AqueK216

Species: A.queenslandica
Alias: AqueK216
External Links:
Annotation:

Classification

Group: Other
Family: VPS15

Sequence

Name Sequence Type Origin Length Description Download
AqueK216.AA Protein None 636 None Fasta, JSON
AqueK216.kin_dom Protein Kinase Domain None 164 None Fasta, JSON

Protein domain

Protein domains of AqueK216.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK216.AA VPS15 25-302 47 1.2e-128 433.65 In-house 2-296 (296) Show / Hide
Range on Protein: 25-302
Range on HMM: 2-296/296
Sequence Identity: 47% (143 aa)

DFGKPVSLGSTRFMKVARSKYTDGTEVVVKIFPKIDSSVQLQMYEKRLHDINMRLRFIA--NVLPYQNFWDSDKAAFLVRQHVQYNLYDRISTRPYLNNI
.. |  .|||||||||.. |   | ..|||.| | |    |  |  |. .|   |.     |..||| .  .|||| ..||.|  ||||||||||.|..|
HYVK--NLGSTRFMKVCKAKHHEG-YIVVKVFVKHDDTYSLEPYKQRIEEIKKNLMQHPAFNCCPYQKVIETDKAAYMMRQYVKHNLYDRISTRPFLQMI

EKKWIVFQLLKALEGCHEKK-VYHGDLKTENVLLTGWGWVFLTDFASFKPTLLPADNPADYTFFFDTSRRRNCYVAPERFVHASSYSQSSSA-------S
||||| ||.|.|||.|| .. | |||.|.||.|.| | |..|||||.|||. || |||||.||||||||||.|| |||||| .  . | |          
EKKWIAFQTLCALEQCHKQGNVCHGDIKSENILVTSWNWCYLTDFACFKPCYLPEDNPADFTFFFDTSRRRTCYIAPERFVSNTEQDQDSNNGNMRDIHT

DSFQRNKPL------TYEMDIFSLGCVTAELFLDG-QLIFNLSELLDYCQKEFSP--EPLLKKITDKYIKKMVRHMIQFK-ASDRRRPEQYLTMFKGL
||  |. .       | .|||||.||| ||||..| | .|..| |. |. .| .|  | ...|| |  |. .. ||||   .. |  .|.||  ..| 
DSIDRQQNPWLFGELTPAMDIFSAGCVIAELFCEGDQPPFDYSQLCKYRSGEYHPNREQIMEKIQDEHIRNLCHHMIQKDNPMKRMSCEEYLNKWRGF

Kinase AqueK216.AA S_TKc 26-308 17 5.7e-13 13.27 SMART 1-231 (231) Show / Hide
Range on Protein: 26-308
Range on HMM: 1-231/231
Sequence Identity: 17% (51 aa)

FGKPVSLGSTRFMKVARSKYTD-GTEVVVKIFPKIDSSVQLQMYEKRLHDINMRLRFIANVLPYQNFWDSDKAAFLVRQHVQY---NLYDRISTRPY---
. .   .|.  | || . . .. | .| .|| .      .  . | ...    .  .| . . .       .  ..|  ..     .|.|.|  |..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LNNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWGWVFLTDF--ASFKPTLLPADNPADYTFFFDTSRRRNC----YVAPERFVHASSYSQ
   ..  . . .. |...||| ||.... | ||| ||.||.    . ..||  | .                     .  |    |.||| .        
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------------TTFCGTPWYMAPEVL--------

SSSASDSFQRNKPLTY-EMDIFSLGCVTAELFLDGQLIFNLSELLDYCQKEFSPEPLLKKITDKYIKKMVRHMIQFKASDRRRPEQYLTMFKGLVFPEYF
            . .. . |. |.||. .|..  |.  |   ..    .|            ..  | ..|.. |.  ..|    . |..       ..|
------------GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF





Kinase AqueK216.AA Ciliate-E1 30-156 16 9e-12 35.02 In-house 1-143 (202) Show / Hide
Range on Protein: 30-156
Range on HMM: 1-143/202
Sequence Identity: 16% (24 aa)

VSLGSTRFMKVARSKYTDGTEVVVKIFPKIDSSVQL-QMYEKRLHD-INMRLRFIANVLPYQNFWDSDKA--AFLVRQHVQYNLYDRIS-----------
.. ||  ... |... .   .| .||.  .. ..|  . .|..  . | . ...  ... .... ..|..    .. . ....|.| ..           
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

--TRPYLNNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLLT
  .  ...  .|  |.|||...|.  | ....|.|.| .|.| .
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILIN

Kinase AqueK216.AA NuaK 108-155 39 1.3e-11 26.26 In-house 85-132 (252) Show / Hide
Range on Protein: 108-155
Range on HMM: 85-132/252
Sequence Identity: 39% (19 aa)

NLYDRISTRPYLNNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLL
.||| || .  |   | . .  |   |.  ||  .. | ||| ||.||
ELYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENILL

Kinase AqueK216.AA CMGC 99-166 18 1.5e-10 29.98 In-house 131-248 (513) Show / Hide
Range on Protein: 99-166
Range on HMM: 131-248/513
Sequence Identity: 18% (22 aa)

FLVRQHVQYNLYDRISTRP---------YLNNIE------------KKWIV------FQLLKALE--GCHEKK--VYHGDLKTENVLLTGW---------
.||  .....||. |   .         .|.  .            .| ..      .|.|..|.   || ..  . | ||| ||.|..           
YLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMW

-----------GWVFLTDF
           | . . ||
KSEDWNPCQKNGRLKICDF

Kinase AqueK216.AA RAN 125-166 37 1.6e-10 31.38 In-house 152-194 (324) Show / Hide
Range on Protein: 125-166
Range on HMM: 152-194/324
Sequence Identity: 37% (16 aa)

KWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWGW-VFLTDF
| .. |.  |.. ||.. .|| | | ||.|. |  | ..|.|.
KHVFLQICDAINYCHNHGIYHCDIKPENILIDGIDWNIYLCDW

Kinase AqueK216.AA CDK 125-166 34 1.8e-09 26.28 In-house 111-157 (284) Show / Hide
Range on Protein: 125-166
Range on HMM: 111-157/284
Sequence Identity: 34% (16 aa)

KWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWGW-----VFLTDF
|.. .|||..|. ||.... | |||. | |..  |      . ..||
KCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADF

Kinase AqueK216.AA Ciliate-E2 108-166 25 2.6e-09 28.11 In-house 120-200 (365) Show / Hide
Range on Protein: 108-166
Range on HMM: 120-200/365
Sequence Identity: 25% (22 aa)

NLYDRISTR-----------PYLNNIEKKWIVFQLLK---------------ALEGCHEKK-VYHGDLKTENVLLTGWGWVFLTDF
.|.|.|  .            |..  | | |  |.|.               ||| .|.|. . | |.| ||.|.     ....||
DLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDF

Kinase AqueK216.AA NIM1 109-166 34 6.1e-09 22.41 In-house 87-144 (258) Show / Hide
Range on Protein: 109-166
Range on HMM: 87-144/258
Sequence Identity: 34% (20 aa)

LYDRISTRPYLNNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWGWVFLTDF
|| .|...  |  |. | |  |.. |    |.. . | |.| |||..|  . | . ||
LYTHIHQEGKLREIHCKPIFAQIVSAVKHMHSRNIVHRDIKAENVMYTSNNCVKVGDF

Kinase AqueK216.AA CAMK 109-166 20 3.1e-08 21.87 In-house 151-240 (425) Show / Hide
Range on Protein: 109-166
Range on HMM: 151-240/425
Sequence Identity: 20% (18 aa)

LYDRISTRPY---------------LNNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWG----------------W-VFLTDF
|.|.|  ...               ..  | . .. |.. |.. ||.... | ||| ||.||.  .                . . ..||
LFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF

Kinase AqueK216.AA CDK5 125-166 47 3.3e-08 21.52 In-house 101-142 (287) Show / Hide
Range on Protein: 125-166
Range on HMM: 101-142/287
Sequence Identity: 47% (20 aa)

KWIVFQLLKALEGCHEKKVYHGDLKTENVLLTGWGWVFLTDF
| . .|||| |. |||..| | |||  | |    |   | ||
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADF

Kinase AqueK216.AA Pkinase 84-155 25 0.000127 17.43 Pfam 61-141 (293) Show / Hide
Range on Protein: 84-155
Range on HMM: 61-141/293
Sequence Identity: 25% (21 aa)

NVLPYQNFWDSDKAAFLVRQHVQY-----NLYDRIS--TRPYL--NNIEKKWIVFQLLKALEGCHEKKVYHGDLKTENVLL
|.. .  .. ...   .|  ...       |.|.||   .  .     | | .. |.|..|| ||.... | ||| ||.|.
NIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILI

Kinase AqueK216.AA CMGC 224-247 29 0.000624 7.78 In-house 313-343 (513) Show / Hide
Range on Protein: 224-247
Range on HMM: 313-343/513
Sequence Identity: 29% (9 aa)

TYEMDIFSLGCVTAELFLD-------GQLIF
|...|. |.||. ||...        |. .|
TTPIDMWSVGCIFAEMYTGYQSLIFRGKPLF

Kinase AqueK216.AA Pkinase 195-247 20 0.026079 9.25 Pfam 177-212 (293) Show / Hide
Range on Protein: 195-247
Range on HMM: 177-212/293
Sequence Identity: 20% (11 aa)

YVAPERFVHASSYSQSSSASDSFQRNKPLTYEMDIFSLGCVTAELFLDGQLIF
|.|||                    ... ... |..|.||. .|... |...|
YMAPEVIR----------------GGQYYGPKVDMWSCGCILYEMLC-GRPPF