Gene CDKB_b (S.moellendorffii)

CDKB_b

Species: S.moellendorffii
Alias: CDKB_b
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDKB

Sequence

Name Sequence Type Origin Length Description Download
CDKB_b.AA Protein None 316 None Fasta, JSON
CDKB_b.NA RNA None 951 None Fasta, JSON
CDKB_b.kin_dom Protein Kinase Domain None 305 None Fasta, JSON

Protein domain

Protein domains of CDKB_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CDKB_b.AA CDC2 4-217 47 2.2e-109 337.43 In-house 1-190 (301) Show / Hide 
Range on Protein: 4-217
Range on HMM: 1-190/301
Sequence Identity: 47% (105 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEG--VPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYID-LFG
| |.||.||||||.|||.... ....||||| ||| |.||  |||||.|| |.|. | .   .|.|  | |        ||.|||.|| ||||| | ...
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-----NKLYMVFEYLDMDLKKYMDMSIP

RGNTGRPIPPKIIQVFVDSSGFVTGFLTCVICCQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYT--HEIVTLWY
 .                          ...  .|.|||...||..||....|||||||||.|.|| || .|||| ||.|||..|.. ||  ||.|||||
KN-----------------------KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDK-KGNIKIADFGLARAFGIPIRTYTTEHEVVTLWY

RAPEVLLGATHYSIPVDIW
||||.|||. .||.|||.|
RAPEILLGCKRYSTPVDMW
Kinase CDKB_b.AA CDK 4-217 42 5.4e-105 336.89 In-house 1-206 (284) Show / Hide 
Range on Protein: 4-217
Range on HMM: 1-206/284
Sequence Identity: 42% (104 aa)

YVKLEKVGEGTYGKVYKAREKNSG-----RLVALKKTRLEM-----EEEGVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKG-------KPMLYLVFE
| ||||.||||||.||||| |..|     ..||||| |.|      |.||.|.||.||.|||. |    ..|.|. | | ...        .  ||.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

FLDTDLKKYIDLFGRGNTGRPIPPKIIQVFVDSSGFVTGFLTCVICCQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGI-----LKIADLGLGRA
..|.|||||.|                                   ....|.|| .|...|||...|||||||||.|... .|.     ||||| || ||
YMDHDLKKYMD-----------------------------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINN-NGEVKCGRLKIADFGLARA

FTV------PLKSYTHEIVTLWYRAPEVLLGATHYS--IPVDIW
| .      |.. ||||.|||||||||.|||..|||   |.|.|
FGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMW
Kinase CDKB_b.AA CMGC 4-217 25 1.3e-82 271.09 In-house 1-319 (513) Show / Hide 
Range on Protein: 4-217
Range on HMM: 1-319/513
Sequence Identity: 25% (86 aa)

YVKLEKVGEGTYGKVYKARE--------------KNSGRLVALKKTRLE---------MEEEGVPSTALREVSLLQMLS----------------QSIYV
| ...|.||||||.|||.|               ......||.|| ...         .|..|.|..||||...|..|.                .  ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VRLLCVEHVDKKGKP-------------MLYLVFEFLDTDLKKYIDLFGRGNTG-RPIPPKIIQ--------VFVDSSGFVTGFLTCVICCQSFM-----
|.|. . . ..  ..              ||||||..|.||..||.   . . | ||.| .  .                    .     ...||     
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRP-----------P---HNIKYFMIHIRY

-YQLCKGVA--HCHSHG--VMHRDLKPQNLLVDKEK-------------------GILKIADLGLGRAFTVP---------------------LKSYTHE
 ||...|..  .||||.  ..||||||.|.|.....                   |.|||.| || |.. ..                     .. |||.
MYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHY

IVTLWYRAPEVLLGATHYS---------IPVDIW
.||.||||||.|||..||.          |.|.|
VVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMW
Kinase CDKB_b.AA Pkinase 4-217 30 6.4e-62 216.82 Pfam 1-196 (293) Show / Hide 
Range on Protein: 4-217
Range on HMM: 1-196/293
Sequence Identity: 30% (68 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALR--EVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYIDLF--
|....|.|.|..|.|||...|..|..||.|. ... |..... |..|  |......| .. ..|||... .     |. .|.|.|... .|.  .|||  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED----KDHIYMVMEYCEGGLY-VMDLFDY

--GRGNTGRPIPPKIIQVFVDSSGFVTGFLTCVICCQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGIL----KIADLGLGRAF-TVPLKSYTHE
  .                 ...| .. |   ....  .|||...|...|||.|..||||||.|.|.| ..| .    ||.| || . | . .   .|. 
IST-----------------WRHGCFY-FSEWECKF--YMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTF

IVTLWYRAPEVLLGATHYSIPVDIW
 .|.||.||||..|...|. .||.|
CGTPWYMAPEVIRGGQYYGPKVDMW
Kinase CDKB_b.AA S_TKc 4-308 26 6.3e-61 209.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-308
Range on HMM: 1-231/231
Sequence Identity: 26% (88 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDT---DLKKYIDLFG
| .|.|.|.|..|||||.|.|..||.||.|. .          ...||...|..  .  ..|.|. | .        ||.|.|..|.   ||..||.  |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRG

RGNTGRPIPPKIIQVFVDSSGFVTGFLTCVICCQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRA
|. ...|.|.  .                    ...|||.|.....|||||..||||||.|.|.|.    .||.| || | .       |. ..|.||.|
RHGLRFPFPE-HA--------------------RFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMA

PEVLLGATHYSI-PVDIW---------LLGTP----NDEIWPGVSKLRDWHEFPQWKPQNISRAVPDLDPKGVDLLTVSFSISRDEPLISLFTFPSVFW-
||||    .|.  ..|.|         | | |     ....  .                                                  .. .. 
PEVL----GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG-------------------------------------------------SPEAKD

--QKMLQYDPSKRISAKAAMQ-------HPYF
  .|.||.||.||..|  |.|       ||.|
FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CDKB_b.AA CDK5 133-217 62 9.8e-52 161.49 In-house 100-183 (287) Show / Hide 
Range on Protein: 133-217
Range on HMM: 100-183/287
Sequence Identity: 62% (53 aa)

CQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGATHYSIPVDIW
..|||||| ||.| ||.| |.||||||||||. | .|.|| || || ||| .| . |.||.||||||.| ||.|. ||| ..|.|
IKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINK-NGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMW
Kinase CDKB_b.AA CDK7 135-217 50 5.8e-45 117.41 In-house 106-187 (288) Show / Hide 
Range on Protein: 135-217
Range on HMM: 106-187/288
Sequence Identity: 50% (42 aa)

SFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGATHYSIPVDIW
..| .. .|. .|| . . |||||| |||.... |.||||| || |..  | . ||| .|| |||||| | || ||   ||.|
AYMMMTLQGLEYCHRNWILHRDLKPNNLLMNEN-GQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMW
Kinase CDKB_b.AA CDK5 4-116 51 7.7e-45 139.32 In-house 1-103 (287) Show / Hide 
Range on Protein: 4-116
Range on HMM: 1-103/287
Sequence Identity: 51% (58 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYIDLFGRGN
| |.||.|||||| |||||.|... .||||. ||. | |||||||.||..||. | .   .|||  | | .||    | |||||.| |||||.| ..   
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKEL-KHKNIVRLHDVIHSEKK----LTLVFEFCDQDLKKYMDSCNG--

TGRPIPPKIIQVF
    . ..||. |
---EMDMHIIKSF
Kinase CDKB_b.AA PCTAIRE 136-217 58 5.7e-38 131.76 In-house 102-182 (291) Show / Hide 
Range on Protein: 136-217
Range on HMM: 102-182/291
Sequence Identity: 58% (48 aa)

FMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGATHYSIPVDIW
|..||  | | ||   ..||||||||||.. |.| || || || ||  || | | ||.|||||| |.||.| | || ..|.|
FLFQLLRGLAYCHRRKILHRDLKPQNLLIN-ERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMW
Kinase CDKB_b.AA PFTAIRE 136-217 57 1.6e-37 129.67 In-house 102-182 (287) Show / Hide 
Range on Protein: 136-217
Range on HMM: 102-182/287
Sequence Identity: 57% (47 aa)

FMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGATHYSIPVDIW
|..||  | . ||   |.||||||||||.  ..| || || || ||  || . | ||.|||||| | ||||.| ||  .|.|
FLFQLLRGLSYCHQRRVLHRDLKPQNLLI-SHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMW
Kinase CDKB_b.AA PITSLRE 135-217 57 4.3e-36 126.22 In-house 110-191 (295) Show / Hide 
Range on Protein: 135-217
Range on HMM: 110-191/295
Sequence Identity: 57% (48 aa)

SFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGATHYSIPVDIW
..| || .||.| |.. .||||||  |||    ||||||.| ||.| .  |.|.||  .|||||||||.|||.  || |||.|
CLMQQLLRGVEHMHDNWIMHRDLKTSNLLY-SHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMW
Kinase CDKB_b.AA CDK4 134-217 51 2e-27 91.01 In-house 113-193 (290) Show / Hide 
Range on Protein: 134-217
Range on HMM: 113-193/290
Sequence Identity: 51% (43 aa)

QSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGATHYSIPVDIW
.  | ||  ||   ||| . ||||||||.||  . | .|.|| || | .    .  |  .|||||||||||| .. |  |||.|
KHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSD-GHVKLADFGLARIYSFQMA-LTPVVVTLWYRAPEVLLQSY-YNTPVDMW
Kinase CDKB_b.AA CDK4 4-97 38 3.6e-27 90.11 In-house 1-100 (290) Show / Hide 
Range on Protein: 4-97
Range on HMM: 1-100/290
Sequence Identity: 38% (38 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEE--GVPSTALREVSLLQMLSQSIY--VVRLLCVEHVDKKGK--PMLYLVFEFLDTDLKKYID
|...  .||| ||.||.||   .|. ||||. |  ..||  |.|   .||.|..  | |.    .|.|. | ||   .    .. .|||  | ||. |.|
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREISVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDWDLHTYLD
Kinase CDKB_b.AA CRK7 133-210 43 5.2e-27 90.02 In-house 114-192 (343) Show / Hide 
Range on Protein: 133-210
Range on HMM: 114-192/343
Sequence Identity: 43% (35 aa)

CQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVPL--KSYTHEIVTLWYRAPEVLLGATHY
| .|| ||  |.. ||  ...|||.|  |.|..  .|..||||.|| | .      . ||  ..|||||.|| |||...|
CKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMN-NQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERY
Kinase CDKB_b.AA PCTAIRE 4-97 52 2.2e-26 90.18 In-house 1-88 (291) Show / Hide 
Range on Protein: 4-97
Range on HMM: 1-88/291
Sequence Identity: 52% (49 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYID
|.||.| |||||  ||| | |  . |||||  |||  ||| | || ||||||. | .   .| |  . | ..     | ||||..| |||.|.|
YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLEH-EEGAPCTAIREVSLLKDL-KHANIVTLHDIIHTHH----QLTLVFEYMDMDLKQYMD
Kinase CDKB_b.AA PFTAIRE 4-97 44 2.9e-26 89.48 In-house 1-88 (287) Show / Hide 
Range on Protein: 4-97
Range on HMM: 1-88/287
Sequence Identity: 44% (42 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYID
|.|||| |||.| .|||.. .  ...||||  ||. .|||.| || ||.|||. |  .  .| |  . | ..     | .|||...|||..|.|
YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ-QEEGTPFTAIREASLLKNLKHA-NIVCLHDIIHTKE----TLTFVFEYVHTDLCQYMD
Kinase CDKB_b.AA CRK7 4-92 40 2.9e-26 87.41 In-house 1-97 (343) Show / Hide 
Range on Protein: 4-92
Range on HMM: 1-97/343
Sequence Identity: 40% (39 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEME---EEGVPSTALREVSLLQMLS-QSIYVVRLLCVE---HVDKKGKP-MLYLVFEFLDTDL
| ... .||||||.||||. |. | .||||| |.. |   .|| | || ||. .|. |  |.|   .   ..    ...| .    |.|||  | ||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDL
Kinase CDKB_b.AA CDK 218-308 29 1.2e-25 78.87 In-house 240-284 (284) Show / Hide 
Range on Protein: 218-308
Range on HMM: 240-284/284
Sequence Identity: 29% (27 aa)

LLGTPNDEIWPGVSKLRDWHEFPQWKPQNISRAVPDLDPKGVDLLTVSFSISRDEPLISLFTFPSVFWQKMLQYDPSKRISAKAAMQHPYF
..|||....||||.|| |.                                               . .|||.|||.|||||..|.|||||
ICGTPTEDNWPGVTKLPDY----------------------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDKB_b.AA CDK7 4-96 36 3.7e-24 60.85 In-house 1-92 (288) Show / Hide 
Range on Protein: 4-96
Range on HMM: 1-92/288
Sequence Identity: 36% (35 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTR-LEMEEE---GVPSTALREVSLLQMLSQSIYVVRLLCVEHVDKKGKPMLYLVFEFLDTDLKKYI
| |....|||... ||||.....|. || || . |   .|   |.  ||.||. .|| . |   |. |. .       |  ..|||.|.|.||   |
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEM-QHDNVIGLIDIFMH----KSNIQLVFDFMDWDLEVVI
Kinase CDKB_b.AA PITSLRE 4-55 43 1.4e-19 68.06 In-house 1-55 (295) Show / Hide 
Range on Protein: 4-55
Range on HMM: 1-55/295
Sequence Identity: 43% (24 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLE--MEEEGVPSTALREVS-LL
...| ...||||| ||.|..|  .. ||||.. .|   | || | |.|||.. .|
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMIL
Kinase CDKB_b.AA CDC2 219-262 48 1.4e-16 46.93 In-house 225-278 (301) Show / Hide 
Range on Protein: 219-262
Range on HMM: 225-278/301
Sequence Identity: 48% (26 aa)

LGTPNDEIWPGVSKLRDWHE-FPQWKPQNISRAVPD---------LDPKGVDLL
|||||...||||..| |. . ||.||||..|. .|.         |||.|.|||
LGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLL
Kinase CDKB_b.AA CDC2 286-308 78 9.3e-16 44.4 In-house 279-301 (301) Show / Hide 
Range on Protein: 286-308
Range on HMM: 279-301/301
Sequence Identity: 78% (18 aa)

QKMLQYDPSKRISAKAAMQHPYF
..||||||.||||||.|.|||||
MQMLQYDPQKRISAKEALQHPYF
Kinase CDKB_b.AA CMGC 286-308 73 8.6e-15 44.14 In-house 491-513 (513) Show / Hide 
Range on Protein: 286-308
Range on HMM: 491-513/513
Sequence Identity: 73% (17 aa)

QKMLQYDPSKRISAKAAMQHPYF
.|||||||.|||.|. |.|||||
KKMLQYDPDKRITAEQALQHPYF
Kinase CDKB_b.AA CDK5 286-308 73 3.6e-13 37.47 In-house 265-287 (287) Show / Hide 
Range on Protein: 286-308
Range on HMM: 265-287/287
Sequence Identity: 73% (17 aa)

QKMLQYDPSKRISAKAAMQHPYF
|||||..| .|||||||..||||
QKMLQCNPNQRISAKAALHHPYF
Kinase CDKB_b.AA CDK5 218-262 36 3.3e-12 34.38 In-house 215-264 (287) Show / Hide 
Range on Protein: 218-262
Range on HMM: 215-264/287
Sequence Identity: 36% (18 aa)

LLGTPNDEIWPGVSKLRDWH----EFPQWKPQN-ISRAVPDLDPKGVDLL
..|||. . ||...|| |.     ..| . ..   .  || || || |||
IMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLL
Kinase CDKB_b.AA CDK4 286-308 60 1.7e-11 35.45 In-house 268-290 (290) Show / Hide 
Range on Protein: 286-308
Range on HMM: 268-290/290
Sequence Identity: 60% (14 aa)

QKMLQYDPSKRISAKAAMQHPYF
|||| |...||.|| .. |||||
QKMLCYNHHKRMSAYQCLQHPYF
Kinase CDKB_b.AA TyrKc 4-308 19 1.1e-10 -50.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-308
Range on HMM: 1-280/280
Sequence Identity: 19% (68 aa)

YVKLEKVGEGTYGKVYKAREKNSGRLVALKKTRLEMEEEGVPSTALREVSLLQML-SQSIYVVRLLCVEHVDKKGK---PMLYLVFEFLDT-DLKKYI-D
 ....| ||| .|.|||.. |   . || |. . .          .|| ... .|  .   .|||. |   ..      . |..|.|. .  |||.|. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

LFGRGNTGRPIPPKIIQVFVDSSGFVTGFLTCVICCQSFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGLGRAFTVP------LKSYT-
  ..                           |.    ||..| ..| .. ||... ||||   | ||.... . ||.| || |. .         . |. 
HRPK--------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRK

----HEI--VTLWYRAPEVLLGATH-YSIPVDIW----------------LLG-----TPNDEIWPGVSKL-RDWHEFPQWKPQNISRAVPDLDPKGVDL
    ..   . .   |||..   .. ...  |.|                  |      .|.|.   | .  |         |  .|             
KEHKGGKTMLPIRWMAPECI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P--MS-------------

LTVSFSISRDEPLISLFTFPSVFWQKMLQ---YDPSKRISAKAAMQHPYF
              .  . |.   | |.|   .||..| . ..   | .|
--------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CDKB_b.AA CDK7 286-308 30 1.6e-10 23.78 In-house 266-288 (288) Show / Hide 
Range on Protein: 286-308
Range on HMM: 266-288/288
Sequence Identity: 30% (7 aa)

QKMLQYDPSKRISAKAAMQHPYF
..|.  .|.||...  . ..|||
CGMWTMNPCKRWTCTQCLKMPYF
Kinase CDKB_b.AA PITSLRE 286-308 47 2e-10 34.4 In-house 273-295 (295) Show / Hide 
Range on Protein: 286-308
Range on HMM: 273-295/295
Sequence Identity: 47% (11 aa)

QKMLQYDPSKRISAKAAMQHPYF
..|| |.| .||.| .|..||.|
NQMLTYNPKNRITASDALKHPWF
Kinase CDKB_b.AA CRK7 287-308 50 1.1e-09 29.38 In-house 322-343 (343) Show / Hide 
Range on Protein: 287-308
Range on HMM: 322-343/343
Sequence Identity: 50% (11 aa)

KMLQYDPSKRISAKAAMQHPYF
||| .||.||..|. . ||..|
KMLCLDPKKRFTAEECLQHDWF
Kinase CDKB_b.AA PFTAIRE 286-308 65 1.2e-09 30.08 In-house 265-287 (287) Show / Hide 
Range on Protein: 286-308
Range on HMM: 265-287/287
Sequence Identity: 65% (15 aa)

QKMLQYDPSKRISAKAAMQHPYF
.||||. | .|.||..|||||||
MKMLQCEPRDRVSAQEAMQHPYF
Kinase CDKB_b.AA PCTAIRE 286-308 52 1.9e-09 29.46 In-house 269-291 (291) Show / Hide 
Range on Protein: 286-308
Range on HMM: 269-291/291
Sequence Identity: 52% (12 aa)

QKMLQYDPSKRISAKAAMQHPYF
...||| . .|.|| .||.||||
TMLLQYESKNRVSAEKAMKHPYF
Kinase CDKB_b.AA CMGC 218-262 15 3e-09 25.59 In-house 369-490 (513) Show / Hide 
Range on Protein: 218-262
Range on HMM: 369-490/513
Sequence Identity: 15% (19 aa)

LLGTPN---------------DEIWPGVSKLRDWHE---------------------------FPQWKPQNISRAVPD----------------------
.||||.               .|.||...|| ...                            ||.|.|..... .|.                      
VLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKF

-------------LDPKGVDLL
             .||...|||
KSHKFNHQFKRKCCDPQAIDLL
Kinase CDKB_b.AA Pkinase 287-308 45 2.8e-08 30.38 Pfam 272-293 (293) Show / Hide 
Range on Protein: 287-308
Range on HMM: 272-293/293
Sequence Identity: 45% (10 aa)

KMLQYDPSKRISAKAAMQHPYF
..|..||.||..|. ..|||.|
WCLCKDPKKRPTAEQILQHPWF
Kinase CDKB_b.AA PCTAIRE 218-263 35 3.6e-07 21.3 In-house 219-269 (291) Show / Hide 
Range on Protein: 218-263
Range on HMM: 219-269/291
Sequence Identity: 35% (18 aa)

LLGTPNDEIWPGVSKLRDWH--EFPQWKPQNISRAVPDLD---PKGVDLLT
.|||| .. ||||. . ..    ||....| .    | ||    .. ||||
ILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAPRLDKILKQCQDLLT
Kinase CDKB_b.AA CDK7 219-239 42 2e-06 12.63 In-house 219-239 (288) Show / Hide 
Range on Protein: 219-239
Range on HMM: 219-239/288
Sequence Identity: 42% (9 aa)

LGTPNDEIWPGVSKLRDWHEF
||||..| ||..... |  .|
LGTPTEEEWPNMCCMMDYIKF
Kinase CDKB_b.AA PFTAIRE 218-263 32 0.000153 11.89 In-house 214-265 (287) Show / Hide 
Range on Protein: 218-263
Range on HMM: 214-265/287
Sequence Identity: 32% (17 aa)

LLGTPNDEIWPGVSKLRDW--HEFP--QWKPQNISRAVPDLD--PKGVDLLT
.||||... ||||..|  .  | |.    ||..  ...| ..  |.. ||..
VLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMM
Kinase CDKB_b.AA Pkinase_Tyr 4-34 37 0.000245 15.31 Pfam 1-35 (270) Show / Hide 
Range on Protein: 4-34
Range on HMM: 1-35/270
Sequence Identity: 37% (13 aa)

YVKLEKVGEGTYGKVYKAREK----NSGRLVALKK
 ....| ||| .|.|||.. |    | .  || |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKM
Kinase CDKB_b.AA PITSLRE 218-239 40 0.000526 10.72 In-house 222-243 (295) Show / Hide 
Range on Protein: 218-239
Range on HMM: 222-243/295
Sequence Identity: 40% (9 aa)

LLGTPNDEIWPGVSKLRDWHEF
..|||.  ||||...|  |  .
EMGTPTEKIWPGWTELPHWKMM
Kinase CDKB_b.AA Pkinase_Tyr 135-178 36 0.001221 12.95 Pfam 115-157 (270) Show / Hide 
Range on Protein: 135-178
Range on HMM: 115-157/270
Sequence Identity: 36% (16 aa)

SFMYQLCKGVAHCHSHGVMHRDLKPQNLLVDKEKGILKIADLGL
.. .| .|| .. .|..  ||||   | ||.... . ||.| ||
QMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFGL
Kinase CDKB_b.AA CDK4 218-262 33 0.002041 7.34 In-house 224-267 (290) Show / Hide 
Range on Protein: 218-262
Range on HMM: 224-267/290
Sequence Identity: 33% (15 aa)

LLGTPNDEIWPGVSKLRDWHEFPQWKPQNISRAVPDLDPKGVDLL
. |.|  . ||  . |  |  ||| .|...   .|...  | |||
VMGLPPEDDWPRDVSL-PWDHFPQRHPRPFKDFCPHMCKQGDDLL