Gene AqueK127 (A.queenslandica)

AqueK127

Species: A.queenslandica
Alias: AqueK127
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: JNK

Sequence

Name Sequence Type Origin Length Description Download
AqueK127.AA Protein None 365 None Fasta, JSON
AqueK127.kin_dom Protein Kinase Domain None 296 None Fasta, JSON

Protein domain

Protein domains of AqueK127.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK127.AA JNK 20-315 58 1.4e-191 642.78 In-house 1-309 (309) Show / Hide 
Range on Protein: 20-315
Range on HMM: 1-309/309
Sequence Identity: 58% (180 aa)

YQDLKPLGHGAQGVVCSAKDSVRGERIAIKKLVKP--FQNETYAKRAFRELKLMKMVNHKNVIGLLNLFSPAHSIEDFEDVYIVMELMDANLCRVIG---
|| ||..| ||||.||.| | |...|.||||...|  ||| . .|||.||...|| .||||.|...| | |. ..|.|.|||||||.||.||| ||    
YQNLKFIGQGAQGIVCMAFDQVTNQRVAIKKMMRPDNFQNWMHWKRAYREFICMKCINHKNIIKMYNCFTPQETLEEFQDVYIVMEYMDWNLCQVIHSTF

IELDHDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLARAADKAFMMTPYVVTRYYRAPEVIVGMK--YKENVDIWSVGCIFAEI
 ||||.|||||.|| .||||||||.||||||||||||||..||.|||.|||.|| .| .|||||||||||||||||| ||   |||||||||||||.|| 
MELDHERMSYLFYQMCCGIKHLHSMGIIHRDLKPSNIVVNQDCTLKICDFGHARTEDPTFMMTPYVVTRYYRAPEVICGMMDNYKENVDIWSVGCIMAEM

VRGDILLPGRDYIDQWNKVTQILGTPPQEFFKQLQPSVRMYCESQ---PRHKGKSWNELFPDDVFP--NDSKED-AHKTRLAVDLLTKMLQIEPTRRVTV
.|. .| ||.|.||||||. . |||| ..| .|.||.||.| |.    |.... . .|.||| .||  ..| ..   .. .| ||| .|| | | .|  |
IRHHVLFPGKDHIDQWNKIIEFLGTPDPHFMMQMQPHVRNYVENRNMDPYYQPYNFHEHFPDTLFPDVMQSEPKDHLTCHMARDLLFRMLVINPDDRISV

DEALKHPYV
|.||.|||.
DDALQHPYI
Kinase AqueK127.AA MAPK 20-315 44 4e-175 588.08 In-house 1-328 (328) Show / Hide 
Range on Protein: 20-315
Range on HMM: 1-328/328
Sequence Identity: 44% (151 aa)

YQDLKPLGHGAQGVVCSAKDSV------RGERIAIKKLVKPFQNETYAKRAFRELKLMKMV-NHKNVIGLLNLFSP-----AHSIEDFEDVYIVMELMDA
||.|||.|.||.||||||.|         |...||||...||||.|..||..||.||...  .|.|.|.||. | |     ..|.|.|.|.|||||||..
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

NLCRVIGIE--LDHDRMSYLLYQLLCG--IKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLARAADKA---------------FMMTPYVVTRYYRAP
.|...|  .  |..|...|..||.|.|  .|..|||..||||||||||.| |.| |||.|||||| .|                 ..||.||.||.||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EVIVG---MKYKENVDIWSVGCIFAEIVR-GDILLPGRDYIDQWNKVTQILGTPPQEFFKQLQ-P-SVRMYCESQ---PRHKGKSWNELFPDDVFPNDSK
|.. .   |.|...||.||||||||| .. . .|.||.|||||||.....||||..|| .... . ..| | .|    |....|.| ..||...|     
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANF-----

EDAHKTRLAVDLLTKMLQIEPTRRVTVDEALKHPYV
   .....|.||| |||.. | .| ||.||| |||.
---NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase AqueK127.AA p38 20-315 47 5.5e-136 458.07 In-house 1-289 (289) Show / Hide 
Range on Protein: 20-315
Range on HMM: 1-289/289
Sequence Identity: 47% (145 aa)

YQDLKPLGHGAQGVVCSAKDSVRGER---IAIKKLVKPFQNETYAKRAFRELKLMKMVNHKNVIGLLNLFSP-AHSIEDFEDVYIVMELMDANLCRVIGI
||.|.|.| || | ||.| |. .|..   .||||| .||| | .|||..|||.| |. .| |||.||. | | |||..||.|||.|...|.| | ... .
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

E-LDHDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLARAADKAFMMTPYVVTRYYRAPEVIVG-MKYKENVDIWSVGCIFAEIV
. |  |.  .|.||.| | |  ||||||||||||||| | ||| |.||||||||..|.   || ||.|| |||||..   |.| . ||||||||| ||..
QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLARHCDDE--MTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELI

RGDILLPGRDYIDQWNKVTQILGTPPQEFFKQLQP-SVRMYCESQPRHKGKSWNELFPDDVFPNDSKEDAHKTRLAVDLLTKMLQIEPTRRVTVDEALKH
 | .| || |.||| .......|||..|| . .|  . | | .| | .. .   ..|            .  ...|.||| |||.. | .|.|. ||..|
TGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVF------------MGANPQAIDLLEKMLELDPDKRITAEEAMQH

PYV
|| 
PYF
Kinase AqueK127.AA CMGC 20-315 25 9.1e-126 415.58 In-house 1-513 (513) Show / Hide 
Range on Protein: 20-315
Range on HMM: 1-513/513
Sequence Identity: 25% (131 aa)

YQDLKPLGHGAQGVVCSAKDSVRG--------------ERIAIKKLVKPFQNETYAK----------RAFRELKLMKMVN-----------------HKN
|. .|..|.|. |||....|  ..              |..||||. .|| .|. ||          ||.||.|..|..|                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VIGLLNLFSPAHS------------IEDFEDVYIVMELMDANLCRVIG-----------IELDHDR------------MSYLL------YQLLCGIK--H
...|.. | . .|            . .|...|.|.|.|| .|...|            ..|..                |..      ||.|.|.|  .
IVKLYDIFYHKNSDGNEYEDKHIISQ-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

LHSAG--IIHRDLKPSNIVVKEDCSL--------------------KILDFGLARAADKA----------------------FMMTPYVVTRYYRAPEVI
.||..  ||||||||.|| . ..| |                    || ||||||. ..                        ..|.|||||.|||||..
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

VGMK----------YKENVDIWSVGCIFAEIVRG--------DILLP-----------GRDYIDQWNKVTQILGTP----------------PQEFFKQL
.|.|          | . .|.|||||||||...|        ..| |           |...|||..|  ..||||                ..|... .
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

Q---------------------PSVRMYCES---QPRHKGKSWNELFPD-------------------DVFPNDSK-----EDAHKTRLAVDLLTKMLQI
.                     ...| | .|    |....|.|..|||.                     |... |      . . . .|.||| ||||.
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSH-KFNHQFKRKCCDPQAIDLLKKMLQY

EPTRRVTVDEALKHPYV
.|..| |...||.||| 
DPDKRITAEQALQHPYF
Kinase AqueK127.AA ERK 20-315 41 5.6e-119 401.58 In-house 1-307 (307) Show / Hide 
Range on Protein: 20-315
Range on HMM: 1-307/307
Sequence Identity: 41% (133 aa)

YQDLKPLGHGAQGVVCSAKDSV-----RGERIAIKKLVKPFQNETYAKRAFRELKLMKMVN-HKNVIGLLNLFSPAHSIEDFEDVYIVMELMDANLCRVI
||..|..|||| ||||||.|        |...||||  ..| .. |.||. ||.||... . |.|.|.|.... |  |.|...|.|.| |||.  | ..|
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPN-SPEQYNDIYCVEELMETDLHQII

GIE--LDHDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLAR----AADKAF-----MMTPYVVTRYYRAPEVIVGM-KYKENVD
  .  |  |   |..||.|||.|..|||..|||||||||| | ..| ||| ||||||     ...       .|| ||.||.|||||..    || . .|
NSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMD

IWSVGCIFAEIVRGDILLPGRDYIDQWNKVTQILGTP-PQEFFKQL-QPSVRMYCESQPR--HKGKSWNELFPD-DVFPNDSKEDAHKTRLAVDLLTKML
|||.|||||| .... |.||.||..| | ..||.||| ..| ...   . .. |  ..|    ..|.| ..||. .              .|.||| |||
IWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNAN-----------CNPQAIDLLEKML

QIEPTRRVTVDEALKHPYV
.. |. | ||.|.|.||| 
VFDPDKRITVEECLEHPYF
Kinase AqueK127.AA nmo 21-315 41 2.3e-89 274.9 In-house 2-292 (292) Show / Hide 
Range on Protein: 21-315
Range on HMM: 2-292/292
Sequence Identity: 41% (125 aa)

QDLKPLGHGAQGVVCSAKDSVRGERIAIKKLVKPFQNETYAKRAFRELKLMKMVNHKNVIGLLNLFSPAHSIEDFEDVYIVMELMDANLCRVI--GIELD
|  .|.|.|| ||| |  |   | |.|.||. . |||   .|| |||||.. . .| ||. .|..  |.| .. |...|.| ||| . | ..|    .| 
QPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPH-KDFFQEIYVVTELMQSDLHKIIVSPQHLS

HDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLARA--ADKAFMMTPYVVTRYYRAPEVIVGMK-YKENVDIWSVGCIFAEIVRG
 | .   |||.| |.| ||||.|.|||.|| |..|  .| ||| ||||||    |..  ||  ||| ||||||...| . | . ||||||||||||..  
SDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLGR

DILLPGRDYIDQWNKVTQILGTPPQEFFKQLQPSVRMYCESQPRHKGKSWNELFPDDVFPNDSKEDAHKTRLAVDLLTKMLQIEPTRRVTVDEALKHPYV
 ||   .  |.| . .|..|||| .|  |.     .     .| ||  . . |.             |.|  ||.|| .||  .| .|. . .||.|||.
RILFQAQSPIQQLQMITDLLGTPSMEDMKYACEGAKAHMLRMP-HKPPCLQVLY-------TLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase AqueK127.AA ERK5 20-315 40 2.8e-87 296.29 In-house 1-295 (295) Show / Hide 
Range on Protein: 20-315
Range on HMM: 1-295/295
Sequence Identity: 40% (124 aa)

YQDLKPLGHGAQGVVCSAKDSVRGERIAIKKLVKPFQNETYAKRAFRELKLMKMVNHKNVIGLLNLFSPAHSIEDFEDVYIVMELMDANLCRVI----GI
|. .  .| || ||||||.    |...||||.   |   | ||| |||||...   | |.| . ..  |   . .. |||.|..||.. |  .|     .
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPF

ELDHDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLAR------AADKAFMMTPYVVTRYYRAPEVIVGMK-YKENVDIWSVGCI
 |.| |  | |||.| |.| .||| .|||||||||..| | | ||| |||.||      .... . || || ||.|||||... .. |   .|.||||||
TLEHIR--YFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCI

FAEIVRGDILLPGRDYIDQWNKVTQILGTPPQEFFKQLQPS-VRMYCES-QPRHKGKSWNELFPDDVFPNDSKEDAHKTRLAVDLLTKMLQIEPTRRVTV
| |..    . ||. ||.| . . ..||.||    .      |. |  .  | .. | |....|        | |    | |.|||..||  ||  |.||
FGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYP--------KAD----RQALDLLARMLRFEPSERITV

DEALKHPYV
 .||.||..
NKALQHPFL
Kinase AqueK127.AA ERK1 20-315 43 3.4e-86 292.68 In-house 1-289 (289) Show / Hide 
Range on Protein: 20-315
Range on HMM: 1-289/289
Sequence Identity: 43% (131 aa)

YQDLKPLGHGAQGVVCSAKDSVRGERIAIKKLVKPFQNETYAKRAFRELKLMKMVNHKNVIGLLNLFSPAHSIEDFEDVYIVMELMDANLCRVI-GIELD
| .|. .|.|| |.|||| | |...|.|||| . ||   || .|  ||.|...  .| |.|.. ..   |..|| . ||||| .||.  | ...   .| 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKK-ISPFEHQTYCQRTLREIKILTRFKHENIINIQDIIR-ADTIEQMRDVYIVQCLMETDLYKLLKTQHLS

HDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLARAADKAF----MMTPYVVTRYYRAPEVIVGMK-YKENVDIWSVGCIFAEIV
 | . | |||.| |.| .||| ..||||||||...   | ||| |||||| ||        .| || ||.|||||...  | |   .|||||||| ||..
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEML

RGDILLPGRDYIDQWNKVTQILGTPPQEFFK-QLQPSVRMYCESQPRHKGKSWNELFPDDVFPNDSKEDAHKTRLAVDLLTKMLQIEPTRRVTVDEALKH
    . ||. |.|| |..  .|| | |.  .  .    | | .| |  .  .|..|||.     |||        |.||| |||   | .|.||.||| |
SNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPK----ADSK--------ALDLLDKMLTFNPHKRITVEEALAH

PYV
||.
PYL
Kinase AqueK127.AA S_TKc 20-315 26 1e-82 282.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-315
Range on HMM: 1-231/231
Sequence Identity: 26% (82 aa)

YQDLKPLGHGAQGVVCSAKDSVRGERIAIKKLVKPFQNETYAKRAFRELKLMKMVNHKNVIGLLNLFSPAHSIEDFEDVYIVMELMDA---NLCRVIGIE
|. |...|.|| |.|. ...   |.. |||..          ... ||....|. .|.|.. |.  |         ...|.|||..|    .| ..|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKR

--------LDHDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLARAADKAFMMTPYVVTRYYRAPEVIVGMKYKE-NVDIWSVGC
        ..  .  ...||..|.....|| |||||||||.|| . |   .|| ||||||        | ...|..|.||||.   .|    .|.||.||
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

IFAEIVRGDILLPGRDYIDQWNKVTQILGTPPQEFFKQLQPSVRMYCESQPRHKGKSWNELFPDDVFPNDSKEDAHKTRLAVDLLTKMLQIEPTRRVTVD
|..| . |  . |      | ... ...|                                                .. | |.. |.|| .|..| |. 
ILYEMLCGYPPFP------QMQMMFKKIG------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-

EALK-------HPYV
|||.       ||..
EALQDEWDIKCHPWF
Kinase AqueK127.AA Pkinase 20-315 25 2.8e-75 261.2 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-315
Range on HMM: 1-293/293
Sequence Identity: 25% (83 aa)

YQDLKPLGHGAQGVVCSAKDSVRGERIAIKKLVKPFQNETYAKRAFR--ELKLMKMVNHKNVIGLLNLFSPAHSIEDFEDVYIVMELMDA-----NLCRV
|. ....| |. |.|. ...   |.. |.|.. |. ...   ....|  |...||..||.|.. |.  |          ..|.|||...       |...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDY

IG-------IELDHDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSL----KILDFGLARA--ADKAFMMTPYVVTRYYRAPEVIV-GMKYKE
|        . .. .     .||.|.|....|| |||||||||.|| ..... .    || |||||.     .   || ...|..|.|||||  | .|  
ISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

NVDIWSVGCIFAEIVRGDILLPGR----DYIDQWNKVTQILGTPPQEFFKQLQPSVRMYCESQPRHKGKSWNELFPDDVFPNDSKEDAHKTRLAVDLLTK
 ||.||.|||..| . |  . ||.    . .||  .. .|.|.|. . . .. .  . .  .. . .             .  ..     .. . |....
KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-------------F-HWTF-HNWSEECKDFIKW

MLQIEPTRRVTVDEALKHPYV
.|.  |..| | ...|.||..
CLCKDPKKRPTAEQILQHPWF
Kinase AqueK127.AA ERK7 20-315 35 8.5e-73 248.15 In-house 1-292 (292) Show / Hide 
Range on Protein: 20-315
Range on HMM: 1-292/292
Sequence Identity: 35% (110 aa)

YQDLKPLGHGAQGVVCSAKDSVRGERIAIKKLVKPFQNETYAKRAFRELKLMKMVN-HKNVIGLLNLFSPAHSIEDFEDVYIVMELMDANLCRVIG-IEL
|. .| || || |.|  | |   .. .|.||    |.|.| | | |||  ...  . | |.| |.| .      .   |.|.| | |.. |  ||   ..
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVI----RADNDRDIYLVFEFMETDLHAVIRKGNI

DHD-RMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLARA-------ADKAFMMTPYVVTRYYRAPEVIVG-MKYKENVDIWSVGCI
  |    | .||||  ||..||. .|||||||||| .  .| .|. ||||||        ...  |.| || || |||||. .|  .|   || ||.|||
LKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCI

FAEIVRGDILLPGRDYIDQWNKVTQILGTPPQEFFKQLQPSVRMYC-ESQPRHKGKSWNELFPDDVFPNDSKEDAHKTRLAVDLLTKMLQIEPTRRVTVD
 .|..||  . ||   ..| .|. .... | ||  . .......   |. ...| |. ....| .  ..           |.||| ..|.  | .|.|..
LGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMP-QCCDD-----------AIDLLKRLLVFNPKKRLTAE

EALKHPYV
.||.||||
QALQHPYV
Kinase AqueK127.AA MAPK-Unclassified 20-168 40 7.7e-51 175.21 In-house 1-157 (575) Show / Hide 
Range on Protein: 20-168
Range on HMM: 1-157/575
Sequence Identity: 40% (64 aa)

YQDLKPLGHGAQGVVCSAKDSVR-GERIAIKKLVKPFQNETYAKRAFRELKLMKMVNHKNVIGLLNLFSPAHSIE-DFEDVYIVMELMDA---NLCRVI-
|   | .| || |.|| |.|.   .   ||||. . |.|.| .||. ||. .    || |.| . . | .      .| |.||||..|     .|  .| 
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQIIK

-GI-ELDHDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLAR
  .  . |    |..||.| |.| ||||.||||||||||. . .|||..| |||..|
SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase AqueK127.AA MAPK-Unclassified 176-315 32 9.7e-33 115.09 In-house 405-575 (575) Show / Hide 
Range on Protein: 176-315
Range on HMM: 405-575/575
Sequence Identity: 32% (56 aa)

MTPYVVTRYYRAPEVIVGMK-YKENVDIWSVGCIFAEIVRG-----------DILLPGRD--------------------YIDQWNKVTQILGTPPQEFF
|| |||||.||||| .  |. |   |||||.|||||| .              .|.||.|                    ..|| .     ||.||.|  
MTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDC

KQLQ-PSVRMYCESQPRHKGKSWNELFPDDVFPNDSKEDAHKTRLAVDLLTKMLQIEPTRRVTVDEALKHPYV
   . .|.| | .|  . .   . .|..  .  .|         .. |.. ||||. | .| | |.||.|||.
NFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDD--QIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase AqueK127.AA TyrKc 20-318 20 3e-13 -8.43 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-318
Range on HMM: 1-280/280
Sequence Identity: 20% (68 aa)

YQDLKPLGHGAQGVVCSAKDSVRGERIAIKKLVKPFQNETYAKRAF-RELKLMKMV--NHKNVIGLLNLFSPAHSIEDF------EDVYIVMELMDA---
 . .| ||.|| |.|. .. .   .  |.|.| .        ...| ||...|...  .|.|.. |.     .  ....      | ..||||.|.    
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLY-----GVCTQQGRNFMYIEPLMIVMEYMPHGDL

-NLCRVIGIELDHDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLARAADKA---------FMM-----TPYVVTRYYRAPEVIV
 .  |  . .| .. . .  .|  ||  .||| ..|||||   |. |.|.   || ||||.|. .            ..     . ...     |||.| 
KDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

GMKYKENVDIWSVGCIFAEIV-RGDILLPG-----RDYIDQWNKVTQI--LGTPPQ----EFFKQLQPSVRMYCESQPRHKGKSWNELFPDDVFPNDSKE
  |. .  |.|| |    ||  .|.   ||      . ..  ..| |   .  ||                                          .  
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------------------F--

DAHKTRLAVDLLTKMLQIEPTRRVTVDEALKHPYVSIW
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-VCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase AqueK127.AA Pkinase_Tyr 131-169 48 0.00348 11.41 Pfam 122-160 (270) Show / Hide 
Range on Protein: 131-169
Range on HMM: 122-160/270
Sequence Identity: 48% (19 aa)

CGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLARA
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KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase AqueK127.AA Pkinase_Tyr 20-105 26 0.026935 8.4 Pfam 1-89 (270) Show / Hide 
Range on Protein: 20-105
Range on HMM: 1-89/270
Sequence Identity: 26% (25 aa)

YQDLKPLGHGAQGVVCSAKDS----VRGERIAIKKLVKPFQNETY--AKRAFRELKLMKMV-NHKNVIGLLNLFS-PAHSIEDFEDVYIVMELM
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ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN----QIYIVMEYM