RTKE1_Mbre MMHSPR------------------GWLALVVIVLGCVCARAQLITQGCPMHLLEARETQ-
RTKE2_Mbre MYRVTF------------------WILAALTVAL-------AADAPGCPVHLLVAKNVYT
RTKE3_Mbre MGKGKA---------------VVTPLLAAVLFGL------WHHAASDCPIRLLGFRDHLI
RTKE5_Mbre MQRVLAE---------------CGSLLAS-------------------------------
RTKE4_Mbre MAGAAAPAPLFDRRRSLPLLLLLLLLLLLLLISL------FSGAVATCPVVP--------
* *
RTKE1_Mbre HFS-----CFNCTN--DLIALRYVPHYTVCTLKPAYEVDPICKRRVFWTRFVC----MSN
RTKE2_Mbre TPE-----CFDCSDLQDQNGIKLASINSTCILNPNEGSD--CLSKFWWTHYDC----HPK
RTKE3_Mbre -PVEFGPLKTDCGRY----WEDSVPVGTVCSFDKSY-------RYMFWTHFRC----IED
RTKE5_Mbre -----------------------GIASASLTPDVGSIVI--DGVD-AWNG-TSVTIDLPF
RTKE4_Mbre --PRFD--GQTCSGS----LETLAMCNVTCSPDVPLSLQ--CQGD-TWTG-SC----LPS
. *. .
RTKE1_Mbre NMFELDSS-GNI-----------------SDVYARAG-------CQVSFNAS--------
RTKE2_Mbre GYFLLNRVFGQL-----------------NEVYANAG-------CEVTFDAE--------
RTKE3_Mbre STFVLDEA-GNM-----------------TSRFEQAG-------CTIRGSF---------
RTKE5_Mbre PATLASIT-AQNGPDGEYEALSIELFSGASSVLSLTG-------------------ILLH
RTKE4_Mbre SALRNCRP-HQILPRGEYD------WYCSNAQAIPRGLAWDITSFAVSFPPETEMSPRLD
: . *
RTKE1_Mbre ----D--ASVSLICDGQTVAGEDKLSMMP---------------YGGAPSNLKNLIIR--
RTKE2_Mbre ----D--GRPSLICDGAN--TANRFKIMP---------------RGGAPSDLKQLVIR--
RTKE3_Mbre ----D--DEPELICRGVPG-QENMLDRLA---------------DGGAPSNLVGIEAT--
RTKE5_Mbre NGSNT--KTVVAPVDFQDQAAVDRIVVQP---------------QAGTVN----------
RTKE4_Mbre RLANLTQLTVLTLFELTDKVSPSKLPELPALSFIELVDCVRAAPLYPVAPRLKGWSVRGL
. : . .
RTKE1_Mbre HHRLADIA--LPATHAFQLLQKLDLSHNRIN---------------FIGSPALVWLFE--
RTKE2_Mbre NHNLHKCH--RDNVVMFQQLERLDLSNNKLE---------------YVHELAAQSLYS--
RTKE3_Mbre HHNISYVA--HHNVHGYAKLRYLNLAHNTLV---------------RLGNFVFEPLVR--
RTKE5_Mbre -ASLRLDVAVICIADRYPADYSLNASGPNTFAL--SNSPNVAASLEASGSLGVQTLQLIA
RTKE4_Mbre ESNLALNL--TILATRYPLLEYLRYSDNTIFDLVWAEVPPVFPHMRYLDSFWVQDMAS--
: . : * : . :
RTKE1_Mbre ---------LKYLDLSYND-L----------------TSLRPA-----QLPFS------R
RTKE2_Mbre ---------LKYLNLSHNL-L----------------SRLYAI-----HLPFE------N
RTKE3_Mbre ---------LTHLNMSNND-F----------------AALDGT-----MLPSY------G
RTKE5_Mbre SSAAAVQVTTPVLNHAFDFTRSRAYAVMLSTAAVSVGAQVDLEGTSPALTPASASLADTS
RTKE4_Mbre ---------LRGLSLSFPH-LEY-----FQITAVTGPAQIDHT-----VLPQA------G
*. : : : *
RTKE1_Mbre RLQYMD-------LRGNPLTTLRTDILISSMAANCTA-----IYLP--SACGSPSPGRCD
RTKE2_Mbre QLDTLD-------VRFNPIQEIRSDLLISAMSPNCSA-----IWLP--EACGLEALTDCT
RTKE3_Mbre LLQMLD-------LTNNPVTKMDISIFDACFPRDCRQRPAYILKLPQSETCQWTLQNRCY
RTKE5_Mbre AVQVLE-------FQFNAVVDT------------------A---------DFWLTL---D
RTKE4_Mbre SLRTMLIGITSFDTQVRALAY-------------------D---------AWWRILNITD
: : ..:
RTKE1_Mbre QLLTPS----------GSTTTLDPATTTAVDLV--TTAAPTTP--DAPVCQLEDAAV--A
RTKE2_Mbre ALLPVT----------APTP---------LPI---LTTNPSWNDNMATSCVVYEETL--N
RTKE3_Mbre GPIEVQ----------GAT---------------------------NSSCRILNANR--A
RTKE5_Mbre LTFSVASQVELVAVLLLDD----PL-------NCS-IEYGTFD--DAGTCRFCDG-----
RTKE4_Mbre LLLTPP----------DED----PITIASSDLTCIGMVNPTAV--LALHCNCYDPPYSGA
: * :
RTKE1_Mbre ----------MTC-PDASAQISSWQYCDG-----------------QQDCADGWDEHD--
RTKE2_Mbre ----------LTC-SDNSNTITNFQYCDG-----------------VQDCDNGWDEFE--
RTKE3_Mbre P---------APCLNDRSVTFETHQFCDG-----------------YRHCADGSDEFM--
RTKE5_Mbre -------TTDFSD-TLGANTCQTVTTCDGGNTYETMAPTISSDRVCAQFCASGATDHDDN
RTKE4_Mbre PFCPPPVMPRLSCLSAPNVHLDPTEICDG-----------------TAQCPDGEDEAG--
. *** * .* :
RTKE1_Mbre -------CSQ-RWLTARSSLLEPCSDGVLSM-----------------------------
RTKE2_Mbre -------CCQ-LWETSNIDFLGGCSDGELRL-----------------------------
RTKE3_Mbre -------CEP-PAIYTEAALIGACVNNYLKF-----------------------------
RTKE5_Mbre ATTPCETCAPGSYINPASPASGPCSDFICAAGTVDDDANVSTPCVACAAGHYVPANATGN
RTKE4_Mbre -------CRF-RIAFIDSQTITP-------------------------------------
*
RTKE1_Mbre -----------------------------------------TWHRGHA------------
RTKE2_Mbre -----------------------------------------RYQRGHA------------
RTKE3_Mbre -----------------------------------------FFLRGRA------------
RTKE5_Mbre CSLYICAAGEVDDDSDPSTPCIACAAGTYAPTGSVGPCTDFTCARGSKDLDGDPTTECEE
RTKE4_Mbre ------------------------------------------------------------
RTKE1_Mbre ----------------------------------------------------LARPPNAN
RTKE2_Mbre ----------------------------------------------------QLGPPDPT
RTKE3_Mbre ----------------------------------------------------IMRAANLD
RTKE5_Mbre CAAGTFDASATGSPEPLTECAACAVGTFSDAPGATSCNTCDSCGTGEYVARGCILTENVI
RTKE4_Mbre --------------EWPTF--ACLQ------------------GANMSVVRGVVRSDSQL
. .
RTKE1_Mbre -AMT-VCIPL---------LYTRWLAFAADTPE-----WNASASVHWVQELFDEPDGLF-
RTKE2_Mbre -FVAYDCYEF---------FRVRYTTATLDTMA----ITNDSTRIYWAPSLESSDGDLQ-
RTKE3_Mbre -AVAGTCVNS---------HYRQLQVSGFDPMV---NVSKDYVRLVWNIQIEEAVDVLAH
RTKE5_Mbre CASCSSCAEGDPVVTACTAYADTLCQSTLDAAT---NKSTNGDKMPLGIVLGVVAA----
RTKE4_Mbre -ALNQSCYEW---------HG-------CSSMILNRDASAPYVYISATARDHRQLNTDAN
* .. :
RTKE1_Mbre FVVSIDRSRIRIDGSVQGSVIVDTLNF-VPAPTN-----VP--------TTTSRP---AA
RTKE2_Mbre INTTLYRDELQL------TAEDDTTSFAFPAPIN-----SSNSINCDARTTIATT---AE
RTKE3_Mbre LTVDLERYVHVMLGEF------D----------------LGDDIIIYANQTQQTT-RVGN
RTKE5_Mbre IFVTLF-VVHFVHY----------------------RHRHGSETGVLPSVSR-QGSRGHV
RTKE4_Mbre ITGTYRVVEGNMLG---IAGSPAQTSDVLPARQTPEEFAAAYDALIYHPTTSSSTTPFGS
: : :
RTKE1_Mbre SSTTAPV-----------------------------------------------------
RTKE2_Mbre LTTIATT-----------------------------------------------------
RTKE3_Mbre TLTTAPL-----------------------------------------------------
RTKE5_Mbre YLASSDVPPAGPTRPGSANPNFMRPDPEVNRAPSSRRLSIVPLDEVRVRLQAGSKLGFSS
RTKE4_Mbre LSSVAP------------------------------------------------------
: :
RTKE1_Mbre IAEARASRS----ALPVIAAAIAAAV--VLVGIIIWVAVRTRRNR-DTQVPEDYETEALQ
RTKE2_Mbre -EASLVSRSSS--GMVVIASAMGAGLGLLVLGIIIFMCS--RRVKLDRPVWA-LEA-SAA
RTKE3_Mbre -PEGIPSRSHRDDILPIVGAVVGTMI--VIGAIVAVFAFRNR------------------
RTKE5_Mbre RRAGSVKRAASS-LLRLVCAQKCASVR---R--------------AYGFL----------
RTKE4_Mbre QATGSQSRASTI-LLVVIV-----------------------------------------
. .*: : ::
RTKE1_Mbre LFISSYPRAARDVPHLSAEWSALTARPGLWTANGTTRVLEHQP-FAQHYMLAATSPTMHV
RTKE2_Mbre VFARQYARVAQKSTELTSQLAAMTVSAREVTLKRQASIFATLP-FDQGFMTLSSTRKCYS
RTKE3_Mbre ------------------------------------------------------------
RTKE5_Mbre --------GVRVIAWLDPSCAATTRQEGGWRAERETMLIALGRLVVADFRVLGASMRMP-
RTKE4_Mbre -------------------------------------------IVVLVSLSLGA------
RTKE1_Mbre ALALPRTTATV-EEEHAVLSALVEARILLTMKDHPNVL----------------------
RTKE2_Mbre GVYLPAFPTT--EEQPNVERALVEARLLLCLQQHANVL----------------------
RTKE3_Mbre -------------------------RRLNCLHQHRHIL----------------------
RTKE5_Mbre SCSQPAFPRRVSPDHKGVLGVLLLLCLAMVMAQQPQLFIKNECPDSCSPDASVTLGYNGF
RTKE4_Mbre ------------------------------------------------------------
RTKE1_Mbre -------------------------------------HLVNVIHERQNIMLVYEPARLGV
RTKE2_Mbre -------------------------------------KVHHLASDDRVQILLYEEIQQGP
RTKE3_Mbre -------------------------------------NFAGYSTMKDGFILIYDMSNYTQ
RTKE5_Mbre TGSHIARPRADQWATWAINVSTDRLELCCIDFQSWTPALMGSYTNTD--YLVLDMLEQPS
RTKE4_Mbre ----------------AGFLWFNRRT----------------------------------
RTKE1_Mbre LSQAL-SSTSVSREQQQ---------------------AIC-GQVASACSYLESL--GIV
RTKE2_Mbre LDVAL-AQYKVTQAQGR---------------------EIC-LKVASACSFLESM--GIV
RTKE3_Mbre LADVL-RLDAPNPKESA---------------------LICQRQVAEACSFLDSL--GIV
RTKE5_Mbre ADLMSWIQTQRPKNLGIQWRDQRPATLDWAQLPWQKLRNLA-LGFFYKVSFGEDTFIPIG
RTKE4_Mbre ---EA-SQVKVSVQANI---------------------RFL-RQLAAGLSFLEDL--KLI
: . *: :. :
RTKE1_Mbre HRNLGAHSVYACQSIDDVRLAGFVMAKDVYLTQEYVATVSKGRAKL--------------
RTKE2_Mbre HRNLGAHSIYACSDITDVRLAGFGLSRDVYFTEEYMTKNAA-ASQL--------------
RTKE3_Mbre HRNLGAHSVFCVGDITEVRLANITTARDVYLSQEYVARTIVNEATMASA----TAMGSSD
RTKE5_Mbre QDGLLQHCGLL-ATQPDNALNLSAMARDVYETQSYIQTNKLNRDGADKMDTWADGVGSSL
RTKE4_Mbre HGRVCTESVLVMNNAPLVKLFGFATP--TVPDQEDLAIKPESHTIVP-------------
: : .. * . . :. :
RTKE1_Mbre -------TPDRYFWSPEVWRDSVFSFKSDVYAFGRFCWQVCHGGQIPYADMSPTNFVQQS
RTKE2_Mbre -------APDRRFWSPEVWQDGNFSFKSDVFAFGRFFWQVYNNGQMPYKEMPERQFVSAS
RTKE3_Mbre THDEFSKQLAKRFWSAEVWSDQIFSTKSDVYAYGQLCWQVYNKGQLPYPGMSLQSIALHV
RTKE5_Mbre GLLGATQAEKLRFLSPEALDDNHFSSSSDVFAFGVLLWEVLLAET-MFKGESRPRIAQRI
RTKE4_Mbre -VWDPATWGSTRYFAPELLLCPHPTNPGDVFSYGALMYEVMANGTPIFAGLDGQQVLMRQ
: :.* : .**:::* : ::* : .
RTKE1_Mbre VNGSLPDLPPTEN-EFLEDLIKSCTQLAVKARPTFATLAAALWEDDIDVLE-PALMQR--
RTKE2_Mbre VTNALPALPVVED-PLAQRLIEACLRTQPRSRPRFGYDTKLTLRCLTGLLI--SQLYRSP
RTKE3_Mbre QQGTPPSVRAIPS-EHARRLILQCLRIKPESRPNFACVAFEVERCSLDRLD--AVMART-
RTKE5_Mbre RTHNMPALPVKYS-TFAD-VYSHLVDRVPARRPSFDNLYFMLLNAETP----ESGYL--P
RTKE4_Mbre RQAQLPPLPQTHNLPAATALYTECIAADPKERPAFRSIYQQLLQCEWAFEHEEKLSF--P
* : . : ** * .
RTKE1_Mbre NVPEIAVSRLNQMDGLEKVYDV-DGQL-MESI--AYGPTD----AVL-RELSFRVKLDSE
RTKE2_Mbre HACALILICYAFHSALVAALQE-ENAYMAVDA--TMVPTQ----LV---RIAVDRKLDCI
RTKE3_Mbre ---------------------------------------R---------------HIFHE
RTKE5_Mbre QLAVATIRPTWSTTDLIAGTATIDDARLAGSPVTCFIPRKANSDAHWTTQFHLLLQLPHD
RTKE4_Mbre NLPVQVRRRRALASGFDAVQVVTNAAQLSHTSLVALVRRDQ-DSATWTNSCRLANQLRHP
::
RTKE1_Mbre GLPAVLGT---VTF-GQNTMLLAEYLAVPMA--SQLNAELDGEMAFR-WLRTVLGTLEYL
RTKE2_Mbre ALPMLRAVAE-SSN-GEELVL-VDSYVTPLT--AHLNASVPVETGQR-WLEEVMVGLEYL
RTKE3_Mbre HLQMPVAH---TRV-GNQASILAPFASTSLTDYLQLHANMDLDTALG-LCRNALEAVEYL
RTKE5_Mbre GLVQVLSVTECTLEGARRPCLVVP-PCAPYA--SADPPLPAAQ-VVKELALDVLIVLEYL
RTKE4_Mbre HQQFVISHTRLYGDEGWEEALVVQ--DFPIL--TQLAPTPAVFRLRQWLCAQLLSWLDYM
. . . : . . . : ::*:
RTKE1_Mbre SSRNIHFMTVQLEDCRLTSTNQAKICN---CPFRPSS-----------------DG----
RTKE2_Mbre ASRHLYFTDFTVDNCYLDEEERVRLRN---CPLQPSSA----------------ES----
RTKE3_Mbre ASRRVLLEDLRVGDFRVTRHGVLKLDYGRQWGLTGLGASAEDNASRRSDSVS-TGGGGGG
RTKE5_Mbre AARQCAPRDIRLEHCVVLE-GRIGLVG---LALANVGASLGLLENYLSFLRE-ARGGLVA
RTKE4_Mbre AHRGLAVSGLSLSCCRVGA-GLLKVSG---MHIKHVPELAQAFREALAQLQGVIREAGVA
: * . : : : :
RTKE1_Mbre ------GGEASVAKAAGGLILDMCQFVPTID-SPELRQLGEVMKRGRLKKCSDVMLAI--
RTKE2_Mbre ------TDEVAVVRAAGQFIIDFCAQLPALS-ESGLPQLAEVMKRGRVKRCSDVILAI--
RTKE3_Mbre GGGGGALDEVVTVKAAGRFLVDLCELVAALRDQSELRQLGEVMRRGRVKKCGDGLLAL--
RTKE5_Mbre LNGNATLDRVIACVEAFMTRVDRYILPEAT--------TGDGLTRPQL--QSEALSA---
RTKE4_Mbre FGHAFASDRLVQ----------------------------DVVRRCDVVMGSQQLVADFR
.. : : * : .: : *
RTKE1_Mbre -------HAADPHRQLEVDADRLTFVRQLGEGEFGVVSLMTLLTTEG-------------
RTKE2_Mbre -------LSTYRERQLDIPFAQLTFVRKLGEGEFGEVNLMSMANQYG-------------
RTKE3_Mbre -------LSLDRQRRLELPYEQLTFVRALGQGEFGQVSLMTLREGG--------------
RTKE5_Mbre -LARELRDICQPNSSWNVPLSALQFVRVLGSGQFGEVWLASMPAHAHSSPNYSSKETAAA
RTKE4_Mbre RLVVDVEELCNPQRNFYINYSRLKFVRNLGAGAFGEVMLMELEGIS-------------S
. : * *** ** * ** * * :
RTKE1_Mbre -----SRHVAVKTLHNMTFMEDFKSEVAMMIKLRHPNLVGLLHTTSFGAREPAMILEYMP
RTKE2_Mbre ----STLQVAVKTLRDASLREDFMSEVTMMLKLHHPNLVGLLHTSQTTDGHLAMILEFMP
RTKE3_Mbre ----STRQVAVKLLLEAQHHKEYVAEVTMLSKMHHPNLMGLVHTTVTAEGHPGMVLEYMP
RTKE5_Mbre TSKREVMLVAVKRLLNDECLHEFEQELAIMMKIRHANLVRMLFVVQ-EKQHRALVLEYLD
RTKE4_Mbre EDQRKQRLVAVKRLLDSEVKDEFVQEMTTMRKLKHANLVQLLHVVD-DDAHPGLVIEYLD
**** * : .:: *:: : *::*.**: ::.. . .:::*::
RTKE1_Mbre GGSLETWLQERGRGTGPEDL-LYIAHQVTNGMAELARLGIVHRDLAARNVLVGRCL-NVK
RTKE2_Mbre GGSLEGWLEDRGRSVSQTDL-IYIAHQVASGMAELARLGIVHRDLAARNVLIGRAL-NAK
RTKE3_Mbre QGSLEGWLQARGTRVSHEDL-LLIAHQVAMGMNELARLGIVHRDLAARNVLIGRCL-NVK
RTKE5_Mbre GGALDSWLQGQSKPPSEERT-RHILHSIACGMLELQRLGMVHRDLAARNVLCDAQMQVVK
RTKE4_Mbre GGSLADWLDDHHARPLDTDLSIHVLHSIANGMAELVRCGVVHRDLAARNCSF-SWV-DIQ
*:* **: : : *.:: ** ** * *:********* : :
RTKE1_Mbre VADYGLSRTMTIGIASSESYYRIKTSRPLPIRWMAPSSILDQKVSTQTDVWSFGCLCYEI
RTKE2_Mbre VADYGLSRTMAIGTESEECYYRIKTSRPMPVRWMAPSTIVDRKFTSESDVWSYGCLLCEM
RTKE3_Mbre VADFGLSRVMQLGRDDSDAYYRIKTRQPMPLRWMAPESILSRKCDVRSDVWSYGCLCVEM
RTKE5_Mbre VADYGLSRSTRVGKDDEQAYYKFKTRRPMPVRWMAPEVLKTQKFTVATDVFSFGVLVGEV
RTKE4_Mbre VSDYGLSRATAVSHEGASEYYRIQTSRPLPLRWLAPEMLKDKMANEATDVYAYGVLMHEL
*:*:**** :. . . **:::* :*:*:**:**. : : :**:::* * *:
RTKE1_Mbre WSCGQIPFGNLSDPEVVQRLILAQQG-------------------QLREDEPVLASPASC
RTKE2_Mbre WSAGEMPFNDLDDQQVVERLLAAYAG-------------------RVPENEPVLASPKSC
RTKE3_Mbre WSGGELPYARLKDAEVLERLVAALQG-------------------HLKDGAVVLASPSRC
RTKE5_Mbre LTQAELPLAHLNDESLMLRITDCVKS-------------------GGYGGRPLHAPPVKA
RTKE4_Mbre FE-DDLPLAHLDDAAFMGLLVELSRKSSGLIRQRRSSLGSSGDHVEMQARAPAFEPPAHC
::* *.* .: : .* .
RTKE1_Mbre PPMISALMQTCLTVNGELRPSFATLSRRTHPQ-EWQALLT--------------------
RTKE2_Mbre PPLIDALIQSCLTVNGELRPNFIVLRRRTLPQ-VRIF-----------------------
RTKE3_Mbre PAGISDLIQSCLCINPELRLGFALLVQRTRPE-VSCAWC---------------------
RTKE5_Mbre PAWVSQIMVDCTLFDAAARPDFADLVVRLSPF-TFMASPTNAGRARTNTGASSMSSRRMT
RTKE4_Mbre PPALASVMRWCIDLNPMHRPTFAQLQDKWVAVGVSQA-----------------------
*. : :: * .: * * * : .
RTKE1_Mbre ------------------------------------------------------------
RTKE2_Mbre ------------------------------------------------------------
RTKE3_Mbre ------------------------------------------------------------
RTKE5_Mbre GTISQSSGLGPGRHASVSSIASSLRSNSGGPVLGHSNEGHERHKLLSETHDSRPLPSDYY
RTKE4_Mbre ------------------------------------------------------------
RTKE1_Mbre -----------------------------------------------------------R
RTKE2_Mbre -----------------------------------------------------------G
RTKE3_Mbre ------------------------------------------------------------
RTKE5_Mbre RANPVTELTMQSLRPPQQSTHAASQSETSPYLQPRGQSPSGANAYMRPQPLNLRGAPVSG
RTKE4_Mbre ------------------------------------------------------------
RTKE1_Mbre TDTPKH-----------PLLASVSH-----------------------------------
RTKE2_Mbre MGKPALLIYYFALTLLWHLLNSIGR-----------------------------------
RTKE3_Mbre ------------------------------------------------------------
RTKE5_Mbre MAQPSPLMMQQLASRPSPYPQAAPRSGSPPTSPGPSPLSPSSQSPPPWSGQQYNQRGPAN
RTKE4_Mbre AATPTALPAS----------Q---------------------------------------
RTKE1_Mbre ---------------------------------------------LFSG------LELE-
RTKE2_Mbre ---------------------------------------------LWSAST-YPPPGFRD
RTKE3_Mbre ----------------------------------------------FSFIQ-FTPV---C
RTKE5_Mbre AYVQPRRLSGTGAEAVAGSTRLGSFSTSGPQHNQSATLSTGANAYLMPAFQHAPEMQLDT
RTKE4_Mbre ---------------------------------------------ATPRLILSPSPTLED
.
RTKE1_Mbre --DNETCL
RTKE2_Mbre M-SACTWT
RTKE3_Mbre L-HHCTWL
RTKE5_Mbre DAVDESHL
RTKE4_Mbre TNQSESRL
: