGHICIVFELLHINLYDYLKQSRFDPL-
| .|. .|.|.|||||..|...| |.|||||... .....|.| |.  |..|..  . |.  .|..|..|.|..| ||||||| .|||..||. .|... 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

PLKYIRPIAQQVLCCLEKLASL-GLVHADLKPENIMLVDPQRYPFKVKVIDFGSAMSRDKTSPSCYLQSRYYRAPEVILGVNFNEGIDMWSLGCVLAELY
.|...|..|||.| || .|...  ..|.|||||||||..| | .  .|||||||.   ..   . |.|||.|||||||||  ... ||||||||.||||.
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQP-RNKSTIKVIDFGSSCFEHQ-RIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELF

LGWPLFPGASEFDQITYICQTLGPLPHHLMRNI--TKATRFFNCDPVTSTWSLKSISQYTQETGIQSKESRKYIFRSLLDMNHLPPLAAGIDNREAILTS
.|||||||..|.||...|...||. |......   .....||.|        ..   . ...... ... ......   .      .  |  | .. .. 
TGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC--------FMYCECDEWTKQNKITDHYMTPKCHPTKR--GQRRPPGRRNWDPRHQ-

VDRMEFISLLSRMLSLDPTQRIRPLSALQSPFI
 |. .|. .. ..| .||..|| |  ||| |..
CDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase AqueK114.AA CMGC 69-396 20 1.8e-98 324.24 In-house 1-513 (513) Show / Hide 
Range on Protein: 69-396
Range on HMM: 1-513/513
Sequence Identity: 20% (109 aa)

YDVLDRLGRGTFGQVVRAWKKNTS--------------EIVAIKILKSTPSYAKQGQ-------------MEVDVLSKLS-RLSPDE-----------GS
|......|.||.|.|.... |.|               ||||||..|. . |  |..              |.  | .|. .  | .             
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

-FVKAYESFQHHG-----------------HICIVFELLHINLYDYLKQSR--FDP------------------------LPLKYIRPIAQQVLCCLE--
  || |..|.|..                 |...|||..  .||.|.|. .  . .                        ... .|| ...|.|..|.  
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

KLASLG--LVHADLKPENIMLVDPQRYP----------------FKVKVIDFGSAMSRDKTSP-----------------------SCYLQSRYYRAPEV
 . | .   .| |||||||.. .  ...                ...|..|||.| . .. |                        . | ..|.|||||.
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

ILG----------VNFNEGIDMWSLGCVLAELYLG--------WPLFPGASE-----------FDQITYICQTLGPLPHHLMRN-------ITKATRFFN
.||           .....|||||.||..||.|.|        .||||| ||            ||.  |...||. . .....        ..   ..|
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPN

CDP------------VTSTWSLKSISQYTQETGIQSKESRKYIFRSL-LDMNHLPPLA---------------AGIDNREAILTS---------------
. .                       |  ..|...|.  |.||.. . . . . .|.                | .. .. |. .               
MIKLPWYNKFPKKWNW----------Q--TMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVF-NW-IY-EEKFKSHKFNHQFKRK

VDRMEFISLLSRMLSLDPTQRIRPLSALQSPFI
 .  ..| ||..|| .||..|| .  ||| |..
CCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase AqueK114.AA YAK 69-336 37 1.3e-81 277.02 In-house 1-286 (347) Show / Hide 
Range on Protein: 69-336
Range on HMM: 1-286/347
Sequence Identity: 37% (108 aa)

YDVLDRLGRGTFGQVVRAWKKNTSEIVAIKILKSTPSYAKQGQMEVDVLSKL-SRLSPDEGS----FVKAYESFQHHGHICIVFELLHINLYDYLKQSRF
| ||| ||.|||||||   .  | |..|.|..|. . |  |.  |. .|  |  .  |..      ... | .| |  | |.|||.| .|||.|||| .|
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

DPLPLKYIRPIAQQVLCCLEKLASLGLVHADLKPENIMLVDPQRYPFKVKVIDFGSAMSRDKTSPSCYLQSRYYRAPEVILGVNFNEGIDMWSLGCVLAE
  .    ||    |.|  .  |..  ..| |||||||||  | . |  .|.|||||.    |.    | |.|.||.||.|... .   ||||||||..||
CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNK-P-EIKIIDFGSSCQEKKMV-YTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAE

LYLGWPLFPGASEFDQITYICQTLGPLPHHLMRNITKATRFFNCDPV----------------TSTWSLKSISQYTQETGIQSKESRKY
|.|| |.|||.||..||. |  .||  |  ..      ...| |                        .|.   |  . .|| |||..|
LFLGLPIFPGNSEYNQIKRIIDMLGYPPSWMIDQGRFKNKYFHCHDGSNSDDNNNNNNNNNGKPYYYIFKTKQDYQIDEKIQLKESKTY
Kinase AqueK114.AA DYRK2 69-307 39 2.6e-77 250.88 In-house 1-243 (318) Show / Hide 
Range on Protein: 69-307
Range on HMM: 1-243/318
Sequence Identity: 39% (97 aa)

YDVLDRLGRGTFGQVVRAWKKNTSEIVAIKILKSTPSYAKQGQMEVDVLSKLSRLSPDEGS-FVKAYESFQHHGHICIVFELLHINLYDYLKQSRFDPLP
| .|  .|.| |||||..  . | . ||||..     ...| ..|. .|....|  .|. .  |.  ..|   .|.||.|||| .|||.|.|.  |  . 
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

LKYIRPIAQQVLCCLEKLASLGLVHADLKPENIMLVDPQRYPFKVKVIDFGSAMSRDKTSPSCYLQSRYYRAPEVILGVNFNEGIDMWSLGCVLAELYLG
|. .|. |...| ||. |    ..|.|||||||.|   |. .  .|||||||    .      | |||.|||||||||  ..  |||||.||..|||| |
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLK--QWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTG

WPLFPGASEFDQITYICQTLGPLPHHLMRNI-----TKATRFFNC
 |||||  |.||. ..   ||  | ... .      ...  |||.
YPLFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNS
Kinase AqueK114.AA DYRK1 69-396 36 1.6e-76 260.53 In-house 1-321 (321) Show / Hide 
Range on Protein: 69-396
Range on HMM: 1-321/321
Sequence Identity: 36% (122 aa)

YDVLDRLGRGTFGQVVRAWKKNTSEIVAIKILKSTPSYAKQGQMEVDVLSKLSRLSPDEG-SFVKAYESFQHHGHICIVFELLHINLYDYLKQSRFDPLP
|..   .|.| |||||.|. . . | |||||.|   ..  | |.|. .|  . .  ...    |.  . | .  |.|.|||||  |||| |.   |    
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

LKYIRPIAQQVLCCLEKLAS--LGLVHADLKPENIMLVDPQRYPFKVKVIDFGSAMSRDKTSPSCYLQSRYYRAPEVILGVNFNEGIDMWSLGCVLAELY
|  .| .|||..  |  ...  | ..| |||||||.|. |.|   ..|.|||||.   ..     |.|||.||.|||.||....  ||||||||.| |. 
LNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRS--AIKIIDFGSSCQLGQRI-YQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMH

LGWPLFPGASEFDQITYICQTLGPLPHHLMRNITKATRFFNCDPVTSTWSLKSISQYTQETGIQSKESRKYIFRSLLDMNHLPPLAAGIDNREAILTSVD
 | ||| |..| ||.. |   ||  |.|..    || ..|. ||  ..  .|     |..   . || ..   . .| ..   |   |    |.  . .|
TGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKDPDNTWYCKK-----TRDKKKHYKEPCTRKLHEILGVETGGP--GGRRKGEPGHSVED

RMEFISLLSRMLSLDPTQRIRPLSALQSPFI
 . |  |. |||  || |||.|. ||| .|.
YLKFKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase AqueK114.AA S_TKc 69-396 23 1.5e-72 248.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 69-396
Range on HMM: 1-231/231
Sequence Identity: 23% (80 aa)

YDVLDRLGRGTFGQVVRAWKKNTSEIVAIKILKSTPSYAKQGQMEVDVLSKLSRLSPDEGSFVKAYESFQHHGHICIVFELLHI---NLYDYLKQSRFDP
|..|. .|.|.||.| ....|.| .||||||.|      .. . |...|.|      .    || |..||. .|...|.|..     .|.||.|. .  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPLKYIRPIAQQVLCCLEKLASLGLVHADLKPENIMLVDPQRYPFKVKVIDFGSAMSRDKTSPSCYLQSRYYRAPEVILGVNFNE-GIDMWSLGCV
    .|   .| ...|..| || . |.| .| |||||||.| .       .|..|||.|        . .  ...|.||||.    ..   .|.||.||.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LAELYLGWPLFPGASEFDQITYICQTLGPLPHHLMRNITKATRFFNCDPVTSTWSLKSISQYTQETGIQSKESRKYIFRSLLDMNHLPPLAAGIDNREAI
|.|.. | |.||      |.  . . .|                                                                        
LYEMLCGYPPFP------QMQMMFKKIG------------------------------------------------------------------------

LTSVDRMEFISLLSRMLSLDPTQRIRPLSALQ-------SPFI
       |........|  ||..|.    |||        |..
-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK114.AA PRP4 69-297 35 2.5e-50 173.52 In-house 1-231 (320) Show / Hide 
Range on Protein: 69-297
Range on HMM: 1-231/320
Sequence Identity: 35% (82 aa)

YDVLDRLGRGTFGQVVRAW-KKNTSEIVAIKILKSTPSYAKQGQMEVDVLSKLSRL--SPDEGS-FVKAYESFQHHGHICIVFELLHINLYDYLKQ-SRF
| |    | | |. |.|.  . .. | |||||. . ..  | |  |. .| ||.    .... .  |. ...|.|. |.|.||| .  || . ||.  . 
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

DPLPLKYIRPIAQQVLCCLEKLASLGLVHADLKPENIMLVDPQRYPFKVKVIDFGSAMSRDKTSPSCYLQSRYYRAPEVILGVNFNEGIDMWSLGCVLAE
. | || .|  ||| .  |  |  .. .|||.|| ||.    .      | .|||||          ||.||.|||||.|.|...  .||||| || |.|
VGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILVNESKNT---LKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYE

LYLGWPLFPGASEFDQITYICQTLGPLPHHLMRN
|| |  .||| .  . .  .    | .|. ..|.
LYTGKIMFPGKTNNHMLKLFMDYKGKMPNKMIRK
Kinase AqueK114.AA CLK 69-211 33 3.5e-46 136.03 In-house 1-160 (350) Show / Hide 
Range on Protein: 69-211
Range on HMM: 1-160/350
Sequence Identity: 33% (53 aa)

YDVLDRLGRGTFGQVVRAWKKNTS-EIVAIKILKSTPSYAKQGQMEVD-VLSKLSRL-SPDEGSF---VKAYESFQH-HGHICIVFELLHINLYDYLKQS
| ... || |||| ||. |  . .   ||.|| ..   |  . . |.. .. |.    .|.  .    .| ...| . ||||||||||.  ..|| .|  
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

R------FDPLPLKYIRPIAQQVLCCLEKLASLGLVHADLKPENIMLVDP----QRYPFK
.      . |.|.  || .| | .  ...| ...|.| ||||||| .||.     .. ||
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRFTHFDCTFK
Kinase AqueK114.AA Pkinase 69-292 31 6.3e-44 156.39 Pfam 1-236 (293) Show / Hide 
Range on Protein: 69-292
Range on HMM: 1-236/293
Sequence Identity: 31% (76 aa)

YDVLDRLGRGTFGQVVRAWKKNTSEIVAIKILKSTPSYAKQGQM-----EVDVLSKLSRLSPDEGSFVKAYESFQHHGHICIVFELLHI-----NLYDYL
| .. ..|.|.||.| .. .|.|..|||.||.|      .. |      |. .. .|.  .|     |. |..|. ..||..|.|..        |.||.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN--HPN---IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

KQSRFDPL--PLKYIRPIAQQVLCCLEKLASLGLVHADLKPENIMLVDPQRYPFKVKVIDFGSAM---SRDKTSPSCYLQSRYYRAPEVIL-GVNFNEGI
. .|  ..  . . .. .. |.|. || . | | .| |||||||....    . .||..|||.|       .. .. .  ...|.|||||. |      .
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DMWSLGCVLAELYLGWPLFPGA----SEFDQITYICQTLGPLPH
||||.||.|.|...| |.|||.    .  ||.  ||...|| .|
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLH
Kinase AqueK114.AA RCK 145-288 40 1.4e-38 119.79 In-house 77-231 (298) Show / Hide 
Range on Protein: 145-288
Range on HMM: 77-231/298
Sequence Identity: 40% (62 aa)

IVFELLHINLYDYLKQ--SRFDPLPLKY--IRPIAQQVLCCLEKLASLGLVHADLKPENIMLVDPQRY-----PFKVKVIDFGSA-MSRDKTSPSCYLQS
.|||..  ||| ..|    |  .|| .   |. |  |.|  |. . . |  | ||||||||. . | |     .. .|..|||..   |.|     |  .
FVFEYMDMNLYQMMKDFKERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVST

RYYRAPEVILGV-NFNEGIDMWSLGCVLAELYLGWPLFPGASEFDQITYICQTLG
|.|||||..|   . |. .|.|..||. .|||  .|||||.|| |||  ||. .|
RWYRAPECLLRCTYYNSPMDIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMG
Kinase AqueK114.AA GSK 144-288 41 1.5e-32 96.25 In-house 89-236 (328) Show / Hide 
Range on Protein: 144-288
Range on HMM: 89-236/328
Sequence Identity: 41% (62 aa)

CIVFELLHINLYDYLKQ--SRFDPLPLKYIRPIAQQVLCCLEKLASLGLVHADLKPENIMLVDPQRYPFKVKVIDFGSAM--SRDK-TSPSCYLQSRYYR
|.|.| .  .||.....      ..|...|. .. | .. |  | |.| .| |.||.|| ||||.    ..|  |||||    . | ..   |  |||||
CLVMEYMPQTLYQVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNI-LVDPDT--GVLKICDFGSAKQLEPNKNEPNISYICSRYYR

APEVILGV-NFNEGIDMWSLGCVLAELYLGWPLFPGASEFDQITYICQTLG
||| |.|  |..  ||.||.|||.||. .| ||||| |. ||.  |.. ||
APELIFGCTNYTCQIDVWSCGCVMAEMLKGQPLFPGDSSVDQLVEIIKMLG
Kinase AqueK114.AA CLK 212-306 36 1.6e-23 66.76 In-house 186-286 (350) Show / Hide 
Range on Protein: 212-306
Range on HMM: 186-286/350
Sequence Identity: 36% (37 aa)

VKVIDFGSAM-SR-DKTSPSCYLQSRYYRAPEVILGVNFNEGIDMWSLGCVLAELYLGWPLFPGASEFDQITYICQTLG-PLPHHL---MRNITKATRFF
..|||||||  .| |..  |   ..| |||||||||  ...  | || ||.| |||.|  ||.. .. .    .   .| |.| .    .|.    ...|
ICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQKYF

N
.
Y
Kinase AqueK114.AA RCK 69-101 51 4.4e-12 34.35 In-house 1-33 (298) Show / Hide 
Range on Protein: 69-101
Range on HMM: 1-33/298
Sequence Identity: 51% (17 aa)

YDVLDRLGRGTFGQVVRAWKKNTSEIVAIKILK
| ....||.||.| |. | .| | |||||| .|
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK
Kinase AqueK114.AA TyrKc 69-305 21 6.2e-09 -78.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 69-305
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

YDVLDRLGRGTFGQVVRAWKKNTSEIVAIKILKSTPSYAKQGQMEVDVLSKL-------------SRLSPDEGSFVKAYESFQHHGHICIVFELL-HINL
   .. ||.| ||.|...  |   . ||.| ||.     .    |  ...||              . .            |   . ..||.|.  | .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN---------FMYIEPLMIVMEYMPHGDL

YDYLKQSRFDPLPLKYIRPIAQQVLCCLEKLASLGLVHADLKPENIMLVDPQRYPFKVKVIDFGSAMSRDKTSP-------SCYL-----QSR-----YY
 |||. .| . |..|    .. |. |  | |.| ...| ||   |... ...     ||. |||  .||| ..        . |      ...       
KDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFG--LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

RAPEVILGVNFNEGIDMWSLGCVLAELY-LGWPLFPG-----ASEFDQITYICQT-LGPLPHH---------------LMRNITKA-----------TRF
 |||.|    |..  | || | .. |.. .| .  ||      | .. | |. |    | |..               .|.   ..            ..
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

F
|
F
Kinase AqueK114.AA GSK 69-98 36 9.3e-09 22.26 In-house 1-38 (328) Show / Hide 
Range on Protein: 69-98
Range on HMM: 1-38/328
Sequence Identity: 36% (14 aa)

YDVLDRLGRGTFGQVVRAWKK----NTSEI----VAIK
|.  .. |.|.|| |..|  .    .|.||    ||||
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIK
Kinase AqueK114.AA GSK 372-396 44 2e-06 14.87 In-house 304-328 (328) Show / Hide 
Range on Protein: 372-396
Range on HMM: 304-328/328
Sequence Identity: 44% (11 aa)

LLSRMLSLDPTQRIRPLSALQSPFI
|.|..|  ||..|..|| |...|| 
LISKCLVYDPKKRLSPLEACAHPFF
Kinase AqueK114.AA PRP4 372-396 52 3e-06 18.88 In-house 296-320 (320) Show / Hide 
Range on Protein: 372-396
Range on HMM: 296-320/320
Sequence Identity: 52% (13 aa)

LLSRMLSLDPTQRIRPLSALQSPFI
|| ..| |||  || .  ||. |||
LLDKCLMLDPKKRITCNEALKHPFI
Kinase AqueK114.AA CLK 368-396 41 5e-06 13.35 In-house 322-350 (350) Show / Hide 
Range on Protein: 368-396
Range on HMM: 322-350/350
Sequence Identity: 41% (12 aa)

EFISLLSRMLSLDPTQRIRPLSALQSPFI
... |...||  ||..||    ||| || 
QLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase AqueK114.AA YAK 369-396 42 2.4e-05 13.72 In-house 320-347 (347) Show / Hide 
Range on Protein: 369-396
Range on HMM: 320-347/347
Sequence Identity: 42% (12 aa)

FISLLSRMLSLDPTQRIRPLSALQSPFI
|| ..  .| |.|  |  |  | | |||
FIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase AqueK114.AA Pkinase_Tyr 69-101 37 4e-05 17.99 Pfam 1-37 (270) Show / Hide 
Range on Protein: 69-101
Range on HMM: 1-37/270
Sequence Identity: 37% (14 aa)

YDVLDRLGRGTFGQVVRAWKK----NTSEIVAIKILK
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ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK
Kinase AqueK114.AA Pkinase 368-396 27 4.6e-05 18.99 Pfam 265-293 (293) Show / Hide 
Range on Protein: 368-396
Range on HMM: 265-293/293
Sequence Identity: 27% (8 aa)

EFISLLSRMLSLDPTQRIRPLSALQSPFI
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ECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK114.AA RCK 368-396 41 0.000321 8.97 In-house 270-298 (298) Show / Hide 
Range on Protein: 368-396
Range on HMM: 270-298/298
Sequence Identity: 41% (12 aa)

EFISLLSRMLSLDPTQRIRPLSALQSPFI
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DCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase AqueK114.AA DYRK2 369-396 39 0.001381 7.16 In-house 291-318 (318) Show / Hide 
Range on Protein: 369-396
Range on HMM: 291-318/318
Sequence Identity: 39% (11 aa)

FISLLSRMLSLDPTQRIRPLSALQSPFI
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FIDFIKRCFEWDPSERMTPSQALKHPWI