Gene PRP4_b (S.moellendorffii)

PRP4_b

Species: S.moellendorffii
Alias: PRP4_b
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: PRP4

Sequence

Name Sequence Type Origin Length Description Download
PRP4_b.AA Protein None 660 None Fasta, JSON
PRP4_b.NA RNA None 1983 None Fasta, JSON
PRP4_b.kin_dom Protein Kinase Domain None 318 None Fasta, JSON

Protein domain

Protein domains of PRP4_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PRP4_b.AA PRP4 341-658 56 1e-176 593.36 In-house 1-320 (320) Show / Hide 
Range on Protein: 341-658
Range on HMM: 1-320/320
Sequence Identity: 56% (183 aa)

YEIASSHGRGVFSTVVRARDTKAGRGEPEEVAIKIIRSNETMFKAGQMELIILNKLAGA--DLENKRHCVRLLSSFEYRNHLCLVFESLHMNLREILKKF
|.. .  | ||||.|.|.||.  |.   |.|||||||.|| | | |  || || ||  |  | . | ||||.  .|..|.|.||||| . |||||.|||.
YRVYGYCGQGVFSNVCRCRDQTRGN---EMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKY

GRNIGISLAAVRSYARQLFTALKHLRNCGVLHCDIKPDNMLVNDSKNLLKLCDFGSAMFAGENEITPYLVSRFYRAPEIILGLPYDHALDMWSVGCCLYE
|...| .| ||||||.||| ||||| .|. || ||||||.||| ||| ||.||||||    |||||||||||||||||||.| ||| . |||||||.|||
GKDVGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILVNESKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYE

LYTGKVLFPGSTNNDMLRLHMELKGPFPKKMLRKAMFTAQHFDQDLNFHAIEEDPVTKKTINRMITNVKP-KDISTLISSS--GGSDEDAKNLLNFKLLL
|||||..|||.|||.||.| |..|| .|.||.||  |  .|||| .||  .| | ||..     .|..|| ||| ..      . .... | .. || ||
LYTGKIMFPGKTNNHMLKLFMDYKGKMPNKMIRKGQFKDNHFDQNCNFMYQEVDKVTEREKVTVMTYIKPTKDIYQELIECNQRIPEDQMKKVHQFKDLL

EKIFILDPEKRLTVSQALNHPFI
.|...|||.|| |. .|| ||||
DKCLMLDPKKRITCNEALKHPFI
Kinase PRP4_b.AA DYRK 341-658 39 5.4e-140 471.38 In-house 1-320 (320) Show / Hide 
Range on Protein: 341-658
Range on HMM: 1-320/320
Sequence Identity: 39% (129 aa)

YEIASSHGRGVFSTVVRARDTKAGRGEPEEVAIKIIRSNETMFKAGQMELIILNKLAGADLENKRHCVRLLSSFEYRNHLCLVFESLHMNLREILKKFGR
||| .  |.|.|. ||...|.| .    | |||||||.|. ... .| |. || .|  .| ..| |||... .| .|||||.||| | |||.| ||. . 
YEILEYIGKGSFGQVVKCWDHKTN----EMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHF

NIGISLAAVRSYARQLFTALKHLRNC-GVLHCDIKPDNMLVND--SKNLLKLCDFGSAMFAGENEITPYLVSRFYRAPEIILGLPYDHALDMWSVGCCLY
. ..|| .||..|.|..|.||.| ..   .|||.||.| ....  .|. .|..||||. | .. .|..|..||||||||.|||.||. | ||||.||.|.
QGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQ-RIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILA

ELYTGKVLFPGSTNNDMLRLHMELKGPFPKKMLRKA--MFTAQHFDQDLNFHAIEEDPVTKK-TINRMITNVKPKDISTLI----SSSGGSDEDAKNLLN
||.||..||||....|.|.. ||..|..||.|..|.   .. ..||. . .  ..| . ..| |  .|. . .|... . .    ......  . .. ..
ELFTGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC-FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-CDDHQ

FKLLLEKIFILDPEKRLTVSQALNHPFI
|| ...| ...||.||.| ||||.||..
FKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase PRP4_b.AA CMGC 341-658 19 3.8e-99 326.49 In-house 1-513 (513) Show / Hide 
Range on Protein: 341-658
Range on HMM: 1-513/513
Sequence Identity: 19% (104 aa)

YEIASSHGRGVFSTVVRARDTKAG----------RGEPEEVAIKIIRSNETMFKAGQ-------------MELIILNKL--AGADLE----------NKR
||| .  |.| ...|...||.. .          .   |.||||.|.... .   ..              |. || .|  ..   .          .. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN

HCVRLLSSFEYRN-----------------HLCLVFESLHMNLREILKKFGR-------------------------NIGISLAAVRSYARQLFTALK--
..|.|. .| ..|                 ||.|||| . ..| ...|.  .                            ... ..| |..|....||  
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

HLRNCG--VLHCDIKPDNMLVNDSKNL-------------------LKLCDFGSAMFAGEN-----------------------EITPYLVSRFYRAPEI
..   .  ..|.|.|| | |.|. . |                   ||.||||.| . ...                        .|.| |.|.||||||
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

ILGLP----------YDHALDMWSVGCCLYELYTG--------KVLFPGSTN-----------NDMLRLHMELKGPFPKKMLRKAM--FTAQHFDQDLNF
.|| .          |. . ||||||| ..|.|||        | ||||...            |.| . ... |... .|..|..  | . ..  . ..
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHF-N-FCKHEEEW

HAIEE----------------------DPVTKKTINRMITNVKPKDISTLISSSGGSDEDAKNL----------------------------LNFKLLLE
  . .                      .  ... .|.   ...||... |.  .   |.   |                               .  ||.
PNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-N-NKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLK

KIFILDPEKRLTVSQALNHPFI
|....||.||.|..|||.||..
KMLQYDPDKRITAEQALQHPYF
Kinase PRP4_b.AA DYRK2 341-658 35 8.5e-77 249.2 In-house 1-318 (318) Show / Hide 
Range on Protein: 341-658
Range on HMM: 1-318/318
Sequence Identity: 35% (116 aa)

YEIASSHGRGVFSTVVRARDTKAGRGEPEEVAIKIIRSNETMFKAGQMELIILNKLAGADLENKRHCVRLLSSFEYRNHLCLVFESLHMNLREILKKFGR
||| .  |.| |  ||.. | | .    . ||||.||      .  ..|..|| ..   |  |   ||..| .| .|||.|..|| | ||| | .||   
YEILEVIGKGSFGQVVKCYDHKTK----QHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHF

NIGISLAAVRSYARQLFTALKHLRNCGVLHCDIKPDN-MLVNDSKNLLKLCDFGSAMFAGENEITPYLVSRFYRAPEIILGLPYDHALDMWSVGCCLYEL
. |.||. ||  |... ..|. |.   . ||| || | .|    .. .|. ||||  |. .  |  |  ||||||||.|||..|. | |||| || . ||
Q-GFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAEL

YTGKVLFPGSTNNDMLRLHMELKGPFPKKMLRKA-----MFTAQHFD----QDLNFHAIEEDPVTKKTINRMITNVKPKDISTLISSSGGSDEDAKNLLN
|||. ||||.  || . . ||. |  |||.. ..       .   |.      ..    .......| ...     .| . . . |.  |..   .|...
YTGYPLFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNSHCFEWYCTFMTDHSMEIPKHYKNRHGKRRPPGSKSWKSVLKGCED--ENFID

FKLLLEKIFILDPEKRLTVSQALNHPFI
|   . . |  ||..|.| ||||.||.|
F---IKRCFEWDPSERMTPSQALKHPWI
Kinase PRP4_b.AA S_TKc 341-658 23 2.9e-75 257.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 341-658
Range on HMM: 1-231/231
Sequence Identity: 23% (79 aa)

YEIASSHGRGVFSTVVRARDTKAGRGEPEEVAIKIIRSNETMFKAGQMELIILNKLAGADLENKRHCVRLLSSFEYRNHLCLVFESLHM---NLREILKK
|||    |.| |..| ..|..|      ..||||||.      .  . |. || |       .  . |.|. .|.  .||..|.| .     .|....||
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKK

FGR---NIGISLAAVRSYARQLFTALKHLRNCGVLHCDIKPDNMLVNDSKNLLKLCDFGSAMFAGENEITPYLVSRFYRAPEIILGLPYDH-ALDMWSVG
 ||   . ...   .|.|..|.. ||... . |..|.|.||.| |...    .|.||||.| .      | . ....|.|||..   .|.. . |.||.|
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

CCLYELYTGKVLFPGSTNNDMLRLHMELKGPFPKKMLRKAMFTAQHFDQDLNFHAIEEDPVTKKTINRMITNVKPKDISTLISSSGGSDEDAKNLLNFKL
|.|||...|. .||  . . |... .                                                                       .| 
CILYEMLCGYPPFP--QMQMMFKKIG--------------------------------------------------------------------SPEAKD

