TLK2_Hsap MME---------------------------------------------------------
TLK1_Hsap MSVQ--------SSSGSLEGPPSWS-------QLSTS-----------------------
C07A9.3_Cele MSMLS--------MDGIVAGGGSSSGGGERSFVLEQK-----------------------
TLK1_Mmus MSVQ--------SSSGSLEGPPSWS-------RLSTS-----------------------
TLK2_Mmus MME---------------------------------------------------------
19858_Tthe MNKID--------NQN----------IAEKIQLLEQRISKNGQATIQSSFKQNIESLQDQ
4269_Tthe MQIDQ--------RK--------------KLELLDYRMRHPSTSPIK--------TI---
TLK_Spur MASGP-------------------------------------------------------
tlk_Dmel MSPGAHLQMSPQNTSSLSQHHPHQQ-------QQLQP-----------------------
AqueK208_Aque MEATDE----------LIEDTPFRS-------SQGSG-----------------------
TLK-1_Smoe MHDNVLLHLSSN--SNHSD-----------------------------------------
TLK-2_Smoe MHDNVLLHLSSN--SNHSD-----------------------------------------
*
TLK2_Hsap ------------------------------------------------ELHSLD------
TLK1_Hsap ---PTPGSAAAARSLLNHTPP---SGRPREGA--------M------DELHSLD------
C07A9.3_Cele -------------------------------------------------MFNTG------
TLK1_Mmus ---PTPGSAAAARSLLNHTPP---SGRPREGA--------M------DELHSLD------
TLK2_Mmus ------------------------------------------------ELHSLD------
19858_Tthe TTESFKGSANNGMTQQNSVENSQLE-KNNQASSNKENVKEE------EEIQSV-------
4269_Tthe ------NNFANIKQKLNGIDI---Y-KNNNEQ--------L------KDLHDNEEDDDDK
TLK_Spur ------------------------------------------------------------
tlk_Dmel ---PQQ----QQQHFPNHH-----------SA--------QQQSQQQQQQEQQN------
AqueK208_Aque ---T------GLNFTLNDN-----------SA--------S------FELETLD------
TLK-1_Smoe ----------------------------------------------------SL------
TLK-2_Smoe ----------------------------------------------------SL------
TLK2_Hsap --------P---------------------------------------RRQ-----ELLE
TLK1_Hsap --------P---------------------------------------RRQ-----ELLE
C07A9.3_Cele --------P---------------------------------------QNK-----ALPT
TLK1_Mmus --------P---------------------------------------RRQ-----ELLE
TLK2_Mmus --------P---------------------------------------RRQ-----ELLE
19858_Tthe ---------------------------------------------L-NKKG-----DYYE
4269_Tthe SEQDDYLNF------------------------------------D-DNQNNQGSLDFMN
TLK_Spur ------------------------------------------------------------
tlk_Dmel --------PQQQAQQQQQILPHQHLQHLHKHPHQLQLHQQQQQQLHQQQQQ-----HFHQ
AqueK208_Aque --------P---------------------------------------QKR-----ELLE
TLK-1_Smoe --------P---------------------------------------SKL-----AKLE
TLK-2_Smoe --------P---------------------------------------SKL-----AKLE
TLK2_Hsap ARFTGVGVS---------------------------------------------------
TLK1_Hsap ARFTGVASGS--------------------TGSTGSCSV---------------------
C07A9.3_Cele VQSSGSSSNHAPIVGESPLGTVSSTMATGDTGRVGNVTYMSSGMLGATQFMPQNSSHPST
TLK1_Mmus ARFTGVATGS--------------------TGSTGSCSV---------------------
TLK2_Mmus ARFTGVGVS---------------------------------------------------
19858_Tthe KQFY--------------------------------------------------------
4269_Tthe KNLSGFNNGG----------------------NFLYCTP---------------------
TLK_Spur ------------------------------------------------------------
tlk_Dmel QSLQGLHQGS--------------------------------------------------
AqueK208_Aque ARFMGRSLPM--------------------------------------------------
TLK-1_Smoe ARMAGKSIPA--------------------------------------------------
TLK-2_Smoe ARMAGKSIPA--------------------------------------------------
TLK2_Hsap ------------------------------------------------------------
TLK1_Hsap ------------------------------------------------------------
C07A9.3_Cele SVMMQQVPPQNGGATRSSPTEMQQCMQAMSEDSIEMRDYNSGVHHMHPHQMQMQQQQQHH
TLK1_Mmus ------------------------------------------------------------
TLK2_Mmus ------------------------------------------------------------
19858_Tthe ------------------------------------------------------------
4269_Tthe ------------------------------------------------------------
TLK_Spur ------------------------------------------------------------
tlk_Dmel ------------------------------------------------------------
AqueK208_Aque ------------------------------------------------------------
TLK-1_Smoe ------------------------------------------------------------
TLK-2_Smoe ------------------------------------------------------------
TLK2_Hsap ------------------------------------------------------------
TLK1_Hsap ------------------------------------------------------------
C07A9.3_Cele QQQYNMSYHNHQQQMQQMHYHQQQQQYQQQQAQHHQMYAPQIQQQQQQPQQQSQQQSAQQ
TLK1_Mmus ------------------------------------------------------------
TLK2_Mmus ------------------------------------------------------------
19858_Tthe ------------------------------------------------------------
4269_Tthe ------------------------------------------------------------
TLK_Spur ------------------------------------------------------------
tlk_Dmel ------------------------------------------------------------
AqueK208_Aque ------------------------------------------------------------
TLK-1_Smoe ------------------------------------------------------------
TLK-2_Smoe ------------------------------------------------------------
TLK2_Hsap ----K--GPLNSESSNQS--------------------LCSVGSLSD-------------
TLK1_Hsap --GAK--ASTNNESSNHS--------------------FGSLGSLSD-------------
C07A9.3_Cele PQQSSAALQHVNESSNLS----------------------SAGSISD-------------
TLK1_Mmus --GAK--ASTNNESSNHS--------------------FGSLGSLSD-------------
TLK2_Mmus ----K--GPLNSESSNQS--------------------LCSVGSLSD-------------
19858_Tthe ------------ESSNLQ--------------------IGQVMHKMD-------------
4269_Tthe --P--VKIN-NNYGNNPSILNNPHLIKSFNEENNDLDQQNSSENNSD-------------
TLK_Spur ------------------------------------------------------------
tlk_Dmel ---------S-NPDSNMS--------------------TGSSHSEKDVNDMLSGGAATPG
AqueK208_Aque --------TI-NTDSNIS--------------------AGSSEHDSE-------------
TLK-1_Smoe ----A--KPLP-DAS-----------------------PSSTDSDEDN------------
TLK-2_Smoe ----A--KPLP-DAS-----------------------PSSTDSDEDN------------
TLK2_Hsap ----------------------------------------------KEVE----TPEKKQ
TLK1_Hsap ----------------------------------------------KESE----TPEKKQ
C07A9.3_Cele ----------------------------------------------REPEQHGGTPQRPT
TLK1_Mmus ----------------------------------------------KESE----TPEKKQ
TLK2_Mmus ----------------------------------------------KEVE----TPEKKQ
19858_Tthe ----------------------------------------------EVAE----QLEQL-
4269_Tthe ----------------------------------------------EEER----EIEE--
TLK_Spur --------------------------------------------------------VYRT
tlk_Dmel AAAAAIQQQHPAFAPTLGMQQPPPPPPQHSNNGGEMGYLSAGTTTTTSVL----TVGKPR
AqueK208_Aque ----------------------------------------------PQTS----QPEKPK
TLK-1_Smoe ----------------------------------------AGDFMIQASA----SSQKRK
TLK-2_Smoe ----------------------------------------AGDFMIQASA----SSQKRK
TLK2_Hsap ------ND-QRNRKRKAE--PY-ETSQG--------------------------------
TLK1_Hsap ------SESSRGRKRKAE--NQNESSQG--------------------------------
C07A9.3_Cele APQSSTATDKKTRKRRK-AGPT-E-DQ---------------------------------
TLK1_Mmus ------SESSRGRKRKAE--SQNESSQG--------------------------------
TLK2_Mmus ------ND-QRNRKRKAE--PY-DTSQG--------------------------------
19858_Tthe ----EQDD-EENQENKSNKNNQ-HQSNGQGLLNSDNIWDKQNSNQEGNYQNDTDEFYAPQ
4269_Tthe ----DENV-SS-------------------------------------------------
TLK_Spur -------NDQRSRQE---------------------------------------------
tlk_Dmel ------TPAERKRKRKMP--PCATSADE--------------------------------
AqueK208_Aque ------P--PRARKRQLSEENGPSSKTG--------------------------------
TLK-1_Smoe ------T-FQMDESREVS--EWTVTRKS--------------------------------
TLK-2_Smoe ------T-FQMDESREEE--KLDQEGRT--------------------------------
TLK2_Hsap ------------------------------------------------------------
TLK1_Hsap ------------------------------------------------------------
C07A9.3_Cele ------------------------------------------------------------
TLK1_Mmus ------------------------------------------------------------
TLK2_Mmus ------------------------------------------------------------
19858_Tthe EKLSDFSSMNILEAKDMQQQQLLKIPQPQIQQQNMLQVQQQLEQSDRHQQQQNAILQQGI
4269_Tthe -------------------------------------NNEELEEDDSNQDQQESLEKDAS
TLK_Spur ------------------------------------------------------------
tlk_Dmel ------------------------------------------------------------
AqueK208_Aque ------------------------------------------------------------
TLK-1_Smoe ------------------------------------------------------------
TLK-2_Smoe ------------------------------------------------------------
TLK2_Hsap ------------------------------------------------------------
TLK1_Hsap ---------------------F----------------------------P---------
C07A9.3_Cele ------------------------------------------------------------
TLK1_Mmus ------------------------------------------------------------
TLK2_Mmus ------------------------------------------------------------
19858_Tthe TTNQSTG-GASSLGQK-GTQ-------------------------------NTNTP----
4269_Tthe -SQQSIKNEKQNKSQVSQIEKS----------------------------QKQQPPQKAE
TLK_Spur ------------------------------------------------------------
tlk_Dmel --------------------AGSGGGSGGAGATVVNNSSLKGKSLAFRDMP---------
AqueK208_Aque --------------------KS----------------------------P---------
TLK-1_Smoe ------------------------------------------------------------
TLK-2_Smoe ------------------------------------------------------------
TLK2_Hsap ------------------------------------------------------------
TLK1_Hsap ------------------------------------------------------------
C07A9.3_Cele ------------------------------------------------------------
TLK1_Mmus ------------------------------------------------------------
TLK2_Mmus ------------------------------------------------------------
19858_Tthe ---VMQ------NSREKYQKSTGKKRRTTQTTLAMNKLKKYDT--TTPCPSIVQIQNTNQ
4269_Tthe NFEPTIKKVRVLNSQKILFQENTFPNENEKPINQQSGQSGEQVKKTEDIKNIVNQI--GL
TLK_Spur ------------------------------------------------------------
tlk_Dmel ------------------------------------------------------------
AqueK208_Aque ------------------------------------------------------------
TLK-1_Smoe ------------------------------------------------------------
TLK-2_Smoe ------------------------------------------------------------
TLK2_Hsap ------------------------------------------------------------
TLK1_Hsap ---------------------NLPVFQSLAYWEMGRTA------------------G---
C07A9.3_Cele ------------------------------------------------------------
TLK1_Mmus ------------------------------------------------------------
TLK2_Mmus ------------------------------------------------------------
19858_Tthe VSNRPRLNSESSNSNEAIQLNN--------------------------------------
4269_Tthe IQVKNAAK-----------NNN--------------------------------------
TLK_Spur ------------------------------------------------------------
