GSK3B_Hsap YTDTKVIGNGSFGVVYQAK-------------LC---DSG----ELVAIKKVLQDKRFKN
GSK3A_Hsap YTDIKVIGNGSFGVVYQAR-------------LA---ETR----ELVAIKKVLQDKRFKN
Pk34A_Dmel IEVKDLIGSGSFGRVYQAH-------------VN---ESE----EIVAVKQTLYNPKLSQ
sgg_Dmel YTDTKVIGNGSFGVVFQAK-------------LC---DTG----ELVAIKKVLQDRRFKN
gskt_Dmel YTDAKVVGNGSFGVVFQAK-------------MV---PSN----EMVAIKKVLQDRRFKN
GSK3B_Mmus YTDTKVIGNGSFGVVYQAK-------------LC---DSG----ELVAIKKVLQDKRFKN
GSK3A_Mmus YTDIKVIGNGSFGVVYQAR-------------LA---ETR----ELVAIKKVLQDKRFKN
R03D7.5_Cele ISAHKLCGSGRFSNVYCGQ-------------MI---SP-IE--KEVAVKNVWSDTETRH
F21F3.2_Cele IEEVHLHSCGVFSNVYKGI-------------LR---EP-YE--KKIAIKKSWPEKGERN
C44H4.6_Cele FTNLQLIGTGSFGAVYKAV-------------LR---END----EPIAIKKIKVDDRFKS
C36B1.10_Cele LQNMNLFASGAFSNVYRGI-------------ART--ESNHQ--MEIVIKKTWPRHKGCP
RIM11_Scer FPTTEVVGHGSFGVVFATV-------------IQ---ETN----EKVAIKKVLQDKRFKN
MRK1_Scer YPTTEVVGHGSFGVVVTTV-------------II---ETN----QKVAIKKVLQDRRYKN
MCK1_Scer VKEYRKIGRGAFGTVVQAY-------------LT---QDKKNWLGPFAIKKVPAHTEYKS
Y106G6D.4_Cele MANLRLHARGVFSNVYRGT-------------IL---SPGTE--QEIAIKKTWPKTPYRN
Y106G6E.1_Cele LHHMNLFATGAFSNVYRGV-------------AQT--ESNQE--IDIVIKKTWPRHKGCP
Y18D10A.5_Cele YYDQKVIGNGSFGVVFLAK-------------LS---TTN----EMVAIKKVLQDKRFKN
YOL128C_Scer VREGKRIGHGSFGTVTQSI-------------LS---SNSIEWLGPYAIKRVVKSPKVQS
GlkA_Ddis YEIIKQVGQGTFGKVYEAK-------------NQ---D-N----KRVAIKKVEKSNHFIS
GSK-3_Ddis YITEGVIGNGSFGVVTQAI-------------VA---DTK----EVVAIKKVLQDQRYKN
19912_Tthe IDENNKIGQGNFGVVFKAE-------------FK---DTK----EEVAVKRVLQDKNFKN
19923_Tthe -------------------------------------ETG----ETVAIKKVFQDRRYKN
19924_Tthe GDEDKVVGSGTFGVVYQAT-------------TK---ETG----EVVAIKKVFQDKRYKN
2636_Tthe YEIKRVIGSGSFGYVFEAY-------------DN---NNQ----RTVALKRIQKVGKKLS
5825_Tthe ITLDKIIGNGTFGVVYLAK-------------MN---DTQ----EQVAIKKVFQDKRYKN
7876_Tthe LKIIDVVGNGTFGVVYKKLDDNINFNYLKMKALL---NKE----QVVAVKRVFQDKRYKN
GSK3_Spur YTDTRVIGNGSFGVVYQAR-------------MV---DSS----DLVAIKKVLQDKRFKN
n1163_Tthe ITLDKIIGNGTFGVVYLAK-------------MN---DTQ----EQVAIKKVFQDKRYKN
CC1G_03802_Ccin YTNCKVIGNGSFGVVFQAR-------------LLGVPKDQ----EDIAIKKVLQDKRFKN
AqueK117_Aque YTDLKVIGSGSFGVVYQAK-------------IL---ETN----EPIAIKKVLQDKRFKQ
GSK_b_Smoe YVAERVVGTGSFGIVFQAK-------------CL---ETG----ETVAIKKVLQDKRYKN
GSK_a-2_Smoe YVAERVVGTGSFGIVFQAK-------------CL---ETG----ETVAIKKVLQDKRYKN
GSK_a-1_Smoe YVAERVVGTGSFGIVFQAK-------------CL---ETG----ETVAIKKVLQDKRYKN
GK035_Glam FTTMRTIGSGSFGVVFIAK-------------T----STG----ELIAIKKVFQDRKYRN
GK036_Glam VVPEKVIGKGSFGVVYLVK-------------SL---KGN----TPLALKLVLQDRRYKN
.:*
GSK3B_Hsap ------RELQIM---RKL-DHCNIVRLR-YFFYSSGE------K----------------
GSK3A_Hsap ------RELQIM---RKL-DHCNIVRLR-YFFYSSGE------K----------------
Pk34A_Dmel ------GEAEIM---GQLKDHNNIVRLI-MHSSVSLG------F----------------
sgg_Dmel ------RELQIM---RKL-EHCNIVKLL-YFFYSSGE------K----------------
gskt_Dmel ------RELQIM---RKL-RHDNIITLK-WFFFSSGE------K----------------
GSK3B_Mmus ------RELQIM---RKL-DHCNIVRLR-YFFYSSGE------K----------------
GSK3A_Mmus ------RELQIM---RKL-DHCNIVRLR-YFFYSSGE------K----------------
R03D7.5_Cele LATSEYPEIQIL---SKL-FHPAISNLL-YFYSRNAND----------------------
F21F3.2_Cele ------FEFIFLTGRERA-KHKNVIHMI-FAFSHSYDT----------------------
C44H4.6_Cele ------RELTIM---HEM-DHPNIIRLL-YYYVM--------------------------
C36B1.10_Cele ------LEVKILGKLGKL-KHKNIVRLL-FSYQKQ--------H----------------
RIM11_Scer ------RELEIM---KML-SHINIIDLK-YFFYERD-------S----------------
MRK1_Scer ------RELETM---KML-CHPNTVGLQ-YYFYEKD-------E----------------
MCK1_Scer ------RELQIL---RIA-DHPNIVKLQ-YFFTHLSP------Q----------------
Y106G6D.4_Cele ------FELLFLSGLRRK-PHKNIVQML-FAFSRNTTSGEGLEM----------------
Y106G6E.1_Cele ------MEVKILGQLGKL-KHRNIVRLL-YSYQKQ--------H----------------
Y18D10A.5_Cele ------RELQIM---RKL-NHPNIVKLK-YFFYSSGE------K----------------
YOL128C_Scer ------LELEIL---QNI-RHPNLVTLE-FFFESHCT------T----------------
GlkA_Ddis ------REYDIL---KIVA-HPNCLRIL-DMFYTAE-------D----------------
GSK-3_Ddis ------RELQIM---KML-NHINIVSLK-NSFYTS--------D----------------
19912_Tthe ------RELQIM---QEVAHHPNIVQLK-YSFYSFGE------E----------------
19923_Tthe ------RELQIM---KEIGNHPNVISLR-NYFYIYADD-----K----------------
19924_Tthe ------RELQMM---KEIGNHPNVIKLR-NHYYSYG-N-----S----------------
2636_Tthe ------REYEIL---LDIKDCDYVVKMI-DLYYSKT-------D----------------
5825_Tthe ------REFEII---KSL-NHQNLIKLK-QAYYTTQNN-----N----------------
7876_Tthe ------REREII---ERL-DHQNIIKCK-DFFETKGE------K----------------
GSK3_Spur ------RELQIM---RRL-DHHNIVKLK-YFFYSSGE------K----------------
n1163_Tthe ------REFEII---KSL-NHQNLIKLK-QAYYTTQNN-----NVDSFFFHTFNSKINSQ
CC1G_03802_Ccin ------RELQIM---RLV-SHPNVVDLK-AFFYSNGD------K----------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------RELQIM---RLL-DHPSIVSLK-HCFFSTT-------D----------------
GSK_a-2_Smoe ------RELQIM---RLL-DHPNIVALK-HCFFSTT-------D----------------
GSK_a-1_Smoe ------RELQIM---RLL-DHPNIVALK-HCFFSTT-------D----------------
GK035_Glam ------RELSIM---QELGQHPCIIRLI-NSYISVATN-----Q----------------
GK036_Glam ------REFQIM---RTL-VHPCICRLVKGTFIPSIS------S----------------
GSK3B_Hsap ------------------------------------------------------------
GSK3A_Hsap ------------------------------------------------------------
Pk34A_Dmel ------------------------------------------------------------
sgg_Dmel ------------------------------------------------------------
gskt_Dmel ------------------------------------------------------------
GSK3B_Mmus ------------------------------------------------------------
GSK3A_Mmus ------------------------------------------------------------
R03D7.5_Cele ------------------------------------------------------------
F21F3.2_Cele ------------------------------------------------------------
C44H4.6_Cele ------------------------------------------------------------
C36B1.10_Cele ------------------------------------------------------------
RIM11_Scer ------------------------------------------------------------
MRK1_Scer ------------------------------------------------------------
MCK1_Scer ------------------------------------------------------------
Y106G6D.4_Cele ------------------------------------------------------------
Y106G6E.1_Cele ------------------------------------------------------------
Y18D10A.5_Cele ------------------------------------------------------------
YOL128C_Scer ------------------------------------------------------------
GlkA_Ddis ------------------------------------------------------------
GSK-3_Ddis ------------------------------------------------------------
19912_Tthe ------------------------------------------------------------
19923_Tthe ------------------------------------------------------------
19924_Tthe ------------------------------------------------------------
2636_Tthe ------------------------------------------------------------
5825_Tthe ------------------------------------------------------------
7876_Tthe ------------------------------------------------------------
GSK3_Spur ------------------------------------------------------------
n1163_Tthe LRFFLRYKKTQNCLHSLIQFTRYIQKHSKKSNTKTLIQIFNLRELDFPASHPVFYTNPIL
CC1G_03802_Ccin ------------------------------------------------------------
AqueK117_Aque ------------------------------------------------------------
GSK_b_Smoe ------------------------------------------------------------
GSK_a-2_Smoe ------------------------------------------------------------
GSK_a-1_Smoe ------------------------------------------------------------
GK035_Glam ------------------------------------------------------------
GK036_Glam ------------------------------------------------------------
GSK3B_Hsap --------KDE--VY-LNLVLDYVPETVYRVARHYSR-------AKQTLPVIYVKLYMYQ
GSK3A_Hsap --------KDE--LY-LNLVLEYVPETVYRVARHFTK-------AKLTIPILYVKVYMYQ
Pk34A_Dmel --------PSV--DY-VLLVMEYMPMTLLDYINYHLTV------LQPAERLINVRILSYQ
sgg_Dmel --------RDE--VF-LNLVLEYIPETVYKVARQYAK-------TKQTIPINFIRLYMYQ
gskt_Dmel --------RDE--VY-LNLVMEFLPETLYKVERQYAR-------AKQTLPVNFVRLYMYQ
GSK3B_Mmus --------KDE--VY-LNLVLDYVPETVYRVARHYSR-------AKQTLPVIYVKLYMYQ
GSK3A_Mmus --------KDE--LY-LNLVLEYVPETVYRVARHFTK-------AKLITPIIYIKVYMYQ
R03D7.5_Cele ----------K--VI-NCLVLDYLPQDLARLRDQ-----------GVKFDVLDAKLYTFQ
F21F3.2_Cele ----------K--VC-ESYVFDFMPNTLAEVIR-------------QKLTDLDIRLYTWQ
C44H4.6_Cele --------QQE--NC-LNFVMEFMPKDLAYVHRQFAH-------NDKQMPAYSIKLYMFQ
C36B1.10_Cele --------EGR--IC-LGLIFEYIPMNLHQFLKDNN----------RRVDIIEVKLIVWQ
RIM11_Scer --------QDE--IY-LNLILEYMPQSLYQRLRHFVH-------QRTPMSRLEIKYYMFQ
MRK1_Scer --------EDE--VY-LNLVLDYMPQSLYQRLRHFVN-------LKMQMPRVEIKFYAYQ
MCK1_Scer --------DNK--VY-QHLAMECLPETLQIEINRYVT-------NKLEMPLKHIRLYTYQ
Y106G6D.4_Cele --------KHS--FC-ESYVFGFMPYTLQNILKK------------TRLAEVDMKLYTWQ
Y106G6E.1_Cele --------EGR--IC-LALIFEYIPLNLYQFLKDKN----------RRIDIVEVKLIVWQ
Y18D10A.5_Cele --------KDE--LY-LNLILEYVPETVYRVARHYSK-------QRQQIPMIYVKLYMYQ
YOL128C_Scer --------KDGGHLYQKNFVMEYIPQTLSSEIHEYFD-------NGSKMPTKHIKLYTFQ
GlkA_Ddis ---------NK--KM-QNLVFDFIPYTLASLLK------------KRQLSINFIKVLFYQ
GSK-3_Ddis --------NDE--VY-LNLVLEYVPDTVYRVSRHYSM-------SKQPVPNIFVKLYIYQ
19912_Tthe --------EDD--VY-LNLIMEYVPSNLTKMIKYYHRKKLKQFEQREQFPNILIKLYLYQ
19923_Tthe --------QED--VY-LNIIMDYIPETLYRMIKYFAKK------SKGNFPNILLKLYSYQ
19924_Tthe --------TDD--VY-LHLVMDFVPETLYKMIKYYSKK------HKGNFPNILLKYYSYQ
2636_Tthe --------DNK--LI-QNIVFEYMENNLEDHISKFNK-------SKKVIPEQTVKEYAYQ
5825_Tthe --------PDE--VY-LNIVMEYVPETLSKVIRTYRK-------SKQPFPPLLLKVFSYQ
7876_Tthe --------KDE--VY-LNLVMEFMNFPLSKVIRDKRK-------ANQVMRIEDIRLYAYQ
GSK3_Spur --------KDE--VF-LNLVLEYVPETVYRVARHYSK-------AKQTIANLYVKLYMYQ
n1163_Tthe TRRYSTVIPDE--VY-LNIVMEYVPETLSKVIRTYRK-------SKQPFPPLLLKVFSYQ
CC1G_03802_Ccin --------KDE--VY-LNLVLEYVPETVYRASRHYSK-------LKQPMPMLQIKLYMYQ
AqueK117_Aque --------KDE--VY-LNLVLDYIPDTVYRVIRHHYK-------AKQIMPMLFIKLYMYQ
GSK_b_Smoe --------KDE--LY-LNLVLEYVPETVYRIAKHYNR-------MNQRMPLLYVKLYTYQ
GSK_a-2_Smoe --------KDE--LY-LNLVLEYVPETVYRIAKHHNR-------MNQRMPLLYVKLYTYQ
GSK_a-1_Smoe --------KDE--LY-LNLVLEYVPETVYRIAKHHNR-------MNQRMPLLYVKLYTYQ
GK035_Glam --------TNG--DF-LNILMDYYQENGYQIYKSYIR-------AGIKMPMFHIKLYTFQ
GK036_Glam --------PDD--LI-LYLLMDYYPETIHSIYRQYSR-------LRQHVPLLIVRLITYQ
: : :*
GSK3B_Hsap LFRSLAYIHS-FGICHRDIKPQNLLLDPD--TAVLKLCDFGSAKQLVRG-----------
GSK3A_Hsap LFRSLAYIHS-QGVCHRDIKPQNLLVDPD--TAVLKLCDFGSAKQLVRG-----------
Pk34A_Dmel MFRGLGYLHL-LGISHRDVKPENLLIDNQ--KMVLKLSDFGSAKLLVPQ-----------
sgg_Dmel LFRSLAYIHS-LGICHRDIKPQNLLLDPE--TAVLKLCDFGSAKQLLHG-----------
gskt_Dmel LLRSMGYLHS-LGFCHRDIKPQNMLLDSE--TGVLKLCDFGSAKQLISG-----------
GSK3B_Mmus LFRSLAYIHS-FGICHRDIKPQNLLLDPD--TAVLKLCDFGSAKQLVRG-----------
GSK3A_Mmus LFRSLAYIHS-QGVCHRDIKPQNLLVDPD--TAVLKLCDFGSAKQLVRG-----------
R03D7.5_Cele LFCAISHLTS-KNIVHMDIKPQNVVMDRM--AGRLKLADFGNARRLETN-----------
F21F3.2_Cele IFSGLKYLEE-HKVVHRDLKPVNILVDHD--TAFLKISDFGSAKIIVKG-----------
C44H4.6_Cele LLRGIGFLHL-HNIVHRDIKPKNLLVDES--NGILKICDFGSAKRLEKN-----------
C36B1.10_Cele LFRGQAHLEK-SEICHRDIKPQNLLYNAD--TGLLKISDYGSSAIESVK-----------
RIM11_Scer LFKSLNYLHHFANVCHRDIKPQNLLVDPE--TWSLKLCDFGSAKQLKPT-----------
MRK1_Scer LFKALNYLHNVPRICHRDIKPQNLLVDPT--TFSFKICDFGSAKCLKPD-----------
MCK1_Scer IARGMLYLHG-LGVCHRDIKPSNVLVDPE--TGVLKICDFGSAKKLEHN-----------
Y106G6D.4_Cele LFEGIRYLQA-HMIVHRDIKPVNILVDVD--KGTLKIADFGSAKVVLRG-----------
Y106G6E.1_Cele LFRGQAHLEK-ADICHRDIKPQNLLYNAE--TGLLKISDFGSSSIQSTK-----------
Y18D10A.5_Cele LLRSLAYIHS-IGICHRDIKPQNLLIDPE--SGVLKLCDFGSAKYLVRN-----------
YOL128C_Scer ILRALLTLHS-MSICHGDLKPSNILIIPS--SGIAKVCDFGSAQRLDDN-----------
GlkA_Ddis LCQAIKHIHS-KAICHRDITPNNILLSS---KGELTLADFGSAKILESN-----------
GSK-3_Ddis LCRSINYIHS-LGICHRDIKPQNLLLDTS--TSTLKLCDFGSAKILIKG-----------
19912_Tthe AFRALAYLNG-LNIAHRDIKPSNILINHR--THQLKFCDFGSAKKLSRG-----------
19923_Tthe LMRSLAYIQG-LGICHRDIKPTNVLVDPR--NHALKMCDFGSAKKLNPS-----------
19924_Tthe MLRSLAYIHG-INICHRDIKPQNILVDPR--NHNLKMCDFGSAKKLVPG-----------
2636_Tthe ILKGLQYIHS-KGIAHRDLKPDNILLND---DGKVKICDFGGSKYIDEK-----------
5825_Tthe MFRALAYLKG-IGICHRDIKPQNILCDQK--TMQLKICDFGSAKKLIKG-----------
7876_Tthe MFKALSYLQS-LNICHRDIKPQNILVNDKDDDKRLKICDFGSAKQLIPN-----------
GSK3_Spur LFRSLAYIHS-MGICHRDIKPQNLLLNPE--TAVLKLCDFGSAKVLVRG-----------
n1163_Tthe MFRALAYLKG-IGICHRDIKPQNILCDQK--TMQLKICDFGSAKKLIKGKLDILFVSYSS
CC1G_03802_Ccin LLRSLAYIHS-VGICHRDIKPQNLLLNPS--TGVLKLCDFGSAKILVAG-----------
AqueK117_Aque LFRALGYIHA-NGVCHRDIKPQNLLLNPE--TGVLKLCDFGSAKVLVRG-----------
GSK_b_Smoe ICRALTYIHGGMGVCHRDIKPQNLLVNPH--THQLKLCDFGSAKVLVKG-----------
GSK_a-2_Smoe ICRSLAYIHGGIGVCHRDIKPQNLLVNPH--THQLKLCDFGSAKVLVKG-----------
GSK_a-1_Smoe ICRSLAYIHGGIGVCHRDIKPQNLLVNPH--THQLKLCDFGSAKVLVKG-----------
GK035_Glam FLRGLAYMHS-FNIANRDLKPQNTLVNRE--SGRAVLCDLGSAKKLNPA-----------
GK036_Glam LARSLAYLHY-HNIAHRDCKPTNVLIDPL--TYRCVLCDFGSAKQLVPQ-----------
. : . : * .* * : ..* *.:
GSK3B_Hsap ---------------------------------------------------EP-NVSYIC
GSK3A_Hsap ---------------------------------------------------EP-NVSYIC
Pk34A_Dmel ---------------------------------------------------EP-SISYIC
sgg_Dmel ---------------------------------------------------EP-NVSYIC
gskt_Dmel ---------------------------------------------------EP-NVSYIC
GSK3B_Mmus ---------------------------------------------------EP-NVSYIC
GSK3A_Mmus ---------------------------------------------------EP-NVSYIC
R03D7.5_Cele ---------------------------------------------------EKTGSAYQV
F21F3.2_Cele ---------------------------------------------------KA-NNFYQV
C44H4.6_Cele ---------------------------------------------------EP-NITYIC
C36B1.10_Cele ---------------------------------------------------TP-QQSYHV
RIM11_Scer ---------------------------------------------------EP-NVSYIC
MRK1_Scer ---------------------------------------------------QP-NVSYIC
MCK1_Scer ---------------------------------------------------QP-SISYIC
Y106G6D.4_Cele ---------------------------------------------------SS-STSYQV
Y106G6E.1_Cele ---------------------------------------------------SP-QQSYHV
Y18D10A.5_Cele ---------------------------------------------------EP-NVSYIC
YOL128C_Scer ---------------------------------------------------TE-LKTYFC
GlkA_Ddis ---------------------------------------------------HT-SMSYIC
GSK-3_Ddis ---------------------------------------------------ET-NVSYIC
19912_Tthe ---------------------------------------------------ES-NISYIC
19923_Tthe ---------------------------------------------------ET-NISYIC
19924_Tthe ---------------------------------------------------ES-NISYIC
2636_Tthe ---------------------------------------------------GK-NTPYIV
5825_Tthe ---------------------------------------------------EP-NVSYIC
7876_Tthe ---------------------------------------------------EA-NISYIC
GSK3_Spur ---------------------------------------------------EP-NVSYIC
n1163_Tthe VVSKNLVFILISSLTAKKQIDYQQFLFKSNKKPKQLLNIQTAPFNKHQKQSEP-NVSYIC
CC1G_03802_Ccin ---------------------------------------------------EP-NVSYIC
AqueK117_Aque ---------------------------------------------------EP-NVSYIC
GSK_b_Smoe ---------------------------------------------------EP-NISYIC
GSK_a-2_Smoe ---------------------------------------------------EP-NISYIC
GSK_a-1_Smoe ---------------------------------------------------EP-NISYIC
GK035_Glam ---------------------------------------------------EP-NIAYIC
GK036_Glam ---------------------------------------------------EN-NVAYIC
*
GSK3B_Hsap SRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLGTPT
GSK3A_Hsap SRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLGTPT
Pk34A_Dmel SRLYRAPELFAGYELYSCAVDIWSAGCVLAELLKGYPLFSSHKHDRKQLRLIVNMLGTDG
sgg_Dmel SRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEVIKVLGTPT
gskt_Dmel SRYYRAPELIFGSTDYTTKIDMWSAGCVMSELLLGQLIFPGD-SGVDQIVEIVKVMGTPT
GSK3B_Mmus SRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLGTPT
GSK3A_Mmus SRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLGTPT
R03D7.5_Cele TRFYRPPELLFGCEKFTASIDIWSATCVAFELFANRVLFKGK-DTKDQIVLITGVFGYPT
F21F3.2_Cele TRFYRPPELLMKAMEYNSTVDVWSAGCIMAEMVKRHVVFPGR-DSAHQLKLYCRCFGAPN
C44H4.6_Cele SRYYRAPELIFGSKNYDTSIDTWSVGTVVGELLHNSPIFLAD-SAVDILALQIKAFGTPS
C36B1.10_Cele TRYYRPPELLLGSKNYGCKIDTWSCGCVFGELLKGGIFLAGK-SAKNQAEVVFDMFGVPT
RIM11_Scer SRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGE-SGIDQLVEIIKILGTPS
MRK1_Scer SRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGE-SGIDQLVEIIKIMGIPT
MCK1_Scer SRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQ-EPLLQLREIAKLLGPPD
Y106G6D.4_Cele TRFYRPPELLLDAKEYYWMVDVWSAGCCVGEMMKGKVLFPGA-SIKIMLKLIVQAIGLPS
Y106G6E.1_Cele TRYYRPPELILGSKYYGCKIDTWSCGCVFGELLKGGIILAGK-SSNNQAEVIFDMLGYPT
Y18D10A.5_Cele SRYYRAPELIFGATNYTNSIDVWSAGTVMAELLLGQPIFPGD-SGVDQLVEIIKVLGTPT
YOL128C_Scer SRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKGD-SANSQLEEIAKLLGRFP
GlkA_Ddis SRYYRAPELLVGCSNYTTKIDIWSIGCILAEMLIGKPLFPGT-NSNDQLGRIIEVLGSPT
GSK-3_Ddis SRHYRAPELIFGSTNYTTTIDVWSLGCVLAELLLGQPLFPGE-NGIDQLVEIIKVLGTPT
19912_Tthe SRFYRAPELMLGASNYTTSVDVWSLGCVVAEMLLGEPLFKGN-SSLDQLV----------
19923_Tthe SRYYRAPELMFMATQYTNSIDVWSVGCVIAEMVLGDPIFAGE-SSVDQLIEIIKILGTPT
19924_Tthe SRCYRAPELMFQATQYTHAIDVWSVGCVIAEMVLGQPIFIGE-SSVDQLIEIIKVLGTPT
2636_Tthe SRYYRAPELILCITKYNQKIDMWSFGCILGELVTTFPLFQGK-TEGDQLFSIFKVLGSPT
5825_Tthe SRYYRAPELIFGAEQYTTAIDTWSIGTVIAEMILGEPLFPGE-NAVEQLVEIIKILGTPT
7876_Tthe SRYYRAPELIFKSQHYTNAIDMWSMGCVIAEMVLGEPLFPGE-NSLDQLVEIIRILGTPT
GSK3_Spur SRYYRAPELIFGATDYTCDIDVWSAGCVLAELLLGQPIFPGD-SGVDQLVEIIKVLGTPS
n1163_Tthe SRYYRAPELIFGAEQYTTAIDTWSIGTVIAEMILGEPLFPGE-NAVEQLVEIIKILGTPT
CC1G_03802_Ccin SRYYRAPELIFGATNYTTNIDIWSTGCVMAELMLGQPLFPGE-SGIDQLVEIIKVLGTPS
AqueK117_Aque SRYYRAPELIFGATDYTVNIDIWSAGCVFAELLLGQPIFPGD-SGVDQLVEIIKILGTPT
GSK_b_Smoe SRYYRAPELIFGATDYTTAIDIWSTGCVLAELLLGQPLFPGE-SGVDQLVEIIKVLGTPT
GSK_a-2_Smoe SRYYRAPELIFGATEYTTAIDIWSMGCVLAELLLGQPLFPGE-SGVDQLVEIIKVLGTPT
GSK_a-1_Smoe SRYYRAPELIFGATEYTTAIDIWSMGCVLAELLLGQPLFPGE-SGVDQLVEIIKVLGTPT
GK035_Glam SRYYRAPELIFGSRYYTTVIDIWSFGCVVAEMIIGKPIYAGS-SPLDQIIEIIKILGPPS
GK036_Glam SRFYRAPELVIGNQNYTCAIDIWSFGCIMAEILLGQPLFPGD-SSIDQLVEIVRVLGSPT
:* **.***. : :* *. *:. . .
GSK3B_Hsap REQIREMNPNYT--EFKF--------------------------P------QI-------
GSK3A_Hsap REQIREMNPNYT--EFKF--------------------------P------QI-------
Pk34A_Dmel LERAPEILSKCG--NSLH--------------------------P------RT-------
sgg_Dmel REQIREMNPNYT--EFKF--------------------------P------QI-------
gskt_Dmel SEQLHDMNPHYK--QFKL--------------------------P------EL-------
GSK3B_Mmus REQIREMNPNYT--EFKF--------------------------P------QI-------
GSK3A_Mmus REQIREMNPNYT--EFKF--------------------------P------QI-------
R03D7.5_Cele DDDIKSIGVKRP--RVARKD--ARGIETVKIKEKTNKTKKEAKQSTLVHEKYT-------
F21F3.2_Cele EQDISAMKGEKL--EKEYWK-------------------------------FT-------
C44H4.6_Cele KEDMAKWNYEYV--HIPY--------------------------D------TI-------
C36B1.10_Cele AEDVSSMNVSNT--KYKEIIQSY-------------------EPD------TSKRTADLA
RIM11_Scer KQEICSMNPNYM--EHKF--------------------------P------QI-------
MRK1_Scer KDEISGMNPNYE--DHVF--------------------------P------NI-------
MCK1_Scer KRFIFFSNPAYD--GPLFSK--P-------------------LFS------GS-------
Y106G6D.4_Cele ARDLDYMKVSSM--IDQQSA--------------------------------V-------
Y106G6E.1_Cele DSDVSSMKVSST--KLQEVLDSY-------------------EYN------KSKTTADLT
Y18D10A.5_Cele REQIQSMNPNYK--EFKF--------------------------P------QI-------
YOL128C_Scer KSSIKNSQELQ----DSLND--Q-------------------KFK---------------
GlkA_Ddis KDDMEAMKPSKP--YHL-------------------------QLP------NI-------
GSK-3_Ddis KEQIHAMNPYYT--SFKF--------------------------P------EI-------
19912_Tthe ------------------------------------------------------------
19923_Tthe LQQ--HMNPDHQ--PTQM--------------------------P------KI-------
19924_Tthe QQQIFAMNPDHQ--GTKM--------------------------P------NI-------
2636_Tthe KEEFQKFSERVPFDKKIFD-----------------------EFQ------TY-------
5825_Tthe KEQVQKMNPQHN--QFNF--------------------------P------SI-------
7876_Tthe RQQILMMNPTSQ--EFRF--------------------------P------QI-------
GSK3_Spur RDQIKEMNPNYT--EFKF--------------------------P------QI-------
n1163_Tthe KEQVQKMNPQHN--QFNF--------------------------P------SI-------
CC1G_03802_Ccin REQIKTMNPNYM--EHKF--------------------------P------QI-------
AqueK117_Aque KEQIRQMNPNYT--EFKF--------------------------P------QI-------
GSK_b_Smoe REEIKCMNPNYT--EFKF--------------------------P------QI-------
GSK_a-2_Smoe REEIKCMNPNYT--EFKF--------------------------P------QI-------
GSK_a-1_Smoe REEIKCMNPNYT--EFKF--------------------------P------QI-------
GK035_Glam LKELKEMNPTLK--EYAF--------------------------P------TI-------
GK036_Glam AEEFLAMNPTLK--SVKF--------------------------K------DV-------
GSK3B_Hsap -------------K--------AHPWTKDSSGTGHFTSGVRVFR----------------
GSK3A_Hsap -------------K--------AHPWTK-------------VFK----------------
Pk34A_Dmel -------------T--------RPSWNY-------------LLN----------------
sgg_Dmel -------------K--------SHPWQK-------------VFR----------------
gskt_Dmel -------------K--------PHPWSK-------------VFR----------------
GSK3B_Mmus -------------K--------AHPWTKDSPGAGHFTPGVRVFR----------------
GSK3A_Mmus -------------K--------AHPWTK-------------VFK----------------
R03D7.5_Cele -------------RARAMSRSTENKLAP-------------FTS----------------
F21F3.2_Cele -------------K--------GFGLQR-------------LVN----------------
C44H4.6_Cele -------------T--------GVGIQK-------------FIG----------------
C36B1.10_Cele YLYNQTASFQRDRR--------STVYNT-------------KID----------------
RIM11_Scer -------------K--------PIPLSR-------------VFK----------------
MRK1_Scer -------------K--------PITLAE-------------IFK----------------
MCK1_Scer -------------S--------QQRFEK-------------YFG----------------
Y106G6D.4_Cele -------------K--------VIGLKE-------------VLG----------------
Y106G6E.1_Cele YLYTQTVIYQKDRR--------TTVYNT-------------KIE----------------
Y18D10A.5_Cele -------------K--------AHPWNK-------------VFR----------------
YOL128C_Scer ------------------------KFMH-------------WFP----------------
GlkA_Ddis -------------N--------PKFFES--------------LH----------------
GSK-3_Ddis -------------K--------ANPWPR-------------VFK----------------
19912_Tthe ------------------------------------------------------------
19923_Tthe -------------K--------PTPWSK-------------VFK----------------
19924_Tthe -------------K--------PTPWTK-------------VFQ----------------
2636_Tthe -------------E--------PQNLRK-------------MFF----------------
5825_Tthe -------------K--------PTSWTK-------------IF-----------------
7876_Tthe -------------K--------SYSWSK-------------VFEKSLQ------------
GSK3_Spur -------------K--------PHPWNK-------------VFR----------------
n1163_Tthe -------------K--------PTSWTK-------------LIKQISTVINKYSNKKQQQ
CC1G_03802_Ccin -------------K--------PHPFSK-------------VFR----------------
AqueK117_Aque -------------K--------AHAWNK-------------VFR----------------
GSK_b_Smoe -------------K--------AHPWHK-------------VFH----------------
GSK_a-2_Smoe -------------K--------AHPWHK-------------VFH----------------
GSK_a-1_Smoe -------------K--------AHPWHK-------------VFH----------------
GK035_Glam -------------R--------TTPMSD-------------VLG----------------
GK036_Glam -------------K--------RYPFSK-------------IFR----------------
GSK3B_Hsap -------P-RTPPEAIALCSRLLEYTPTARLTPLEACAHSFF
GSK3A_Hsap -------S-RTPPEAIALCSSLLEYTPSSRLSPLEACAHSFF
Pk34A_Dmel -------T-AVPQDLCGLLNSCFIYEAAARISPMMACSHGSY
sgg_Dmel -------I-RTPTEAINLVSLLLEYTPSARITPLKACAHPFF
gskt_Dmel -------I-RTPAEAIDLVSKMLIYSPNARVSPLMGCAHPFF
GSK3B_Mmus -------P-RTPPEAIALCSRLLEYTPTARLTPLEACAHSFF
GSK3A_Mmus -------SSKTPPEAIALCSSLLEYTPSSRLSPLEACAHSFF
R03D7.5_Cele --------KMLDSEIYDFMKATLKIDPKKRKSAIDVLKMPLF
F21F3.2_Cele --------D-ISPDQLQFIKRILVYAPEKRLRGKQLLQDDFF
C44H4.6_Cele -------R-KLSLSTLELLNSLMKMDPKLRIKPYEALTLPYF
C36B1.10_Cele -------YS-DMKDSVELLRQVLVYNPSRRLCGIEFLTNPFF
RIM11_Scer -------K-E-DDQTVEFLADVLKYDPLERFNALQCLCSPYF
MRK1_Scer -------A-E-DPDTLDLLTKTLKYHPCERLVPLQCLLSSYF
MCK1_Scer --------H-SGPDGIDLLMKILVYEPQQRLSPRRILAHQFF
Y106G6D.4_Cele --------T-ENQEWADFLGAILRYRPRERLHGPKLLSHPFF
Y106G6E.1_Cele -------QD-DMKESVAVLLQILVYNPNKRLSGIEILTHPYF
Y18D10A.5_Cele -------V-HTPAEAIDLISKIIEYTPTSRPTPQAACQHAFF
YOL128C_Scer --------S-IEFFDVEFLLKVLTYDATERCDARQLMAHEFF
GlkA_Ddis -------NV-EDKTVVDLLSKIFIFDPVKRASIDEIIAHP-F
GSK-3_Ddis -------AKDVPAESIDLISKILLYDPSSRLKPVEICAHPFF
19912_Tthe -----------------------------------------E
19923_Tthe -------NCKVDPLAIDLISKVLVYSPQLRLKPLEALAHPFF
19924_Tthe -------NCRIDPLAIDLISKILVYNPEKRLKPLEALLHPFF
2636_Tthe -------YIKDIDNLMDLITKCLQYLPENRITADEALQHPFF
5825_Tthe ------AKQKPDPMLIDLISRLLVFVPTDRPTPLETLLHPYF
7876_Tthe --KVSEDEKQKFNQLMDLISRVLVYAPSERPSPLQALAHPFF
GSK3_Spur -------A-RTPADAIQLCSRLLEYTPKSRIKPLEACAHQFF
n1163_Tthe NANIF-AKQKPDPMLIDLISRLLVFVPTDRPTPLETLLHPYF
CC1G_03802_Ccin -------P-RTAPEAIDLVSKLLEYTPGARLSAVEAMVHPFF
AqueK117_Aque -------P-RTPPEAIDLVSRLLEYTPTMRITTLDSCAHSFF
GSK_b_Smoe -------K-RMPPEAVDLVSRLLQYSPSLRCNALEALVHPFF
GSK_a-2_Smoe -------K-RMPPEAVDLVSRLLQYSPNLRCSSLEALAHPFF
GSK_a-1_Smoe -------K-RMPPEAVDLVSRLLQYSPNLRCSSLEALAHPFF
GK035_Glam -------T-K-DPVVLDFFARCFKYSPNERITAYEALAHPFY
GK036_Glam -------S-KAHTDAVDLLTKVLVYDPKKRPTAMEILAHPFY