10580_Tthe MPSFIK-----------------------------------------PK-----------
22423_Tthe MLETCGQLMNFLNQAGLMKSLKA--------------FQDDMEIYIQSQQQQ---KTQNE
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe MADTVGSILDYLRQHHFLQAEAALKAELAGREVSNGLFSIDVDLGVQSNKVPAKELAEDA
10580_Tthe ------------------------------------------------------------
22423_Tthe NNPQD-----------GEKQTNSNLLKII---KKAIH-----------------------
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe SVPSDVQNEKLLVSEVADCQRNSTLVKYYMGVPKSTEQTTSASVQAGPELEVAEDKRRAT
10580_Tthe ------------------------------------------------------------
22423_Tthe ----------------------------QNNKKDVIPTFNQGAQDFQNKVQNINQKLFSQ
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe GSAGTENAAKVKVVGESSLESSNEGFWEQKDELLWVPGTKQGPQ--LGKVHPLDELGFSQ
10580_Tthe ------------------------------------------------------------
22423_Tthe EE-TEQIMERLMNKLVASPGLLEDEKLNSKIEKFFDNQTFQRMVEATDVMQDISNLSFTN
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe GRKSSQTHNDQKHKGAAR-------------HKSMEARSERSGPESTDEPQ-VSNIRSTR
10580_Tthe ------------------------------------------------------------
22423_Tthe SFLQKTKQEQQSILDENPPHF---------------------------------------
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe KEAAEDGKPEESCLASRPTSSANSSNQKGGQDKARGSGDGSERSSGFPRLPPVRLKSVEK
10580_Tthe ------------------------------------------------------------
22423_Tthe ---------------GMKQQPMNAPGLANQDFKLDQFNQQTISNQTNQQ--HNQLQQQQ-
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe IPDEWVAHCRVGSDADVEMDPLDASSFALGSFLDVPVGQDILSSGTKRCAAINRPSVSHG
10580_Tthe -QNDVSDFFQNSQSI------------------------------------NILEQLE--
22423_Tthe NVQNQQ-TDMNNGSEHMPLYPQQLQMNSPHNNQSDLNQKSEKQTEELKETQNKLEQLQNQ
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe IVEDPSASFANAGDG------------------------------------SAAEYPD--
10580_Tthe -------------------EPNFIDEYTDDDDPGFDLYEVP-EREFQ-------------
22423_Tthe DVQADAQNDLLQGILLQEDFMPNIDEYTDDDDPGFDLYEVP-QKDFV-------------
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe -------------------EYWDSDAYEDDDDPGYTRRPIDDEKEFLASEINYPSEEERA
10580_Tthe ------------------------------------------------------------
22423_Tthe ------------------------------------------------------------
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe RIEHNPAQQGTTYGKYDDDDRSYVESYFSGEEYYRGRDARDNNGDADVDALCGAADELSF
10580_Tthe ----------------------------------------------------KIAD--QL
22423_Tthe ----------------------------------------------------RVAQ--QL
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe RPHANDYDGQLLDSEELKQIRSEPAWQGFVVQGNAIRKDQAATTANDQDDFSREIRETYL
10580_Tthe ALK----------CDFPNRAT-SQVKKK--------------------------------
22423_Tthe AEK----------SDFPARAV-SSIPKK--------------------------------
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe AESSDGEVGSLQDCDFQGRNGFLDVEKRRQQCFKQGGPSSAEEEHDIVLQYYNRPWGHKA
10580_Tthe ------------------------------------------------------------
22423_Tthe --------------------------------------------------------EGYD
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe QANGCEEVDRNGSVETQLAEEQLGAFQFGGFSFPSPSSAGDVDGSRAESGRSLWSTREIS
10580_Tthe -HVDYKNMFLQNNDEDDESQVLQN-QQRN------------------ANNNNNPGQNQGN
22423_Tthe PHKEYSNPFANANPNQEDSQAMIK--------------------------------DIQK
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe SRGEEVDQFANGFVGPDDTLASWKRKSNESSPIISGGEDHELRLALSTHSTVSPGSTEDS
10580_Tthe ESTE-QNISNADQDLLSRRSNNQAKGYIYLPKFLKHPPSNDEFYPVQLDKAIYDCFDLKI
22423_Tthe QSSS-QAVDDQQQQKIVQQKNQVSKASIFLPDHIKFPQSNDSFYPIKYDKVIYDAFNLKV
DYRKP-2_Smoe ------------------------------------------------------------
DYRKP-1_Smoe LSVEEERVDD--ED-VDAQRDETEAAAAYDEEAIA---VHEHFHRLQAEEEEFETFDLKI
10580_Tthe ITDRERTGFEETKEFPIVINSIVAGRYQIMEYLGSAAFSKAIQCQDKQTGQMLCMKIIEN
22423_Tthe IFDRERTGFEETKEFPIVINSIIAGRYQVMEYLGSAAFSKAIQCLDLVTNRVMCMKIIEN
DYRKP-2_Smoe --------------------------------------------------MDVCMKIIKN
DYRKP-1_Smoe IHRKNRTGFEEDKDFQVLINSVIAGRYHVTEFLGAAAFSKAIQAHDLFTGMDVCMKIIKN
:*****:*
10580_Tthe NKDYFDQSIDEIKLLKYINYNGDVDEKNVLKVYDYFYHKEHLFIVTELLKDNLYEFYKFN
22423_Tthe NKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYFDYFYHKEHLFIITELLEENLYEFYKFN
DYRKP-2_Smoe NKDFFDQSLDEIKLLKYINKHDPADKYHILRLYDYFYHREHLFIVCELLRANLYEFHKYN
DYRKP-1_Smoe NKDFFDQSLDEIKLLKYINKHDPADKYHILRLYDYFYHREHLFIVCELLRANLYEFHKYN
***:****:******:*** :. .*: ::*: :*****:*****: ***. *****:*:*
10580_Tthe RENETQPYFTLGRLQKITQQILIGLDYIHSLRLIHCDLKPENILMKSYSKCQVKIIDFGS
22423_Tthe RENEQQRYFTVGRLQKITQQILVALDFIHSLRLIHCDLKPENILMKSKPKGEVKVIDFGS
DYRKP-2_Smoe RDSGGEVYFTMPRLQSITRQCLEALEFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGS
DYRKP-1_Smoe RDSGGEVYFTMPRLQSITRQCLEALEFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGS
*:. : ***: ***.**:* * .*:::*.* ************:** .: :**:**:**
10580_Tthe SCFIHDHLSSYVQSRSYRAPEVILGCKYDYKIDMWSLGCILAELWTGNVLFQNDTVQGLL
22423_Tthe SCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDIWSLGCILAELWTGNVLFQNDNIQGLL
DYRKP-2_Smoe SCFQSDHLCSYVQSRSYRAPEVILGLPYDQKIDIWSLGCILAELCSGNVLFQNDSLATLL
DYRKP-1_Smoe SCFQSDHLCSYVQSRSYRAPEVILGLPYDQKIDIWSLGCILAELCSGNVLFQNDSLATLL
*** ***.**************:* ** :**:********** :********.: **
10580_Tthe ARVIGIIGPIPEWMFQEGRLVNNFFTNKRLLYQDVFEEGEPSQNINDTSDMPGRRQKSGK
22423_Tthe ARVIGIIGPFPEWMMKEGRLVQNFFTREKLLYMEVFEEADQSQAIGDQQDGQRQKIKTGK
DYRKP-2_Smoe ARVVGIIGPLDPEMVARGRESYKFLTKNSKLYE--------------------RNQETSR
DYRKP-1_Smoe ARVVGIIGPLDPEMVARGRESYKFLTKNGKLYE--------------------RNQETSR
***:*****: *. .** :*:*.: ** :. ::.:
10580_Tthe IQILVPKKSNLRARLKTDDLMFLDFVKSLLQIDRTRRPSAKEALQHPWLTQSHYQEDQ
22423_Tthe IQILVPKHSNLKARLRTEDHLFIDFVRQCLQIDFTRRPTAKEALSHPWFKLKY-PDGL
DYRKP-2_Smoe MEYLIPKKTTLAHRLPMGDQGFLEFVAFLLQINPKNRPSAAEALKHPWLSYPYEPISS
DYRKP-1_Smoe MEYLIPKKTTLAHRLPMGDQGFLEFVAFLLQINPKNRPSAAEALKHPWLSYPYEPISS
:: *:**::.* ** * *::** ***: ..**:* ***.***:. : .