Gene MAK_a (S.moellendorffii)

MAK_a

Species: S.moellendorffii
Alias: MAK_a
External Links:
Annotation:

Classification

Group: CMGC
Family: RCK
Subfamily: MAK

Sequence

Name Sequence Type Origin Length Description Download
MAK_a.AA Protein None 381 None Fasta, JSON
MAK_a.NA RNA None 1146 None Fasta, JSON
MAK_a.kin_dom Protein Kinase Domain None 126 None Fasta, JSON

Protein domain

Protein domains of MAK_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MAK_a.AA RCK 24-148 58 1.2e-79 252.36 In-house 1-133 (298) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-133/298
Sequence Identity: 58% (78 aa)

YQVIKQVGDGTYGSVWKAIDRCTNEFVAIKKMKTKFHGWEECMNLREVKCLQRLD-HPNIVQLKEVIWEHG--ELFLVFEYMECNLYQVMKD---RSKML
||.|||.||||||.| ||..  |.|.|||||||.||. |||||||||.| | .|  ||||..||||| .    .|..|||||. |||| |||   | | |
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYL

SEER--IRIWSFQVLRALDYMHQHGIFHRDLKP
.|.   |.   .|.| .|..|| ||.|||||||
PENQRSIKNIMYQILQGLAHMHKHGFFHRDLKP
Kinase MAK_a.AA MAK 24-148 48 2.7e-73 232.54 In-house 1-159 (352) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-159/352
Sequence Identity: 48% (77 aa)

YQVIKQVGDGTYGSVWKAID------------------------------RCTNEFVAIKKMKTKFHGWEECMNLREVKCLQRLD-HPNIVQLKEVIW--
||.|||.||||||.| .|..                                | | ||||.||.||. ||||||||||| |  |  |||||.|||||   
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDS

EHGELFLVFEYMECNLYQVMKDRSK-MLSEERIRIWSFQVLRALDYMHQHGIFHRDLKP
|  .|..|||||. |||| |||| . ...|  ||   .|.| .| .||.|| ||||.||
ENDHLYFVFEYMKENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKP
Kinase MAK_a.AA RCK 149-251 52 1.3e-59 187.67 In-house 196-298 (298) Show / Hide 
Range on Protein: 149-251
Range on HMM: 196-298/298
Sequence Identity: 52% (54 aa)

DIWAMGAIMAELFNLQPLFPGASEADEIYKICSVLGSPNYHTWPDGMQLAVRKGFRFPQFAPAGLQSLIPSASPAAVDMISAMLCWDPNRRPTAYQLRQH
||||.|.||.||  |.|||||.|| |.|.|||.|.|.||  .|||| .||  ..|.|||  . .|..|||..|. ... .  ||.|||. |.||.|. ||
DIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQH

PFF
|.|
PYF
Kinase MAK_a.AA CMGC 24-148 28 1.1e-57 187.75 In-house 1-212 (513) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-212/513
Sequence Identity: 28% (61 aa)

YQVIKQVGDGTYGSVWKAIDRCTN--------------EFVAIKKMKTKFHGWEEC----------MNLREVKCLQRL-----------------DHPNI
|..||..| |||| |.|..|. ||              |.|||||.| .|. ....          . |||.|.|..|                 .|.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VQLKEVIWEHG-----------------ELFLVFEYMECNLYQVMKDRSK--------MLSEER------------IRIWS------FQVLRALD--YMH
|.|....  ..                 .|.||||||...|||..|. ..         |||              |.  .      .|.||.|.  |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

QHG--IFHRDLKP
.|.  |.||||||
SHWGNIIHRDLKP
Kinase MAK_a.AA S_TKc 24-251 24 9e-56 192.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 24-251
Range on HMM: 1-231/231
Sequence Identity: 24% (70 aa)

YQVIKQVGDGTYGSVWKAIDRCTNEFVAIKKMKTKFHGWEECMNLREVKCLQRLDHPNIVQLKEVIWEHGELFLVFEYMEC---NLYQVMKDRSKM----
|......| |..|.|.|.... |.. ||||..|        .. .||...|.. .|||||.|..|. . ..|..|.||..    .|....|.| .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSEERIRIWSFQVLRALDYMHQHGIFHRDLKP------------------------------------------DIWAMGAIMAELFNLQPLFPGASEA
 ..| ..| .  |...||.|.|.||| ||||||                                          |.|. | |..|..  .|.||   . 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP---QM

DEIYKICSVLGSPNYHTWPDGMQLAVRKGFRFPQFAPAGLQSLIPSASPAAVDMISAMLCWDPNRRPTAYQLRQ-------HPFF
....|..                                        || | |.|. .|..||..|||| .. |       ||.|
QMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MAK_a.AA MAK 149-251 46 5.8e-54 169.95 In-house 230-352 (352) Show / Hide 
Range on Protein: 149-251
Range on HMM: 230-352/352
Sequence Identity: 46% (57 aa)

DIWAMGAIMAELFNLQPLFPGASEADEIYKICSVLGSPNYHT----------------WPDGMQLAVRKGFRFPQFAP---AGLQSLIPSASP-AAVDMI
|.||.|.|||||. . |||||.|| |.|.|||.|||.|.  .                |||| |||   .|||||  |     |..|||..|.  |....
DMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTPKKDDDFVNTNHITAPPPGGFWPDGYQLAHMMNFRFPQCVPPSIMPLKHLIPNCSQSDAIELM

SAMLCWDPNRRPTAYQLRQHPFF
  || ||||.|||| |. ..|.|
KDMLQWDPNKRPTAQQCCKYPYF
Kinase MAK_a.AA CDK 24-148 34 2e-48 152.98 In-house 1-136 (284) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-136/284
Sequence Identity: 34% (50 aa)

YQVIKQVGDGTYGSVWKAIDRCTN-----EFVAIKKMKTKFHG---WEECMN---LREVKCLQRLDHPNIVQLKEVIWEH-----------GELFLVFEY
|. ....| |||| | ||.|. |.     ..||.|| ..   |    .| ..   .||...|. | |||||.|..|.  .             |..||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

MECNLYQVMKDRSKMLSEERIRIWSFQVLRALDYMHQHGIFHRDLKP
|.  |...|.          |. . .| ||.|.|.|...| ||||||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKP
Kinase MAK_a.AA CDC2 24-148 37 5.6e-45 135.86 In-house 1-131 (301) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-131/301
Sequence Identity: 37% (50 aa)

YQVIKQVGDGTYGSVWKAIDRCTNEFVAIKKMKTKFHGWEE----CMNLREVKCLQRLD-HPNIVQLKEVIWEHGELFLVFEYMECNLYQVMK-DRS--K
|| |. .| |||| | |..|. ||. ||.|| ... .  |.       .||  ||. |. |||||.|..|| .   |..||||....| . |.   .  |
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLE-QEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNK

MLSEERIRIWSFQVLRALDYMHQHGIFHRDLKP
 .... ..   .| |..... ||..|.||||||
HMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKP
Kinase MAK_a.AA CDK7 24-148 36 4.4e-44 115.0 In-house 1-130 (288) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-130/288
Sequence Identity: 36% (48 aa)

YQVIKQVGDGTYGSVWKAIDRCTNEFVAIKKMKTKFHGWE-----ECMNLREVKCLQRLDHPNIVQLKEVIWEHGELFLVFEYMECNLYQVMKDRSKMLS
|. ||..| |... | || |  |.. ||||| | . |  |     .   .||.| || . |.|.. |  ..     . |||..|.  |  | || |  | 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

EERIRIWSFQVLRALDYMHQHGIFHRDLKP
   |  .  ..|. | |.|.. | ||||||
PAHIKAYMMMTLQGLEYCHRNWILHRDLKP
Kinase MAK_a.AA Pkinase 24-148 31 2e-41 147.59 Pfam 1-136 (293) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-136/293
Sequence Identity: 31% (43 aa)

YQVIKQVGDGTYGSVWKAIDRCTNEFVAIKKMKTKFHGWEECMNLR---EVKCLQRLDHPNIVQLKEVIWEHGELFLVFEYMEC-----NLYQVMK-DRS
|......| |..|.|.|.... |.. ||.|..| .   .......|   |.. ..||.|||||.|...  ..... .|.||.|.      |. ... .|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KML--SEERIRIWSFQVLRALDYMHQHGIFHRDLKP
. .  ||. .. .  |.||.|.|.|..|| ||||||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKP
Kinase MAK_a.AA MAPK 24-148 32 8.7e-39 131.65 In-house 1-145 (328) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-145/328
Sequence Identity: 32% (48 aa)

YQVIKQVGDGTYGSVWKAIDRC------TNEFVAIKKMKTKFHGWEECMN-LREVKCLQRL-DHPNIVQLKEVIWEH-----------GELFLVFEYMEC
|| .|..| | || |..|||..      ....|||||.   |.    |   .||.|.|... .|.||. |....  .            .. .|.|.||.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

NLYQVMK-DRSKMLSEERIRIWSFQVLRA--LDYMHQHGIFHRDLKP
.|.|..| ..  .||...|.   .|.||.  | |.|  .. ||||||
DLHQIIKSQQ--PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKP
Kinase MAK_a.AA MOK 24-148 38 4.2e-37 113.48 In-house 1-128 (283) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-128/283
Sequence Identity: 38% (49 aa)

YQVIKQVGDGTYGSVWKAIDRCTNEFVAIKKMKTKFHGWEECMNLREVKCLQRLD-HPNIVQLKEVIWEH--GELFLVFEYMECNLYQVMKDRSKMLSEE
|. | ..|.||.  | |       .. | |.|| .|   |.  ||||.. ..||. ||||..|.||...   |.| |. | |. |.| ... |   |...
YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQK

RIRIWSFQVLRALDYMHQHGIFHRDLKP
.|. . .|....|| ||  |||||| ||
KIMHYMYQLCKSLDHMHRNGIFHRDVKP
Kinase MAK_a.AA CMGC 149-251 21 2e-35 113.22 In-house 317-513 (513) Show / Hide 
Range on Protein: 149-251
Range on HMM: 317-513/513
Sequence Identity: 21% (43 aa)

DIWAMGAIMAELFN--------LQPLFPGASE-----------ADEIYKICSVLGSPN---------------YHTWPDGMQ------------------
|.|. | |.||...        ..||||| ||            | ..||. |||.|.                 .||.  .                  
DMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTN

-------LAVRKGFRFPQFAPAGLQSLIPS-----------------------------------ASPAAVDMISAMLCWDPNRRPTAYQLRQHPFF
       .......|||.. |  ...|.|                                    ..| |.| .. ||..||..|.|| |  |||.|
HWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase MAK_a.AA CDKL 24-148 35 9.4e-32 105.84 In-house 1-126 (286) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-126/286
Sequence Identity: 35% (45 aa)

YQVIKQVGDGTYGSVWKAIDRCTNEFVAIKKMKT-KFHGWEECMNLREVKCLQRLDHPNIVQLKEVIWEHGELFLVFEYMECNLYQVMKDRSKMLSEERI
|  .  || | || | |  .. |.. ||||| |  .    .    .||.| |  | |.|||.|.||    ..|.|||||.. ..  . . . . . |...
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEEYPNGVDEHVV

RIWSFQVLRALDYMHQHGIFHRDLKP
|   .|.|.|... |.| . ||| ||
RKYMWQILKAINFCHKHNCIHRDIKP
Kinase MAK_a.AA CDK5 24-148 34 1.3e-31 96.75 In-house 1-126 (287) Show / Hide 
Range on Protein: 24-148
Range on HMM: 1-126/287
Sequence Identity: 34% (44 aa)

YQVIKQVGDGTYGSVWKAIDRCTNEFVAIKKMKTKFH-GWEECMNLREVKCLQRLDHPNIVQLKEVIWEHGELFLVFEYMECNLYQVMKDRSKMLSEERI
|. .  .|.|||| |.|| .. | |.||.|. .         .  .||.  |. | |.||| |  ||     | ||||..   |   | ..   .. . |
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

