Gene AqueK451 (A.queenslandica)
AqueK451
Species: A.queenslandica
Alias: AqueK451
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK451.AA | Protein | None | 1891 | None | Fasta, JSON |
| AqueK451.kin_dom | Protein Kinase Domain | None | 236 | None | Fasta, JSON |
Protein domains of AqueK451.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| AAA | AqueK451.AA | AAA | 207-330 | 18 | 1.2e-15 | 58.67 | Pfam | 1-150 (150) | Show / Hide |
Range on Protein: 207-330 Range on HMM: 1-150/150 Sequence Identity: 18% (29 aa) IIIHGLPGTGKSLIAEAISSNVPL-----VNIKIINSSDLLRTN--------------ALQLIELTLQQL-ESGS----IGILIVNDIDKVCLNN----- ....| |||||...|.|. . . ... |. ..|. ..|. .... .. . |... .||..| . MLLYGPPGTGKTMLAKAVANE--CQGELHAPFFEISGPELV-SKDEYEIGHRRTYVGESEKRIRQLFEKAQKKHAEWKKPCIIFIDEIDAICPKRSEHEE -QLIVSALIKHFETVAKLPSLRHSVVLATTNN-LSSVHIELRCPGRFDKEIEMHP . .|..|.. .. . . .. .|.|.||. .. || |||||..|. RRRVVNQLLTQMDGFQNN--NGKVIVIAATNRPPDMIDPALRRPGRFDRHIYFPL |
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| AAA | AqueK451.AA | AAA | 203-332 | 17 | 7e-09 | 36.76 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 203-332 Range on HMM: 1-92/92 Sequence Identity: 17% (23 aa) FPRGIIIHGLPGTGKSLIAEAISSNVPLVNIKIINSSDLLRTNALQLIELTLQQLESGSIGILIVNDIDKVCLNNQLIVSALIKHFETVAKLPSLRHSVV .. |.|.| ||.||. .| || . . ...|. . | |.. .. ... ..|.. .|.. | PGEHILIVGPPGCGKTTLARAIARYLQP-GVIYIDCD------GGQRIRQAFARARK---DVLFIDEITSMLD------------------------VTV LATTNNLSSVHIELRCPGRFDKEIEMHPPQ ..||... . ... |||..|.. .| ICTTHDPDPMALRH----RFDRRIYIRRPD |
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| AAA_5 | AqueK451.AA | AAA_5 | 206-226 | 28 | 0.002596 | 11.2 | Pfam | 1-21 (174) | Show / Hide |
Range on Protein: 206-226 Range on HMM: 1-21/174 Sequence Identity: 28% (6 aa) GIIIHGLPGTGKSLIAEAISS .... | |||||..... ... HVCLIGPPGTGKTWLWMRLAH |
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| AAA | AqueK451.AA | AAA | 463-594 | 45 | 2.4e-65 | 228.21 | Pfam | 1-150 (150) | Show / Hide |
Range on Protein: 463-594 Range on HMM: 1-150/150 Sequence Identity: 45% (69 aa) ILLYGPPGCSKTMIVRALATET-C---FNFISIKGPEIFNK----------WVGDSEKAIRKVFSRA-RAAA----PSIVFFDEIDSIATHRQSGDGSKV .|||||||. |||...|.|.|. ..|..|.|||...| .||.||| ||..|..| .. | |.|.|.||||.|.. | ... . MLLYGPPGTGKTMLAKAVANECQGELHAPFFEISGPELVSKDEYEIGHRRTYVGESEKRIRQLFEKAQKKHAEWKKPCIIFIDEIDAICPKR---SEHEE GDRILTQLLTEMDGIESLKG-VLIIAATNR-PDIIDKALLRSGRFDKKIYVPL ..|.. ||||.||| .. .| |..|||||| ||.||.||.| ||||..||.|| RRRVVNQLLTQMDGFQNNNGKVIVIAATNRPPDMIDPALRRPGRFDRHIYFPL |
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| AAA | AqueK451.AA | AAA | 459-596 | 26 | 3.4e-21 | 77.65 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 459-596
Range on HMM: 1-92/92
Sequence Identity: 26% (37 aa)
AVKGILLYGPPGCSKTMIVRALATETCFNFISIKGPEIFNKWVGDSEKAIRKVFSRARAAAPSIVFFDEIDSIATHRQSGDGSKVGDRILTQLLTEMDGI
. . ||..||||| || ..||.| . .| | .. ... ||..| |||. ...|.|||.|..
