Gene AqueK159 (A.queenslandica)

AqueK159

Species: A.queenslandica
Alias: AqueK159
External Links:
Annotation:

Classification

Group: Other
Family: IRE

Sequence

Name Sequence Type Origin Length Description Download
AqueK159.AA Protein None 538 None Fasta, JSON
AqueK159.kin_dom Protein Kinase Domain None 148 None Fasta, JSON

Protein domain

Protein domains of AqueK159.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK159.AA IRE 59-206 32 2.5e-31 105.6 In-house 138-292 (292) Show / Hide 
Range on Protein: 59-206
Range on HMM: 138-292/292
Sequence Identity: 32% (52 aa)

IHRDIKPGNILLVQ--KSSSS-EVKAVLADFGISTELNEREAVTRQ--RGRRTDT--WMAPELLLDDLTDCKFSRESDIFSMGCIIYYVLTKGRHPFNKG
.|||.|| |||  .   ...  .......||| .  |.|     .   |   |.|  |..||.|.  ..    ..  |||||||..|||.|.| |||  |
VHRDLKPHNILIHMNRPNQHGENNRFMISDFGLCKMLVEGRYSFTRNIRSGPTGTWGWHPPEMLQE-FCQKRKTKSVDIFSMGCVFYYVMTNGQHPF--G

HDNDYTVHQNIKN--YMICDFQLLNDKP--VARALIKNMMKHNKDSRPSASEVLDDPYF
 |. .    || .  | .  .. .|.    .|. ||. |  |. ..||...|.|  |.|
NDK-LHRQANILKGKYNLDQLKHHNHWHIVIACDLIHQMIHHDPQKRPTIKECLNHPFF
Kinase AqueK159.AA Pkinase 59-206 24 1.1e-25 91.86 Pfam 130-293 (293) Show / Hide 
Range on Protein: 59-206
Range on HMM: 130-293/293
Sequence Identity: 24% (42 aa)

IHRDIKPGNILLVQKSSSSEVKAVLADFGISTE--LNEREAVTRQRGRRTDTWMAPELLLDDLTDCKFSRESDIFSMGCIIYYVLTKGRHPFNKGH----
||||.|| |||....   .. .  ..|||..    .   .  |   |  |  .||||...   .. . ....|..|.|||.|..|. || ||  ||    
IHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFDY-NNS-MTTFCG--TPWYMAPEVIR---GGQYYGPKVDMWSCGCILYEMLC-GRPPFP-GHCWHD

--DNDYTVHQNIKNYMICDFQLLNDK------------------PVARALIKNMMKHNKDSRPSASEVLDDPYF
  | .. . .. .     |.. ....                  . .. .||.. . .  .||.| ..| .|.|
NHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK159.AA Ciliate-E2 59-206 19 1.2e-24 81.46 In-house 183-365 (365) Show / Hide 
Range on Protein: 59-206
Range on HMM: 183-365/365
Sequence Identity: 19% (40 aa)

IHRDIKPGNILLVQKSSSSEVKAVLADFGISTELNEREAVTRQRGRR-------------------------------TDTWMAPELLLDDLTD-----C
||||||| |||.            ..|||.|..... .  ... ...                               |   |||| |     |      
IHRDIKPENILF----------IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQK

KFSRESDIFSMGCIIYYVLTKGRHPFNKGHDNDYTVHQNIKNYMICDFQ-------------------LLNDKPVARALIKN----MMKHNKDSRPS-AS
  . ..||.|.|.|.|. |. |..||             ... . |...                    ..  . .  |||.    |.. . . |.. ..
GYDYKCDIWSLGVILYEMLF-GKPPF-------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWE

EVLDDPYF
..|. |.|
QILNHPWF
Kinase AqueK159.AA CAMK 59-206 17 3.5e-24 74.22 In-house 201-425 (425) Show / Hide 
Range on Protein: 59-206
Range on HMM: 201-425/425
Sequence Identity: 17% (39 aa)

IHRDIKPGNILLVQKSSSSE------------VKAVLADFGISTELNE------------------------REAVTRQRGRRTDTWMA-PELLLD----
.|||.|| ||||......|.             .  ..||| ......                         .  . . |  |   || ||.|.     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG--TPEYMAAPEVLNGKGHC

------DLTDCKFSRESDIFSMGCIIYYVLTKGRHPFNKGHDN--------DYTVHQNIKNYMICDFQLLNDK-------------------------PV
      | .    ....|. |.|.| |  |. |. ||.  .||        ... ..  .. | ....   ..                         . 
NMQNATDEEKPYYGPKCDMWSCGVILYIMLC-GYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQE

ARALIKNMMKHNKDSRPSASEVLDDPYF
.. ||..|.. . . |......|..| .
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK159.AA TKL 59-202 19 2.8e-20 69.71 In-house 162-362 (364) Show / Hide 
Range on Protein: 59-202
Range on HMM: 162-362/364
Sequence Identity: 19% (39 aa)

IHRDIKPGNILLVQKSSS---------SEVKAVLADFGISTELNEREAVTR-----------------QRGRR-TDTWMAPELLLDDLTDC---------
||||.|. |||. ..            ..... ..|||.|.......  ..                    .. |  |||||.| ... ..         
IHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFC

---KFSRESDIFSMGCIIYYVLTKGRHPFNKGHDNDYTVHQ---NIKNYMICDFQL-----------------LNDKPVARALIKNMMKHNKDSRPSASE
   ..|  .|..|.| ... .||  |    ......  . |    .  .|.|| .|                  .  |  . |..  ..|. ..|||..|
KGFEYSEKCDVYSFGIVLWEILTRCR--PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQE

VLD
.|.
ILK
Kinase AqueK159.AA STE 59-206 22 5.9e-20 67.23 In-house 174-359 (359) Show / Hide 
Range on Protein: 59-206
Range on HMM: 174-359/359
Sequence Identity: 22% (44 aa)

IHRDIKPGNILLVQKSSSSEVKAVLADFGISTELNE---------------REAVTR--QRGRRTDTWMAPELLLDDLTD--CKFSRESDIFSMGCIIYY
|||||||.||||          . |.|||... |..                 .  |    |     ||||| .. . ..   . .. .|| | || |  
IHRDIKPANILL----------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP---WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIE

VLTKGRHPFNKGHDNDYTVHQNIKNYMI----------CDFQLLNDK---------------------PVARALIKNMMKHNKDSRPSASEVLD--DPYF
 .| |..|. ..|.     . .....|            .   | |.                     |  .  |..  . . . ||.||. |    | .
MAT-GKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK159.AA Ciliate-E2-Unclassified 59-206 24 9e-20 65.27 In-house 166-352 (352) Show / Hide 
Range on Protein: 59-206
Range on HMM: 166-352/352
Sequence Identity: 24% (47 aa)

IHRDIKPGNILLVQKSSSSEVKAVLADFGISTELNEREAVTRQRG---------------RRTDTWM----APELLLDDLTDCKFSRESDIFSMGCIIYY
||||||| |||. .. .    .  ..||||| .... .  .  ..                 |   |    |||.|     | . . ..||.|.|.|.|.
IHRDIKPENILFDNNGK--NYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYE

VLTKGRHPFNKGHDNDYT--------------VHQNIKNYMICDFQLLN------DKPVARALIK----NMMKHNKDSRPSASEVLDDPYF
 |. |..||.   ....               ..||||.  |. .   .        | |  .|.     |.| | ..|......|  |.|
MLF-GYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase AqueK159.AA PLK1 54-206 28 8.2e-16 48.21 In-house 116-253 (253) Show / Hide 
Range on Protein: 54-206
Range on HMM: 116-253/253
Sequence Identity: 28% (44 aa)

SSTRTIHRDIKPGNILLVQKSSSSEVKAVLADFGISTELNER-EAVTRQRGRRTDTWMAPELLLDDLTDCKFSRESDIFSMGCIIYYVLTKGRHPFNKGH
. .. ||||.| ||. | .     ...  . |||. |....  |      |  |  ..|||.    |..   | | ||.|.|||.| .|  |. ||    
HNNKIIHRDLKLGNLFLND-----HLQVKIGDFGLATKCEYDGERKKTLCG--TPNYIAPEV----LNKKGHSFEVDIWSIGCIMYILLF-GQPPFETKC

DNDYTVHQNIKNYMICDFQLLNDKPVARALIKNMMKHNKDSRPSASEVLDDPYF
 ..  ..    .|.| .      ...|. ||..|.. . ..|| ...|| | .|
LKETYSRIKKNEYRIPSHI----SQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase AqueK159.AA ULK 59-206 26 2.3e-15 50.15 In-house 152-329 (329) Show / Hide 
Range on Protein: 59-206
Range on HMM: 152-329/329
Sequence Identity: 26% (48 aa)

IHRDIKPGNILLVQK--------SSSSEVKAVLADFGISTELNER-----EAVTRQ-----RGRRTDTWMAPELLLDDLTDCKFS-RESDIFSMGCIIYY
||||||| |||.  .        . . .. . .|||| .  ...       ..|       .|  |   |||..| . .  ....  ..||.|.|||.|.
IHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCG--TPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYE

VLTKGRHPFNKGHDNDYT---VHQNIKNY-----MICDFQLLNDK--------PVARALIKNMMKHNKDSRPSASEVLDDPYF
 |. |. ||..   ||.    . ..|.|.     .|....|  .|        |  . ||. |.. . . | |  |... | |
MLY-GKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase AqueK159.AA ULK 59-206 24 7.7e-15 49.14 In-house 148-324 (324) Show / Hide 
Range on Protein: 59-206
Range on HMM: 148-324/324
Sequence Identity: 24% (45 aa)

IHRDIKPGNILLVQK--------SSSSEVKAVLADFGISTELNEREAVTRQR----------GRRTDTWMAPELLLDDLTDCKFS-RESDIFSMGCIIYY
||||||| |||.  .        . . .. . .|||| .  ... .    ..          |  |   |||..| . .  ....  ..||.|.|||.|.
IHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKG--TPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYE

VLTKGRHPFNKGHDNDYT--VHQNIKN-----YMICDFQL-LNDK-------PVARALIKNMMKHNKDSRPSASEVLDDPYF
 |. |. ||..   ||.   . . |.|     ..|.. ..  ...       |  . ||. |.. . . | |  |... | |
MLY-GKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase AqueK159.AA STE-Unique 59-137 20 6.5e-14 45.27 In-house 427-543 (616) Show / Hide 
Range on Protein: 59-137
Range on HMM: 427-543/616
Sequence Identity: 20% (24 aa)

IHRDIKPGNILLVQKSSSSEVKAVLADFGISTELNER-------------------------------------EAVTRQRGRRTDTWMAPELLLDD-LT
||||.||.||.. |.      |....|||..|.. .                                      . .|. ... | ..|.|| ..     
IHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKDNNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRNQI

DCKFSRESDIFSMGCII
   ... .||.| ||..
NNPYDTKVDIWSLGCMC
S_TKc AqueK159.AA S_TKc 1-206 17 2.1e-11 -9.61 SMART 16-231 (231) Show / Hide 
Range on Protein: 1-206
Range on HMM: 16-231/231
Sequence Identity: 17% (46 aa)

MLARDQP----------RDFTWLSLLASLNRELEVEA-------------------------EG--SSLLHISHTSPCPC----AKIMATSYPSSST---
...|.            .         .. ||...                           .|   .|... .  ...          . .    .   
YKCRHKKTGRIVAIKIIK--------EHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCA

-------RTIHRDIKPGNILLVQKSSSSEVKAVLADFGISTELNEREAVTRQRGRRTDTWMAPELLLDDLTDCKFSR-ESDIFSMGCIIYYVLTKGRHPF
       . ||||.|| |||| .          ..|||....|     .|.        .||||.|       .... ..|. | |||.|  |. |. ||
LEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-TTFCGTPW-------YMAPEVL-------GYGKCKCDWWSCGCILYEMLC-GYPPF

NKGHDNDYTVHQNIKNYMICDFQLLNDKPVARALIKNMMKHNKDSRPSASEVLD-------DPYF
     ..... ..|.             | |. .|..... . . ||.| |.|        .|.|
P----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc AqueK159.AA TyrKc 13-204 14 3.9e-05 -139.57 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-204
Range on HMM: 1-280/280
Sequence Identity: 14% (41 aa)

LSLLASLNR------------------------ELEVEAEGSSLLHI--SH----------TSP-------CPCAKIMAT----------SYPS------
..|.  | .                        . .   | . . ..  .|          |..        |   .|             ..       
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

----------------SSTRTIHRDIKPGNILLVQKSSSSEVKAVLADFGISTELNER------EAVTRQ----RGR--RTDTWMAPELLLDDLTDCKFS
                .| . ||||.   |.|.  .       .  .||| | .. .       . . |.     |.      ||||| .     ..||.
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NYGKFT

RESDIFSMGCIIYYVLTKGRHPFNK-GH--DNDYTVHQNIKNYMICDFQLL--------NDKPVARALIKNMMKHNKDSRPSASEVLDDP
 .||..| |  .. ..| |  |         ... |....|. .  .              . . . ..|   ... ..||. ||. .. 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF