Gene PEK-S1_r (S.moellendorffii)

PEK-S1_r

Species: S.moellendorffii
Alias: PEK-S1_r
External Links:
Annotation:

Classification

Group: Other
Family: PEK
Subfamily: PEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
PEK-S1_r.AA Protein None 370 None Fasta, JSON
PEK-S1_r.NA RNA None 1110 None Fasta, JSON
PEK-S1_r.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of PEK-S1_r.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PEK-S1_r.AA WEE 106-265 23 2.9e-25 81.74 In-house 1-181 (297) Show / Hide 
Range on Protein: 106-265
Range on HMM: 1-181/297
Sequence Identity: 23% (47 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVI-KVRTATKSRDQDVALVFKEGEMFQ---RCE-HPNIVKYFDMWKEEGEPGKSKVYIVMEFCGRS----
....  .|.| .|.|||||...| .|||||.. . .  ...|.. .  | .  . .     |. ||.||.|.  |.|     ... ||.||.| ..    
FQEVQKIGEGSFGEVYKCRCRIDGCIYAIKKSKQPFRGYSERKRALREV-YAHMVLGQIMDCDHHPHIVRYYSAWEE-----DDHMYIQMEYCNGGSNLL

--LQSVLLG-----GESPPADAFRQLLQAVAHV*VGFMVWPISHDN-VGVHGDIAPHNIFVTDDG--------------------RIKLGDFGLAKN
  ...  .       |.   . .....|...|.          |.|   || || | |||.. ..                    ..|.||||....
QFWIQQCHNWNHWLPEWMIWQILVDICQGLHHI----------HSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVTD
Pkinase PEK-S1_r.AA Pkinase 106-221 27 3.6e-25 90.06 Pfam 1-123 (293) Show / Hide 
Range on Protein: 106-221
Range on HMM: 1-123/293
Sequence Identity: 27% (35 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVIKVRTATKSRDQDVALVFKEGEMFQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFCGR-----SLQ--
|... ..|.|..|.||||. | ...|.|.|.||.|.. .. ||  ..   | .. .|. |||||...|.. .     |...|.|||.|.      .|   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDY

-----SVLL-GGESPPADAFRQLLQAVAH
     .  . . |    . ..|.|.....
ISTWRHGCFYFSEWECKFYMYQILRGLEY
Kinase PEK-S1_r.AA STE 106-201 22 1.1e-23 80.55 In-house 1-128 (359) Show / Hide 
Range on Protein: 106-201
Range on HMM: 1-128/359
Sequence Identity: 22% (29 aa)

YEVLACVGQGASGKVYKCRSKE---------------DEQIYAIKVIKVRTATKSRDQ-------------DVALVFKEGEMFQRCE--HPNIVKYFDMW
.| . ..|.||.|.|||.. ..                 .|.|||...... ...  .             ..  . || .. ..|   |||||||... 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

KEEGEP--GKSKVYIVMEFCG-RSLQSVL
  ||..   .....|.||...  || ...
FKEGHNHKNDDELWICMEYMDGGSLDDII
Kinase PEK-S1_r.AA STE20 106-194 33 1.7e-23 82.94 In-house 1-91 (288) Show / Hide 
Range on Protein: 106-194
Range on HMM: 1-91/288
Sequence Identity: 33% (31 aa)

YEVLACVGQGASGKVYKCRSKEDEQI----YAIKVIKVRTATKSRDQDVALVFKEGEMFQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFCG
|| | ..|||..|||||.. |.  ..    .|||.......   . ... ...||  . ..| |||||||..    . ..  .. .||||.||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ-DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTC-DDELWIVMEYCG
Kinase PEK-S1_r.AA KHS 106-263 34 2.8e-22 71.6 In-house 1-143 (258) Show / Hide 
Range on Protein: 106-263
Range on HMM: 1-143/258
Sequence Identity: 34% (57 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVIKVRTATKSRDQDVALVFKEGEMFQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFCGR-SLQSV--LL
||.|  || |  | ||| | .. ... |.||||.       ..|.|.. .|  |.. |.||||| ||  .       . |..|.||.||  ||| .  . 
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEP-----GDDFAVIQQEIMMMKDCRHPNIVAYFGSYLR-----RDKLWICMEYCGGGSLQDIYHVT

GGESPPADAF--RQLLQAVAHV*VGFMVWPISHDNVGVHGDIAPHNIFVTDDGRIKLGDFGLA
|  |    |.  |. ||.....          | .  .| ||   || .||.| .|| |||..
GPLSELQIAYVCRETLQGLHYL----------HSMGKMHRDIKGANILLTDQGDVKLADFGVS
Kinase PEK-S1_r.AA S_TKc 106-366 23 5e-21 77.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 106-366
Range on HMM: 1-231/231
Sequence Identity: 23% (66 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVIKVRTATKSRDQDVALVFKEGEMFQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFCGR---SLQSVLL
||.|  .|.|| ||||||| |.. .|.|||.||              . .| .. ..  ||||||..|.. .      ...|.|||.|.    .| ... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIK

GGESPP---------ADAFRQLLQAVAHV*VGFMVWPISHDNVGVHGDIAPHNIFVTDDGRIKLGDFGLAKNKESMLTTENIKKGRAVYSSPQRRSNST-
   ...         .  ..|...|...           |..  .| |. | ||....  .||..|||||.         .   |   | .|   . .. 
KRGRHGLRFPFPEHARFYMYQICCALEYC----------HSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVLGYGKC

YTDMLALGVILFELHWRCPPDQERESVLIDVRDGFLPADWAYQHPSIAPK--VLELVAARRDQRPSAHDILC-------DPAW
  |. ..|.||.|.  ..|| .  . .....              |   |  .  .     ..||.| ..|        .|  
KCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PEK-S1_r.AA CAMK 111-193 18 1.3e-20 62.53 In-house 1-142 (425) Show / Hide 
Range on Protein: 111-193
Range on HMM: 1-142/425
Sequence Identity: 18% (27 aa)

CVGQGASGKVYKCRSKEDE------------QIYAIKVIKVRTATKS-----------------------RDQDVALVFKEGEMFQRCE-------HPNI
  |.|. |||..|. |..             | .|||.|. . ....                       |..| . |..| |. ...        ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKYFDMWKEEG------EPG---------KSKVYIVM---EFC
.| ....  .       . .         ....|.||   |.|
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYC
Kinase PEK-S1_r.AA PEK 238-366 23 5.1e-20 65.77 In-house 449-655 (655) Show / Hide 
Range on Protein: 238-366
Range on HMM: 449-655/655
Sequence Identity: 23% (48 aa)

VHGDIAPHNIFVTDDGR-----IKLGDFGLAKNKE--------------SMLTTENIKK-----------------------------------------
.| |. |.|||...||.     .| ||||||.| |              | .  .....                                         
IHRDLKPSNIFLDCDGQHHQMQVKIGDFGLATNHEMLSQSQKNYNQQDQSYWKYVANDNCQWWNTNQQNSPTGQDTHMWSNNYHIQPTSMFYCEHCHHTG

--GRAVYSSPQRRSNS-----TYT---DMLALGVILFELHWRCPPDQ-ERESVLIDVRD------GFLP-ADWAYQHPSIAPKVLELVAARRDQRPSAHD
  |.. |.||.  |..      |.   || .||.|.||.. .    . ||  .| |.||      | .|  ...  .|  |  .. ..    .||||| .
GVGTCLYMSPEQLSGQHYQKSHYNHKVDMYSLGIIFFEMWYPFFTTMMERVKTLTDLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQ

ILCDPAW
||  .  
ILQHEFF
Kinase PEK-S1_r.AA NEK 106-193 34 3.8e-19 64.39 In-house 1-88 (286) Show / Hide 
Range on Protein: 106-193
Range on HMM: 1-88/286
Sequence Identity: 34% (33 aa)

YEVLACVGQGASGKVYKCRSKEDEQI-----YAIKVIKVRTATKSRDQD--VALVFKEGEMFQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFC
||..  .|||. |||||.|.|.|...     |..| |..   .    |.       .|    ..  |||||||.| . ||.   ... .||||.|
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQN----NEVRILKQLKHPNIVKYYDSFIEEQ---NNCLCIVMEYC
Kinase PEK-S1_r.AA CMGC 106-221 16 2.5e-18 55.99 In-house 1-197 (513) Show / Hide 
Range on Protein: 106-221
Range on HMM: 1-197/513
Sequence Identity: 16% (33 aa)

YEVLACVGQGASGKVYKCRS--------------KEDEQIYAIKVIKVRTATKSR-----DQDVAL--VFKEGEMFQRCE-----------------HPN
||..  .|.|. |.|||||               .|...|.||| || .   .         |.     . | .. ..                   |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVKYFDMWKEEGEPGKS------------KVYIVMEFCGRSLQSVLLGGES--------PPADAF-----------------------RQLLQAVA--H
||| .|. . ... |.             ..|.|.|... .|  ..             |  .                         .|.|....  .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY
Kinase PEK-S1_r.AA NEK1 106-193 35 8.9e-18 58.38 In-house 1-82 (276) Show / Hide 
Range on Protein: 106-193
Range on HMM: 1-82/276
Sequence Identity: 35% (31 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVIKVRTATKSRDQDVALVFKEGEMFQRCEHPNIVKYFDMWKEEGEPGKSKVYIVMEFC
|...  .|.|. ||... ..||| | |.|| |.|   .|. ...   . .|.   .. .|||||||..   |.|       |||||.|
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINV---MKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGC---GILYIVMEYC
Kinase PEK-S1_r.AA PEK 106-182 31 4.9e-16 51.65 In-house 1-90 (655) Show / Hide 
Range on Protein: 106-182
Range on HMM: 1-90/655
Sequence Identity: 31% (28 aa)

YEVLACVGQGAS-GKVYKCRSKEDEQIYAIKVIKVRTATKS------------RDQDVALVFKEGEMFQRCEHPNIVKYFDMWKEEGEPG
.|...|.|.|.  | |||...| |.. |||| ||.  ....             .   . |..|   . |..||||| |. .| |. | .
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARLNHPNIVRYHNAWIEKPEEK
Kinase PEK-S1_r.AA HRI 106-178 36 8.9e-14 44.21 In-house 1-70 (613) Show / Hide 
Range on Protein: 106-178
Range on HMM: 1-70/613
Sequence Identity: 36% (27 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVIKVRTATKSRDQDVALVFKEGEMFQRCEHPNIVKYFDMWKEE
.| .. .|.|  |.||| | | | | |||| ||.. .||    ..  .  |       .|.||| |   | |.
FEQKEIIGKGGYGRVYKVRHKLDKQHYAIKKIKIKKRTKC---SCMKMQREVKVLACLQHHNIVRYHQAWIEH
Kinase PEK-S1_r.AA TyrKc 106-364 17 1.4e-09 -67.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 106-364
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

YEVLACVGQGASGKVYKCRSKEDEQIYAIKVIKVRTATKSRDQDVALVFKEGEMFQRC--EHPNIVKYFDMWKEEGEPGK---SKVYIVMEFC-GRSLQS
 . .   | || |.|||.. |   .  |.|..|  .        ..   .| ..  .   .|||||. .    ..|.        ..||||.. . .|..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKD

VLLGGESPPADAFRQLLQAVAHV*VGFMVWPISHDNVGVHGDIAPHNIFVTDDGRIKLGDFGLAKNKESM----LTTENIKK-----GR-----------
 |   .       ..||.    .  | |   ... |. .| |.|  |. |......| .||||... ..       .. ..|     |.           
YLRKHRPK--LCMKDLLSFCWQIACG-MEY-LHSKNC-IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

AVYSSPQRRSNSTYTDMLALGVILFELHWRCPPDQER--------ESVLIDVRDGFLPADWAY--------QHPSIAPKVLELVAARRDQRPSAHDILCD
.     . .  .| .|  . || ..|.  .. .  .         . |. .|..|. .   ..         .. .    ..  ..  ..||.  .|  .
CI----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

P
 
F
Kinase PEK-S1_r.AA NEK 241-264 46 1.1e-07 23.52 In-house 144-171 (286) Show / Hide 
Range on Protein: 241-264
Range on HMM: 144-171/286
Sequence Identity: 46% (13 aa)

DIAPHNIFVTDDGR----IKLGDFGLAK
|| | ||| |....    .|.||||..|
DIKPQNIFLTKNNNDYHNVKIGDFGISK
Kinase PEK-S1_r.AA HRI 295-366 36 2e-06 17.69 In-house 542-613 (613) Show / Hide 
Range on Protein: 295-366
Range on HMM: 542-613/613
Sequence Identity: 36% (26 aa)

DMLALGVILFELHWRCPPDQERESVLIDVRDGFLPADWAYQHPSIAPKVLELVAARRDQRPSAHDILCDPAW
||  .|||||||      . ||  ||  || | .|       |  |  .  |      |||||  .|    .
DMYSMGVILFELFQPFGTEMERAEVLTGVRTGQIPESLRKRCPVQAKYIQHLTRRNASQRPSAIQLLQSELF
Kinase PEK-S1_r.AA CMGC 238-264 27 3e-06 15.66 In-house 206-252 (513) Show / Hide 
Range on Protein: 238-264
Range on HMM: 206-252/513
Sequence Identity: 27% (13 aa)

VHGDIAPHNIFVTDD--------------------GRIKLGDFGLAK
.| |. | || ....                    ||.|..|||||.
IHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLAR
Kinase PEK-S1_r.AA CAMK 238-272 17 8e-06 13.92 In-house 201-278 (425) Show / Hide 
Range on Protein: 238-272
Range on HMM: 201-278/425
Sequence Identity: 17% (14 aa)

VHGDIAPHNIFVTDD-----------------GRIKLGDFGLAKNKES--------------------------MLTT
|| |. | || ..|.                 . ||. |||.|. ...                          ...|
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKT
Kinase PEK-S1_r.AA NEK1 239-264 34 9e-06 16.2 In-house 127-169 (276) Show / Hide 
Range on Protein: 239-264
Range on HMM: 127-169/276
Sequence Identity: 34% (15 aa)

HGDIAPHNIFVT--DDG---------------RIKLGDFGLAK
| || . ||| |  ..|                .|||||| |.
HRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIAR
Kinase PEK-S1_r.AA Pkinase_Tyr 106-193 26 8.6e-05 16.85 Pfam 1-89 (270) Show / Hide 
Range on Protein: 106-193
Range on HMM: 1-89/270
Sequence Identity: 26% (25 aa)

YEVLACVGQGASGKVYKCRSK----EDEQIYAIKVIKVRTATKSRDQD--VALVFKEGEMFQRC-EHPNIVKYFDMWKEEGEPGKSKVYIVMEFC
 . .   |.|| |.|||.. |    ....  |.|..|     .. ...   .  ..| ..      |||||..     ..|||.  ..|||||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYM
Kinase PEK-S1_r.AA Pkinase 244-264 48 0.000113 17.61 Pfam 136-160 (293) Show / Hide 
Range on Protein: 244-264
Range on HMM: 136-160/293
Sequence Identity: 48% (12 aa)

PHNIFVTDDGRI----KLGDFGLAK
| ||.. ..| |    |..||||||
PENILIDNNGHIDACVKICDFGLAK
Kinase PEK-S1_r.AA Pkinase_Tyr 238-264 44 0.00015 16.03 Pfam 133-159 (270) Show / Hide 
Range on Protein: 238-264
Range on HMM: 133-159/270
Sequence Identity: 44% (12 aa)

VHGDIAPHNIFVTDDGRIKLGDFGLAK
.| |.|  |. ||... .| .|||||.
IHRDLAARNCLVTENNVVKICDFGLAR
Kinase PEK-S1_r.AA HRI 238-263 50 0.000229 10.29 In-house 455-484 (613) Show / Hide 
Range on Protein: 238-263
Range on HMM: 455-484/613
Sequence Identity: 50% (15 aa)

VHGDIAPHNIFVTDDGR----IKLGDFGLA
|| |. | |||  |       .| ||||||
VHRDVKPRNIFLHDPDQGHPQVKIGDFGLA
Kinase PEK-S1_r.AA STE 238-265 39 0.000529 10.17 In-house 174-196 (359) Show / Hide 
Range on Protein: 238-265
Range on HMM: 174-196/359
Sequence Identity: 39% (11 aa)

VHGDIAPHNIFVTDDGRIKLGDFGLAKN
.| || | ||..     .|| |||....
IHRDIKPANILL-----VKLCDFGVCGQ
Kinase PEK-S1_r.AA STE20 238-263 50 0.0014 9.3 In-house 139-164 (288) Show / Hide 
Range on Protein: 238-263
Range on HMM: 139-164/288
Sequence Identity: 50% (13 aa)

VHGDIAPHNIFVTDDGRIKLGDFGLA
.| ||   || .|.||..|| |||..
IHRDIKADNILLTEDGEVKLADFGVC
Kinase PEK-S1_r.AA NEK 352-366 46 0.062409 3.06 In-house 272-286 (286) Show / Hide 
Range on Protein: 352-366
Range on HMM: 272-286/286
Sequence Identity: 46% (7 aa)

DQRPSAHDILCDPAW
.||||. .|| .|  
EQRPSCNQILEMPFI
Kinase PEK-S1_r.AA NEK1 354-366 46 0.091281 2.11 In-house 264-276 (276) Show / Hide 
Range on Protein: 354-366
Range on HMM: 264-276/276
Sequence Identity: 46% (6 aa)

RPSAHDILCDPAW
|||...||. |  
RPSVNQILERPFI