Gene YAK_d (S.moellendorffii)

YAK_d

Species: S.moellendorffii
Alias: YAK_d
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: YAK

Sequence

Name Sequence Type Origin Length Description Download
YAK_d.AA Protein None 74 None Fasta, JSON
YAK_d.NA RNA None 225 None Fasta, JSON
YAK_d.kin_dom Protein Kinase Domain None 55 None Fasta, JSON

Protein domain

Protein domains of YAK_d.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase YAK_d.AA AGC 23-62 45 2.9e-19 45.03 In-house 161-202 (395) Show / Hide 
Range on Protein: 23-62
Range on HMM: 161-202/395
Sequence Identity: 45% (19 aa)

QLLEALQVLER-HGVVHRD-LKPENIVLSSQGELRLIDFGSA
... ||. | . .|..||| ||||||.| ..| ..| |||..
CIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLC
Kinase YAK_d.AA CMGC 16-62 25 4.2e-18 55.23 In-house 175-251 (513) Show / Hide 
Range on Protein: 16-62
Range on HMM: 175-251/513
Sequence Identity: 25% (20 aa)

DKMSIM------TQLLEALQ--VLERHG--VVHRDLKPENIVLSSQGEL--------------------RLIDFGSA
.. ..|       |.|..|    . .|.  ..||||||||| .....||                    ...|||.|
NIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase YAK_d.AA PDK1 23-62 45 1.8e-15 43.36 In-house 118-157 (307) Show / Hide 
Range on Protein: 23-62
Range on HMM: 118-157/307
Sequence Identity: 45% (18 aa)

QLLEALQVLERHGVVHRDLKPENIVLSSQGELRLIDFGSA
... ||. | ..|..||||||||| |.. . . ..|||.|
EIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTA
Kinase YAK_d.AA CAMK 20-62 31 4.1e-15 44.46 In-house 184-243 (425) Show / Hide 
Range on Protein: 20-62
Range on HMM: 184-243/425
Sequence Identity: 31% (19 aa)

IMTQLLEALQVLERHGVVHRDLKPENIVLSSQ-----------------GELRLIDFGSA
.. |...|.. .  |..|||||||||| |..                  . . .|||| |
YFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFA
Kinase YAK_d.AA CDK 19-62 40 5.4e-15 44.25 In-house 112-160 (284) Show / Hide 
Range on Protein: 19-62
Range on HMM: 112-160/284
Sequence Identity: 40% (20 aa)

SIMTQLLEALQVLERHGVVHRDLKPENIVLSSQGE-----LRLIDFGSA
..| |||..|  . .....|||||| || ....||     | . ||| |
CYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLA
Kinase YAK_d.AA MSK 20-62 45 1.1e-14 46.11 In-house 106-151 (277) Show / Hide 
Range on Protein: 20-62
Range on HMM: 106-151/277
Sequence Identity: 45% (21 aa)

IMTQLLEALQVLERHGVVHRDLKPENIVLSSQ---GELRLIDFGSA
|| .|  |.. .   |..||||||||| . ..   |...|||||.|
IMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFA
Kinase YAK_d.AA CDC2 19-60 38 1.5e-14 40.65 In-house 107-148 (301) Show / Hide 
Range on Protein: 19-60
Range on HMM: 107-148/301
Sequence Identity: 38% (16 aa)

SIMTQLLEALQVLERHGVVHRDLKPENIVLSSQGELRLIDFG
|.| |.|...  . .....|||||| || ....|.... |||
SYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFG
Kinase YAK_d.AA RSK 20-62 39 2.1e-14 49.34 In-house 109-154 (278) Show / Hide 
Range on Protein: 20-62
Range on HMM: 109-154/278
Sequence Identity: 39% (18 aa)

IMTQLLEALQVLERHGVVHRDLKPENIVLSS---QGELRLIDFGSA
.| ..  |.. |  .|..|||||||||.. .   .|...|.||| .
YMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFC
Kinase YAK_d.AA CDK4 20-60 48 4.7e-14 44.41 In-house 115-155 (290) Show / Hide 
Range on Protein: 20-60
Range on HMM: 115-155/290
Sequence Identity: 48% (20 aa)

IMTQLLEALQVLERHGVVHRDLKPENIVLSSQGELRLIDFG
.| ||| ..  |  | ..||||||.|| ..|.|.. | |||
MMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGHVKLADFG
Kinase YAK_d.AA CAMKL 22-62 44 6.3e-14 40.68 In-house 134-176 (297) Show / Hide 
Range on Protein: 22-62
Range on HMM: 134-176/297
Sequence Identity: 44% (19 aa)

TQLLEALQVLERHGVVHRDLKPENIVLSSQG--ELRLIDFGSA
.|...|.. . .||.||||.||||| |...|   . .|||| .
RQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFS
Kinase YAK_d.AA Pkinase 19-62 39 2.8e-13 48.05 Pfam 112-159 (293) Show / Hide 
Range on Protein: 19-62
Range on HMM: 112-159/293
Sequence Identity: 39% (19 aa)

SIMTQLLEALQVLERHGVVHRDLKPENIVLSSQGEL----RLIDFGSA
..|.|.|..|. . ..|..||||||||| ....|..    ...|||.|
FYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA