nsy-1_Cele      ---SNERVVLGKGTYGTVYAARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHAN
Pk92B_Dmel      ---QNRKMVLGKGTYGTVYAARDKQTQVRIAIKEVPEKNSQDVQPLHEEIKLHSQLRHRN
MAP3K5_Mmus     YDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKN
MAP3K6_Mmus     YSETGERLVLGRGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHKRLRHKN
MAP3K7_Mmus     HDANGERVVLGKGSYGIVYAGRDLSNQVRIAIKEIPERDIRYSQPLHEEIALHKYLKHRN
MAP3K7_Hsap     HDANGERVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYLKHRN
MAP3K5_Hsap     YDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKN
MAP3K6_Hsap     YTETGERLVLGKGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKN
ASK_Spur        ------------------------------------------------------------
AqueK224_Aque   ---LHEPVVLGKGSFGIVYSAIDLVTKKKMAIKEIPERTEGQFQSLEEEIQLHRHLQHEN


nsy-1_Cele      IVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMN--ENAMNYYGKQILEGL
Pk92B_Dmel      IVRYLGSC-----SENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGL
MAP3K5_Mmus     IVQYLGSF-----SENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGL
MAP3K6_Mmus     IVRYLGSA-----SQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGL
MAP3K7_Mmus     IVQYLGSV-----SENGYIKIFMEQVPGGSLSALLRSKWGPMK--EPTIKFYTKQILEGL
MAP3K7_Hsap     IVQYLGSV-----SENGYIKIFMEQVPGGSLSALLRSKWGPMK--EPTIKFYTKQILEGL
MAP3K5_Hsap     IVQYLGSF-----SENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGL
MAP3K6_Hsap     IVRYLGSA-----SQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGL
ASK_Spur        ----------------------MEQVPGGSLSALLRSKWGPLKDHEDTIIYYTKQILEGL
AqueK224_Aque   IVQYFGAY-----SDGGIFRIFMEQVPGGSLSHLLKFTWGPLINDEGTIRHYTRQILKGL
                                      **.******* **.  ***:   * :: .* :***:**

nsy-1_Cele      KYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGTLQYMAPEVI
Pk92B_Dmel      KYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTETFTGTLQYMAPEVI
MAP3K5_Mmus     KYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEII
MAP3K6_Mmus     SYLHENRIVHRDIKGDNVLINTFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEII
MAP3K7_Mmus     KYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFTGTLQYMAPEII
MAP3K7_Hsap     KYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEII
MAP3K5_Hsap     KYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEII
MAP3K6_Hsap     GYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEII
ASK_Spur        RYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGLNPAASSFKGTLQYMAPEVI
AqueK224_Aque   GYLHNQKIVHRDIKGDNVLVNMYSGQIKISDFG-----------------TFQFMAPEVI
                 ***:  ************:* :**  ******                 *:*:****:*

nsy-1_Cele      DHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKC
Pk92B_Dmel      DQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGSAHAAMFKVGFYKKHPNIPEELSANA
MAP3K5_Mmus     DKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEA
MAP3K6_Mmus     DQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPVPGSLSAEA
MAP3K7_Mmus     DQGPRGYGAPADIWSLGCTIIEMATSRPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEA
MAP3K7_Hsap     DQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEA
MAP3K5_Hsap     DKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEA
MAP3K6_Hsap     DQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSLSAEA
ASK_Spur        DKGLRGHGAPADIWSLGCTIVEMATGKPPFIELGSPQAAMFKVGFYKDHPEIPESLSNAA
AqueK224_Aque   ASGQRGYGPPADVWSLGCTVIEMVTGKPPFFELGPPEAAVFKVGTFKEHPEIPDVLSKEL
                  * **:* .**:**:*** :**.*.:*** *:  ..**:*:** :* ** :*  ::

nsy-1_Cele      RNFIKSCFLPEACDRPSAKDLLQDPFI
Pk92B_Dmel      KNFILRCFAISVMDRPSASQLLEDPFL
MAP3K5_Mmus     KAFILKCFEPDPDKRACANDLLIDEFL
MAP3K6_Mmus     QAFLLRTFEPDPRLRASAQELLGDPFL
MAP3K7_Mmus     RAFILSCFEPDPQKRVTAADLLQEGFL
MAP3K7_Hsap     RAFILSCFEPDPHKRATTAELLREGFL
MAP3K5_Hsap     KAFILKCFEPDPDKRACANDLLVDEFL
MAP3K6_Hsap     QAFLLRTFEPDPRLRASAQTLLGDPFL
ASK_Spur        KEFILRCFEPDPEKRATAHDLLQDPFL
AqueK224_Aque   KSFLLSCFEPEPSKRAIVSELLQNSFI
                : *:   *  .   *  .  ** : *: