Gene AqueK126 (A.queenslandica)

AqueK126

Species: A.queenslandica
Alias: AqueK126
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK7

Sequence

Name Sequence Type Origin Length Description Download
AqueK126.AA Protein None 581 None Fasta, JSON
AqueK126.kin_dom Protein Kinase Domain None 301 None Fasta, JSON

Protein domain

Protein domains of AqueK126.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK126.AA ERK7 13-313 60 1.3e-186 626.27 In-house 1-292 (292) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-292/292
Sequence Identity: 60% (184 aa)

YDIKRRIGKGAYGIVWKSVDRRTGEIVALKKIFDAFANSTDAQRTFREILFLQAFSNHPNVIQLINVIRSSTDKDIYLVFEFMDTDLHAVIK-SKILQSV
|.|..|.|||||||||| .|.||...|||||||||| |.||||||||||.|||.| .|||.|.|||||| . |.|||||||||.|||||||.  .||. .
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRKGNILKDI

HMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIKLADFGLARSLASISNEGSKGAGGDGVSDFNPAMTDYVATRWYRSPEILLGSRRYTRGVDM
| |||| || | .||.||||||||||||||||..|||..|..|||||||.|.. .           .. ||..|.||||||||.|||||||.|||.||||
HKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEY----------DEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDM

WSLGCILAEMIASKPLYPGSSTINQLDRIMSTLPPPSRQDVESIKSPYAKAILDQIIHKRHKYLTDILPQADDISLDLLNKLLNFNPNKRLTAENCLEHP
||.||||.||.  ||..||.||.||...|. |.| |...|.|.|.| ||  .|.|......| | ...||. |  .||| .|| |||.||||||..|.||
WSIGCILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHP

YL
| 
YV
Kinase AqueK126.AA MAPK 13-313 42 2.9e-154 518.78 In-house 1-328 (328) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-328/328
Sequence Identity: 42% (141 aa)

YDIKRRIGKGAYGIVWKSVDRR------TGEIVALKKIFDAFANSTDAQRTFREILFLQAFSNHPNVIQLINVIRSS-----TD----KDIYLVFEFMDT
|.| ..||.||||.|.. .|.|      .|..||.|||...| | |...||.||| .|. | .|.|.| |..... .      .    .|||.|.|.|.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLHAVIKSKI-LQSVHMQYIMSQLCRV--LKYIHSGNVIHRDLKPSNILINSECFIKLADFGLARSLASISNEGSKGAGGDGVSDFNP--AMTDYVATRW
|||..|||   |   |.||.| |..|   ||||||.|||||||||||||.|..|  |..|||||||... ...  . . .  .. |     ||.||||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDP--HC-F-QKMHMTEYVATRW

YRSPEILLG--SRRYTRGVDMWSLGCILAEMIA-SKPLYPGSSTINQLDRIMSTLPPPSRQDVESIK-SPYAKAILDQI---IHKRHKYLTDILPQ----
||.|||.|.  ...|| .|||||.|||.|||.   ||| ||...|.|. .||..|. ||..... |. |. |.  . .     ..  | .....|     
YRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFN

ADDISLDLLNKLLNFNPNKRLTAENCLEHPYL
|..  .||| |.| |.|.||.|.| .|.|||.
ANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase AqueK126.AA CMGC 13-313 25 9.60000000001e-129 425.54 In-house 1-513 (513) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-513/513
Sequence Identity: 25% (132 aa)

YDIKRRIGKGAYGIVWKSVD--------------RRTGEIVALKKIFDAFANSTDAQ----------RTFREILFLQAFS----------------NHPN
|.| ..||.|.||.|.| .|              ..|.||||.|||. .| . ..|.          |..||| .|. ..                .|.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VIQLINVIRSST---------------DKDIYLVFEFMDTDLHAVIKS----------KILQSVH------------MQYIM------SQLCRVLK--YI
...|.......                ....|||||.||.||. .||.          . |   |             .|.|       |..| ||  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSGN--VIHRDLKPSNILINSECF--------------------IKLADFGLARSLASISNEGSKGAGGDGVSDF---------NPAMTDYVATRWYRSP
|| .  .|||||||.|||||..|                     .|..||||||.. . |..  .  .      |         | ..|.||.|||||.|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQS----FKNVNKDDKPNRPYTHYVVTRWYRAP

EILLGSRRYT---------RGVDMWSLGCILAEMIAS--------KPLYP-----------GSSTINQLDRIMSTLPPP----------------SRQDV
|||||...||          ..||||.|||.|||.          ||| |           |.|.|.||..|. .| .|                .... 
EILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWP

ESIKSPYAKA------------ILDQ-----------IIHKRHKYLTDILPQ-----------------------------------ADDISLDLLNKLL
. || |. .             ...               .. | .... |                                    .|.  .|||.|.|
NMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKML

NFNPNKRLTAENCLEHPYL
 ..|.||.||| .|.|||.
QYDPDKRITAEQALQHPYF
Kinase AqueK126.AA ERK 13-313 43 8.60000000001e-124 417.56 In-house 1-307 (307) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-307/307
Sequence Identity: 43% (138 aa)

YDIKRRIGKGAYGIVWKSVDRR-----TGEIVALKKIFDAFANSTDAQRTFREILFLQAFSNHPNVIQLINVIRSS---TDKDIYLVFEFMDTDLHAVIK
| |  .||.||||.| ...|       ||..|| |||..|| .  .. || ||| .|  |  |.|.| |.......     .|||.|.|.|.|||| .|.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

SK-ILQSVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIKLADFGLARSLASISNEGSKGAGGDGVSDFNPAMTDYVATRWYRSPEILLGSR
|.  |   | || | |. . |||||| |||||||||||||.|| |  | .|||||| ... ..|...          .. ||.||||||||.|||.|  .
SQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHE--------CNQNFMTEYVATRWYRAPEIMLSWQ

RYTRGVDMWSLGCILAEMIASKPLYPGSSTINQLDRIMSTLPPP-SRQDVESIKSPYAKAILDQIIH--KRHKYLTDILPQAD--DISLDLLNKLLNFNP
 ||. .|.|| |||.|||.. ||| || ....|..|| ...  | | .|.. |.|. |.  . .  .  .  | . .| | |.     .||| |.| |.|
KYTKAMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDP

NKRLTAENCLEHPYL
.||.|.| ||||||.
DKRITVEECLEHPYF
Kinase AqueK126.AA p38 13-313 39 4.1e-101 342.24 In-house 1-289 (289) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-289/289
Sequence Identity: 39% (121 aa)

YDIKRRIGKGAYGIVWKSVDRRTGEI---VALKKIFDAFANSTDAQRTFREILFLQAFSNHPNVIQLINVIRS-----STDKDIYLVFEFMDTDLHAVIK
|   . .|.|||| | | .|||||.    || ||..  |    .| ||.||.  |.   .| |||.|..|        .  .|.|.| .||..||. ..|
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHM-RHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMK

SKILQSVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIKLADFGLARSLASISNEGSKGAGGDGVSDFNPAMTDYVATRWYRSPEILLGSRR
.. |   | |..  |. | |||||| ..|||||||||| .| .| ..  ||||||                        ||.||||||||.|||.|   .
CQRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR-------------------HCDDEMTGYVATRWYRAPEIMLNWMH

YTRGVDMWSLGCILAEMIASKPLYPGSSTINQLDRIMSTLPPPSRQDVESIKSPYAKAILDQIIHKRHKYLTDILPQADDISLDLLNKLLNFNPNKRLTA
||  ||.||.|||.||.|  ..|.||.  |.|| |||. .  |..  .. |.|  |.. .  .     . .......|.   .||| |.|   | ||.||
YTQTVDIWSVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITA

ENCLEHPYL
|  ..|||.
EEAMQHPYF
Kinase AqueK126.AA CDK 13-313 34 3.8e-100 321.13 In-house 1-284 (284) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-284/284
Sequence Identity: 34% (115 aa)

YDIKRRIGKGAYGIVWKSVDRRTG-----EIVALKKIF----------DAFANSTDAQRTFREILFLQAFSNHPNVIQLINVIRSS-TD--------KDI
|..  .|| |.||.| |  |..||     .|||||||           . |  .     . |||  |.    |||...|. |. .. .|        . .
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPIT-----AIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKL

YLVFEFMDTDLHAVIKSKILQSVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECF-----IKLADFGLARSLASISNEGSKGAGGDGVSDFNPA
|.|||.||.||  ...         . .| || | | |.|| ...||||||.|||||.        .|.|||||||   . ..         .  . | .
YMVFEYMDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQ---------MS-EPNRT

MTDYVATRWYRSPEILLGSRRYT--RGVDMWSLGCILAEMIA---SKPLYPGSSTINQLDRIMSTLPPPSRQDVESIKS-PYAKAILDQIIHKRHKYLTD
.|  | |.|||.||.||||..|.   ..||||.|||.|||.     ||| ||.| |.||..|  ..  |. ..  .... |.                  
YTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-----------------

ILPQADDISLDLLNKLLNFNPNKRLTAENCLEHPYL
          |||||.| ..|.||..|| .|.|||.
----------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase AqueK126.AA S_TKc 13-313 29 1.9e-99 337.6 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-231/231
Sequence Identity: 29% (93 aa)

YDIKRRIGKGAYGIVWKSVDRRTGEIVALKKIFDAFANSTDAQRTFREILFLQAFSNHPNVIQLINVIRSSTDKDIYLVFEFMDT---DLHAVIKSKI--
|.| | |||||.| |.| ....||.|||.|.|          ... |||  |.   .|||...|. |...   ...|.|.|..|.   ||. .||..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LQSVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIKLADFGLARSLASISNEGSKGAGGDGVSDFNPAMTDYVATRWYRSPEILLGS
     .   | ...| |.|. |.|.|| ..|||||||.|||...   ||..|||||| |                       | .. |.||..||.|   
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------------------TTFCGTPWYMAPEVL---

RRYTR-GVDMWSLGCILAEMIASKPLYPGSSTINQLDRIMSTLPPPSRQDVESIKSPYAKAILDQIIHKRHKYLTDILPQADDISLDLLNKLLNFNPNKR
  |..  .|.||.||||.||.. .|..|       ...|.                                         ..  .|...|.|...|.||
-GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------------------------------------SPEAKDFIRKCLQKDPEKR

LTAENCLE-------HPYL
.||  .|.       ||..
PTA-EALQDEWDIKCHPWF
Kinase AqueK126.AA ERK1 13-313 44 2.3e-95 323.1 In-house 1-289 (289) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-289/289
Sequence Identity: 44% (134 aa)

YDIKRRIGKGAYGIVWKSVDRRTGEIVALKKIFDAFANSTDAQRTFREILFLQAFSNHPNVIQLINVIRSST---DKDIYLVFEFMDTDLHAVIKSKILQ
|   . ||.||||.|   .|..... ||.|||   |   |  ||| |||  |. | .| |.|.. ..||..|    .|.|.| . |.|||  ..|.. | 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKI-SPFEHQTYCQRTLREIKILTRF-KHENIINIQDIIRADTIEQMRDVYIVQCLMETDLYKLLKTQHLS

SVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIKLADFGLARSLASISNEGSKGAGGDGVSDFNPAMTDYVATRWYRSPEILLGSRRYTRGV
  |. | . |. | |||||| ||.||||||||.|.|  | .|. |||||| .|            |   |    .|.|||||||| |||.| |. ||. .
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-IA------------DPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSI

DMWSLGCILAEMIASKPLYPGSSTINQLDRIMSTLPPPSRQDVESIKSPYAKAILDQIIHKRHKYLTDILPQADDISLDLLNKLLNFNPNKRLTAENCLE
|.|| |||||||.. .|..||   . ||  |.. |  ||..|.. |    |.. |  . || .  .  . |.||   ||||.|.| |||.||.| |. | 
DIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALA

HPYL
||||
HPYL
Kinase AqueK126.AA Pkinase 13-313 30 1.6e-93 321.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-293/293
Sequence Identity: 30% (98 aa)

YDIKRRIGKGAYGIVWKSVDRRTGEIVALKKIFDAFANSTDAQRTFR--EILFLQAFSNHPNVIQLINVIRSSTDKDIYLVFEFMDT-----DLHAVIK-
| |.|.||.|..| |.| ... ||.|||.|.|    ..|   |. .|  ||  .. . ||||...|. . ..  ...||.|.|...      ||...|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

--SKIL--QSVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFI----KLADFGLARSLASISNEGSKGAGGDGVSDFNPAMTDYVATRWYRSP
  .. .  .  . . .| |..| |.|.|| ..|||||||.||||.... |    |..|||||. .                   |. ||... |.||..|
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---------------Y-NNS-MTTFCGTPWYMAP

EILLGSRRYTRGVDMWSLGCILAEMIASKPLYPGS----STINQLDRIMSTLP-PPSRQDVESIKSPYAKAILDQIIHKRHKYLTDILPQADDISLDLLN
|...|.. |.. |||||.||||.||.  .|..||.    . ..|. .|  ... |....  ...  .| . . .   |   . ..   . ...  .|...
EVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---F-HWTF-HNWSEECKDFIK

KLLNFNPNKRLTAENCLEHPYL
..|...|.||.||| .|.||..
WCLCKDPKKRPTAEQILQHPWF
Kinase AqueK126.AA ERK5 13-313 40 4.4e-93 315.56 In-house 1-295 (295) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-295/295
Sequence Identity: 40% (124 aa)

YDIKRRIGKGAYGIVWKSVDRRTGEIVALKKIFDAFANSTDAQRTFREILFLQAFSNHPNVIQLINVIRS----STDKDIYLVFEFMDTDLHAVIKSKIL
|.|  .|| ||||.|   . |..|. ||.|||  ||   | |.|||||.  |. |  | |.| . ....     |  ||.| ||. |. ||| .| |   
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHF-RHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQP

QSV-HMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIKLADFGLARSLASISNEGSKGAGGDGVSDFNPAMTDYVATRWYRSPEILLGSRRYTR
 .. |. | . |. | |||.|| .||||||||||.|.|  | .|. |||.|| |. .| .  .         |   ||.|||||||| ||... |  || 
FTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQ--------MF---MTEYVATRWYRAPELMFSSHDYTQ

GVDMWSLGCILAEMIASKPLYPGSSTINQLDRIMSTLPPPSRQDVESIKSPYAKAILDQ-IIHKRHKYLTDILPQADDISLDLLNKLLNFNPNKRLTAEN
 .|.|| |||. |||| . ..||   |.||. ||  |  |. . .... .   .. . . .  .. | .  . |.||  .|||| ..| | | .|.|.  
AIDVWSVGCIFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNK

CLEHPYL
 | ||.|
ALQHPFL
Kinase AqueK126.AA CDC2 13-240 37 1.2e-75 231.79 In-house 1-221 (301) Show / Hide 
Range on Protein: 13-240
Range on HMM: 1-221/301
Sequence Identity: 37% (90 aa)

YDIKRRIGKGAYGIVWKSVDRRTGEIVALKKIFDAFANSTDA----QRTFREILFLQAFSNHPNVIQLINVIRSSTDKDIYLVFEFMDTDLHAVIK----
|   ..||.| ||.| |  |..|..|||||||     . ..     . . |||  |..  .|||...|  || .   . .|.|||..| ||    .    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKI--RLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIP

S-KILQSVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIKLADFGLARSLASISNEGSKGAGGDGVSDFNPAMTDYVATRWYRSPEILLGSR
. | ...   . .| |... . . |.  ..||||||.||||...  ||.|||||||     ...   .                | |.|||.||||||..
KNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTE--------------HEVVTLWYRAPEILLGCK

RYTRGVDMWSLGCILAEM---IASKPLYPGSSTINQLDRI
||. .|||||.|||.|||   .  ||| .| | | || .|
RYSTPVDMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKI
Kinase AqueK126.AA MAPK-Unclassified 13-160 42 5e-56 192.46 In-house 1-158 (575) Show / Hide 
Range on Protein: 13-160
Range on HMM: 1-158/575
Sequence Identity: 42% (67 aa)

YDIKRRIGKGAYGIVWKSVDRRT-GEIVALKKIFDAFANSTDAQRTFREILFLQAFSNHPNVIQLINVIRSSTDKD-----IYLVFEFMDT---DLHAVI
|. .  || ||||.| . .| .. .  || ||.  .|.| ||. |. |||  |    ||||.||. ....   ..      ||.| ..| |   ||| .|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYL-NHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQII

KSKI--LQSVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIKLADFGLARS
|| .  .   | ||.. |. | |||.|| ..|||||||||.|||  | .. .|||..||
KSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRS
Kinase AqueK126.AA MAPK-Unclassified 184-313 30 8.2e-38 131.94 In-house 405-575 (575) Show / Hide 
Range on Protein: 184-313
Range on HMM: 405-575/575
Sequence Identity: 30% (53 aa)

MTDYVATRWYRSPEILLGSRRYTRGVDMWSLGCILAEMIAS-----------KPLYPGSS--------------------TINQLDRIMSTLPPPSRQDV
|| ||.||||| |||.| .  |.  ||.||.|||.|||.             .|| ||..                     . |.  | . |  |  .| 
MTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDC

ESIKSPYAKAILDQIIHKRHKYLTDILPQADD----------ISLDLLNKLLNFNPNKRLTAENCLEHPYL
  |... |.  .     |     ||. . .              .|...|.| |||.|| ||.  ||||| 
NFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase AqueK126.AA Pkinase_Tyr 13-159 27 7.2e-17 57.76 Pfam 1-159 (270) Show / Hide 
Range on Protein: 13-159
Range on HMM: 1-159/270
Sequence Identity: 27% (44 aa)

YDIKRRIGKGAYGIVWKSVDR----RTGEIVALKKIFDAFANSTD--AQRTFREILFLQAFSNHPNVIQLINVIRSSTDK-DIYLVFEFMDT-DLHAVIK
  . . .|.||.| |.| . .     |.  || |..    | . .   .  .||.  .  . .|||...|. |. .  .   ||.|.|.|   ||.   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

SK-----ILQSVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIKLADFGLAR
..      |   ..  .  | .. . | .| | |||||   |.|.... ..| .||||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase AqueK126.AA TyrKc 13-313 19 2.8e-15 24.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-313
Range on HMM: 1-280/280
Sequence Identity: 19% (65 aa)

YDIKRRIGKGAYGIVWKSVDRRTGEIVALKKIF-DAFANSTDAQRTFREILFLQAF-SNHPNVIQLINVIRSS-----TDKDIYLVFEFMDT-DLHAVIK
   .. .| ||.|.|.| . .   . || |..  ||       .   ||.  .  .  .|||...|. |....      .. ...|.|.|.  ||.  ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SKI--LQSVHMQYIMSQLCRVLKYIHSGNVIHRDLKPSNILINSECFIKLADFGLARSLASISNEGSKGAGGDGVSDFNPA----MTDY-VATRWYRSPE
..   |.  .. ... | ..   |.|| |.|||||   |.|....  .| .||||.| . .  ..|         .|   .     ... .  ||. .||
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-------ESKDYYRKKEHKGGKTMLPIRWM-APE

ILLGSRRYTRGVDMWSLGCILAEMIAS-KPLYPG--------SSTINQLDRIMSTLPPPS----RQDVESIKSPYAKAILDQIIHKRHKYLTDILPQADD
 .   ...|   | || |  . |.    .. |||        .  |..... .   .||.                                   . . |
CI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------F-VCCPD

ISLDLLNKLLNFNPNKRLTAENCLEHPYL
   ..  .  ...|..| | ...  | ..
EMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase AqueK126.AA CDC2 275-313 33 2.9e-12 33.46 In-house 254-301 (301) Show / Hide 
Range on Protein: 275-313
Range on HMM: 254-301/301
Sequence Identity: 33% (16 aa)

LTDILPQ---------ADDISLDLLNKLLNFNPNKRLTAENCLEHPYL
|..|.|.         .|.  .|||...|  .|.||..|.  |.|||.
LSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF