RHOK_Hsap_GRK FLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILMKVH---
GPRK7_Hsap_GRK FTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVS---
GPRK6_Hsap_GRK FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVN---
GPRK5_Hsap_GRK FRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVN---
GPRK4_Hsap_GRK FRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQ---
Gprk1_Dmel_BARK FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGEMLALNERNMLQAVSTGI
Gprk2_Dmel_GRK FRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKIN---
GPRK6_Mmus_GRK FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVN---
GPRK5_Mmus_GRK FRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVN---
GPRK4_Mmus_GRK FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKRILEKLH---
BARK2_Mmus_BARK FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALNERIMLSLVSTG-
BARK1_Mmus_BARK FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTG-
F19C6.1_Cele_GRK FRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLNEKQILQRIN---
BARK1_Hsap_BARK FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTG-
BARK2_Hsap_BARK FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTG-
RHOK_Mmus_GRK FLDFRVLGKGGFGEVSACQMKATGKMYACKKLNKKRLKKRKGYQGAIVEKRILTKVH---
W02B3.2_Cele_BARK FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQ
BARK_Spur_BARK FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKSGETLALNERIMLSLVSET-
GPRK_Spur_GRK ------------------------------------------------------------
AqueK007_Aque_BARK FNVHRIIGRGGFGEVFGCRKDDSGKMFAMKLLDKKRIKVKRGELLALNERNMLAKVN---
AqueK008_Aque_GRK FRQYRVLGKGGFGLVFACQSKFTGKMYALKKLEKKRVKKRKGEKLALNEKEVLEKVD---
RHOK_Hsap_GRK -SRFIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQIICGL
GPRK7_Hsap_GRK -SPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVG--TRGLDMSRVIFYSAQIACGM
GPRK6_Hsap_GRK -SRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMG--QAGFPEARAVFYAAEICCGL
GPRK5_Hsap_GRK -SQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMG--NPGFEEERALFYAAEILCGL
GPRK4_Hsap_GRK -SRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLG--NPGFDEQRAVFYAAELCCGL
Gprk1_Dmel_BARK DCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHG----IFSEDEMKFYAAEVILGL
Gprk2_Dmel_GRK -SPFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGG-EPGFELERARFYAAEVACGL
GPRK6_Mmus_GRK -SRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMG--QAGFPEARAVFYAAEICCGL
GPRK5_Mmus_GRK -SQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMG--NPGFEEERALFYAAEILCGL
GPRK4_Mmus_GRK -SRFVVSLAYTYETKDALCLVLTIMNGGDLKYHIYNLG--DPGFEEPRAVFYAAELCCGL
BARK2_Mmus_BARK DCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHG----VFSEKEMRFYASEIILGL
BARK1_Mmus_BARK DCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHG----VFSEADMRFYAAEIILGL
F19C6.1_Cele_GRK -SPFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLM--PGGFDEKRVQFYAAEITLGL
BARK1_Hsap_BARK DCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHG----VFSEADMRFYAAEIILGL
BARK2_Hsap_BARK DCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHG----VFSEKEMRFYATEIILGL
RHOK_Mmus_GRK -SRFIVSLAYAFETKTDLCLVMTIMNGGDVRYHIYNVDEDNPGFSEPRAIYYTAQIISGL
W02B3.2_Cele_BARK DCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHG----VFTEQEMIFYASEVILGL
BARK_Spur_BARK DCPFIVCMTYAFQTPDKLCFILDLMNGGDLHYHLSQHG----VFSEEEVGFYAAEIILGL
GPRK_Spur_GRK --------------KEALCLVLTIMNGGDLKFHIHNMG--SPGFEEERARFYAAEILCGL
AqueK007_Aque_BARK -SPFVVNLYYAFQTPEKLCFILDLMNGGDLHYHLTQHG----VFNEAEVRFYAAELILAL
AqueK008_Aque_GRK -SRFVVTLAYAYQSKDSLCMVLTLMNGGDLRFHIYSIG--SPGLEPERVVFYAAEIACGL
*.::: :*****:::*: : :*:::: .:
RHOK_Hsap_GRK EHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTPGFMAPELLQ
GPRK7_Hsap_GRK LHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGK-PITQRAGTNGYMAPEILM
GPRK6_Hsap_GRK EDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQ-TIKGRVGTVGYMAPEVVK
GPRK5_Hsap_GRK EDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGD-LIRGRVGTVGYMAPEVLN
GPRK4_Hsap_GRK EDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQ-RVRGRVGTVGYMAPEVVN
Gprk1_Dmel_BARK EHMHKRCIVYRDLKPANILLDENGHIRISDLGLACDFSKKK--PHASVGTHGYMAPEVLS
Gprk2_Dmel_GRK QHLHKQGIVYRDCKPENILLDDHGHVRISDLGLAVEIPEGE-MVRGRVGTVGYMAPEVID
GPRK6_Mmus_GRK EDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQ-TIKGRVGTVGYMAPEVVR
GPRK5_Mmus_GRK EDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGD-LIRGRVGTVGYMAPEVLN
GPRK4_Mmus_GRK EDLQRKRIVYRDLKPENILLDDHGHIRISDLGLAMEVPEGE-MVRGRVGTVGYMAPEIIN
BARK2_Mmus_BARK EHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKKK--PHASVGTHGYMAPEVLQ
BARK1_Mmus_BARK EHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKR--PHASVGTHGYMAPEVLQ
F19C6.1_Cele_GRK QHLHSERILYRDLKPENILLDDFGHVRISDLGLAVEIKDNE-PIKGRVGTVGYMAPEIVK
BARK1_Hsap_BARK EHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKK--PHASVGTHGYMAPEVLQ
BARK2_Hsap_BARK EHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKK--PHASVGTHGYMAPEVLQ
RHOK_Mmus_GRK EHLHQRRIVYRDLKPENVLLDNDGNIRISDLGLAVELKEGQNKTKGYAGTPGFMAPELLR
W02B3.2_Cele_BARK EHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKKK--PHASVGTHGYMAPEVLA
BARK_Spur_BARK EHMHVRNVVYRDLKPANILLDENGHVRISDLGLACDFSSKK--PHASVGTHGYMAPEVLS
GPRK_Spur_GRK EDLHRLRIVYRDMKPENILLDDHGHVRISDLGLAVEIPEND-TIRGRVGTVGYMAPEVVK
AqueK007_Aque_BARK EHIHSQLIVYRDLKPSNVLLDEAGHIRLSDLGLACEFSDRK--PSSCVGTHGYMAPEVIQ
AqueK008_Aque_GRK HHLHTARIAYRDMKPDNILLDDAGHIRISDLGLAVHIPEGQ-SVRGRVGTPGYMAPEVID
.:: *** ** *:***: *: *:****** . .** *:****::
RHOK_Hsap_GRK -------------------------------------GEEYDFSVDYFALGVTLYEMIAA
GPRK7_Hsap_GRK E------------------------------------KVSYSYPVDWFAMGCSIYEMVAG
GPRK6_Hsap_GRK -------------------------------------NERYTFSPDWWALGCLLYEMIAG
GPRK5_Hsap_GRK -------------------------------------NQRYGLSPDYWGLGCLIYEMIEG
GPRK4_Hsap_GRK -------------------------------------NEKYTFSPDWWGLGCLIYEMIQG
Gprk1_Dmel_BARK K------------------------------------GTSYDSCADWFSFGCMLYKLLKG
Gprk2_Dmel_GRK -------------------------------------NEKYAFSPDWFSFGCLLYEMIEG
GPRK6_Mmus_GRK -------------------------------------NERYTFSPDWWALGCLLYEMIAG
GPRK5_Mmus_GRK -------------------------------------NQRYGLSPDYWGLGCLIYEMIEG
GPRK4_Mmus_GRK -------------------------------------HEKYTFSPDWWGLGCLIYEMIAG
BARK2_Mmus_BARK K------------------------------------GTCYDSSADWFSLGCMLFKLLRG
BARK1_Mmus_BARK K------------------------------------GVAYDSSADWFSLGCMLFKLLRG
F19C6.1_Cele_GRK -------------------------------------NERYSYGVDWWGVGCLIYEMIEG
BARK1_Hsap_BARK K------------------------------------GVAYDSSADWFSLGCMLFKLLRG
BARK2_Hsap_BARK K------------------------------------GTAYDSSADWFSLGCMLFKLLRG
RHOK_Mmus_GRK -------------------------------------GEEYDFSVDYFALGVTLYEMIAA
W02B3.2_Cele_BARK K------------------------------------GVAYDSSADWFSLGCMLYKLLKG
BARK_Spur_BARK KGTAYDSSADWFSLGCMLFKLLHGGTHGYMAPEVLSKGTAYDSSADWFSLGCMLFKLLHG
GPRK_Spur_GRK -------------------------------------NERYTFSPDYWGLGCLIYEMIEG
AqueK007_Aque_BARK K------------------------------------GVHYDKSADWFSLGCVLYKLLRG
AqueK008_Aque_GRK -------------------------------------GHRYTFAPDWWGMGCLIYEMICG
* *::..* ::::: .
RHOK_Hsap_GRK RGPFRARGEKVENKELKHRIISEPVKYP-DKFSQASKDFCEALLEKDPEKRLGFRDE---
GPRK7_Hsap_GRK RTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKDICRLFLAKKPEQRLGSREK---
GPRK6_Hsap_GRK QSPFQQRKKKIKREEVERLVKEVPEEYS-ERFSPQARSLCSQLLCKDPAERLGCRGG---
GPRK5_Hsap_GRK QSPFRGRKEKVKREEVDRRVLETEEVYS-HKFSEEAKSICKMLLTKDAKQRLGCQEE---
GPRK4_Hsap_GRK HSPFKKYKEKVKWEEVDQRIKNDTEEYS-EKFSEDAKSICRMLLTKNPSKRLGCRGE---
Gprk1_Dmel_BARK HSPFRQHKTKDK-LEIDKMTLTMNVEL-PESFSLELKNLLEMLLQRDVSKRLGCMGN---
Gprk2_Dmel_GRK QAPFRMRKEKVKREEVDRRVKEDPEKYS-SKFNDEAKSMCQQLLAKSIKQRLGCRNGR--
GPRK6_Mmus_GRK QSPFQQRKKKIKREEVERLVKEVAEEYT-DRFSSQARSLCSQLLSKDPAERLGCRGG---
GPRK5_Mmus_GRK QSPFRGRKEKVKREEVDRRVLETEEVYS-SKFSEEAKSICNMLLTKDSKQRLGCQEE---
GPRK4_Mmus_GRK HSPFRKYKEKVNREELERRVKNETEEYS-ERFSEDAKSICSMLLIKDPSKRLGCQRD---
BARK2_Mmus_BARK HSPFRQHKTKDK-HEIDRMTLTVNVQL-PDAFSPELRSLLEGLLQRDVSQRLGCGGG---
BARK1_Mmus_BARK HSPFRQHKTKDK-HEIDRMTLTMAVEL-PDSFSPELRSLLEGLLQRDVNRRLGCLGR---
F19C6.1_Cele_GRK KAPFRQRKEKVKREEVERRVREDQEKYS-EKFSEAARTLCRGLLHKEPGFRLGCRRVGRP
BARK1_Hsap_BARK HSPFRQHKTKDK-HEIDRMTLTMAVEL-PDSFSPELRSLLEGLLQRDVNRRLGCLGR---
BARK2_Hsap_BARK HSPFRQHKTKDK-HEIDRMTLTVNVEL-PDTFSPELKSLLEGLLQRDVSKRLGCHGG---
RHOK_Mmus_GRK RGPFRARGEKVENKELKQRIISEPVKYP-EKFSQASKDFCEQLLEKDPEKRLGFRDG---
W02B3.2_Cele_BARK HSPFRQHKSKDK-NEIDKMTLTQDIELPNEGLSKDCRDLLEGLLKRDVPDRLGCRGK---
BARK_Spur_BARK HSPFRQHKTKDK-HEIDRMTLTMDVEF-PDKMSDEMRALLAGLLQREVASRLGCEGR---
GPRK_Spur_GRK RAPFRARKEKVKREEVDRRVKEDDEKYS-QKFSTEAQDICKKLLQKDPALRMGFEN----
AqueK007_Aque_BARK HSPFRSQ---NK-DEVDQITLTKEVTM-PSSFSPGVSQLLTGLLEKDPTKRLGCLDT---
AqueK008_Aque_GRK RTPFRKHKERVSREDIERRIKDDRVCLDNSAFTEDSRSICDQFLDKVHATRLGCCGE---
: **: . ::.: :. : :* : *:*
RHOK_Hsap_GRK --TCDKLRAHPLF
GPRK7_Hsap_GRK ---SDDPRKHHFF
GPRK6_Hsap_GRK --SAREVKEHPLF
GPRK5_Hsap_GRK --GAAEVKRHPFF
GPRK4_Hsap_GRK --GAAGVKQHPVF
Gprk1_Dmel_BARK --GADEVKMHNFF
Gprk2_Dmel_GRK -MGGQDVMAHPFF
GPRK6_Mmus_GRK --GAREVKEHPLF
GPRK5_Mmus_GRK --GAAEVKRHPFF
GPRK4_Mmus_GRK --GVSAVKQHPIF
BARK2_Mmus_BARK --GARELKEHIFF
BARK1_Mmus_BARK --GAQEVKESPFF
F19C6.1_Cele_GRK EDGAEEIRAHPFF
BARK1_Hsap_BARK --GAQEVKESPFF
BARK2_Hsap_BARK --GSQEVKEHSFF
RHOK_Mmus_GRK --TCDALRANVLF
W02B3.2_Cele_BARK --GPTEVKEHPFF
BARK_Spur_BARK --GATEVREHPFF
GPRK_Spur_GRK -GTAQTVKDHSFF
AqueK007_Aque_BARK --GVDAIKELPFF
AqueK008_Aque_GRK --MFEDVKAHPFF
.*