LLEKIFILDPEKRLTVSQALN-------HPFI
...|..  |||||.|. .||.       ||..
FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PRP4_b.AA DYRK1 341-658 36 5e-63 215.71 In-house 1-321 (321) Show / Hide 
Range on Protein: 341-658
Range on HMM: 1-321/321
Sequence Identity: 36% (121 aa)

YEIASSHGRGVFSTVVRARDTKAGRGEPEEVAIKIIRSNETMFKAGQMELIILNKLAGADLENKRHCVRLLSSFEYRNHLCLVFESLHMNLREILKKFGR
||| |. |.| |  ||.| |..    | |.||||||.   . .   |.|. .|  .  .| |.| . |.|   | .||||||||| |  || ..|.    
YEIDSLIGKGSFGQVVKAYDHQ----EQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNT-H

NIGISLAAVRSYARQLFTALKHLR--NCGVLHCDIKPDN-MLVNDSKNLLKLCDFGSAMFAGENEITPYLVSRFYRAPEIILGLPYDHALDMWSVGCCLY
  |.||  .| .|.|. |||  .      ..|||.||.| .|.|  .  .|. ||||.  .|.  |  |. |||||.||..||..|| |.||||.|| | 
FRGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQ-RIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILV

ELYTGKVLFPGSTNNDMLRLHMELKGPFPKKMLRKAMFTAQHFDQDLNFHAIEEDPVTKKTINRMITNVKPKDISTLISSSGGSDEDAKN--------LL
|. ||  || ||   | .   .|  |  ||.|. .|  . ..|..| .          ||  ..  .  | ..|  |   .|| .   |.         |
EMHTGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKDPDNTWYCKKTRDKKKHYKEPCTRKLHEI--LGVETGGPGGRRKGEPGHSVEDYL

NFKLLLEKIFILDPEKRLTVSQALNHPFI
 || |.... . ||..|.|  .|| |.|.
KFKDLIKRMLQYDPKQRITPYYALQHSFF
Kinase PRP4_b.AA HIPK 341-585 37 9.3e-54 167.43 In-house 1-242 (329) Show / Hide 
Range on Protein: 341-585
Range on HMM: 1-242/329
Sequence Identity: 37% (93 aa)

YEIASSHGRGVFSTVVRARDTKAGRGEPEEVAIKIIRSNETMFKAGQMELIILNKLAGADLENKRHCVRLLSSFEYRNHLCLVFESLHMNLREILKKFGR
||.    ||| |  ||..      ||  | |||||.. .    . ||.|. ||..| . . ..  | || .  |. .|| ||||| |  || . .|.  .
YEVLEFLGRGTFGQVVKCWK----RGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADE-YHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQN-K

NIGISLAAVRSYARQLFTALKHLRNCGVLHCDIKPDN-MLVNDSKN--LLKLCDFGSAMFAGENEITPYLVSRFYRAPEIILGLPYDHALDMWSVGCCLY
   . | ..|    |  |||..|.. |..| |.||.| |||  ..     |  |||||    .    .|| ||.|||||||||||.  . |||| || . 
FMPLPLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIA

ELYTGKVLFPGSTNNDMLRLHMELKGPFPKKMLRKAMFTAQHFDQDLN
||. |  |.||. . |  |   .  .   . .| .|. . . ||.| .
ELFLGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQ
Kinase PRP4_b.AA GSK 341-557 31 3.7e-47 141.72 In-house 1-230 (328) Show / Hide 
Range on Protein: 341-557
Range on HMM: 1-230/328
Sequence Identity: 31% (74 aa)

YEIASSHGRGVFSTVVRARDTKAGRGEPEE----VAIKIIRSNETMFKAGQMELIILNKLAGADLENKRHCVRLLSSFE-YRNH--------LCLVFESL
||.   .|.|.|..|..| ..  .  . |.    |||| .   .. .|  ..|| |. .|. .|  |   .|||. .|. . .         .|||.| .
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQ-DKRYK-CNRELQIMKMLGKLDHPN---IVRLKYFFYMHYEKKDENHVYCNCLVMEYM

HMNLREILKKF---GRNIGISLAAVRSYARQLFTALKHLRNCGVLHCDIKPDNMLVNDSKNLLKLCDFGSAM-FAG--ENEITPYLVSRFYRAPEIILGL
 ..| ......   ...  ...  .. |. |.| .|..|   |. | ||||.|.||....  ||.||||||         . ..| .||.||||| |.| 
PQTLYQVIRHYVKNKQQ--MPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGC

-PYDHALDMWSVGCCLYELYTGKVLFPGSTNNDMLRL
  |... |.||.||.. |. .|..|||| . .|.|..
TNYTCQIDVWSCGCVMAEMLKGQPLFPGDSSVDQLVE
Kinase PRP4_b.AA Pkinase 341-564 27 1.5e-46 165.65 Pfam 1-233 (293) Show / Hide 
Range on Protein: 341-564
Range on HMM: 1-233/293
Sequence Identity: 27% (69 aa)

YEIASSHGRGVFSTVVRARDTKAGRGEPEEVAIKIIRSNETMFKAGQM-----ELIILNKLAGADLENKRHC--VRLLSSFEYRNHLCLVFESLHM----
|.| .  |.| |..| .... . |.    .||.|||.  ..  .  |      |. |...| .       |.  |||. .||...|...|.| . .    
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N-------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYV

-NLREILK--KFGRNIGISLAAVRSYARQLFTALKHLRNCGVLHCDIKPDNMLVNDSKNL---LKLCDFGSAMF--AGENEITPYLVSRFYRAPEIIL-G
  | ....  . |. .  |   ...|..|.. .|... ..|..|.|.||.| |...  ..   .|.||||.| .     |. | . ....|.|||.|. |
MDLFDYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGG

LPYDHALDMWSVGCCLYELYTGKVLFPGS----TNNDMLRLHMELKGP
 .|... ||||.|| |||...|. .|||.    . .|.. .. . .||
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGP
Kinase PRP4_b.AA YAK 371-580 33 2e-39 131.39 In-house 27-239 (347) Show / Hide 
Range on Protein: 371-580
Range on HMM: 27-239/347
Sequence Identity: 33% (73 aa)

VAIKIIRSNETMFKAGQMELIILNKL-AGADLENKR---HCVRLLSSFEYRNHLCLVFESLHMNLREILK--KFGRNIGISLAAVRSYARQLFTALKHLR
.|.|.| .    |  .  |  ||  |    | .||    | .|.. .| ..||.||||| | .|| | ||  ||    | |   .| .  |   ..  | 
FAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF---CGFSFQLIRQWTKQILDGMCVLE

NCGVLHCDIKPDNMLVND-SKNLLKLCDFGSAMFAGENEITPYLVSRFYRAPEIILGLPYDHALDMWSVGCCLYELYTGKVLFPGSTNNDMLRLHMELKG
|  . ||| || | .     |  .|. ||||.       .. |  .|.||.||||.. .|  . |||| || . ||. |  .|||    . .    .  |
NKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSC-QEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFLGLPIFPGNSEYNQIKRIIDMLG

PFPKKMLRKAMFTAQHF
 .|  |. .  |  . |
YPPSWMIDQGRFKNKYF
Kinase PRP4_b.AA CDK 422-550 30 2.4e-32 100.65 In-house 95-229 (284) Show / Hide 
Range on Protein: 422-550
Range on HMM: 95-229/284
Sequence Identity: 30% (45 aa)

LVFESLHMNLREILKKFGRNIGISLAAVRSYARQLFTALKHLRNCGVLHCDIKPDNMLVNDSKN----LLKLCDFGSAMFAGE--------NEITPYLVS
.||| ... | ....            ...| .||  .| ..   ...| |.|| | |.|.  .     ||. ||| |   |         .. |.  | 
MVFEYMDHDLKKYMD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVT

RFYRAPEIIL-GLPYD--HALDMWSVGCCLYELYT---GKVLFPGST
. |||||. |    |.   . ||||||| ..|..|   .| ||||..
LWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDS
Kinase PRP4_b.AA CLK 341-483 32 2.8e-31 90.47 In-house 1-150 (350) Show / Hide 
Range on Protein: 341-483
Range on HMM: 1-150/350
Sequence Identity: 32% (49 aa)

YEIASSHGRGVFSTVVRARDTKAGRGEPEEVAIKIIRSNETMFKAGQMELI-ILNKLAGA-DLENKRH--CVRLLSSFEY-RNHLCLVFESLHMNLREIL
||| .  | |.|..||. .|.| |   .  ||.||||. |    | . |.  |. |.. . | .||.   |......|.|  .| |.||| .  .. . .
YEIVCTLGEGTFGKVVECWDHKNG---KKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFM

KKFG-----RNIGISLAAVRSYARQLFTALKHLRNCGVLHCDIKPDNMLVNDS
|. .     . |.  ....|. |.|| .|.| |   .  | | || | .  ||
KSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDS
Kinase PRP4_b.AA CLK 488-583 37 2.3e-26 75.43 In-house 187-288 (350) Show / Hide 
Range on Protein: 488-583
Range on HMM: 187-288/350
Sequence Identity: 37% (39 aa)

KLCDFGSAM---FAGENEITPYLVS-RFYRAPEIILGLPYDHALDMWSVGCCLYELYTGKVLFPGSTNNDMLRLHMELKG-PFPKKMLRKAM---FTAQH
.. |||||    |  ..|  . .|| | |||||.||||..    | ||.|| |.|||||  ||..  | . | .  .. | |.|. | ..      .  .
CVIDFGSATKIRF--DHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQKY

FDQD
| ..
FYHN
Kinase PRP4_b.AA CDK 634-658 48 3.1e-10 28.79 In-house 260-284 (284) Show / Hide 
Range on Protein: 634-658
Range on HMM: 260-284/284
Sequence Identity: 48% (12 aa)

LLEKIFILDPEKRLTVSQALNHPFI
||.| . .||.||.. .|||.||. 
LLNKMLCYDPKKRISAEQALQHPYF
Kinase PRP4_b.AA CLK 634-658 48 6.9e-10 25.09 In-house 326-350 (350) Show / Hide 
Range on Protein: 634-658
Range on HMM: 326-350/350
Sequence Identity: 48% (12 aa)

LLEKIFILDPEKRLTVSQALNHPFI
|..|... || ||.| ..|| ||| 
LIRKMLEYDPSKRITCKDALQHPFF
Kinase PRP4_b.AA TyrKc 341-658 15 2.3e-09 -71.11 SMART 1-280 (280) Show / Hide 
Range on Protein: 341-658
Range on HMM: 1-280/280
Sequence Identity: 15% (56 aa)

YEIASSHGRGVFSTVVRARDTKAGRGEPEEVAIKIIRSNETMFKAGQMELIILNKL-AGADLENKRHCVRLLSSFEYR-------NHLCLVFESLHM-NL
 .     |.| | .|.... .       ..||.| ....    ..   |. |. ||       .  . |||.               |..|.|     .|
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGG-----HHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

REILKKFGRNIGISLAAVRSYARQLFTALKHLRNCGVLHCDIKPDNMLVNDSKNLLKLCDFGSAMFAGEN----EITPYLV------SR-----FYRAPE
.. |.| ...  ....   |.. |      .|   .. | |.   | ||.. .   | .||| . . ..     | . | .      ..        |||
KDYLRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

IILGLPYDHALDMWSVGCCLYELYT-GKVLFPG-----STNNDMLRLHMELKGPFPKKM----LRKAMFTAQHFDQDLNFHAIEEDPVTKKTINRMITNV
 |    . .. | || | |..|..| |.   ||      .| ..... .. . . . .                                          
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------------------

KPKDISTLISSSGGSDEDAKNLLNFKLLLEKIFILDPEKRLTVSQALNHPFI
              .            . ..    |||.| | |.   | ..
--------------F---VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase PRP4_b.AA Pkinase 630-658 34 1.5e-07 27.81 Pfam 265-293 (293) Show / Hide 
Range on Protein: 630-658
Range on HMM: 265-293/293
Sequence Identity: 34% (10 aa)

NFKLLLEKIFILDPEKRLTVSQALNHPFI
..| ...... .||.||.|  |.|.||..
ECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PRP4_b.AA YAK 641-658 50 1e-06 18.22 In-house 330-347 (347) Show / Hide 
Range on Protein: 641-658
Range on HMM: 330-347/347
Sequence Identity: 50% (9 aa)

LDPEKRLTVSQALNHPFI
|.| .| . .||  ||||
LNPRERWKPMQAMQHPFI
Kinase PRP4_b.AA GSK 634-658 44 6e-06 13.41 In-house 304-328 (328) Show / Hide 
Range on Protein: 634-658
Range on HMM: 304-328/328
Sequence Identity: 44% (11 aa)

LLEKIFILDPEKRLTVSQALNHPFI
|. |... ||.|||.  .|. ||| 
LISKCLVYDPKKRLSPLEACAHPFF
Kinase PRP4_b.AA HIPK 634-658 48 1.1e-05 13.29 In-house 305-329 (329) Show / Hide 
Range on Protein: 634-658
Range on HMM: 305-329/329
Sequence Identity: 48% (12 aa)

LLEKIFILDPEKRLTVSQALNHPFI
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VLKKMCTWDAHKRITPCEALNHPFV
Kinase PRP4_b.AA CDK 341-377 36 8.7e-05 11.06 In-house 1-38 (284) Show / Hide 
Range on Protein: 341-377
Range on HMM: 1-38/284
Sequence Identity: 36% (14 aa)

YEIASSHGRGVFSTVVRARDTKAG-RGEPEEVAIKIIR
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YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIR