Gene AqueK165 (A.queenslandica)

AqueK165

Species: A.queenslandica
Alias: AqueK165
External Links:
Annotation:

Classification

Group: Other
Family: IRE

Sequence

Name Sequence Type Origin Length Description Download
AqueK165.AA Protein None 1333 None Fasta, JSON
AqueK165.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of AqueK165.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc AqueK165.AA S_TKc 341-603 24 1.1e-43 152.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 341-603
Range on HMM: 1-231/231
Sequence Identity: 24% (67 aa)

FDKKLLLGKGASSTVHKGTFKE--EDVAVKRMKEELSDEYKELLLNIKHKNIVLVLCIESYQGLDHIVLELCLA---SFHQYFKEFEKVMNKFNGLTVVK
...  ..|||| ..|.|.. |.  . ||.|..| |      ..| . .|.|||  . .    .  ..|.|.|     . ..| |.  .  ..|     . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA

KDVNQDAVRGLEYLHEQNIVHRDIKPGNILLVQKSSSSEVKAVLADFDLSTKLDDDRSLKTTLNKRGTLSWMAPELLVKDGLELQFSL-QSDIFSMGCVI
. . .  ...|||.|...|.|||.|| |||| .          ..|| |...|             ||. .||||.|       ...   .|. | ||..
RFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL---------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCIL

YFAETDGNHPFDTGDSRGAAIHQNVKNYNPCDFHPLNGKPKATALIFKMITRDRASRPSASEVLD-------DRYF
|   . |  ||.      ... ....             | |  .| |. ..| . ||.| |.|        . .|
YEMLC-GYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK165.AA TKL 347-535 19 5.1e-39 135.95 In-house 1-280 (364) Show / Hide 
Range on Protein: 347-535
Range on HMM: 1-280/364
Sequence Identity: 19% (58 aa)

LGKGASSTVHKGTFKE----------EDVAVKRMKEELSD-----------------------------EYKE----LLLNIKHKNIVLVLCIESYQGL-
.|.|....|.||...           .|||||..|.. .|                             . .|    ......| |||. . .  . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------DHIVLELC-LAS-FHQYFKEFEKVMNKFNGLTVVKKDVNQDAVRGLEYLHEQN--------IVHRDIKPGNILLVQKSSS--------
             .|| |.|   | .|..                .. .  .|. ||..||| .|        |.|||.|. |||. ..           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNP

-SEVKAVLADFDLSTKLDDD-----------------RSLKTTLNKRGTLSWMAPELLVKDGL------------ELQFSLQSDIFSMGCVIY
 ..... ..|| ||. .. .                 .. ||| ...||. |||||.| ...             ....| ..|..|.| |..
NADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLW
Kinase AqueK165.AA IRE 344-603 28 1e-36 124.57 In-house 1-292 (292) Show / Hide 
Range on Protein: 344-603
Range on HMM: 1-292/292
Sequence Identity: 28% (86 aa)

KLLLGKGASST-VHKGTFKEED-VAVKRMKEELSDEYK---ELLL---NIKHKNIVLVLCIESYQGLDHIVLELCLASFHQYFKE------FEKVMNKFN
.  ||.|.. | | ||.. . . ||||.|  |  .  .   ..|    . .|.|..   | |. .    . |||| .|   |          ..  |. |
NNILGRGCNGTLVFKGIWNGRIPVAVKQMQKEFNPFISREIQMLIKLESDNHPNVIRYYCQEEDDQFVYLALELCQGSLQDYVEQKKRNNFINSSNNSNN

GLTVVK------------KDVNQDAVRGLEYLHEQNIVHRDIKPGNILLVQ--KSSSS-EVKAVLADFDLSTKLDDDRSLKTT--L-NKRGTLSWMAPEL
... ..            ... .... ||..|| |||||||.|| |||  .   ...  .......|| |. .|. .|.  |.  . .  ||  |..||.
NNKNNNNNNNQWQIHIRMWQLIKQCMNGLQHLHSQNIVHRDLKPHNILIHMNRPNQHGENNRFMISDFGLCKMLVEGRYSFTRNIRSGPTGTWGWHPPEM

LVKDGLELQFSLQSDIFSMGCVIYFAETDGNHPFDTG-DS--RGAAIHQNVKNYNPCDFHPLNGKP--KATALIFKMITRDRASRPSASEVLDDRYF
|  .. .   .   ||||||||.|.  | |.|||  | |.  | | |  .  | ..  ....|      |. || .||  |  .||...|.|   .|
LQEFC-QKRKTKSVDIFSMGCVFYYVMTNGQHPF--GNDKLHRQANILKGKYNLDQ--LKHHNHWHIVIACDLIHQMIHHDPQKRPTIKECLNHPFF
Pkinase AqueK165.AA Pkinase 341-603 20 2e-31 112.17 Pfam 1-293 (293) Show / Hide 
Range on Protein: 341-603
Range on HMM: 1-293/293
Sequence Identity: 20% (63 aa)

FDKKLLLGKGASSTVHKGTFKEED--VAVKRMKEELSDEYK----------ELLLNIKHKNIVLVLCIESYQGLDHIVLELCLASFHQYFKEFEKVM---
. ..  .|.|....| |.. | .   ||||..| .  .. |          .......|.|||  ...  . .  ..|.|.|    .  .  |. ..   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

NKFN--GLTVVKKDVNQDAVRGLEYLHEQNIVHRDIKPGNILLVQKSSSSEVKAVLADFDLSTKLDDDRSLKTTLNKRGTLSWMAPELLVKDGLELQFSL
..       ..|. . |  .|||||.|...|.|||.|| |||....   .. .  ..|| |. ..|   .   .    ||. .||||..         . 
HGCFYFSEWECKFYMYQ-ILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR---GGQYYGP

QSDIFSMGCVIYFAETDGNHPFDTGD------SRGAAIHQNVK--NYNPCDFHPLNGK----------------PKATALIFKMITRDRASRPSASEVLD
 .|..|.||..|   . |. ||. |.      .  . | .. .  .  ...    .                  . .  .| .....| ..||.| ..| 
KVDMWSCGCILYEMLC-GRPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

DRYF
. .|
HPWF
Kinase AqueK165.AA Ciliate-E2 445-603 23 3.3e-27 90.45 In-house 172-365 (365) Show / Hide 
Range on Protein: 445-603
Range on HMM: 172-365/365
Sequence Identity: 23% (50 aa)

GLEYLHEQN-IVHRDIKPGNILLVQKSSSSEVKAVLADFDLSTKLDDD---------RSLKTTLN---------------------KRGTLSWMAPELLV
.|||||..| |.|||||| |||.            ..|| ||.|.|||         . ...  .                       ||.  |||| | 
ALEYLHSKNNIIHRDIKPENILF----------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILN

KDG-----LELQFSLQSDIFSMGCVIYFAETDGNHPFDTGDSRGAAIHQNVKNYNPCDFH-----------------PLNGKPKATALIFK----MITRD
. .     .. . . ..||.|.|...|.  . |..||           |. .  ...||                  ...  ...  || |    |. .|
GKKYDNQQKQKGYDYKCDIWSLGVILYEMLF-GKPPF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKD

RASRPS-ASEVLDDRYF
   |.. ....|.  .|
PEKRITGWEQILNHPWF
Kinase AqueK165.AA CAMK 443-603 17 7.2e-27 83.01 In-house 189-425 (425) Show / Hide 
Range on Protein: 443-603
Range on HMM: 189-425/425
Sequence Identity: 17% (41 aa)

VRGLEYLHEQNIVHRDIKPGNILLVQKSSSSE------------VKAVLADFDLSTKLDDDRSLK---------------------TTLNKRGTLSWMA-
. ...|.|..||||||.|| ||||......|.             .  ..|| ...|.|.. ...                           ||.. || 
CSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAA

PELLVK----------DGLELQFSLQSDIFSMGCVIYFAETDGNHPFD--TGDS---------RGAAIHQNVKNYNPC-DFHPLNGKP------------
||.| .          |. .   . ..|. |.|.. |.  . |  ||.  ....             ....... .   . ... . .            
PEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLC-GYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDIS

---------KATALIFKMITRDRASRPSASEVLDDRYF
          .  || || ..|   |......|..  .
DEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK165.AA STE 440-603 22 2.6e-26 89.98 In-house 158-359 (359) Show / Hide 
Range on Protein: 440-603
Range on HMM: 158-359/359
Sequence Identity: 22% (48 aa)

QDAVRG-LEYLHEQNIVHRDIKPGNILLVQKSSSSEVKAVLADFDLSTKLDDD--------------RSLKTTLNKRGTLSWMAPELLVKDGLE--LQFS
.. ..| |.|||...|.||||||.||||          . |.|| ....|.|.               . . .    ||  ||||| . ..|     . .
RQILKGLLYYLHSHHIIHRDIKPANILL----------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD

LQSDIFSMGCVI---------YFAETDGNHPFDTGDSRGAA-----IHQNVKNYNPCDFHPLNGK-----------------PKATALIFKMITRDRASR
 ..|| | ||.|         .. ...    | . .. ...     . . |..  |   ..|  .                 |.    | |  ..|   |
TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKR

PSASEVLD--DRYF
|.||. |      .
PTASQLLKSEHPFI
Kinase AqueK165.AA Ciliate-E2-Unclassified 341-603 19 3e-24 81.05 In-house 1-352 (352) Show / Hide 
Range on Protein: 341-603
Range on HMM: 1-352/352
Sequence Identity: 19% (69 aa)

FDKKLLLGKGASSTVHKGTFKEED-------------VAVKRMKEELSDEYKE---------------------LLLNIKHKNIVLVLCIESYQGLDHIV
. .   .|.|. ..|.|   |...             ...| ....  ..  |                     .|||..| .||  . ..  .    ||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LELC----LASFHQYFKE--------FEKVMN-KFNGLTVVK----KDVNQDAVRGLEYLHEQN-IVHRDIKPGNILLVQKSSSSEVKAVLADFDLSTKL
.|.|    |  ... .|         |.. .. |      .|    |.     . ||||||..| |.|||||| |||. .. .    .  ..|| .| |.
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--NYYIKIIDFGISKKY

DDDRSL-------------KTTLNKRGTLSWM----APELLVKDGLELQFSLQSDIFSMGCVIYFAETDGNHPFD--TGDS------------RGAAIHQ
....               . .  . ||.. |    |||.| . . . . . ..||.|.|...|.  . |..||.  . ..            .   ..|
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLF-GYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

NVKNYNPCDFHPLN-----GKPKAT-----ALIFKMITRDRASRPSASEVLDDRYF
| |. |.. ..  .     . ..        |. ||.  .  .|......|   .|
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase AqueK165.AA C8 407-534 31 2.4e-21 70.89 In-house 99-226 (226) Show / Hide 
Range on Protein: 407-534
Range on HMM: 99-226/226
Sequence Identity: 31% (41 aa)

LELCLASFHQYFKEFEKVMNKFNGLTVVKKDVNQDAVRGLEYLHEQNIVHRDIKPGNILLVQKSSSS-EVKAVLADFDLSTKLDDDRSLKTTLNK--RGT
.|||   ..|...|. .   .|.     |  .    . |..|.|  ||.|||||| |.|.  . ..  |.|  |.||...... ...|   . .    ||
MELCEQNLKQLYDERRNKQQQFS--KEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIK--LCDFGFASQVSKNKSHIQSKKMNTCGT

LSWMAPELLVK-DGLELQFSLQSDIFSMGCVI
. ..||| . | |    |.. |||.||.| | 
WAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase AqueK165.AA TKL-Unique 434-535 30 1.3e-20 69.59 In-house 111-219 (290) Show / Hide 
Range on Protein: 434-535
Range on HMM: 111-219/290
Sequence Identity: 30% (35 aa)

VKKDVNQDAVRGLEYLHEQN--IVHRDIKPGNILLVQKSSSSEVKAVLADFDLSTKLDDDRSLKTTLNKR---------GTLSWMAPELLVKDGLELQFS
.. . ..|...|..|||  .  | |||.|. |.|....| . |... ..|| ||. ..  ...|.|.|           |.. |||||.|   ... |.|
QRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNS--KINKMTNNEHKGTRNQTRCGSFRWMAPEVL--RMNFCQYS

LQSDIFSMGCVIY
 .||..| | | .
EKSDVYSFGIVLW
Kinase AqueK165.AA ULK 443-603 26 4.8e-18 59.64 In-house 140-329 (329) Show / Hide 
Range on Protein: 443-603
Range on HMM: 140-329/329
Sequence Identity: 26% (51 aa)

VRGLEYLHEQNIVHRDIKPGNILLVQK--------SSSSEVKAVLADFDLSTKLDDD----RSLKTTLN---KRGTLSWMAPELLVKDGLELQFS-LQSD
. |. .||..||.|||||| |||.  .        . . .. . .||| .. ..|.|    . ..|..|    .||   |||..| . | . ...   .|
LNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCD

IFSMGCVIYFAETDGNHPFDTGDSRGAA---IHQNVKNYNPCD----FHPLNGK---------PKATALIFKMITRDRASRPSASEVLDDRYF
|.|.||..|   . |  || .   .      | ....|..|.      .||. .         |.   || .|...|.  | |  |...   |
IWSLGCIFYEMLY-GKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase AqueK165.AA ULK 443-535 29 2.6e-17 58.01 In-house 136-243 (324) Show / Hide 
Range on Protein: 443-535
Range on HMM: 136-243/324
Sequence Identity: 29% (32 aa)

VRGLEYLHEQNIVHRDIKPGNILLVQK--------SSSSEVKAVLADFDLSTKLDDD----RSLKTTL---NKRGTLSWMAPELLVKDGLELQFS-LQSD
. |. .||..||.|||||| |||.  .        . . .. . .||| .. ..|..      ..|..     .||   |||..| . | . ...   .|
CNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCD

IFSMGCVIY
|.|.||..|
IWSLGCIFY
Kinase AqueK165.AA TyrKc 341-601 21 1.4e-12 -19.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 341-601
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

FDKKLLLGKGASSTVHKGTFKEEDVAVKRMKEELSDEYKELL------LNI--KHKNIVLVL--CIES-----YQGLDHIVLELC-LASFHQYFKEFEKV
  ..  || ||  .|.||| | ..|||| .||.     ....       ..  .|.|||  .  |...     | .   ||.|.. . . ..| .. .. 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

MNKFNGLTVVKKDVNQDAVRGLEYLHEQNIVHRDIKPGNILLVQKSSSSEVKAVLADFDLSTKLDDD-------RSLKTTL--NKR--GTLSWMAPELLV
       .  . .   .. .| ||||..|..|||.   |.|.  .       .  .|| || ...||          ...   ...    . ||||| . 
-----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

KDGLELQFSLQSDIFSMGCVIYFAETDGNHPFDT---GDSRGAAIHQNVKNYNPCDFHPLN-------GKPKATALIFKMITRDRASRPSASEVLDDR
    .  |. .||..| | ...   |.|  |       .   . ....||. .  .  | .         ..   .. .   .| ..||. ||. .. 
---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK165.AA CAMK 346-391 11 1.6e-07 19.58 In-house 1-101 (425) Show / Hide 
Range on Protein: 346-391
Range on HMM: 1-101/425
Sequence Identity: 11% (12 aa)

LLGKGASSTVHKGTFKEED--------------VAVKR-----------------------------------MKEELSDEYKELLL------NIKHKNI
 ||.|. ..|.... |.                ||.|                                    .....  |.. . .      ...|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

V
.
I
Kinase AqueK165.AA TKL-Unique 346-392 28 9.4e-07 20.04 In-house 4-60 (290) Show / Hide 
Range on Protein: 346-392
Range on HMM: 4-60/290
Sequence Identity: 28% (16 aa)

LLGKGASSTVHKGTFKEEDVAVKRMK--EELSDE-----YKEL--LLNIK-HKNIVL
..| |....| ||... ..||.|. .  |..| |     ..|.  . ... |.|||.
KIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVH
Kinase AqueK165.AA STE 341-391 19 1.6e-05 15.57 In-house 1-93 (359) Show / Hide 
Range on Protein: 341-391
Range on HMM: 1-93/359
Sequence Identity: 19% (18 aa)

FDKKLLLGKGASSTVHKGTFKEED-----------------VAVKRMK---------------------EELSDEYKEL--LLNIK--HKNIV
...   .||||. ||.|.  .. .                 .|.|.|.                     ||. .  ||.  . . .  |.|||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIV
Kinase AqueK165.AA ULK 341-391 23 8.1e-05 12.84 In-house 1-81 (329) Show / Hide 
Range on Protein: 341-391
Range on HMM: 1-81/329
Sequence Identity: 23% (19 aa)

FDKKLLLGKGASSTVHKGT---FK---EEDVAVKRMK-EELSDEYKE---------------LLLNIK----HKN----IV
. ..  ||||.  .|.||.    |    |.||.| .  .... ...|               ..  .|    |||    ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIV
Kinase AqueK165.AA Pkinase_Tyr 444-535 26 0.000113 16.45 Pfam 122-205 (270) Show / Hide 
Range on Protein: 444-535
Range on HMM: 122-205/270
Sequence Identity: 26% (25 aa)

RGLEYLHEQNIVHRDIKPGNILLVQKSSSSEVKAVLADFDLSTKL-DDDRSLKTTLNKRGTLSWMAPELLVKDGLELQFSLQSDIFSMGCVIY
.|.|||...|..|||.   |.|.       . ..  .|| |.  . .||  .... . .    ||||| .        |. .||. | | ...
KGMEYLESKNCIHRDLAARNCLVTE-----NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK----FTTKSDVWSFGVLMW
Pkinase_Tyr AqueK165.AA Pkinase_Tyr 339-384 37 0.000115 16.42 Pfam 1-52 (270) Show / Hide 
Range on Protein: 339-384
Range on HMM: 1-52/270
Sequence Identity: 37% (20 aa)

FQFDKKLLLGKGASSTVHKGTFK------EEDVAVKRMKEELSDEY--KELLLN
 .|.||  ||.||  .|.||| |      . .|||| .||  ..|   .| ...
ITFGKK--LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR
Kinase AqueK165.AA ULK 341-391 24 0.000137 12.28 In-house 1-78 (324) Show / Hide 
Range on Protein: 341-391
Range on HMM: 1-78/324
Sequence Identity: 24% (19 aa)

FDKKLLLGKGASS-TVHKG----TF-KEEDVAVKRMK-----EELSD---EYKELLLN--------IK---HKN--IV
. ..  ||||.   .|.||    |  . ..||.| .      .  ..   .|   ||.        .|   |.|  ||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIV
Kinase AqueK165.AA Ciliate-E2 341-391 13 0.000215 10.97 In-house 1-95 (365) Show / Hide 
Range on Protein: 341-391
Range on HMM: 1-95/365
Sequence Identity: 13% (13 aa)

FDKKLLLGKGASSTVHKGTFKEED-------------------------VAVKRM----KEELSDEYKEL---------------LLNIKHKNIV
...  ..|.|. ..| |.. ....                         .|.|.|    .|... | ...               | ...|.||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNII
PNP_UDP_1 AqueK165.AA PNP_UDP_1 1081-1329 15 1.2e-09 32.49 Pfam 1-247 (247) Show / Hide 
Range on Protein: 1081-1329
Range on HMM: 1-247/247
Sequence Identity: 15% (42 aa)

RILLMTATDVELRGVLGYLKPLDGW--DKVIKSFIN--NTRIYVGKC--GGYSVVVGRSANAKSQQGGLDAL--TITNKIMEIFKPKYIIAVGICFGMDR
||......       |.... |  .   . .. .      ..|.|.   ||  ||. .. .     |   |   . .   |. |... ||..|.| |. .
RIGIICGMP------LEEVA-LAEHIPYDDTPWGPPHHGWKFYTGTYWGGGHPVVICMHGR--HYMGPPNAAIYMANIWLMHHFGCDTIIRTGTCGGL-N

SK-VNLGDVIVSDFIVDLSDFRKEPGSIIPRKPQPPAGTTLSSFFSDISGFKMKHSQEENAKE--------VNVHCGPIASSPVLVDDEEFKEQ--LSKA
 . ...|||...| .... ..     .  ..             . |   ..  .   . |||        ..||.|.....   . . . . .  . . 
PDHLKPGDVVIPDDHINH-HHDGTRPLFFYN-----------HYHPDM-WPHYDPELRQLAKEAAERLGLWIPVHRGVYWCTDGFYFETPAEIRLKMWRR

RPDALAGEMEGAAIFSAARHAHHKPEVIVIKAVGD-----WGDGKKDECRGWKDFASHAAATYIHHH-LNDAAP
 . ..  |||.||.. ...|.  .  ...|... |     |.|.  .  .   ..  ..||. ..   . ..  
WGADCV-EMETAAEAQVCHHFGIP--FACICMISDYAAGHWADEPWTH-HEEFEWFMERAAERAARLAVEAFIR