tlk_Dmel ---------------------KVNMSLN-LGDRLGGSAGSGVGAGGAGSGGGGAGSGSGS
AqueK208_Aque ------------------------------------------------------------
TLK-1_Smoe ------------------------------------------------------------
TLK-2_Smoe ------------------------------------------------------------
TLK2_Hsap ---KG-----T-PRGHKISDYFEFAGG---------SAPGTSPGRS--------------
TLK1_Hsap --GKS-----IGGRGHKISDYFEYQGG---------N--GSSPVRG--------------
C07A9.3_Cele ----A-----TPKQERKITEFMKVGGE---------VASGNSVARC--------------
TLK1_Mmus ---KS-----IGGRGHKISDYFEYQGG---------N--GSSPVRG--------------
TLK2_Mmus ---KG-----T-PRGHKISDYFEFAGG---------SGPGTSPGRS--------------
19858_Tthe ----V-----PPPGNSKITQFFKMKNT---------PTQNTTAISG--------------
4269_Tthe ----K-----TQKKISKITDYLNQDQV---------NK-N--------------------
TLK_Spur ------------------------------------------------------------
tlk_Dmel GGGKSARLMLPVSDNKKINDYFNKQQTGVGVGVPGGAGGNTAGLRGSHTGGGSKSPSSAQ
AqueK208_Aque ----------KMDPSKKISEYFPSKGT---------SGTNSS------------------
TLK-1_Smoe ---WI------TKAGQ-QR----AAEE---------------------------------
TLK-2_Smoe ---TK------SSRGMGQR----SRGG---------------------------------
TLK2_Hsap -------------------------------------VPPVARSSPQHSLSNPLPRRVEQ
TLK1_Hsap -------------------------------------IPPAIR-SPQNSHSHSTPSS---
C07A9.3_Cele -------------------------------------LLTEYH-QNQ-----GSPK--RQ
TLK1_Mmus -------------------------------------IPPAIR-SPQNSHSHSTPSS---
TLK2_Mmus -------------------------------------VPPVARSSPQHSLSNPLPRRAEQ
19858_Tthe -------------------------------------QPLN-NLNSQPQQQNQINNQAPQ
4269_Tthe ------------------------------------------------------------
TLK_Spur ------------------------------------------------------------
tlk_Dmel QQQTAAQQQGSGVATGGSAGGSAGNQVQVQTSSAYALYPPAS-PQTQTSQQ----QQQQQ
AqueK208_Aque ------------------------------------------------------------
TLK-1_Smoe ------------------------------------------------------------
TLK-2_Smoe ------------------------------------------------------------
TLK2_Hsap PLYGLDGSAAKEATEEQSALPTL-------MSVMLAKPRLDTEQLAQRGAGLCFTFVSAQ
TLK1_Hsap ---------------------------------------------------------SVR
C07A9.3_Cele PAVQQNGSNSYDSQQQQ---PQM-------NQHEM-Q---------NSYWGVATPSLGVN
TLK1_Mmus ---------------------------------------------------------SVR
TLK2_Mmus PLYGLDGSAAKEASEEQSALPTL-------MSVMLAKPRLDTEQLAPRGAGLCFTFVSAQ
19858_Tthe TPSQQNGQQ---VSQK-----EN-------INIQVLPPQ-----NL--SNGQSLQTPSIS
4269_Tthe ------------------------------------------------------------
TLK_Spur ------------------------------------------------------------
tlk_Dmel PGSDFHYVNSSKAQQQQQRQQQQ-------TSNQMVPPHV-----VVGLGGHPLSLASIQ
AqueK208_Aque ------------------------------------------------------------
TLK-1_Smoe --------WANEAGVEKQKRPSV-------LTHHLLQ-----------------R-----
TLK-2_Smoe --------KAKEAKR-PHSPPSAKVDFSFLFSLSVLY-----------------RFLK--
TLK2_Hsap -QNSPSST-----------------------------------------------GSGNT
TLK1_Hsap -PNSPSPT-----------------------------------------------ALAFG
C07A9.3_Cele NRGTPTPTQQQHYSSD---------------------------------------SNSNS
TLK1_Mmus -PNSPSPT-----------------------------------------------ALAFG
TLK2_Mmus -QNSPSST-----------------------------------------------GSGNT
19858_Tthe QYNTPMATQNNSNYPNTNKKSVQNTSNGMMIDENKIQQNGALAHLQSPSQSVSSIANANS
4269_Tthe -------ANNNN---------------------------------------MFSKSTGNS
TLK_Spur ------------------------------------------------------------
tlk_Dmel -QQTPLSQ-----------------------------------------------QQQQQ
AqueK208_Aque ----C-SQ----------------------------------------------------