PGEHILIVGPPGCGKTTLARAIARYLQPGVIYIDCD---------GGQRIRQAFARARK---DVLFIDEITSMLD-------------------------
ESLKGVLIIAATNRPDIIDKALLRSGRFDKKIYVPLPT
| .|..|. ..|...||. |||..||...|.
-----VTVICTTH---DPDPMALRH-RFDRRIYIRRPD
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| AAA_5 | AqueK451.AA | AAA_5 | 462-481 | 45 | 4e-05 | 16.89 | Pfam | 1-20 (174) | Show / Hide |
Range on Protein: 462-481 Range on HMM: 1-20/174 Sequence Identity: 45% (9 aa) GILLYGPPGCSKTMIVRALA ...| ||||. ||.... || HVCLIGPPGTGKTWLWMRLA |
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| AAA_5 | AqueK451.AA | AAA_5 | 563-586 | 31 | 3.221373 | 1.48 | Pfam | 148-174 (174) | Show / Hide |
Range on Protein: 563-586 Range on HMM: 148-174/174 Sequence Identity: 31% (9 aa) GVLIIAATNRPD-----IIDKALLRSGRF .. .||..|..| ...||.| || NFRVIATMNPRDRRGVNWMSPALRR--RF |
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| PUB | AqueK451.AA | PUB | 723-797 | 24 | 3.5e-08 | 31.28 | Pfam | 1-90 (90) | Show / Hide |
Range on Protein: 723-797 Range on HMM: 1-90/90 Sequence Identity: 24% (22 aa) YSEEDFLETTRVLLAILHNVIHDPANEKNRRLRAASKFIN-----KPG-ITDLLRSVGFVKK----DSYLFLD------NLEDNLKQLRSL . | |.| ..|. .| |.| .| .|| ||.| .| . .| ..|...|||.. ...|.. .| . .. . .| NDKEHFKECLETLFKYLRNIIKHPNEEKYRRIRMCNKTFQEKILSYEGFAVEFLECCGFVEVEDEGEEFLVWPFEDSMVDL-QLQCAIEYL |
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| PUG | AqueK451.AA | PUG | 730-785 | 27 | 0.000589 | 14.28 | SMART | 1-66 (66) | Show / Hide |
Range on Protein: 730-785 Range on HMM: 1-66/66 Sequence Identity: 27% (18 aa) ETTRVLLAILHNVIHDPANEKNRRLR-----AASKFINKPGITDLLRSVGFVKK-----DSYLFLD |. |.|| .. |..| | .|| |..| |. . || ......||.. . |.|. ESVRDLLRYMRNIYHHPREEKFRKIRMENKAFKEKMGQVPGGFECYFTCGFPDLMIHAWEHYFFCK |
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| Kinase | AqueK451.AA | TK | 821-1056 | 17 | 1.8e-65 | 218.14 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 821-1056
Range on HMM: 1-486/486
Sequence Identity: 17% (84 aa)
LHFIKIIGSSKYG---DVIQGTIGG---------------------------QDVAIKTLNPENRLTDKKSFR-------------QELDILSQLT----
....| .|. .| .| .|. | ..||.|.| ... ... | .|. .....
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
-HPQIVRLIGATLLS------------EPTSLIIELLPH-----SMLHLLHQGE----------------------------------------------
|| ||||.|. . . || .. |. || | .. |..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
-------------------------------LCDVEIFRYARQVAMGMEYIHSK----------------NILHFSAEG----------EVKISDFSTSR
|. . ...|.| ||||.||| |.| .. .||.|| ||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
Q----EGVPLTN--------------------------------RHLINVRWSPPEVFN---------DGTFSKESDVWSYGILLYEFVTSGSVPYAN-F
| . . . . .|| .||..| .|.|. .|||||.|.|..| .| | .||.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM
SN---------NQVQTKVTEG--------------YRLLQPPCCL--------------DEFYSVMSKCWSVSPVDRPGFTSIVSLL
|| .| ....| .|. ||| | .|.| .| .||. | ||| |. ... |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| TyrKc | AqueK451.AA | TyrKc | 821-1056 | 31 | 2.9e-65 | 224.06 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 821-1056 Range on HMM: 1-280/280 Sequence Identity: 31% (89 aa) LHFIKIIGSSKYGDVIQGTIGGQDVAIKTLNPENRLTDKKSFRQELDILSQL--THPQIVRLIGATLLS-------EPTSLIIELLPH-SMLHLLHQGE- ....|..|. .| | .|| ..||.|.|... .. |..|. |...| || ||||.|. . . || .. |. || . .. |. . ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP -LCDVEIFRYARQVAMGMEYIHSKNILH---------FSAEGEVKISDFSTSRQEGVP--------LT------NRH-LINVRWSPPEVFNDGTFSKESD || . .. |.| ||||.||||. | .... |||||| || . ... .. .|| .||..|.|.|. .|| KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD VWSYGILLYEFVTSGSVPYAN-----FSNNQVQTKVTEGYRLLQPPC--------CLDEFYSVMSKCWSVSPVDRPGFTSIVSLL |||.|....| | | || . || .| .| .|||. ||| | || |..|..|| | ||| |. |.... VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | AqueK451.AA | TK-Unique | 821-1056 | 27 | 4e-64 | 219.36 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 821-1056
Range on HMM: 1-294/294
Sequence Identity: 27% (81 aa)
LHFIKIIGSSKYGDVIQGTIGG--------QDVAIKTLNPENRLTDKKSFRQELDILSQLT-HPQIVRLIGATLLS-EPTSLIIELLPHS-MLHLLHQGE
| . ..||. ..| |. |.. | . ||.|.|. ....|||. | .|. ....|. || ||...|.. | ||. .|.| .| . .|.|..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR
---------------------------LCDVEIFRYARQVAMGMEYIHS--KNILH---------FSAEGEVKISDFSTSR-----QEGVPLTNRHLINV
. ...| |.|.||||..| |.| | .. ...||.|| .| .. . . .. | .
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI
RWSPPEVFN--DGTF-SKESDVWSYGILLYEFVTSGSVPYANFSNNQVQTKVTEGYRLLQPPCC-LDEFYSVMSKCWSVSPVDRPGFTSIVSLL
|| .||.. .|.. . .|||||.|.|..| .| |. || . .. ........|||..||. | .|.|..|. ||. .| .|| |..|.. |
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
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| Kinase | AqueK451.AA | UTK | 821-1056 | 23 | 6.2e-48 | 162.07 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 821-1056 Range on HMM: 1-296/296 Sequence Identity: 23% (70 aa) LHFIKIIGSSKYGDVIQGTI-------GGQDVAIKTLNPENRLTDKKS----FRQELD---ILSQLT-HPQIVRLIGATLLSEPTSLIIELLP----HSM ... . .|. .|.| .. . .|||.|..... .... |. | ...|. ||...||.| . .||. ...|. . |. VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY LHLLHQGELCDVEIFR------YARQVAMGMEYIHSK----------NILHFSAE------GEVKISDFS---TSRQEG-------------VPLTNRHL | .. . .... .|...| ||.|.||. |.|... . .||.|| ||. . . ... LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR INVRWSPPEVFNDG-TFSKESDVWSYGILLYEFVTSGSVPYANFSNNQVQTKVTEG--YRLLQPPCCLDEFYSVMSKCWSVSPVDRPGFTSIVSLL . .|| ||..... .|. |||||.|....| .| |..||.. || || . |..| ||. .|. | .. | .| .|| .| .|| | .|. . WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM |
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| Kinase | AqueK451.AA | Fer | 821-1057 | 25 | 4.6e-44 | 147.98 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 821-1057 Range on HMM: 1-283/283 Sequence Identity: 25% (73 aa) LHFIKIIGSSKYGDVIQG---------TIGGQ---DVAIKTLNPENRLTD-KKSFRQELDILSQ-LTHPQIVRLIGATLLSEPTSLIIELLPH-SMLHLL ...|..|. .|.| .| . . .|. |... | .. .| | .| |. . . || .|...| . .| ...|. .. | . | VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL HQ-GE--LCDVEIFRYARQVAMGMEYIHSKNILH---------FSAEGEVK---ISDFSTSRQE---GVPLTNR---HLINVRWSPPEVFNDGTFSKESD .. . | |..|.. |.| ||||.||||..| .... .| |||| |||. |. . . ...|| .||....|..|...| KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD VWSYGILLYEFVTSGSVPYAN----FSNNQV-----QTKVTEGYRLLQPPCCLDEFYSVMS-KCWSVSPVDRPGFTSIVSLLL |||.|....|. | | ||.. . ...| . ....||.. |. . .|....| .|| . | ||| ...|. | VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK |
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| Kinase | AqueK451.AA | Frk | 821-1060 | 32 | 3.5e-42 | 143.82 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 821-1060 Range on HMM: 1-260/260 Sequence Identity: 32% (84 aa) LHFIKIIGSSKYGDVIQGTIGGQ-DVAIKTLNPENRLTDKKSFRQELDILSQLTHPQIVRLIGATLLSEPTSLIIELLPHS-MLHLLH----QGELCDVE ...|. .|| ..|.| | . ||.||| | | . | .| |. .| ||....| . || .| ||. | ... | .|. | .. IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGT--MDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQ IF-RYARQVAMGMEYIHSKNILH---------FSAEGEVKISDFSTSR---QEGV-PLTNRHLIN--VRWSPPEVFNDGTFSKESDVWSYGILLYEFVTS . | ||| || |. |.| .| . .|| || | .. || . ..| || | |. |||||.||||.| .| QLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITY GSVPYANFSNNQVQTKVTEGYRLLQPPCCLDEFYSVMSKCWSVSPVDRPGFTSIVSLLLNPM | .||. | .| . | .|||. ||| | ..|..| .|| . | || | . | . . GRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF |
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| Kinase | AqueK451.AA | TKL | 827-1056 | 21 | 7.8e-42 | 145.31 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 827-1056
Range on HMM: 1-364/364
Sequence Identity: 21% (80 aa)
IGSSKYGDVIQGTIGG----------QDVAIKTLNPEN-RLTDK-------------------------KSFRQELDILSQLTHPQIVRLIGATLLSEP-
||| .| | .|. | .|||.|... .| ...| . ...|. ..|.| || ||...|. . ...
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------TSLIIELLPHSM-LHLLHQGELCDVEI-FRYARQVAMGMEYIHS------------------KNILHFS-------------AEGEVK
.. |. |. ||.|| . .| |...| ||.| || |||| .. |.. .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK
ISDFSTSR---------------------QEGVPLTNRHLI-NVRWSPPEVFNDG----------------TFSKESDVWSYGILLYEFVTSGSVPYANF
|.|| .|| | |. . . . || .|||... ..|. .||.|.||.|.| .| ||...
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQ-NNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-PYYDY
SNNQVQ---------TKVT-EGYRLLQP----------PC--CLDEFYSVMSKCWSVSPVDRPGFTSIVSLL
..... .| .|.|.. | || |.... . | .||. | .|| |. |.. |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | AqueK451.AA | Pkinase_Tyr | 943-1056 | 36 | 1e-41 | 141.94 | Pfam | 150-270 (270) | Show / Hide |
Range on Protein: 943-1056 Range on HMM: 150-270/270 Sequence Identity: 36% (45 aa) VKISDFSTSRQE-----G-VPLTNRHLINVRWSPPEVFNDGTFSKESDVWSYGILLYEFVTSGSVP-YANFSNNQVQTKV-TEGYRLLQPPCCLDEFYSV |||.|| .| . .. . ..| .||..|.| |. .|||||.|.|..| .| | | |.. ||..| .. .|||. .|. | || |.. VKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDL MSKCWSVSPVDRPGFTSIVSLL | .|| | ||| |. |.. | MKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | AqueK451.AA | RTKD | 964-1058 | 36 | 9.5e-36 | 118.9 | In-house | 168-262 (262) | Show / Hide |
Range on Protein: 964-1058 Range on HMM: 168-262/262 Sequence Identity: 36% (35 aa) INVRWSPPEVFNDGTFSKESDVWSYGILLYEFVTSGSVPYANFSNNQVQTKVTEGYRLLQPPCCLDEFYSVMSKCWSVSPVDRPGFTSIVSLLLN | |||..||| . ||. ||||| ....|| | . .||. .| .| | .|||| .| | . . .| ||. | .||... .| . . IPVRWCAPEVLEEHKFSQASDVWSWAVFVYEIWTQAQLPYRDMHNQKVWHYVIQGYRLTRPMQCPRDIWALMMDCWAEDPKERPRMCQVVDQMTK |
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| Kinase | AqueK451.AA | Src | 966-1056 | 44 | 3.4e-33 | 110.11 | In-house | 164-255 (255) | Show / Hide |
Range on Protein: 966-1056 Range on HMM: 164-255/255 Sequence Identity: 44% (41 aa) VRWSPPEVFNDGTFSKESDVWSYGILLYEFVTSGSVPYANFSNNQVQTKVTEGYRLLQPPCCLDEFYS-VMSKCWSVSPVDRPGFTSIVSLL ..| || .| |.|. |||||.||||.| || | ||| .| .| ..| |||. .|. | ||.| .| .|| .| .|| | . . | IKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
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| Kinase | AqueK451.AA | Tec | 966-1058 | 38 | 5.7e-33 | 112.56 | In-house | 162-254 (254) | Show / Hide |
Range on Protein: 966-1058 Range on HMM: 162-254/254 Sequence Identity: 38% (36 aa) VRWSPPEVFNDGTFSKESDVWSYGILLYEFVTSGSVPYANFSNNQVQTKVTEGYRLLQPPCCLDEFYSVMSKCWSVSPVDRPGFTSIVSLLLN |.|.|||||. .| ||||..|.| | . | .|| |.|| .| ..|..|.|| .| | .. | .| .||. .| .|| | . ... VKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE |
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| Kinase | AqueK451.AA | Pkinase_Tyr | 821-936 | 30 | 2.6e-29 | 99.89 | Pfam | 1-134 (270) | Show / Hide |
Range on Protein: 821-936
Range on HMM: 1-134/270
Sequence Identity: 30% (41 aa)
LHFIKIIGSSKYGDVIQGTIG------GQDVAIKTLNPENRLTD--KKSFRQELDILSQL-THPQIVRLIGATL-LSEP--TSLIIELLPH-SMLHLLHQ
..|.| .|. .|.| .|| ...||.|.|.. . ...| .|. |..|| || ||||.|. . .|| .. |. || ..|. |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK
G-----ELCDVEIFRYARQVAMGMEYIHSKNILH
|. .. ...|.|.|||| .|||. |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH
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| Kinase | AqueK451.AA | S_TKc | 821-1061 | 20 | 1.6e-25 | 92.07 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 821-1061 Range on HMM: 1-231/231 Sequence Identity: 20% (54 aa) LHFIKIIGSSKYGDVIQGTIGG--QDVAIKTLNPENRLTDKKSFRQELDILSQLTHPQIVRLIGATLLSEPTSLIIELLPH---SMLHLLHQGE------ .....||. .| | ... . . |||| .. ...|.|..||.. || ||.|... . .. |.... ........ YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -LCDVEIFRYARQVAMGMEYIHSKNILH---------FSAEGEVKISDFSTSRQEGVPLTNRHLINVRWSPPEVFNDGTFSK-ESDVWSYGILLYEFVTS . .. .|..|.. ..||.||..|.| .. ..||.|| .|| . . .|||. ..| ..|.|| |..|||... PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC- GSVPYANFSNNQVQTKVTEGYRLLQPPCCLDEFYSVMSKCWSVSPVDRPGFTSIVS----LLLNPME | |. . |. |. .|. . ..||. . | .||. . . | GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | AqueK451.AA | TKL-Unique | 938-1056 | 29 | 1.1e-22 | 76.87 | In-house | 151-290 (290) | Show / Hide |
Range on Protein: 938-1056 Range on HMM: 151-290/290 Sequence Identity: 29% (41 aa) SAEGEVKISDFSTSRQEGVP---LTNRH--------LINVRWSPPEVFND--GTFSKESDVWSYGILLYEFVTSGSV------PYANFSNNQVQTKVTE- .|| .||.||..|. .|.| . . ||..|||... ..|. |||.|.|| |.| .| . . || ... .|. .|.. IAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIAT-RKITKTYKKPYQGMDQEQWCEMVHYM --GYRLLQPPCCLDEFYSVMSKCWSVSPVDRPGFTSIVSLL .||. |. | |. . .|| |..|| |..|.. | EENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL |
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| Kinase | AqueK451.AA | TKL-Unique | 823-937 | 26 | 2.7e-19 | 64.83 | In-house | 1-136 (290) | Show / Hide |
Range on Protein: 823-937 Range on HMM: 1-136/290 Sequence Identity: 26% (36 aa) FIKIIGSSKYGDVIQGTIGGQDVAIKTLNP--ENRLTDKKSFRQELDILSQLT-HPQIVRLIGATL----LSEPTSLIIELLPHSMLH-LLHQ------- |.. ||...|| |..|. | .||||...| . ... .. |. |. ... | ||.||...|.. ... | .|.. |. .||| FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN -GELCDV---EIFRYARQVAMGMEYIHSKN--ILHF . |. . . |...| ||.|.|... |.|. NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHR |
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| Kinase | AqueK451.AA | Pkinase | 821-936 | 25 | 4.3e-17 | 61.53 | Pfam | 1-131 (293) | Show / Hide |
Range on Protein: 821-936 Range on HMM: 1-131/293 Sequence Identity: 25% (33 aa) LHFIKIIGSSKYGDVIQGT-IGGQD-VAIKTLNPENRLTDKK--SFR-QELDILSQLTHPQIVRLIGATLLSEPTSLIIELLPH-----SMLHLLH---Q .|....||| .| | ... .| .. ||.|... ... .|. .| .|. |. | || ||||... . .. |.... . .... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GEL--CDVEIFRYARQVAMGMEYIHSKNILH | . . |. .|..|.. |.||.||..|.| GCFYFSEWECKFYMYQILRGLEYCHSMGIIH |
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| Kinase | AqueK451.AA | Src | 821-936 | 31 | 1.1e-13 | 42.87 | In-house | 1-120 (255) | Show / Hide |
Range on Protein: 821-936
Range on HMM: 1-120/255
Sequence Identity: 31% (38 aa)
LHFIKIIGSSKYGDVIQGTIGG-QDVAIKTLNPENRLTDKKSFRQELDILSQLTHPQIVRLIGATLLSEPTSLIIELLPH-SMLHLLH-QGELCDVEIFR
..... .|. ..|.| .|. | .||.||| | . . . | || |. .| |. .|.| || . |. | | | |. .|| ... .
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQ
Y---ARQVAMGMEYIHSKNILH
| ||| ||.|. |.|. |
LIDMAAQVAEGMAYLESMNYIH
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| Kinase | AqueK451.AA | Pkinase | 967-1056 | 18 | 1.6e-08 | 31.26 | Pfam | 176-293 (293) | Show / Hide |
Range on Protein: 967-1056 Range on HMM: 176-293/293 Sequence Identity: 18% (22 aa) RWSPPEVFN-DGTFSKESDVWSYGILLYEFVTSGSVPYANF----SNNQVQTKVTEGYRLLQPPC---CL-------------------DEFYSVMSKCW .. .||| . . ....|.||.|..|||... | |. . ...| | . ... | .. | .|. .....|. WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL SVSPVDRPGFTSIVSL--L . | .||... |. . CKDPKKRPTAEQILQHPWF |
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| Kinase | AqueK451.AA | RTKD | 868-936 | 36 | 3e-06 | 17.15 | In-house | 55-126 (262) | Show / Hide |
Range on Protein: 868-936 Range on HMM: 55-126/262 Sequence Identity: 36% (26 aa) ILSQLTHPQIVRLIGATLLSEPTSLIIELLPHSML--HLLHQGELCDVEI-FRYARQVAMGMEYIHSKNILH .. |. |. |||| | ..| .. | | | | ||. | || || |||| .|.| . ..| FMAQFNHDNIVRLHGVVTTNQPHIMVMEYCEHGSLQAYLRENGEDMDNQHRFRMARDVAMGLAYLHFRGCCH |
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| Kinase | AqueK451.AA | Tec | 821-936 | 27 | 0.001046 | 8.92 | In-house | 1-120 (254) | Show / Hide |
Range on Protein: 821-936
Range on HMM: 1-120/254
Sequence Identity: 27% (34 aa)
LHFIKIIGSSKYGDVIQGTIGGQ-DVAIKTLNPENRLTDKKSFRQELDILSQLTHPQIVRLIGATLLSEPTSLIIELLPH-SMLHLL--HQGELCDVE--
| |.| .|| .| | | .| |||||... | | .| . |.||. |.| | .. | .. | . | . | | |....
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIK-EGSMSEED-FIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAI
IFRYARQVAMGMEYIHSKNILH
.| ||.| ... .|
LLEMCQDVCEGMAYLERHCFIH
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| PH | AqueK451.AA | PH | 1224-1332 | 16 | 1.2e-11 | 44.62 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 1224-1332 Range on HMM: 1-92/92 Sequence Identity: 16% (18 aa) YKTKGYLVKSECQPSNNSPRGGGGGGSAWQRYWCIVDGSSLLCYLDEEDEGIKQFEIFLDFRSAIVSLTTDKKNEYIKVEMTNNDVYLFNTIDKLDTLRW . .|.| | . . . |...|... .. |..| |. ... | |. .. ... |.. .... . ....|.| . . . .| VIKEGWLHKKG-------------KRKSWKKRWFVLFNNCLYYYKDDK--YRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDW IEAIEAATR ..||..| | MQAIQSACR |
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| PH | AqueK451.AA | PH | 1224-1334 | 14 | 5.9e-11 | 43.64 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 1224-1334 Range on HMM: 1-82/82 Sequence Identity: 14% (16 aa) YKTKGYLVKSECQPSNNSPRGGGGGGSAWQRYWCIVDGSSLLCYLDEEDEGIKQFEIFLDFRSAIVSLTTDKKNEYIKVEMTNNDVYLFNTIDKLDTLRW .|.| | . . |...|.......|..| |. .. .|.|. .. . .... . .. .|.| . .. . .| VIKEGWLYKKS--------------K-RWKKRWFVLFNDCLYYYKDK----KPKGSIPLSDC-TVRE-P------CFEIHH-DR-TYYFQCESEEEMQEW IEAIEAATRQE ..||..|... MQAIQKAIHNN |
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| PH | AqueK451.AA | PH | 1348-1467 | 12 | 0.030131 | 11.42 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 1348-1467 Range on HMM: 1-82/82 Sequence Identity: 12% (15 aa) VVFAGFLTCSYYPSVSTNDPVTSVASIRPGEGLSDVPFSYGKLWCVLKSSGLIQCMVDSKPVDIVHIIKNMNKINVYRNDGGECIIKMTNSNSDDLIMIA |. |.|. .. | |.||.. . . . |. . ..| ..... |.. . .. .. . ... . VIKEGWLYKKS-------------------------K-RWKKRWFVLFN-DCLYYYKDK---KPKGSI-PLSDCTVRE-P----CFEIHH-DR-TYYFQC DSASEHYDWVLNIENILLKN .|..| .|. |.. . .| ESEEEMQEWMQAIQKAIHNN |
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| PH | AqueK451.AA | PH | 1389-1465 | 17 | 0.193862 | 7.84 | Pfam | 18-92 (92) | Show / Hide |
Range on Protein: 1389-1465 Range on HMM: 18-92/92 Sequence Identity: 17% (14 aa) KLWCVLKSSGLIQCMVDSKPVDIVHIIKNMNKINVYRNDG--GECIIKMTNSNSDDLIMIADSASEHYDWVLNIENILL | |.||.. . . . |.| . ..| ......|.. . ........ . . .. |.|. | ||. |. .. KRWFVLFN-NCLYYYKDDK-YRPKGSI-PLSDCQVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR |
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| WW | AqueK451.AA | WW | 1812-1839 | 32 | 0.001036 | 15.6 | Pfam | 1-27 (30) | Show / Hide |
Range on Protein: 1812-1839 Range on HMM: 1-27/30 Sequence Identity: 32% (9 aa) LPVGWERGYSQKSKRHFYFNADLGISKW || |||. .. ..| .|.| . . | LPPGWEEHWD-PDGRPYYWNHNTKTTQW |
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| WW | AqueK451.AA | WW | 1811-1844 | 26 | 0.025642 | 7.35 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 1811-1844 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) SLPVGWERGYSQKSKRHFYFNADLGISKWNYEEV .|| |||. ......| .|.|.. . . | . PLPPGWEEHWDPDYGRPYYYNHNTKETQWEKPRW |
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| WW | AqueK451.AA | WW | 1858-1884 | 33 | 7.9e-07 | 25.59 | Pfam | 1-27 (30) | Show / Hide |
Range on Protein: 1858-1884 Range on HMM: 1-27/30 Sequence Identity: 33% (9 aa) PGNGWHSVNTDDGKVYYYNEVSRKTTW ||. . ..||..||.| ...|.| LPPGWEEHWDPDGRPYYWNHNTKTTQW |
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| WW | AqueK451.AA | WW | 1857-1889 | 29 | 0.000142 | 22.44 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 1857-1889 Range on HMM: 1-34/34 Sequence Identity: 29% (10 aa) KPGNGWHSVNTDD-GKVYYYNEVSRKTTWNIQDT . ||. . . | |..|||| ....|.| . PLPPGWEEHWDPDYGRPYYYNHNTKETQWEKPRW |
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