RIWSFQVLRALDYMHQHGIFHRDLKP
.   .| |. | . |.| . ||||||
KSFMYQLLKGLAFCHEHHVLHRDLKP
Kinase MAK_a.AA CDC2 149-251 36 1.3e-29 87.73 In-house 188-301 (301) Show / Hide 
Range on Protein: 149-251
Range on HMM: 188-301/301
Sequence Identity: 36% (42 aa)

DIWAMGAIMAEL---FNLQPLFPGASEADEIYKICSVLGSPNYHTWPDGMQLAVRKGFRFPQFAPAGLQSLIPS---------ASPAAVDMISAMLCWDP
|.|. | |.||.    .  |||.| || |...||  .||.||  |||.  ||   |   ||.. | .|....|.         . | ..| .. ||. ||
DMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKN-TFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDP

NRRPTAYQLRQHPFF
..| .| .  |||.|
QKRISAKEALQHPYF
Kinase MAK_a.AA CDK 149-251 33 3e-29 90.6 In-house 204-284 (284) Show / Hide 
Range on Protein: 149-251
Range on HMM: 204-284/284
Sequence Identity: 33% (35 aa)

DIWAMGAIMAELFN---LQPLFPGASEADEIYKICSVLGSPNYHTWPDGMQLAVRKGFRFPQFAPAGLQSLIPSASPAAVDMISAMLCWDPNRRPTAYQL
|.|. | |.||.|.    .||||| || | . ||. ..|.|.  .||.  .|                            | .. ||| ||..| .| | 
DMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKMLCYDPKKRISAEQA

RQHPFF
 |||.|
LQHPYF
Kinase MAK_a.AA CDK7 149-251 30 3.3e-27 69.14 In-house 185-288 (288) Show / Hide 
Range on Protein: 149-251
Range on HMM: 185-288/288
Sequence Identity: 30% (32 aa)

DIWAMGAIMAELFNLQPLFPGASEADEIYKICSVLGSPNYHTWPDGMQLAVRKGFR-FPQFAPAGLQSLIPSASPAAVDMISAMLCWDPNRRPTAYQLRQ
|.|..| |.|||    | .|| |. | . .|.. || |.  .||.  ...    |. || ..   |. .   ||  ..|... |.  .| .| |. |  .
DMWSVGCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLK

HPFF
.|.|
MPYF
Kinase MAK_a.AA CDK5 149-251 29 9.1e-27 81.2 In-house 181-287 (287) Show / Hide 
Range on Protein: 149-251
Range on HMM: 181-287/287
Sequence Identity: 29% (32 aa)

DIWAMGAIMAELF-NLQPLFPGASEADEIYKICSVLGSPNYHTWPDGMQLAVRK--GFRFPQFAPAG-LQSLIPSASPAAVDMISAMLCWDPNRRPTAYQ
|.| .| |.||.  ...|||||... |.  .|  ..|.|.  .||   .|   |     .| . .   .|...|. .    |. . ||  .|| | .| .
DMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKA

LRQHPFF
  .||.|
ALHHPYF
Kinase MAK_a.AA MOK 149-251 33 2.8e-24 72.58 In-house 181-283 (283) Show / Hide 
Range on Protein: 149-251
Range on HMM: 181-283/283
Sequence Identity: 33% (34 aa)

DIWAMGAIMAELFNLQPLFPGASEADEIYKICSVLGSPNYHTWPDGMQLAVRKGFRFPQFAPAGLQSLIPSASPAAVDMISAMLCWDPNRRPTAYQLRQH
|.|. | .  |.  |.|||||. | | | ||  |.| |  ..     . .    . ||    .|.. |.| ... ..... .|  .||  | || |  ||
DMWSVGCVFYEIASLHPLFPGVNEVDQISKIHDVMGTPCQKILNKFKNQSRAMNYDFPFKKGSGIEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQH

PFF
|.|
PYF
Kinase MAK_a.AA Pkinase 149-251 31 6.7e-22 78.52 Pfam 194-293 (293) Show / Hide 
Range on Protein: 149-251
Range on HMM: 194-293/293
Sequence Identity: 31% (34 aa)

DIWAMGAIMAELFNLQPLFPGA----SEADEIYKICSVLGSPNYHTWPDGMQLAVRKGFRFPQFAPAGLQSLIPSASPAAVDMISAMLCWDPNRRPTAYQ
|.|..| |..|... .|.|||.    . .|....|| ..| |.   ||       .. ||. . .   .. . . .|... | |. .||.||..|||| |
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQ

LRQHPFF
. |||.|
ILQHPWF
Kinase MAK_a.AA MAPK 149-251 30 5.6e-20 65.58 In-house 216-328 (328) Show / Hide 
Range on Protein: 149-251
Range on HMM: 216-328/328
Sequence Identity: 30% (34 aa)

DIWAMGAIMAELFN-LQPLFPGASEADEIYKICSVLGSPNYHTWPDGM-QLAVRKGFR----FPQFAPAGLQSLIPS----ASPAAVDMISAMLCWDPNR
|.|. | |.||. .  .||||| .  | . .| .|||.|  . .       ..|. ..    .|.  .  .....|     |.| |.|... || .||..
DMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDK

RPTAYQLRQHPFF
| |. .  |||.|
RITVEEALQHPYF
Kinase MAK_a.AA CDKL 149-251 34 9.7e-18 57.22 In-house 182-286 (286) Show / Hide 
Range on Protein: 149-251
Range on HMM: 182-286/286
Sequence Identity: 34% (38 aa)

DIWAMGAIMAELFNLQPLFPGASEADEIYKICSVLGSPNYHTWPDGMQLAVRK----GFRFPQF-APAGLQSLIPSAS-PAAVDMISAMLCWDPNRRPTA
|||| | .|||..  |||.|| |. |  |.|  .||       |. ...   .    | .||.   .  | .  | .| ..| |.. ..|  || .|.|.
DIWAIGCVMAEMIDGQPLWPGQSDIDQLYHIQKCLG----PLIPRHQEIFSKNPFFHGMKFPEIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTC

YQLRQHPFF
 || .||.|
EQLMHHPYF
Kinase MAK_a.AA Pkinase_Tyr 24-146 24 4.3e-12 41.59 Pfam 1-137 (270) Show / Hide 
Range on Protein: 24-146
Range on HMM: 1-137/270
Sequence Identity: 24% (34 aa)

YQVIKQVGDGTYGSVWKAIDR----CTNEFVAIKKMKTKFHGWE--ECMNLREVKCLQRL-DHPNIVQLKEVIW-EHGE--LFLVFEYMEC-NLYQVMKD
 . .|. | | .|.|.|.. .     |.  ||.|..| . .  .    . .||.| .  | .|||||.|  |.  . .   ...|.|||.. .|.   ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R---SKMLSEERIRIWSFQVLRALDYMHQHGIFHRDL
.    . |. ...  ...|. ....| ..... ||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase MAK_a.AA TyrKc 24-251 17 3e-09 -73.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 24-251
Range on HMM: 1-280/280
Sequence Identity: 17% (51 aa)

YQVIKQVGDGTYGSVWKAIDRCTNEFVAIKKMK-TKFHGWEECMNLREVKCLQRL--DHPNIVQLKEVIWEH-------GELFLVFEYMEC-NLYQVMKD
 . .|. | | .| |.|.. .   . ||.|..|  .     . . .|| . . .|  .|||||.|  |. ..       . |..|.|||.  .| .  ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RSKMLSEERIRIWSFQVLRALDYMHQHGIFHRDL--------KPD-----------IWAMG-------AIMAELF--NLQPLFP---GASEADEIYKICS
. . |. .    ...|. .  .| |.... ||||        ..             .  .                .   ..|    | |.   |....
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

VL-----------------GSPNYH-----TWPDGMQLAVRKGFRFPQFAP----AGLQSLIPSASPAAVDMISAMLCWDPNRRPTAYQLRQHPFF
                   ..| .        .. .   |..|.| || .     .   .  . ....  ....     ||. |||  ..  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---F--VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF