Gene AqueK123 (A.queenslandica)

AqueK123

Species: A.queenslandica
Alias: AqueK123
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK7

Sequence

Name Sequence Type Origin Length Description Download
AqueK123.AA Protein None 484 None Fasta, JSON
AqueK123.kin_dom Protein Kinase Domain None 219 None Fasta, JSON

Protein domain

Protein domains of AqueK123.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK123.AA ERK7 3-58 70 5.8e-31 102.9 In-house 84-140 (292) Show / Hide 
Range on Protein: 3-58
Range on HMM: 84-140/292
Sequence Identity: 70% (40 aa)

ETDLHAVIK-SKIL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIK
||||||||.  .||  .| |||| || | .||.||||||||||||||||..|||..|
ETDLHAVIRKGNILKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVK
Kinase AqueK123.AA MAPK 1-58 62 2.9e-28 94.67 In-house 97-157 (328) Show / Hide 
Range on Protein: 1-58
Range on HMM: 97-157/328
Sequence Identity: 62% (38 aa)

LIETDLHAVIKSKI-L*SVHMQYIMSQLCRV--LKYIHSGNVIHRDLKPSNILINSECFIK
| |||||..|||   |   |.||.| |..|   ||||||.|||||||||||||.|..|  |
LMETDLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLK
Kinase AqueK123.AA ERK 1-55 64 2.8e-22 79.87 In-house 90-145 (307) Show / Hide 
Range on Protein: 1-55
Range on HMM: 90-145/307
Sequence Identity: 64% (36 aa)

LIETDLHAVIKSK-IL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSEC
|.||||| .|.|.  |   | || | |. . |||||| |||||||||||||.|| |
LMETDLHQIINSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNC
Kinase AqueK123.AA CMGC 1-55 32 2.6e-21 65.95 In-house 136-221 (513) Show / Hide 
Range on Protein: 1-55
Range on HMM: 136-221/513
Sequence Identity: 32% (28 aa)

LIETDLHAVIKS----------KIL*SVH------------MQYIM------SQLCRVLK--YIHSGN--VIHRDLKPSNILINSEC
....||. .||.          . |   |             .|.|       |..| ||  |.|| .  .|||||||.|||||..|
YMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNC
Kinase AqueK123.AA MAPK-Unclassified 1-58 47 8.3e-21 71.58 In-house 87-149 (575) Show / Hide 
Range on Protein: 1-58
Range on HMM: 87-149/575
Sequence Identity: 47% (30 aa)

LIET---DLHAVIKSKI--L*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIK
. .|   ||| .||| .  .   | ||.. |. | |||.|| ..|||||||||.|||  | ..
YMQTSLFDLHQIIKSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVR
Kinase AqueK123.AA ERK3 1-54 55 2e-19 58.84 In-house 93-146 (300) Show / Hide 
Range on Protein: 1-54
Range on HMM: 93-146/300
Sequence Identity: 55% (30 aa)

LIETDLHAVIKSKIL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSE
..||||  |.    |   | .  | || | |||||| || |||||| ||.|| |
YMETDLACVMEQQRLSEEHARLFMYQLLRGLKYIHSANVLHRDLKPANIFINTE
Kinase AqueK123.AA p38 1-55 47 1.7e-18 59.54 In-house 89-143 (289) Show / Hide 
Range on Protein: 1-55
Range on HMM: 89-143/289
Sequence Identity: 47% (26 aa)

LIETDLHAVIKSKIL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSEC
. ..||. ..|.. |   | |..  |. | |||||| ..|||||||||| .| .|
FMGADLNNIMKCQRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDC
Kinase AqueK123.AA ERK1 1-58 53 1.7e-17 62.12 In-house 83-140 (289) Show / Hide 
Range on Protein: 1-58
Range on HMM: 83-140/289
Sequence Identity: 53% (31 aa)

LIETDLHAVIKSKIL*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIK
|.||||  ..|.. |   |. | . |. | |||||| ||.||||||||.|.|  | .|
LMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLK
Kinase AqueK123.AA ERK5 1-58 50 2.5e-16 56.19 In-house 85-143 (295) Show / Hide 
Range on Protein: 1-58
Range on HMM: 85-143/295
Sequence Identity: 50% (30 aa)

LIETDLHAVIKSKIL*SV-HMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIK
|.| ||| .| |    .. |. | . |. | |||.|| .||||||||||.|.|  | .|
LMESDLHQIIHSNQPFTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELK
Kinase AqueK123.AA Pkinase 5-58 36 2.2e-14 51.94 Pfam 90-152 (293) Show / Hide 
Range on Protein: 5-58
Range on HMM: 90-152/293
Sequence Identity: 36% (23 aa)

DLHAVIK---SKIL--*SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFI----K
||...|.   .. .     . . .| |..| |.|.|| ..|||||||.||||.... |    |
DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVK
Kinase AqueK123.AA CDK4 21-58 47 3.9e-11 34.25 In-house 113-150 (290) Show / Hide 
Range on Protein: 21-58
Range on HMM: 113-150/290
Sequence Identity: 47% (18 aa)

QYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIK
. .| || | . . ||  .||||||| |||..|.  .|
KHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVK
Kinase AqueK123.AA ERK7 158-220 46 1.2e-20 67.06 In-house 230-292 (292) Show / Hide 
Range on Protein: 158-220
Range on HMM: 230-292/292
Sequence Identity: 46% (29 aa)

DVQSIKSPYAKAILDQIIHKRHKYLTDILPQADDISLDLLNKLLNFNRNKRLTAENCLEHPYL
|...|.| ||  .|.|......| | ...||. |  .||| .|| || .||||||..|.||| 
DIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase AqueK123.AA MAPK 158-220 29 1.8e-14 46.24 In-house 258-328 (328) Show / Hide 
Range on Protein: 158-220
Range on HMM: 258-328/328
Sequence Identity: 29% (21 aa)

DVQSIK-SPYAKAILDQI---IHKRHKYLTDILPQ----ADDISLDLLNKLLNFNRNKRLTAENCLEHPYL
..| |. |. |.  . .     ..  | .....|     |..  .||| |.| |. .||.|.| .|.|||.
FIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase AqueK123.AA ERK 184-220 48 3.7e-13 45.53 In-house 269-307 (307) Show / Hide 
Range on Protein: 184-220
Range on HMM: 269-307/307
Sequence Identity: 48% (19 aa)

DILPQAD--DISLDLLNKLLNFNRNKRLTAENCLEHPYL
.| | |.     .||| |.| |. .||.|.| ||||||.
NIFPNANCNPQAIDLLEKMLVFDPDKRITVEECLEHPYF
Kinase AqueK123.AA CDK4 177-220 36 4.2e-13 41.1 In-house 247-290 (290) Show / Hide 
Range on Protein: 177-220
Range on HMM: 247-290/290
Sequence Identity: 36% (16 aa)

KRHKYLTDILPQADDISLDLLNKLLNFNRNKRLTAENCLEHPYL
.. . . |. |. .   .|||.| | .|  ||..|. ||.|||.
RHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF
Kinase AqueK123.AA ERK3 179-220 42 2e-12 35.9 In-house 259-300 (300) Show / Hide 
Range on Protein: 179-220
Range on HMM: 259-300/300
Sequence Identity: 42% (18 aa)

HKYLTDILPQADDISLDLLNKLLNFNRNKRLTAENCLEHPYL
|. |. .|.. |   ||.| ..| |.   |||||  |.|||.
HHPLKQLLCNIDCHALDFLEQMLTFDPMDRLTAEMALQHPYM
Kinase AqueK123.AA ERK1 158-220 41 2.7e-12 42.41 In-house 227-289 (289) Show / Hide 
Range on Protein: 158-220
Range on HMM: 227-289/289
Sequence Identity: 41% (26 aa)

DVQSIKSPYAKAILDQIIHKRHKYLTDILPQADDISLDLLNKLLNFNRNKRLTAENCLEHPYL
|.. |    |.. |  . || .  .  . |.||   ||||.|.| || .||.| |. | ||||
DLNCIINEKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase AqueK123.AA p38 159-220 29 3.6e-12 37.61 In-house 228-289 (289) Show / Hide 
Range on Protein: 159-220
Range on HMM: 228-289/289
Sequence Identity: 29% (18 aa)

VQSIKSPYAKAILDQIIHKRHKYLTDILPQADDISLDLLNKLLNFNRNKRLTAENCLEHPYL
.| |.|  |.. .  .     . .......|.   .||| |.|     ||.|||  ..|||.
WQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase AqueK123.AA CMGC 158-220 18 9.2e-12 33.99 In-house 413-513 (513) Show / Hide 
Range on Protein: 158-220
Range on HMM: 413-513/513
Sequence Identity: 18% (19 aa)

DVQSIKSPYAKAILDQ---IIHKRHKYLTDILPQ-----------------------------------ADDISLDLLNKLLNFNRNKRLTAENCLEHPY
......|. |.  . .      .. | .... |                                    .|.  .|||.|.| .. .||.||| .|.|||
TMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPY

L
.
F
Kinase AqueK123.AA ERK5 159-220 26 6.6e-09 28.66 In-house 233-295 (295) Show / Hide 
Range on Protein: 159-220
Range on HMM: 233-295/295
Sequence Identity: 26% (17 aa)

VQSIKSPYAKAILDQ-IIHKRHKYLTDILPQADDISLDLLNKLLNFNRNKRLTAENCLEHPYL
.|.. .   .. . . .  .. | .  . |.||  .|||| ..| |   .|.|.   | ||.|
IQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase AqueK123.AA MAPK-Unclassified 194-220 51 1.5e-08 26.51 In-house 549-575 (575) Show / Hide 
Range on Protein: 194-220
Range on HMM: 549-575/575
Sequence Identity: 51% (14 aa)

LDLLNKLLNFNRNKRLTAENCLEHPYL
.|...|.| || .|| ||.  ||||| 
IDFVQKMLQFNPWKRITADQALEHPYF
Kinase AqueK123.AA Pkinase 194-220 37 5.6e-08 29.3 Pfam 267-293 (293) Show / Hide 
Range on Protein: 194-220
Range on HMM: 267-293/293
Sequence Identity: 37% (10 aa)

LDLLNKLLNFNRNKRLTAENCLEHPYL
.|.....|... .||.||| .|.||..
KDFIKWCLCKDPKKRPTAEQILQHPWF