TLK-1_Smoe ----------------------------------------------------------LT
TLK-2_Smoe ----------------------------------------------------------VD
TLK2_Hsap EHSCSS-Q----------------------------------------------------
TLK1_Hsap DHPIVQ-P----------------------------------------------------
C07A9.3_Cele NQSPPGQG----------------------------------------------------
TLK1_Mmus DHPVVQ-P----------------------------------------------------
TLK2_Mmus EHSCSS-Q----------------------------------------------------
19858_Tthe TNSNVQ------------------------------------------------------
4269_Tthe NNTET-------------------------------------------------------
TLK_Spur ------------------------------------------------------------
tlk_Dmel QQQ-QQQQQLGPPTTSTASVVPTHPHQLGSLGVVGMVGVGVGVGVGVNVGVGPPLPPPPP
AqueK208_Aque -------T----------------------------------------------------
TLK-1_Smoe TGMVRN-T----------------------------------------------------
TLK-2_Smoe NGNGAE-H----------------------------------------------------
TLK2_Hsap ----KQI----SIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLRANCDLRRQID
TLK1_Hsap ----KQL----SF--KIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQID
C07A9.3_Cele ----NQSGRMVRTIDEETQTDSSLSQAN----PQNAD------EVAKMNRIIEDHRRQIE
TLK1_Mmus ----KQL----SF--KITQTDLTMLKLAALESTKNQDLEKKEGRIDDLLRANCDLRRQID
TLK2_Mmus ----KQI----SIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLRANCDLRRQID
19858_Tthe -----QN----STSS--HHQHYNQLKLSSSNQMKIYD-PK-------LENRYQDLQEEIK
4269_Tthe -------------------------------------------------EQIQLLNRELK
TLK_Spur ------------------------------------------------------------
tlk_Dmel MAMPAAI--IT--YSKATQTEVSLHELQEREA----EHESGKVKLDEMTRLSDEQKSQIV
AqueK208_Aque ----RLV--FTSSNTAQTQTDINLERLKKLEKSTSQYEEDKE-----------LLQERVT
TLK-1_Smoe ----RDV----L-WSKFSTEDHW---IICWCAGLGEELDKARSEACQYQRTCQQLEKEIN
TLK-2_Smoe ----KRF----S-EDERLKEDLM--TLNARCAGLGEELDKARSEACQYQRTCQQLEKEIN
TLK2_Hsap EQ--QKMLEKYKERL-----------------------------------NRCVTMSKKL
TLK1_Hsap EQ--QKLLEKYKERL-----------------------------------NKCISMSKKL
C07A9.3_Cele ELNSKNSLERRKNEA-----------------------------------SK--ETIKRL
TLK1_Mmus DQ--QKLLEKYKERL-----------------------------------NKCISMSKKL
TLK2_Mmus EQ--QKMLEKYKERL-----------------------------------NRCVTMSKKL
19858_Tthe Q--KELELNEKNNII------------------------------------KYLEQD-KT
4269_Tthe E--KEQQLNQKQKQIENLENLVGKLKQSLQNAKSTNTSGQNSLNPTIFDHSKIKRIVQKM
TLK_Spur -------------------------------------------------------EVFKL
tlk_Dmel GN--QKTIDQHKCHI-----------------------------------AKCIDVVKKL
AqueK208_Aque QL--EAILSNSSDK---------------------------------------IELLTG-
TLK-1_Smoe DM-KEVQLEKERKRL---------------------------------------KVVSDL
TLK-2_Smoe DM-KEVQLEKERKRL---------------------------------------KVVSDL
TLK2_Hsap LIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQRE
TLK1_Hsap LIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQRE
C07A9.3_Cele LIDKNQIERKALRDKTAADSPRIGCFKTTRTGDSFRDQWVDGWAFAEMDKKTEQINAERN
TLK1_Mmus LIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQRE
TLK2_Mmus LIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQRE
19858_Tthe LLEVEKLKREEMRQYIAKEKQRLGEYVQTRDCTKFDETWQEGTEFKKIKERLRVIEAEKE
4269_Tthe FTENSFLNRKLIKMQLQQSKQRLGEYVVDL--QNFKEQWIDGFEVQELYSQLDQVQKKIK
TLK_Spur V--VAATENKQARTKSMEDRLRLGQFTTQRQGAKFVETWNDGYAFTDLVKRQEKIAKERE
tlk_Dmel LKEKSSIEKKEARQKCMQNRLRLGQFVTQRVGATFQENWTDGYAFQELSRRQEEITAERE
AqueK208_Aque KISKSTATKKEQREESVRNQLRLGRFSAQRQGAHFVDTWIDGFAFQELSQEQNDISVQKE
TLK-1_Smoe LIAVAKGERQEARLRVRQDSVRLGNVGVMRAGTLLSEVWEDGQALKDIQARLKSLLEQKD
TLK-2_Smoe LIAVAKGERQEARLRVRQDSVRLGNVGVMRAGTLLSEVWEDGQALKDIQARLKSLLEQKD
. : . *:* : : * :* . .: . : : .
TLK2_Hsap EIERQRKMLAKRKPPAMG--QA-PPA-T----NEQKQRK------SK-TNG-A-------
TLK1_Hsap DIERQRKLLAKRKPPTANNSQA-PST-N----SEPKQRK------NKAVNG-A-------
C07A9.3_Cele EIASASALLKKRKPLGIGKEPKRPQAVNSQNDSNGMQPS------TS-SNTNG-------
TLK1_Mmus DIERQRKLLGKRKPPTANNSQA-PAT-N----SEAKQRK------TKAVNG-A-------
TLK2_Mmus EIERQRKMLAKRKPPAMG--QA-PPA-T----NEQKQRK------SK-TNG-A-------
19858_Tthe ELEKKKKNVKG---SRKST--------N---ETDI-------------------------
4269_Tthe YYQNVLQNLKTMKPKKKTQ--------T---NGKQ--QK------QLTLLG-S-------
TLK_Spur ELDQQRKSLMKRKPPNSPH------------PSSKSR---------PKQNG-P-------
tlk_Dmel EIDRQKKQLMKKRPAESGRKRN-NNS-N---QNNQQQQQQQHQQQQQQQNSNSNDSTQLT
AqueK208_Aque EIEKQKKLLAAKKKIVSSS------------GSKRAG---------KSSPT-L-------
TLK-1_Smoe AIEKQRKLLKKKQNDKT--------------------------------DA-S-------
TLK-2_Smoe AIEKQRKLLKKKQNDKT--------------------------------DA-S-------
:
TLK2_Hsap ------------------------------------------------------------
TLK1_Hsap ------------------------------------------------------------
C07A9.3_Cele ------------------------------------------------------------
TLK1_Mmus ------------------------------------------------------------
TLK2_Mmus ------------------------------------------------------------
19858_Tthe ------------------------------------------------------------
4269_Tthe ------------------------------------------------------------
TLK_Spur ------------------------------------------------------------
tlk_Dmel SGVVTGPGSDRVSVSVDSGLGGNNAGAIGGGTVGGGVGGGGVGGGGVGGGGGRGLSRSNS
AqueK208_Aque ------------------------------------------------------------
TLK-1_Smoe ------------------------------------------------------------
TLK-2_Smoe ------------------------------------------------------------
TLK2_Hsap -------------------------------------------------ENETPSSGNTE
TLK1_Hsap -------------------------------------------------ENDPFVR----
C07A9.3_Cele -------------------------------------------------DDAIFRR----
TLK1_Mmus -------------------------------------------------ENDPFVR----
TLK2_Mmus -------------------------------------------------ENE--------
19858_Tthe ------------------------------------------------------------
4269_Tthe -------------------------------------------------LNDPSTQ----
TLK_Spur -------------------------------------------------NDEGFAK----
tlk_Dmel TQANQAQLLHNGGGGSGGNVGNSGGVGDRLSDRGGGGGGIGGNDSGSCSDSGTFLK----
AqueK208_Aque -------------------------------------------------DSDGFTK----
TLK-1_Smoe -------------------------------------------------ES---------
TLK-2_Smoe -------------------------------------------------EN---------
TLK2_Hsap LKDTAPALGAH-SLL----------------RLT--L-AEYHEQEEIFKLRLGHLKKEEA
TLK1_Hsap ---------PN-LPQ----------------LLT--L-AEYHEQEEIFKLRLGHLKKEEA
C07A9.3_Cele ---------PE-EPK----------------EIQ--Y-QEYIELDEIYKLRREHLRKEET
TLK1_Mmus ---------PN-LPQ----------------LLT--L-AEYHEQEEIFKLRLGHLKKEEA
TLK2_Mmus -------------------------------TLT--L-AEYHEQEEIFKLRLGHLKKEEA
19858_Tthe -------------SQ---------------------E-LDLAEQKQRINLQIQFLQKEEA
4269_Tthe ---------AN-SNQDSNSKLTFEDEDEFDTSIYPNQAVAHEEQKRFTAFQITLLQKQEE
TLK_Spur ---------PL--PE----------------YMN--H-AEFYERDEITKLRQAAFKKEES
tlk_Dmel ---------PDPVSG----------------AYT--A-QEYYEYDEILKLRQNALKKEDA
AqueK208_Aque ---------PQ--AP----------------GIS--M-SEFLEKDEILKLRGAALKKEDL
TLK-1_Smoe -------------DQ----------------GLA--E-EECIATEEMYRARIFSIKREEE
TLK-2_Smoe -------------DQ----------------GLA--E-EECIATEEMYRARIFSIKREEE
.. : :::::
TLK2_Hsap EIQAELERLERVRNLHIRELKRIHNEDNSQF-KDHPTLNDRYLLLHLLGRGGFSEVYKAF
TLK1_Hsap EIQAELERLERVRNLHIRELKRINNEDNSQF-KDHPTLNERYLLLHLLGRGGFSEVYKAF
C07A9.3_Cele DLSMEKERLEKEKQHHVRELKRASNESASQF-NDHRLLHKRYLMLNLLGKGGFSEVWKAF
TLK1_Mmus EIQAELERLERVRNLHIRELKRINNEDNSQF-KDHPTLNERYLLLHLLGRGGFSEVYKAF
TLK2_Mmus EIQAELERLERVRNLHIRELKRIHNEDNSQF-KDHPTLNDRYLLLHLLGRGGFSEVYKAF
19858_Tthe DLIEMYKNLDHEKFLFVQKLKRFQDEQNSRYGQEWPCLGERYQLLSLLGRGGFSEVYKAY
4269_Tthe VIVNNLNQKKK----EVKEIIKNSRYGGIQVENPWPILGERYQLLSLLGKGGFSEVYKAI
TLK_Spur DLQGELEKLERERNLHIRELKRIHNEDQSTF-KNHKVLNDRYLLLRLLGKGGFSEVYKGY
tlk_Dmel DLQLEMEKLERERNLHIRELKRILNEDQSRF-NNHPVLNDRYLLLMLLGKGGFSEVHKAF
AqueK208_Aque NILQLREKLERERNLHIRELKRIAAEDNSRF-NDHPVLHNRYLLLHLIGKGGFSEVHK--
TLK-1_Smoe NTLRDRERYELEKACFIRELKRIRDEDGSRF-NHFPILNKRYALLNLLGKGGFSEVYKAY
TLK-2_Smoe NTLRDRERYELEKACFIRELKRIRDEDGSRF-NHFPILNKRYALLNLLGKGGFSEVYKAY
:. . :::: : : * .** :* *:*:****** *
TLK2_Hsap DLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSF
TLK1_Hsap DLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTF
C07A9.3_Cele DIEENRYVACKIHHVNKDWKEEKKANYVKHAMREKDIHKSLDHCRIVKQYDLLTIDNHSF
TLK1_Mmus DLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTF
TLK2_Mmus DLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSF
19858_Tthe DLHEFKEVACKIHQLNLNWSEPSKANYIKHAVRESKIHSELKHANIVQLYDTVEIDNNSF
4269_Tthe DLEEFREVAIKIHYIDKSWSNRVKQNYLKHAFREHGIQKELNHPNIVKLYDYIEIDSTSF
TLK_Spur DLKDHRDVACKIHQLSKEWKEDKKANYIKHALREYEIHKSLDHARVVKLYDVFEIDANSF
tlk_Dmel DLKEQRYVACKVHQLNKDWKEDKKANYIKHALREYNIHKALDHPRVVKLYDVFEIDANSF
AqueK208_Aque --------------------------------------------HIVQLYDVFEIDADSF
TLK-1_Smoe DMVEYRYVACKLHGLNVQWSEEKKQNYIRHAIREYNIHKSLVHSHIVRLWDIFEIDHNTF
TLK-2_Smoe DMVEYRYVACKLHGLNVQWSEEKKQNYIRHAIREYNIHKSLVHSHIVRLWDIFEIDHNTF
.:*: :* . :* :*
TLK2_Hsap CTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILL
TLK1_Hsap CTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILL
C07A9.3_Cele CTVLEYVPGNDLDFYLKQNRSISEKEARSIIMQVVSALVYLNEKSTPIIHYDLKPANILL
TLK1_Mmus CTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILL
TLK2_Mmus CTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILL
19858_Tthe ATILEYCEGPDLYFYLKKHKVLPEKEAKILIRQILCALRYMNSLKTRIIHYDLKPQNIIF
4269_Tthe ASVLQFCEGPDLSQHLKIHSTIIEQDAKYIVKKILECLEYLSSFQSKVIHYDLKPQNIIF
TLK_Spur CTVLEFCPGNDLDFHLKQHKLMVEREARCIIMQVVSALKYLNERKPPIIHYDLKPGNILL
tlk_Dmel CTVLEYCDGHDLDFYLKQHKTIPEREARSIIMQVVSALKYLNEIKPPVIHYDLKPGNILL
AqueK208_Aque CTVLEFVSGNDLDFLLKQNKTLPEKEARSVVVQTLTALKYLNEIRPPIIHFDLKPGNILL
TLK-1_Smoe CTVLQYCGGKDLDAVLKSTSVLPEREARSIMVQIFSGLVYLNRRSQRVIHYDLKPGNVLF
TLK-2_Smoe CTVLQYCGGKDLDAVLKSTSVLPEREARSIMVQIFSGLVYLNRRSQRVIHYDLKPGNVLF
.::*:: * ** ** : *::*: :: : . * *:. :**:**** *:::
TLK2_Hsap VNGTACGEIKITDFGLSKIMDDDSYNSV-DGMELTSQGAGTYWYLPPECFVV-----GKE
TLK1_Hsap VDGTACGEIKITDFGLSKIMDDDSYG-V-DGMDLTSQGAGTYWYLPPECFVV-----GKE
C07A9.3_Cele ESGNTSGAIKITDFGLSKIMEGESDDH-DLGIELTSQFAGTYWYLPPETFIV-------P
TLK1_Mmus VDGTACGEIKITDFGLSKIMDDDSYG-V-DGMDLTSQGAGTYWYLPPECFVV-----GKE
TLK2_Mmus VNGTACGEIKITDFGLSKIMDDDSYNSV-DGMELTSQGAGTYWYLPPECFVV-----GKE
19858_Tthe HK----GELKISDFGLSKIFDDGQ-----TRMELTSQGVGTYWYLPPETFEF------EN
4269_Tthe HK----GQIKITDFGLSKIIEDNA-----TRLELTSQGVGTYWYLPPECFENFGCEENEK
TLK_Spur CHGSTCGAIKLTDFGLSKVMDDEHFNSQEGGMDLTSQGAGTYWYLPPECFVV-----GKE
tlk_Dmel TEGNVCGEIKITDFGLSKVMDDENYNP-DHGMDLTSQGAGTYWYLPPECFVV-----GKN
AqueK208_Aque GSGIYSYEAKITDFGLSKIVEQEG---TDGMVELTSQGAGTYWYLPPECFVI-----GKE
TLK-1_Smoe DE---AGAAKLTDFGLSKIVEDEV-G-S-QGMELTSQGAGTYWYLPPECFDV-----NK-
TLK-2_Smoe DE---AGAAKLTDFGLSKIVEDEV-G-S-QGMELTSQGAGTYWYLPPECFDV-----NK-
*::******:.: ::**** .********* *
TLK2_Hsap PPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEA
TLK1_Hsap PPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEA
C07A9.3_Cele PPKITCKVDVWSIGVIFYQCIYGKKPFGNDLTQQKILEYNTIINAREVSFPSKPQVSSAA
TLK1_Mmus PPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEA
TLK2_Mmus PPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEA
19858_Tthe SALISPKVDIWSVGVIFFEMVFGQRPFGNNKSQDQILKENIILKSTSVTFPSKPSVSNEC
4269_Tthe APTISNKVDIWSVGVIFYEMLFGQKPFGNKMTQEQILRQNTILNSKEVKFPKKPLISKEA
TLK_Spur PPKISSKVDVWSTGIIFYQCLYGKKPFGHNLSQASILEQNTILRATQVQFSPKPTVSQEA
tlk_Dmel PPKISSKVDVWSVGVIFYQCLYGKKPFGHNQSQATILEENTILKATEVQFSNKPTVSNEA
AqueK208_Aque PPKISSKVDVWSVGIIFFQCLYGKKPFGHNQSQASILEENVMLKATEVEFPSKPPVSNEA
TLK-1_Smoe TPLISSKVDVWSAGVLFYQMLFGKRPFGHDQSQERILREDTITKARKVEFPTRPSVSADA
TLK-2_Smoe TPLISSKVDVWSAGVLFYQMLFGKRPFGHDQSQERILREDTITKARKVEFPTRPSVSADA
.. *: ***:** *::*:: ::*::***:. :* **. : : .: .* *. :* :: .
TLK2_Hsap KAFIRRCLAYRKEDRIDVQQLACDPYLLPHIRKSVS-TSSPAGAAI-AST-S---GASNN
TLK1_Hsap KAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNS-SGNLHMAGLTASP-T---PPSSS
C07A9.3_Cele QDFIRRCLQYRKEDRADVFELAKHELFRPRGAIRASVAGSLLLVIITLCQHSNRSEDRLC
TLK1_Mmus KAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNS-SGNLHMSGLTATP-T---PPSSS
TLK2_Mmus KAFIRRCLAYRKEDRIDVQQLACDPYLLPHIRKSVS-TSSPAGAAI-AST-S---GASNN
19858_Tthe KDFIRNCLTYDQNRRWDIQKAWDSPYMNS-------------------------------
4269_Tthe QSFIIGCLKHNQEERFDVKQALNHPYFK--------------------------------
TLK_Spur KDFIRRCLMYRKEDRADVLALAKDPYLMPSNKKSSA-AAAAHASAAVSSP-QSHSNISNS
tlk_Dmel ------------------------------------------------------------
AqueK208_Aque KNFIKRCLTYRKEDRPDVITIIEDLYLQPKKAPAVP----------------GHS--GSP
TLK-1_Smoe KDFIRRCLSYDQMDRPDVLTAAQDPYLSYVKR----------------------------
TLK-2_Smoe KDFIRRCLSYDQMDRPDVLTAAQDPYLSYVKR----------------------------
TLK2_Hsap SSSN
TLK1_Hsap IITY
C07A9.3_Cele VSNV
TLK1_Mmus IITY
TLK2_Mmus SSSN
19858_Tthe -KTR
4269_Tthe --KA
TLK_Spur ENST
tlk_Dmel ---K
AqueK208_Aque GPTS
TLK-1_Smoe --KP
TLK-2_Smoe --KP