Gene AqueK228 (A.queenslandica)

AqueK228

Species: A.queenslandica
Alias: AqueK228
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: MEKK4

Sequence

Name Sequence Type Origin Length Description Download
AqueK228.AA Protein None 1813 None Fasta, JSON
AqueK228.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of AqueK228.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK228.AA STE11 1547-1803 36 1.1e-100 340.77 In-house 1-303 (303) Show / Hide 
Range on Protein: 1547-1803
Range on HMM: 1-303/303
Sequence Identity: 36% (110 aa)

WRRGRKLGEGQFGVVYECINLDRGEVQAVKMISLKEKS------------HNTVRDILSEVGVFQSINHKNIVHFHGVEIH---DTDLYLFMEYCNQGTL
|..| ..|.|.||.|| |.|.| ||. ||| | ..  .            | ....| .|. ... .|||||| ..|...|   .  .. ||||| .|.|
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

WGAAKQG-----LEERMIRLYTRDLLRAVDVLHDRGIVHRDIKGANIFLSDDSV--KLGDFGLSVQLH-NVNKTAPQEI-----KHQRGTIP--------
.   . .     ..| .|| ||...|...  ||. ||.|||||||||.|  |..  ||.||| ...|  . ..|. ..      |  .||.         
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

YMSPEVVLMQD---MGRPMDIWAVGCVVVEMFTSKRPWIELEDNAMAIMFQLGNKKSPSYP-AEKMN------DEMIDFLDLCFETDPKQRAVASKLLSH
.|.|||.  .     ||. |||..||.|.||.| |.|| ....|.||.||  | .. | .|  |.|       .|  |||..||| ||| |. |. || |
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

SFV
.|.
PFI
Kinase AqueK228.AA MEKK4 1547-1803 46 5.6e-97 328.49 In-house 1-271 (271) Show / Hide 
Range on Protein: 1547-1803
Range on HMM: 1-271/271
Sequence Identity: 46% (128 aa)

WRRGRKLGEGQFGVVYECINLDRGEVQAVKMISLKEKSHNTVRDILSEVGVFQSINHKNIVHFHGVEIHDTDLYLFMEYCNQGTLWGAAKQG--LEERMI
| || . |||||| || |.| | .|| |.| .      | ....|  |   |  | |.| |   |||.|. ..| ||||| ||||    . |  . | ||
WQRGDHIGEGQFGKVYTCMNMDTHEVMAMKEMRFQRNDHKAIKNIADEIKIFEGIKHPNLVRYYGVEVHREEMYIFMEYCSQGTLERVCHLGGNMQEHMI

RLYTRDLLRAVDVLHDRGIVHRDIKGANIFLSD-DSVKLGDFGLSVQLHNVNKTAPQEIKHQRGTIPYMSPEVVL--MQD--------MGRPMDIWAVGC
|.||  ||||| .||  ||||||||.||||| .  ..|||||| || | |  .| | |.    ||  || |||      |         ||  |||..||
RQYTKQLLRAVNYLHQHGIVHRDIKPANIFLDKCTVLKLGDFGCSVKLQNHSQTMPGEFQSTMGTAAYMAPEVYTYTEKDETTGSYSGHGRAADIWSLGC

VVVEMFTSKRPWI---ELEDNAMAIMFQLGNKKSPSYPAEKMNDEMIDFLDLCFETDPKQRAVASKLLSHSFV
||||| | ||||    .  | . .||.  |    |  | .||. |  ||.| |.| |||.|  |..|| |.|.
VVVEMMTGKRPWHGQTQY-DHNFQIMYKVGMGHYPHIP-DKMSPEGKDFFDHCLEHDPKDRWTANELLDHTFC
Kinase AqueK228.AA STE 1547-1803 25 1.5e-85 290.54 In-house 1-359 (359) Show / Hide 
Range on Protein: 1547-1803
Range on HMM: 1-359/359
Sequence Identity: 25% (92 aa)

WRRGRKLGEGQFGVVYECINLD---------------RGEVQAVKMISLKEKS---------------HNTVRDILSEVGVFQSIN--HKNIVHFHGVEI
|.. .|.|.| ||.|| ..| .                ||. |.| ..|....               |. . .|| |. . .  |  |.|||...| ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

HD-------TDLYLFMEYCNQGTLWGAAK------QGLE----------ERMIRLYTRDLLRA-VDVLHDRGIVHRDIKGANIFLSDDSVKLGDFGLSVQ
..       ..|...|||.. |.|    |      ..|           |  |. ..|..|..  . ||. .|.|||||.|||.|    ||| |||.. |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ

LHNVNK------------TAPQEIKHQRGTIPYMSPEVVLM------QDMGRPMDIWAVGCVVVEMFTSKRPWIELEDNAMAIMFQLGN-----------
| . .             |  |. ..  ||  .|.|||..       .. ..  ||| .||...|| | | || .. .  .  |.. ..           
LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCI

--KKSPSYPA------------------EKMNDEMIDFLDLCFETDPKQRAVASKLLS--HSFV
  ...|. |                   .|. .|..||...|.. ||..|. ||.||.  |.|.
VNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK228.AA S_TKc 1547-1803 27 1.7e-82 281.31 SMART 1-231 (231) Show / Hide 
Range on Protein: 1547-1803
Range on HMM: 1-231/231
Sequence Identity: 27% (76 aa)

WRRGRKLGEGQFGVVYECINLDRGEVQAVKMISLKEKSHNTVRDILSEVGVFQSINHKNIVHFHGVEIHDTDLYLFMEYCNQ--GTLWGAAKQG------
.. .||.|.| ||.|| |.. . |.. |.|.|.         ..|..|. . .. .|.|||....|  . ..||..||||..  |.|    |.       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LEERMIRLYTRDLLRAVDVLHDRGIVHRDIKGANIFLSDDSVKLGDFGLSVQLHNVNKTAPQEIKHQRGTIPYMSPEVVLMQDMGR-PMDIWAVGCVV
  . | ..| |.. ...|.. .|..||.|||.| .||.|..  .|..||||. ||           ... ||  ||.|||.     |. . |.|..||..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

VEMFTSKRPWIELEDNAMAIMFQLGNKKSPSYPAEKMNDEMIDFLDLCFETDPKQRAVASKLLS-------HSFV
 ||.. . |.     . .... ..|             .|..||.. |.. ||..|  | ..|        | ..
YEMLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK228.AA Pkinase 1547-1803 25 1.6e-71 248.69 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1547-1803
Range on HMM: 1-293/293
Sequence Identity: 25% (75 aa)

WRRGRKLGEGQFGVVYECINLDRGEVQAVKMISLKEKSHNTVRDILS--EVGVFQSINHKNIVHFHGVEIHDTDLYLFMEYCNQG----TLW----GAAK
...|||.|.| ||.||.|.. . |.. ||| |........  .  .   |. . ...||.||| ....   ....|. ||||. |     |.    . ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QGL--EERMIRLYTRDLLRAVDVLHDRGIVHRDIKGANIFLS-DDSV----KLGDFGLSVQLHNVNKTAPQEIKHQRGTIPYMSPEVVL-MQDMGRPMDI
 ..  .|. .. | . .||... .|..||.|||.| .||... .. .    |..||||. |.     . ... ..  ||..||.|||..  |. |.. |.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDM

WAVGCVVVEMFTSKRPWIEL----EDNAMAIMFQLGNKKSPSYPAEK-------------------MNDEMIDFLDLCFETDPKQRAVASKLLSHSFV
|..||.. ||.. . |. .     ... |..... . .. ..   ..                   ...|..||.. |.. |||.|  |  .| | ..
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase AqueK228.AA STE11-Unclassified 1547-1803 31 1.7e-65 223.92 In-house 1-308 (308) Show / Hide 
Range on Protein: 1547-1803
Range on HMM: 1-308/308
Sequence Identity: 31% (99 aa)

WRRGRKLGEGQFGVVYECINLDRGEVQAVKMISLKEKS------HNT-VRDILSEVGVFQSINHKNIVHFHGVE--IHDTDLYLFMEYCNQGTLWGA-AK
|  |  .|.| || || |.|.. ||. ||| |  . ..      ... .  | .|. | .. ||||||   |.|   | . ...||||.  | .| .  |
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

QG-LEERMIRLYTRDLLRAVDVLHDRGIVHRDIKGANIFL-SDDSVKLGDFGLSV---------------------QLH-NVNK--TAPQEIKHQRGTIP
.| ..|  |. ||...|  .. ||  ||.||||||||| . .|  .|| |||..                      ...  .|.   . ....   ||..
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQ---GTPY

---YMSPEVVLM--QD-MGRPMDIWAVGCVVVEMFTSKRPWIELED-NAMAIMFQLGNKKSPSYPAEKMN-----------DEMIDFLDLCFETDPKQRA
   .|.|||.    |.  .|  |||..||.|.||.| |.||  ... | |....  .. ...    |..            .|  |||..||..||| |.
QPFWMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRP

VASKLLSHSFV
 |. ||.|.| 
TANQLLQHPFI
Kinase AqueK228.AA STE20 1547-1803 29 2.3e-60 206.85 In-house 1-288 (288) Show / Hide 
Range on Protein: 1547-1803
Range on HMM: 1-288/288
Sequence Identity: 29% (85 aa)

WRRGRKLGEGQFGVVYECINLDRGEV----QAVKMISLKEKSH--NTVRDILSEVGVFQSINHKNIVHFHGVEIHD----TDLYLFMEYCNQGTLWGAAK
.   .|.|.| .|.|| ... . ||.     |.|...|....   . ..||. |. . .  .|.|||...|  . |    ..|.. ||||. |.|  . |
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

Q-----------GLEERMIRLYTRDLLRAVDVLHDRGIVHRDIKGANIFLSDD-SVKLGDFGLSVQLHNVNKTAPQEI---KHQRGTIPYMSPEVVLM--
.            ..|  |   .|..|.. | || ..|.|||||..|| |..| .||| |||.. || ....    .    ..  ||  .|.|||..   
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGR-D-TMQFKRNTFVGTPYWMAPEVIQCME

---QDMGRPMDIWAVGCVVVEMFTSKRPWIELEDNAMAIMFQLG--NKKSPSYP---AEKMNDEMIDFLDLCFETDPKQRAVASKLLSHSFV
   .. .   |||..|    || . . |  ..  ..|  ||.    ....|       .|  .|  ||.|.| . ||..|. ||.||.|.|.
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDM--HPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase AqueK228.AA MEKK2 1547-1803 38 1.3e-57 197.74 In-house 1-262 (262) Show / Hide 
Range on Protein: 1547-1803
Range on HMM: 1-262/262
Sequence Identity: 38% (101 aa)

WRRGRKLGEGQFGVVYECINLDRGEVQAVKMISLKEKSHNTVRDILS---EVGVFQSINHKNIVHFHGVEIHDT--DLYLFMEYCNQGTLWGAAKQ--GL
||||. || | ||.|| |   | |   ||| .   ... .| ... .   |. . . . |. || ..|         | .||||   | .    |    |
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGAL

EERMIRLYTRDLLRAVDVLHDRGIVHRDIKGANIFL-SDDSVKLGDFGLSVQLHNVNKTAPQEIKHQRGTIPYMSPEVVLMQDMGRPMDIWAVGCVVVEM
 | . | ||| .|  .  |||  |||||||||||   |   ||||||| |  |  .       .|   ||  .|||||.     ||  |.|..|| ||||
TETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTICMHI-TGMKSVTGTPYWMSPEVINGEGYGRKADVWSIGCTVVEM

FTSKRPWIELEDNAMAIMFQLGNKKSPSYPAEKMNDEMIDFLDLCFETDPKQRAVASKLLSHSFV
 | | || | |  ||| .|..  ..      ... ..  ||| .||    ..|  |  || | ||
LTEKPPWAEYE--AMAAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase AqueK228.AA CAMK 1552-1803 17 1.4e-53 170.7 In-house 1-425 (425) Show / Hide 
Range on Protein: 1552-1803
Range on HMM: 1-425/425
Sequence Identity: 17% (73 aa)

KLGEGQFGVVYECINL-DRG-----------EVQAVKMISLKEKS--------------------------HNTVRDILSEVGVFQS-------INHKNI
.||.|.||.|..||.  . |           .  |.|.|. |  .                           .. . ...|. . ..       ..|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VHFHGVEIH-------------------DTDLYLFM---EYCNQG----TLWGAAKQG-----------------LEERMIRLYTRDLLRAVDVLHDRGI
.... |                      |...|..|   |||  |     |    ..                  ..||  | | | .. ||. .|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKGANIFLSDDS------------------VKLGDFGLSVQLHNVNKTA-------------------PQEIKHQRGTIPYMS-PEVVLMQD----
||||.|  || |.|..                  .|. |||.. ..   ..                      |  | . || .||. |||.. .     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------MGRPMDIWAVGCVVVEMFTSKRPWIEL-------------EDNAMAIMFQLGNKKSPSYPAEKMN--------------------DEMID
           |.. |.|..|..   | . . |. .              .|. .  . . |.   |...  .                      .| .|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FLDLCFETDPKQRAVASKLLSHSFV
..  . ..||..|. ..  |.| ..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase AqueK228.AA Ciliate-E2 1547-1803 18 2.3e-53 181.52 In-house 1-365 (365) Show / Hide 
Range on Protein: 1547-1803
Range on HMM: 1-365/365
Sequence Identity: 18% (71 aa)

WRRGRKLGEGQFGVVYECIN-LDRGEV-----------------QAVKMISLKEKSHNTVRDILSEVGVFQ----------------SINHKNIVHFHGV
    .|.|.|.||.||.| . ... ..                 ...|.. .| ...| .. |..|  ...                ..||.||. .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

EI--HDTDLYLFMEYCNQGTLW-------GAAKQGLE------ERMIRLYTRDLLR---------------AVDVLHDRG-IVHRDIKGANIFLSDDSVK
 .   |. .|| ||||..|.|.          .. .|      |. |. ... .|.               |.  || .. |.|||||  ||..    .|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK

LGDFGLSVQLHNVNK-----TAPQEIKHQR-----------------------GTIPYMSPEVVLMQD---------MGRPMDIWAVGCVVVEMFTSKRP
. ||||| .... |.        ....  .                       || .||.||.. ...          .   |||..|..  || . |.|
IIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WIELEDNAMAIMFQLGNKKSPSY--------------PAEKMNDEMIDFLDL----CFETDPKQRAV-ASKLLSHSFV
.         .  . .. . |..                .|  .|..|..      ... ||..|   ....| | . 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase AqueK228.AA MEKK15 1547-1803 35 5.6e-51 175.67 In-house 1-264 (264) Show / Hide 
Range on Protein: 1547-1803
Range on HMM: 1-264/264
Sequence Identity: 35% (96 aa)

WRRGRKLGEGQFGVVYECINLDRGEVQAVKMISL----KEKSHNTVRDILSEVGVFQSINHKNIVHFHGVEIHDTDLYLFMEYCNQGTLWGAAKQ--GLE
|..|  || | .| || |   . | . ||| . |    |||..   | .  || . ... ||||| . || ..|  . .||..   | .         |.
WKKGNILGKGAYGTVY-CGLTNTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSIINRFGPLD

ERMIRLYTRDLLRAVDVLHDRGIVHRDIKGANIFL-SDDSVKLGDFGLSVQLHNV--NKTAPQEIKHQRGTIPYMSPEVVLMQDMGRPMDIWAVGCVVVE
| .   ||. .|. |  ||.  .|||||||.|. | .   .|| |||    |     |.|  . .|  |||  .| |||.     ||  |||..|| | |
EMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIMETGYGRKSDIWSIGCTVFE

MFTSKRPWIELEDNAMAIMFQLGNK--KSPSYPAEKMNDEMIDFLDLCFETDPKQRAVASKLLSHSFV
| | | || ...   || || .| .    |  |. |  ..  .|  .|   | . |. ||.|| |.|.
MATRKPPWADMD--RMAAMFYIGAHRDPMPQLPV-KFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase AqueK228.AA Ciliate-E2-Unclassified 1547-1803 19 8.6e-51 174.4 In-house 1-352 (352) Show / Hide 
Range on Protein: 1547-1803
Range on HMM: 1-352/352
Sequence Identity: 19% (69 aa)

WRRGRKLGEGQFGVVYECINLDRGEVQAVKMIS----------------------LKEKSHNTVR---DILSEVGVFQSINHKNIVHFHGVEIHDTDLYL
 . ....|.|.||.||.|.. . ....| |...                      ...|... .|   .|. .   .....| .||... ..  .  .|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQ--ILLNHPHPFIVKMFYCFQDKQNIYI

FMEYCNQGTLWGAAK-------------------QGLEERMIR-----LYTRDLLRAVDVLHDRG-IVHRDIKGANIFLSDD----SVKLGDFGLSVQLH
 ||||..|.||   |                   . ..|. ..      |.. .| . . ||  . |.|||||  ||.....     .|. |||.| .. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

NVNKTA-----------PQEIKHQRGTIPYM----SPEVVLMQDMGRP----MDIWAVGCVVVEMFTSKRPWIELEDNA----------------MAIMF
. |.             .|..... ||. ||    .|||   |  . .     |||..|..  || . ..|     ..                 .   .
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

QLGNKKSPSYPA----EKMNDEMIDFLD----LCFETDPKQRAVASKLLSHSFV
. .| . |..|      . ..| .||.      ... .|..|  ....| | . 
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase AqueK228.AA TyrKc 1547-1802 22 3.8e-16 38.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 1547-1802
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

WRRGRKLGEGQFGVVYECINLDRGEVQAVKMISLKEKSHNTVRDILSEVGVFQSI--NHKNIVHFHGVEIHD-------TDLYLFMEYCNQGTLWGA--A
 . |.|||||.||.||...     .  ||||.         ..|...|  .  ..  .|.||| ..|| ...         |.. |||.  | |     .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KQG-LEERMIRLYTRDLLRAVDVLHDRGIVHRDIKGANIFLSDDS-VKLGDFGLSVQLHNV-------NKTAPQEIKHQR--GTIPYMSPEVVLMQDMGR
... |  .    .  .  .  . ||.....|||.   |. ....  || .|||||  ...            ..| |. .    |  |.||.  .  .  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

PM-DIWAVGCVVVEMFTS-KRPWIE-LE--DNAMAIMFQLGNKKSPSYPAE-------KMNDEMIDFLDLCFETDPKQRAVASKLLSHSF
.  |.|. | .  |.||  . |. .  .   ..  .. .. . . .  |..        . ||| .    | . ||..|   | .  . |
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase AqueK228.AA Pkinase_Tyr 1547-1631 31 4.4e-15 51.72 Pfam 96-189 (270) Show / Hide 
Range on Protein: 1547-1631
Range on HMM: 96-189/270
Sequence Identity: 31% (31 aa)

WRRGRKLGEGQFGVVYECINL-----DRGEVQAVKMISLKEKSHNT---VRDILSEVGVFQSI-NHKNIVHFHGVEI-HDTD--LYLFMEYCNQGTL
 . |.|||||.||.||...       .. .| ||||.  ||...      .| ..|. .  .. .|.||| ..|| . ..    .|. |||.  | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPV-AVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase AqueK228.AA Pkinase_Tyr 1658-1688 34 0.000115 16.42 Pfam 127-158 (270) Show / Hide 
Range on Protein: 1658-1688
Range on HMM: 127-158/270
Sequence Identity: 34% (11 aa)

LHDRGIVHRDIKGANIFLS-DDSVKLGDFGLS
|......|||.   |. .. .  || .||||.
LESKNCIHRDLAARNCLVTENNVVKICDFGLA