Gene AqueK122 (A.queenslandica)

AqueK122

Species: A.queenslandica
Alias: AqueK122
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK7

Sequence

Name Sequence Type Origin Length Description Download
AqueK122.AA Protein None 179 None Fasta, JSON
AqueK122.kin_dom Protein Kinase Domain None 57 None Fasta, JSON

Protein domain

Protein domains of AqueK122.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK122.AA ERK7 3-60 67 2.1e-28 94.0 In-house 84-140 (292) Show / Hide 
Range on Protein: 3-60
Range on HMM: 84-140/292
Sequence Identity: 67% (39 aa)

NTDLHAVIKSKIPVL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIK
.|||||||. |  .|  .| |||| || | .||.||||||||||||||||..|||..|
ETDLHAVIR-KGNILKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVK
Kinase AqueK122.AA MAPK 4-60 61 1.2e-26 89.03 In-house 100-157 (328) Show / Hide 
Range on Protein: 4-60
Range on HMM: 100-157/328
Sequence Identity: 61% (36 aa)

TDLHAVIKSKIPVL*SVHMQYIMSQLCRV--LKYIHSGNVIHRDLKPSNILINSECFIK
||||..|||    |   |.||.| |..|   ||||||.|||||||||||||.|..|  |
TDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLK
Kinase AqueK122.AA CMGC 1-57 32 3.3e-20 62.26 In-house 136-221 (513) Show / Hide 
Range on Protein: 1-57
Range on HMM: 136-221/513
Sequence Identity: 32% (28 aa)

LINTDLHAVIKS--------KIPVL*SVH------------MQYIM------SQLCRVLK--YIHSGN--VIHRDLKPSNILINSEC
.. .||. .||.        .   |   |             .|.|       |..| ||  |.|| .  .|||||||.|||||..|
YMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNC
Kinase AqueK122.AA MAPK-Unclassified 1-60 47 5.9e-20 68.45 In-house 87-149 (575) Show / Hide 
Range on Protein: 1-60
Range on HMM: 87-149/575
Sequence Identity: 47% (30 aa)

LINT---DLHAVIKSKIPVL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIK
.  |   ||| .||| .  .   | ||.. |. | |||.|| ..|||||||||.|||  | ..
YMQTSLFDLHQIIKSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVR
Kinase AqueK122.AA ERK 1-57 61 2.1e-19 69.01 In-house 90-145 (307) Show / Hide 
Range on Protein: 1-57
Range on HMM: 90-145/307
Sequence Identity: 61% (35 aa)

LINTDLHAVIKSKIPVL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSEC
|. |||| .|.|.   |   | || | |. . |||||| |||||||||||||.|| |
LMETDLHQIINSQQ-ELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNC
Kinase AqueK122.AA p38 1-57 45 6.5e-17 54.07 In-house 89-143 (289) Show / Hide 
Range on Protein: 1-57
Range on HMM: 89-143/289
Sequence Identity: 45% (26 aa)

LINTDLHAVIKSKIPVL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSEC
.  .||. ..|..   |   | |..  |. | |||||| ..|||||||||| .| .|
FMGADLNNIMKCQR--LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDC
Kinase AqueK122.AA ERK5 1-60 50 1.6e-16 56.98 In-house 85-143 (295) Show / Hide 
Range on Protein: 1-60
Range on HMM: 85-143/295
Sequence Identity: 50% (30 aa)

LINTDLHAVIKSKIPVL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIK
|.  ||| .| |  | .   |. | . |. | |||.|| .||||||||||.|.|  | .|
LMESDLHQIIHSNQP-FTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELK
Kinase AqueK122.AA ERK3 21-56 66 2.5e-16 48.69 In-house 111-146 (300) Show / Hide 
Range on Protein: 21-56
Range on HMM: 111-146/300
Sequence Identity: 66% (24 aa)

HMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSE
| .  | || | |||||| || |||||| ||.|| |
HARLFMYQLLRGLKYIHSANVLHRDLKPANIFINTE
Kinase AqueK122.AA ERK1 1-60 50 1.2e-14 51.29 In-house 83-140 (289) Show / Hide 
Range on Protein: 1-60
Range on HMM: 83-140/289
Sequence Identity: 50% (30 aa)

LINTDLHAVIKSKIPVL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIK
|. |||  ..|..   |   |. | . |. | |||||| ||.||||||||.|.|  | .|
LMETDLYKLLKTQ--HLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLK
Kinase AqueK122.AA nmo 1-60 46 1.8e-14 40.3 In-house 84-142 (292) Show / Hide 
Range on Protein: 1-60
Range on HMM: 84-142/292
Sequence Identity: 46% (28 aa)

LINTDLHAVIKSKIPVL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIK
|.  ||| .| |  . | | |..  . |. | |||.|| |..|||.|| |.|.||.| .|
LMQSDLHKIIVSPQH-LSSDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLK
Kinase AqueK122.AA Pkinase 3-60 33 8e-14 49.95 Pfam 84-152 (293) Show / Hide 
Range on Protein: 3-60
Range on HMM: 84-152/293
Sequence Identity: 33% (23 aa)

NT----DLHAVIK--SKIPV-L*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFI----K
..    ||...|.  .. .. .   . . .| |..| |.|.|| ..|||||||.||||.... |    |
GGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVK
Kinase AqueK122.AA ERK7 134-179 41 1.4e-14 45.96 In-house 204-249 (292) Show / Hide 
Range on Protein: 134-179
Range on HMM: 204-249/292
Sequence Identity: 41% (19 aa)

RPLYPGSSTINQLNRIMSTLPPPSRQDVESIKSPYAKAILDQIIHK
.|..||.||.||...|. |.| |...|.|.|.| ||  .|.|....
KPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQ
Kinase AqueK122.AA MAPK 134-173 36 8.9e-10 29.76 In-house 232-272 (328) Show / Hide 
Range on Protein: 134-173
Range on HMM: 232-272/328
Sequence Identity: 36% (15 aa)

RPLYPGSSTINQLNRIMSTLPPPSRQDVESIK-SPYAKAIL
.|| ||...|.|.|.||..|. ||..... |. |. |.  .
KPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYI
Kinase AqueK122.AA CMGC 134-168 22 6.7e-05 11.02 In-house 340-401 (513) Show / Hide 
Range on Protein: 134-168
Range on HMM: 340-401/513
Sequence Identity: 22% (14 aa)

RPLYP-----------GSSTINQLNRIMSTLPPP----------------SRQDVESIKSPY
.|| |           |.|.|.||..|. .| .|                .... . || |.
KPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPW
Kinase AqueK122.AA ERK1 134-179 36 0.000102 13.63 In-house 201-246 (289) Show / Hide 
Range on Protein: 134-179
Range on HMM: 201-246/289
Sequence Identity: 36% (17 aa)

RPLYPGSSTINQLNRIMSTLPPPSRQDVESIKSPYAKAILDQIIHK
||..||   . ||| |.. |  ||..|.. |    |.. |  . ||
RPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHK
Kinase AqueK122.AA p38 134-173 35 0.000758 8.71 In-house 201-240 (289) Show / Hide 
Range on Protein: 134-173
Range on HMM: 201-240/289
Sequence Identity: 35% (14 aa)

RPLYPGSSTINQLNRIMSTLPPPSRQDVESIKSPYAKAIL
|.|.||.  |.||.|||. .  |..  .. |.|  |.. .
RTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYI
Kinase AqueK122.AA ERK 134-170 36 0.001496 9.32 In-house 214-251 (307) Show / Hide 
Range on Protein: 134-170
Range on HMM: 214-251/307
Sequence Identity: 36% (14 aa)

RPLYPGSSTINQLNRIMSTLPPP-SRQDVESIKSPYAK
.|| || ....|.||| ...  | | .|.. |.|. |.
KPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAW
Kinase AqueK122.AA Pkinase 134-179 17 7.239718 0.61 Pfam 209-276 (293) Show / Hide 
Range on Protein: 134-179
Range on HMM: 209-276/293
Sequence Identity: 17% (12 aa)

RPLYPGS----STINQLNRIMSTLPPPSRQDVESIKS-------------------PYAKAILDQIIHK
||..||.    . ..|. .|  ...|| . | .   |                   . .| ... ...|
RPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK