Protein (view, download) , Domain (view, download)
CDK11a_Hsap     MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
CDK11b_Hsap     MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
CDK11_Mmus      MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  MHLVRG------MD----LD-RDRPDNERNGVRAYIATDSRDIE----------------
CDK11_a-2_Smoe  MSWVMD--------E------------------RSTSSRHRKSHRYSH------------
CDK11_b-1_Smoe  MHLVRG------MD----LD-RDRPDNERNGVRAYIATDSRDVE----------------
CDK11_a-1_Smoe  MSWVMD--------E------------------RSTSSRHRKSHRYSH------------
CDK11_c_Smoe    MQRR--------------------------------------------------------


CDK11a_Hsap     TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGK
CDK11b_Hsap     TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK
CDK11_Mmus      TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGK
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  ------------------------------------------------------GDDGIS
CDK11_a-2_Smoe  ----------------------------------------GDGRHHPYSHHHSSSSGGGS
CDK11_b-1_Smoe  ------------------------------------------------------GDDGIS
CDK11_a-1_Smoe  ----------------------------------------GDGRHHPYSHHHSSSSGGGS
CDK11_c_Smoe    ------------------------------------------------------------


CDK11a_Hsap     HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
CDK11b_Hsap     HARVK--EREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
CDK11_Mmus      HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  -------------RKRKY------------------------------------------
CDK11_a-2_Smoe  -------------RRRHR------------------------------------------
CDK11_b-1_Smoe  -------------RKRKY------------------------------------------
CDK11_a-1_Smoe  -------------RRRHR------------------------------------------
CDK11_c_Smoe    ------------------------------------------------------------


CDK11a_Hsap     MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR
CDK11b_Hsap     MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR
CDK11_Mmus      LREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREEYSDKGKVGHWSRSPLRPPR
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  ---------------------------------------------------SPI------
CDK11_a-2_Smoe  ---------------------------------------------------SPSPSKPLA
CDK11_b-1_Smoe  ---------------------------------------------------SPI------
CDK11_a-1_Smoe  ---------------------------------------------------SPSPSKPLA
CDK11_c_Smoe    ------------------------------------------------------------


CDK11a_Hsap     ER-FELGDGRKPGEARPAPAQ-KPAQLKEEKMEERDLLSDLQDISDSERKTSSAESSSAE
CDK11b_Hsap     ER-FELGDGRKPGEARPAPAQ-KPAQLKEEKMEERDLLSDLQDISDSERKTSSAESSSAE
CDK11_Mmus      ER-FEMGDNRKP--------------VKEEKVEERDLLSDLQDISDSERKTSSAESSSAE
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  --VWDLDDGKKSDAAPPLSRFSEAAAAGEDET----------QPIDTD--VLSSGGGGAQ
CDK11_a-2_Smoe  TSLLQLEEQLTTAQ-----AQ-APAT-------------------TSQERAASVSCSDGE
CDK11_b-1_Smoe  --VWDLDDGRKSDAAPPLSRFSEAAAAGEDET----------QPIDTD--VLSSGGGCAQ
CDK11_a-1_Smoe  TSLLQLEEQLTSAQ-----AQ-APAT-------------------TSQERAASVSCSDGE
CDK11_c_Smoe    ----------------P-CLYSEAAAAGEDET----------QPIDTD--VLSSGGG---


CDK11a_Hsap     SGSGSEEEEEEEE-EEEEEGSTSEESEEEEEE-EEEEEEETGSNSEEASEQSAEEVSEE-
CDK11b_Hsap     SGSGSEEEEEEEE-EEEEEGSTSEESEEEEEE-EEEEEEETGSNSEEASEQSAEEVSEE-
CDK11_Mmus      SGSGSEEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEEETGSNSEEASEQSAEEVSDE-
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  DNSGSRDEEQRYEQ-EL-------------------------------NEKELVELSDD-
CDK11_a-2_Smoe  VAAVVTLEVADLEEE-----------------VVNEEAE--------MSEVKVVDVAETS
CDK11_b-1_Smoe  DNSGSRDEEQRYEQ-EL-------------------------------NEKELVELSDD-
CDK11_a-1_Smoe  VAAAVTLEVADLEEE-----------------VVNEEAE--------MSEVKVVDVAETS
CDK11_c_Smoe    ----DKT------------------------------------------------IPGA-


CDK11a_Hsap     --EMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPAL
CDK11b_Hsap     --EMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPAL
CDK11_Mmus      --EMSEDEDRENENHILVVPESRFDRDSGDSEEGEEEVGEGTPQSSAPTEGDYVPDSPAL
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  --DGSAPDERS-------------G-SDSDYE-------------------DRSP-PPQL
CDK11_a-2_Smoe  EAGLAKLD------------------DDGDLE-------------------QGVPHTPEV
CDK11_b-1_Smoe  --DGSAPDERS-------------G-SDSDYD-------------------DRSP-PPQL
CDK11_a-1_Smoe  EAGLAKPD------------------DDGDLE-------------------QGVPHTPEV
CDK11_c_Smoe    --EMRSSDERL-------------G-SDLDYD-------------------DRSP-PPQL


CDK11a_Hsap     SPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKME-
CDK11b_Hsap     LPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKME-
CDK11_Mmus      SPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKME-
CDK11_d_Smoe    --------------MLRGCRSVDEFERLNKIDEGTCGVVYRARDKKSGEIVALKRVKMD-
CDK11_b-2_Smoe  RSI----------DMLRGCRSVDEFERLNKIDEGTYGVVYRARDKKSGEIVALKRVKMD-
CDK11_a-2_Smoe  QDVKC-------SSPCGKCRIVDEFEKLGRLGEGAYGVVYKARDKRTEEIVALKKIKMHN
CDK11_b-1_Smoe  RSI----------DMLRGCRSVDEFERLNKIDEGTYGVVYRARDKKSGEIVALKRVKMD-
CDK11_a-1_Smoe  QDVKC-------SSPCGKCRIVDEFEKLGRLGEGAYGVVYKARDKRTEEIVALKKIKMHN
CDK11_c_Smoe    RSI----------DMLRGCRSVDEFERLNKIDEGTYGVLYRARDKKSGEIVALKRVKMV-
                                  ** *:**: *.:: **: **:*:*:**:: ******::**

CDK11a_Hsap     KEKEGFPITSLREINT-----------------------ILKAQHPNIVTVREIVV----
CDK11b_Hsap     KEKEGFPITSLREINT-----------------------ILKAQHPNIVTVREIVV----
CDK11_Mmus      KEKEGFPITSLREINT-----------------------ILKAQHPNIVTVREIVV----
CDK11_d_Smoe    HEREGFPMTSVREINV-----------------------LLSFHHPSIVDVKEVSL----
CDK11_b-2_Smoe  HEREGFPMTSLREINV-----------------------LLSFHHPSIVDVKEVVV----
CDK11_a-2_Smoe  QETEGFPVTSLREINL-----------------------LISLRHPAIVDVREVVI----
CDK11_b-1_Smoe  HEREGFPMTSLREINV-----------------------LLSFHHPSIVDVKEVVV----
CDK11_a-1_Smoe  QETEGFPVTSLREINL-----------------------LISLRHPAIVDVREVVI----
CDK11_c_Smoe    HERDGFPMTSRKSTFFSRFTIHRSWMSRKWWSHALQRNDQCSFNASSICTTTDQALLWNL
                :* :***:** :.                            . . . *  . :  :

CDK11a_Hsap     ---------------------------GSNMDK----IYIVMNYVEHDLKSLMETMKQPF
CDK11b_Hsap     ---------------------------GSNMDK----IYIVMNYVEHDLKSLMETMKQPF
CDK11_Mmus      ---------------------------GSNMDK----IYIVMNYVEHDLKSLMETMKQPF
CDK11_d_Smoe    ---------------------------MPYKAM----TSALS------------------
CDK11_b-2_Smoe  ---------------------------GSNLDS----IFMVMEYMEHDLKGLMDAMKQPF
CDK11_a-2_Smoe  ---------------------------GKDMDS----VFMVMEYIERNLKDVMAALPQPW
CDK11_b-1_Smoe  ---------------------------GSNLDS----IFMVMEYMEHDLKGLMDAMKQPF
CDK11_a-1_Smoe  ---------------------------GKDMDS----VFMVMEYIERNLKDVMAALPQPW
CDK11_c_Smoe    MTKKELGSLLPQALAEPMCRSGSDASAGRERDRGGVTRWRLLRLQRVDLEAKAGTGKKPT
                                                        :

CDK11a_Hsap     LPGEVK--TLMIQL---LRGVKHLHDNW----ILHRDLKTSNLLLSHAGILKVGDFGLAR
CDK11b_Hsap     LPGEVK--TLMIQL---LRGVKHLHDNW----ILHRDLKTSNLLLSHAGILKVGDFGLAR
CDK11_Mmus      LPGEVK--TLMIQL---LSGVKHLHDNW----ILHRDLKTSNLLLSHAGILKVGDFGLAR
CDK11_d_Smoe    ---------------------EYLH-----------------------------------
CDK11_b-2_Smoe  TQSEAK--CLMLQL---FEGVKYLHDNW----VLHRDLKTSNLLLNNRGDLKICDFGLAR
CDK11_a-2_Smoe  EHAVVK--HMMQQL---LDAVAYLHANW----VLHRDLKPSNILVS-GGELKICDFGMAR
CDK11_b-1_Smoe  TQSEAK--CLMLQL---FEGVKYLHDNW----VLHRDLKTSNLLLNNRGDLKICDFGLAR
CDK11_a-1_Smoe  EHAVVK--HMMQQL---LDAVAYLHANW----VLHRDLKPSNILVS-GGELKICDFGMAR
CDK11_c_Smoe    PKQDKSNRAAQIQAPGDSRGAKGNRDPRDLRGRLCRILKRGRRIII-VGHLNISPYPIDS
                                        :

CDK11a_Hsap     EYGSPLKAYTPVVVTLWYRAPELLL--------------------------GAKE----Y
CDK11b_Hsap     EYGSPLKAYTPVVVTQWYRAPELLL--------------------------GAKE----Y
CDK11_Mmus      EYGSPLKAYTPVVVTLWYRAPELLL--------------------------GAKE----Y
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  QYGSPLKTYTRMVVTLWYRAPELLL--------------------------GSKK----Y
CDK11_a-2_Smoe  RYDSPIKAYTHKVVTMWYRAPELLA--------------------------STQEEQYHY
CDK11_b-1_Smoe  QYGSPLKTYTRMVVTLWYRAPELLL--------------------------GSKK----Y
CDK11_a-1_Smoe  RYDSPIKAYTHKVVTMWYRAPELLA--------------------------STQEEQYHY
CDK11_c_Smoe    --CDPGPKFDTDPSRQWFRSLLVSEGGAFSDSFRVFHPEIAEAYTCWSQASGAEE--FNY


CDK11a_Hsap     STAVDMWSVGCIFGELLTQKP-----LFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPA
CDK11b_Hsap     STAVDMWSVGCIFGELLTQKP-----LFPGNSEIDQINKVFKELGTPSEKIWPGYSELPV
CDK11_Mmus      STAVDMWSVGCIFGELLTQKP-----LFPGKSDIDQINKIFKDLGTPSEKIWPGYNDLPA
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  NAAIDMWSLGCIMAEFLAKEP-----LFTGKSEIDQLDKIFKTLGTPNEKIWPNFVNLPG
CDK11_a-2_Smoe  TAAVDVWSLGCIMAELILNET-----LFQGTSEIDQLRRIKKMVWTAQL-EKPGF-----
CDK11_b-1_Smoe  NAAIDMWSLGCIMAEFLAKEP-----LFTGKSEIDQLDKIFKTLGTPNEKIWPNFVNLPG
CDK11_a-1_Smoe  TAAVDVWSLGCIMAELILNET-----LFQGTSEIDQLRRIKKMVWTAQL-EKPGF-----
CDK11_c_Smoe    GSRIDHVLI---------AGPCAGHCQCPDGSHENSSCDGFAECGTDMCDILLEFKRAK-


CDK11a_Hsap     VKKMTFSEHPYNNLRKRF--------GALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEY
CDK11b_Hsap     VKKMTFSEHPYNNLRKRF--------GALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEY
CDK11_Mmus      VKKMTFSEYPYNNLRKRF--------GALLSDQGFDLMNKFLTYYPGRRINAEDGLKHEY
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  VK-CNFVRQPYNRLREKFP-PVAFGGRPALSEKGYDLLNKLLTYDPSKRITAEEALNHEW
CDK11_a-2_Smoe  ----IFPAHKLSALRDRILYPAAQAGRPMLSEKGLDLLAQLLAYDPDKRISASAALAHPW
CDK11_b-1_Smoe  VK-CNFVRQPYNRLREKFP-PVAFGGRPALSEKGYDLLNKLLTYDPSKRITAEEALNHEW
CDK11_a-1_Smoe  ----IFPAHKLSALRDRILYPAAQAGRPMLSEKGLDLLAQLLAYDPDKRISANAALAHPW
CDK11_c_Smoe    LDTLPRSRSCYSALKHYLP--------FHHMKLHNWLLDLCLSFALLRKVSVRNGQ-QET


CDK11a_Hsap     FRETPLPIDPS-------------------------------------------------
CDK11b_Hsap     FRETPLPIDPS-------------------------------------------------
CDK11_Mmus      FRETPLPIDPS-------------------------------------------------
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  FDEVPLPKMKE-------------------------------------------------
CDK11_a-2_Smoe  FQEPPLPTPPP-------------------------------------------------
CDK11_b-1_Smoe  FDEVPLPKMKE-------------------------------------------------
CDK11_a-1_Smoe  FQEPPLPTPPP-------------------------------------------------
CDK11_c_Smoe    TEAVTKPIDRVLLSKHESSDKMSCTEVAVHGQSSSLTDEIQQSAESCDNNNCSEVAPCGE


CDK11a_Hsap     ------MFPTWPAKSEQQRV-KRG-TSPRPPEGGLGYSQLGDDDLKE-------------
CDK11b_Hsap     ------MFPTWPAKSEQQRV-KRG-TSPRPPEGGLGYSQLGDDDLKE-------------
CDK11_Mmus      ------MFPTWPAKSEQQRV-KRG-TSPRPPEGGLGYSQLGDDDLKE-------------
CDK11_d_Smoe    ------------------------------------------------------------
CDK11_b-2_Smoe  ------LMPTFPVRSDQDRRLRRAMKSPDPLEEQRRRELRGE------------------
CDK11_a-2_Smoe  ------PLPAPPLAATM-------------------------------------------
CDK11_b-1_Smoe  ------LMPTFPVRSDQDRRLRRAMKSPDPLEEQRRRELRGE------------------
CDK11_a-1_Smoe  ------PLPALPLAATM-------------------------------------------
CDK11_c_Smoe    SAILMDMSDETPTESSQQSL-EKLAAGWERLKSLMSRNLLSCKGHGETCVVRTVKKAGPN


CDK11a_Hsap     --TGFHLTTTNQGASAAGPGFSLKF
CDK11b_Hsap     --TGFHLTTTNQGASAAGPGFSLKF
CDK11_Mmus      --TGFHLTTTNQGASAAGPGFSLKF
CDK11_d_Smoe    -----------------------DD
CDK11_b-2_Smoe  ------------------FGAGVFG
CDK11_a-2_Smoe  ----------------------PLQ
CDK11_b-1_Smoe  ------------------FGAGVFG
CDK11_a-1_Smoe  ----------------------PLQ
CDK11_c_Smoe    LGRGFYVCTRAKGPAS---THKLGI