Protein (view, download) , Domain (view, download)
MRCKb_Hsap       MSAK-----------------------------------------------------VRL
MRCKa_Hsap       MSGE-----------------------------------------------------VRL
gek_Dmel         MEYESSEISDI---------------------TT------G-------------SCKKRL
MRCKb_Mmus       MSAK-----------------------------------------------------VRL
MRCKa_Mmus       MSGE-----------------------------------------------------VRL
DMPK2_Mmus       ME-------------------------------------------------------QRL
DMPK1_Mmus       MSAE-----------------------------------------------------VRL
K08B12.5_Cele    MAEPPPD---------------------------------D-------------SAPVRL
DMPK2_Hsap       ME-------------------------------------------------------RRL
DMPK1_Hsap       MGGHFWPPEPYT------------------VFMWGSPWEAD-------------SPRVKL
MRCK_Spur        MPWPVIAVHRARPQARPGPGGSVFAIGQWAWAVLFSPLRPDRPYGKVLQASAGTGGDISE
CC1G_07309_Ccin  MSLE-----------------------------------------------------WVY
AqueK005_Aque    MDKQTP--------------------------------------------------DSKA
                 *

MRCKb_Hsap       -------------------KKLEQLLLDGPW----------R------------------
MRCKa_Hsap       -------------------RQLEQFILDGPA----------Q------------------
gek_Dmel         -------------------TFLKCILSDTTSDQKWAAEFGED------------------
MRCKb_Mmus       -------------------KKLEQLLLDGPW----------R------------------
MRCKa_Mmus       -------------------RQLEQFILDGPA----------Q------------------
DMPK2_Mmus       -------------------RALEQLVRG--------------------------------
DMPK1_Mmus       -------------------RQLQQLVL---------------------------------
K08B12.5_Cele    -------------------KTLENIYMDGPS-----------------------------
DMPK2_Hsap       -------------------RALEQLARG--------------------------------
DMPK1_Hsap       -------------------RGREKGRQ---------------------------------
MRCK_Spur        TQVKKFLGGVRSFFCEAVSYALSRLPLDEPV----------LQHATFVDWHQKMEASIDD
CC1G_07309_Ccin  -------------------RF---------------------------------------
AqueK005_Aque    -------------------RRLEIGIRER----------RPE------------------


MRCKb_Hsap       -------------------------NESALSVETLLDVLVCLYTEC--------------
MRCKa_Hsap       ------------------------TNGQCFSVETLLDILICLYDEC--------------
gek_Dmel         ------------------------TEGHQFSLDYLLDTFIVLYDEC--------------
MRCKb_Mmus       -------------------------NDSALSVETLLDVLVCLYTEC--------------
MRCKa_Mmus       ------------------------TNGQCFSVETLLDILICLYDEC--------------
DMPK2_Mmus       ------------------------EAGGSPGLDGLLDLLLGVHQEL--------------
DMPK1_Mmus       -------------------------DPGFLGLEPLLDLLLGVHQEL--------------
K08B12.5_Cele    ------------------------KKPEALSFETLIDSLICLYDEC--------------
DMPK2_Hsap       ------------------------EAGGCPGLDGLLDLLLALHHEL--------------
DMPK1_Hsap       ------------------------TEGGAFPL----------------------------
MRCK_Spur        DVLFFIDSNADAERVFSSIGLNKTETRNALHLDGTLSSIMTIKMAASEPCYRFEPPAEGL
CC1G_07309_Ccin  -------------------------TISCVSIQ----------IDL--------------
AqueK005_Aque    ------------------------DRSNNFCVESLIDALVVLYDEC--------------
                                                .

MRCKb_Hsap       ----SHSALRR-DKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMK
MRCKa_Hsap       ----NNSPLRR-EKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLK
gek_Dmel         ----SNSSLRR-EKGVSDFLKLSKPFVHIVRKLRLSRDDFDILKIIGRGAFGEVCVVQMI
MRCKb_Mmus       ----SHSALRR-DKYVAEFLEWAKPFTQLVKDMQLHREDFEIIKVIGRGAFGEVAVVKMK
MRCKa_Mmus       ----NNSPLRR-EKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLK
DMPK2_Mmus       ----SSAPLRR-ERNVAQFLSWASPFVTKVKELRLQRDDFEILKVIGRGAFGEVAVVRQR
DMPK1_Mmus       ----GASHLAQ-DKYVADFLQWVEPIAARLKEVRLQRDDFEILKVIGRGAFSEVAVVKMK
K08B12.5_Cele    ----CNSTLRK-EKCIAEFVESVKTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMR
DMPK2_Hsap       ----SSGPLRR-ERSVAQFLSWASPFVSKVKELRLQRDDFEILKVIGRGAFGEVTVVRQR
DMPK1_Hsap       ----VSSALSGDPRFFSPTTPPAEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMK
MRCK_Spur        LLALLMQTLRY-TVYMFMYEEGAKLPVKKVKDLRLHKEDFETLKIIGRGAFGEVAVVKLK
CC1G_07309_Ccin  ---------------------STTAKTAEIDSLRFQDKDLQVVGTLEYGQFGVIEVVTCK
AqueK005_Aque    ----CSSNQKR-ERTVVEFVERVKPVIDRVKECRLTADDFEVLEVIGRGAFGEVKVVRLK
                                                . ::  .*:: :  :  * *. : **

MRCKb_Hsap       NTERIYAMKILNKWEMLKRAETACFREERDVLVNG---DCQWITALHYAFQDENHLYLVM
MRCKa_Hsap       NADKVFAMKILNKWEMLKRAETACFREERDVLVNG---DNKWITTLHYAFQDDNNLYLVM
gek_Dmel         STEKVYAMKILNKWEMLKRAETACFREERDVLVFG---DRQWITNLHYAFQDNINLYLVM
MRCKb_Mmus       NTERIYAMKILNKWEMLKRAETACFREERDVLVNG---DCQWITALHYAFQDENYLYLVM
MRCKa_Mmus       NADKVFAMKILNKWEMLKRAETACFREERDVLVNG---DSKWITTLHYAFQDDNNLYLVM
DMPK2_Mmus       GSGQIFAMKMLHKWEMLKRAETACFREERDVLVKG---DSRWVTALHYAFQDEEYLYLVM
DMPK1_Mmus       QTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKG---DRRWITQLHFAFQDENYLYLVM
K08B12.5_Cele    GVGEIYAMKILNKWEMVKRAETACFREERDVLVYG---DRRWITNLHYAFQDEKNLYFVM
DMPK2_Hsap       DTGQIFAMKMLHKWEMLKRAETACFREERDVLVKG---DSRWVTTLHYAFQDEEYLYLVM
DMPK1_Hsap       QTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNG---DRRWITQLHFAFQDENYLYLVM
MRCK_Spur        NSDDVFAMKLLNKWEMLKRAETACFVEERDVLVHG---DSRWITNLHYAFQDDDFLYLVM
CC1G_07309_Ccin  LNNRVYVRKSIEKKFAMRTREQCSPQTERNILVAASLTESPWAPHLLAAYQMPTHLHLVM
AqueK005_Aque    STNKVYALKVLNKAEMLQRQTTACFKEERDVLVFG---NRDWITKLHYAFQDKNNLYFVM
                     ::. * :.*   ::    ..   **::** .   :  * . *  *:*    *::**

MRCKb_Hsap       DYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGH
MRCKa_Hsap       DYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGH
gek_Dmel         DYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQIRYVHRDIKPDNVLLDKRGH
MRCKb_Mmus       DYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGH
MRCKa_Mmus       DYYVGGDLLTLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGH
DMPK2_Mmus       DYYAGGDLLTLLSRFEDRLPPELAQFYLAEMVLAIHSLHQLGYVHRDVKPDNILLDMNGH
DMPK1_Mmus       EYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGH
K08B12.5_Cele    DYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGH
DMPK2_Hsap       DYYAGGDLLTLLSRFEDRLPPELAQFYLAEMVLAIHSLHQLGYVHRDVKPDNVLLDVNGH
DMPK1_Hsap       EYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGH
MRCK_Spur        DYYSGGDLLTLISKFDDRLPEDMARFYVAEMVLAIDSVHMLRYVHRDIKPDNVLLDKHGH
CC1G_07309_Ccin  DYAEGGNLWDVLESSTGKISESDLKWWVPQAVSAIHWCHTQGFAHRDIKPHNFVLTKDSR
AqueK005_Aque    DYYLGGDVLTLLSKFEDRLTEDMVKFYASEMILAIHSIHDLGYVHRDIKPDNVLIGKDGH
                 :*  **::  ::.    ::. .  :::  : : **.  *   :.***:**.*.::   .:

MRCKb_Hsap       IRLADFGSCLKMNDDGTVQ--------SSVAVGTPDYISPEILQAMED------------
MRCKa_Hsap       IRLADFGSCLKLMEDGTVQ--------SSVAVGTPDYISPEILQAMED------------
gek_Dmel         VRLADFGSCLRLDKDGTVQ--------SNVAVGTPDYISPEILRAMED------------
MRCKb_Mmus       IRLADFGSCLKMNDDGTVQ--------SSVAVGTPDYISPEILQAMED------------
MRCKa_Mmus       IRLADFGSCLKLMEDGTVQ--------SSVAVGTPDYISPEILQAMED------------
DMPK2_Mmus       IRLADFGSCLRLNNNGMVD--------SSVAVGTPDYISPEILQAMEE------------
DMPK1_Mmus       IRLADFGSCLKLQPDGMVR--------SLVAVGTPDYLSPEILQAVGGGP----------
K08B12.5_Cele    IRLADFGSCLRILADGSVA--------SNVAVGTPDYISPEILRAMED------------
DMPK2_Hsap       IRLADFGSCLRLNTNGMVD--------SSVAVGTPDYISPEILQAMEE------------
DMPK1_Hsap       IRLADFGSCLKLRADGTVR--------SLVAVGTPDYLSPEILQAVGGGP----------
MRCK_Spur        IRLADFGSCLRMLPDNTVM--------SNVAVGTPDYISPEILRAMED------------
CC1G_07309_Ccin  VQLIDFGSAAPLLPPGPDGSQKLARKHCLVPCGTCDYISPEILEAHEQALVALEMDDEDE
AqueK005_Aque    IRLADFGSCLKMDSNRKVN--------STTAVGTPDYISPEILQAMED------------
                 ::* ****.  :               . .. ** **:*****.*

MRCKb_Hsap       ------GMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVT
MRCKa_Hsap       ------GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVT
gek_Dmel         ------GKGRYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQET
MRCKb_Mmus       ------GMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVT
MRCKa_Mmus       ------GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVT
DMPK2_Mmus       ------GKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPADVT
DMPK1_Mmus       ------GAGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPLADT
K08B12.5_Cele    ------GRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPDDEI
DMPK2_Hsap       ------GKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPDVP
DMPK1_Hsap       ------GTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE
MRCK_Spur        ------GKGRYGPECDWWSLGVCMYEMLFGETPFYAESLVETYGKIMNHKNQFDFPPETE
CC1G_07309_Ccin  NPLVIEDPEGYGVETDWWSLGAMLYEMAYGVAPFFANEIRHTYQRILNHEKCLRFED---
AqueK005_Aque    ------GRGVYGPECDWWSLGICIYEMLFGETPFYAESLLQTYSKIMQHKTLFSFPSDED
                       .   ** : ***:**   **: :* :**:::   .** :*: :.  : :

MRCKb_Hsap       ---DVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSS-
MRCKa_Hsap       ---DVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSS-
gek_Dmel         LNYKVSETSQDLLCKLICIPENRLGQNGIQDFMDHPWFVGIDWKNIRQGPAPYVPEVSS-
MRCKb_Mmus       ---DVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSS-
MRCKa_Mmus       ---DVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSS-
DMPK2_Mmus       ---DVPASAQDLIRQLLCRQEERLGRGGLDDFRKHPFFEGVDWERLATSTAPYIPELRG-
DMPK1_Mmus       ---VVPEEAQDLIRGLLCPAEIRLGRGGAGDFQKHPFFFGLDWEGLRDSVPPFTPDFEG-
K08B12.5_Cele    -DWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSS-
DMPK2_Hsap       ---DVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRG-
DMPK1_Hsap       ---GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEG-
MRCK_Spur        EEVAISEDAKDLILSLICSAEARLGRNGLQDFKDHPFFNDIDWQNIRNMTPPYVPDVKS-
CC1G_07309_Ccin  ---GVSFELQDLLARLLTRAEKRLGRRNIMEITDHPFFRGTDWTSLSSQSAP--PDLHLP
AqueK005_Aque    -SIVVSKDAKNLIKNLICDAEERLGQSGIDDFKKHPFFEGIDWDNIRSQTPPYIPEFTS-
                     :.   ::::  *:   : *:*: .  ::  *.:* . :*  :    .*  *:.

MRCKb_Hsap       --------PSDTS-----NFDVD--DDVLRN--------------------------TEI
MRCKa_Hsap       --------PTDTS-----NFDVD--DDCLKN--------------------------SET
gek_Dmel         --------PTDTS-----NFDVD--DNDVRL--------------------------TDS
MRCKb_Mmus       --------PSDTS-----NFDVD--DDMLRN--------------------------IEI
MRCKa_Mmus       --------PTDTS-----NFDVD--DDCLKN--------------------------SET
DMPK2_Mmus       --------PMDTS-----NFDVD--DDTLNR--------------------------PET
DMPK1_Mmus       --------ATDTC-----NFDVV--EDRLTAMVS---------------------GGGET
K08B12.5_Cele    --------PEDTS-----NFDVDVCEDDFTP--------------------------CET
DMPK2_Hsap       --------PMDTS-----NFDVD--DDTLNH--------------------------PGT
DMPK1_Hsap       --------ATDTC-----NFDLV--EDGLTAMVS---------------------GGGET
MRCK_Spur        --------ATDTS-----NFDVD--EADLRN--------------------------SEV
CC1G_07309_Ccin  QFTYSIPQPTEAANHVPSPMDVD--DKSESYSQGFAFSAFFQSSHGSVSHNASFLRHSIT
AqueK005_Aque    --------DTDTR-----NFEPY--EPDDPG--------------------------HDP
                           ::       ::    :

MRCKb_Hsap       LPPGSHTGFSGLHLPFIGFTFTTE--SCFSDRGSLKSIMQSNTLTKDEDVQRDLEHSLQM
MRCKa_Hsap       MPPPTHTAFSGHHLPFVGFTYTSS--CVLSDRSCLRVTAGPTSLDLDVNVQRTLDNNLAT
gek_Dmel         IPPSANPAFSGFHLPFIGFTFSLTSSSTLDSKKNQSSGFGDDTLDTISSPQLA-------
MRCKb_Mmus       LPPGSHTGFSGLHLPFIGFTFTTE--SCFSDRGSLKSMTQSNTLTKDEDVQRDLENSLQI
MRCKa_Mmus       MPPPTHTAFSGHHLPFVGFTYTSS--CVLSDRSCLRVTAGPTSLDLDVSVQRTLDNNLAT
DMPK2_Mmus       LPPSSHGAFSGHHLPFVGFTYTSG--SPFDVQSS-----------------------ELM
DMPK1_Mmus       LSDMQEDMPLGVRLPFVGYSYCCM--AFRDNQVPDPTPM---------------------
K08B12.5_Cele    QPPRVLAAFTGNHLPFVGFSYTHG--SLLSDARSLTDEIRAIA----QRCQ--GDAELME
DMPK2_Hsap       LPPPSHGAFSGHHLPFVGFTYTSG--SHSPESSS-----------------------EAW
DMPK1_Hsap       LSDIREGAPLGVHLPFVGYSYSCM--ALRDSEVPGPTPM---------------------
MRCK_Spur        LPPSSHAAFTGNHLPFLGYTFTRN--SNLSDLGKLADVKEVIS----SGIKEGVVDSAQV
CC1G_07309_Ccin  PRPPRPSPRDDPSSAFIGFSWGPLI-DAFPDQP---LGVSQNSDQR--------------
AqueK005_Aque    TPPN-LTAL-TLHLPFVGFTFTSG--SALSDRPPLPSLVTR-------------------
                               .*:*:::

MRCKb_Hsap       EAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSR--ALSNSNRDKE--IKK-LNEEIE
MRCKa_Hsap       EAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTV-DGPLTASKDLE--IKN-LKEEIE
gek_Dmel         ----------------------------------IL---P--------------------
MRCKb_Mmus       EAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSTR--ALGNSNRDKE--IKR-LNEELE
MRCKa_Mmus       EAYERRIKRLEQEKLELTRKLQESTQTVQALQYSTV-DGPLTASKDLE--IKS-LKEEIE
DMPK2_Mmus       AAPEGTPHCVEQVKVELSHKCQEPLH---------------GPLQPQE--LVR-LQKEVQ
DMPK1_Mmus       --------ELEALQL---------------------------------------------
K08B12.5_Cele    KSVDGFMVELENEKAELVQKLKEAQTI-IAQHVAENPRSEEDRNYEST--IAQ-LKDEIQ
DMPK2_Hsap       AALERKLQCLEQEKVELSRKHQEALH---------------APTDHRE--LEQ-LRKEVQ
DMPK1_Hsap       --------ELEAEQL---------------------------------------------
MRCK_Spur        ESLERRINKLETEKTELTNRVSELKSS--------------GGGENDE--VRR-LQEEIK
CC1G_07309_Ccin  --------------------------HL-----SPI--PSTGPATTPTFPVVTPGFLTAD
AqueK005_Aque    ----------E----------QETG-IITQ--L------PSGPS--EE--EER-LRAEVK


MRCKb_Hsap       RLKNKIADSNRLER-QLEDTV-----ALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQL
MRCKa_Hsap       KLRKQVTESSHLEQ-QLEEAN-----AVRQELDDAFRQIKAYEKQIKTLQQEREDLNKEL
gek_Dmel         --------------------------SNNSETPVDSVQLKALNDQLAALKQEKAELSKQH
MRCKb_Mmus       RMKSKMADSNRLER-QLEDTV-----TLRQEHEDSTHRLKGLEKQYRLARQEKEELHKQL
MRCKa_Mmus       KLRKQVAEVNHLEQ-QLEEAN-----SVRRELDDAFRQIKASEKQIKTLQQEREELNKEL
DMPK2_Mmus       VLQEKLAETLRDSKASLSQTD-----GLHA----------RSPAPNIQLQQEKDRLQQEL
DMPK1_Mmus       ----PVSD------------------------------------------LQGLDLQPPV
K08B12.5_Cele    ILNKRLEDEALAQQ-QQKPKD-----EIVAESE---KKLKELKERNKQLVMEKSEIQREL
DMPK2_Hsap       TLRDRLPEMLRDKA-SLSQTD-----GPPA----------GSPGQDSDLRQELDRLHREL
DMPK1_Hsap       ----LEPH------------------------------------------VQAPSLEPSV
MRCK_Spur        SFKSRIAASEAESK-NTRDSYQAMAKEMQSAEDEKSSKIKTLERTSKLIKQEKENLEREV
CC1G_07309_Ccin  ALATPLP-SNRFAD-QHPFV----------------------------------------
AqueK005_Aque    SLKDELDKSRR-------GTL-----SSQKGHDDQASKMKTLERAVRSLKSEKNSLTEQV


MRCKb_Hsap       VEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVAT
MRCKa_Hsap       VQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVM
gek_Dmel         NEVFERLKTQDSELQDAISQRNIAMMEYSEVTEKLSELRNQKQKLSRQVRDKEEELDGAM
MRCKb_Mmus       VEASERLKSQTKELKDAHQQRKRALQEFSELNERMSELRSLKQKVSRQLRDKEEEMEVAM
MRCKa_Mmus       VQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVM
DMPK2_Mmus       TEAQAALRVQDAELCQAQNRQEEFLQRLWEAQEREAAAASQIQALNS-------------
DMPK1_Mmus       SPPDQVAEEA--------------------------------------------------
K08B12.5_Cele    DNINDHLDQVLVEKATVVQQRDDMQAELADV-----------------------------
DMPK2_Hsap       AEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQTRALSS-------------
DMPK1_Hsap       SPQDETAEVA--------------------------------------------------
MRCK_Spur        EEIHERNRQLNKEMKEAKSQGKLAMQEFTEINERYADIMSQKQKLSRDLRDKEEEIEVVS
CC1G_07309_Ccin  ----------------------TPVRPYTISNSPMN----------------------TI
AqueK005_Aque    SDLKESLAAKEKELKEGNKRYRESQDELNRISDKMTDYRSQKRELSRALREKEEEYDEIA


MRCKb_Hsap       QKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQG
MRCKa_Hsap       QKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQI
gek_Dmel         QKNDSLRNELRKSDKTRRELELHIEDAVIEAAKEKKLREHAEDCCRQLQMELRKGSSSVE
MRCKb_Mmus       QKIDSMRQDLRKSEKSRKELEARLEDAAAEASKERKLREHSESFCKQMERELEALKVKQG
MRCKa_Mmus       QKAESLRQELRRAERAKKELEVHTEALIAEASKDKKLREQSEHYSKQLENELEGLKQKQI
DMPK2_Mmus       --------QLEEAWVVRRELEGQVTTLSQEVT----------------------------
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    -----------------------GDSLLTEKDSVKRLQDEAEKAKKQVADFEEKLKEI-E
DMPK2_Hsap       --------QLEEARAAQRELEAQVSSLSRQVT----------------------------
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        QKVDSQRADIRKHEQANKELEALQEDFQVEIAREKKLRQQSDQNIKQLQDELEGLKVNSV
CC1G_07309_Ccin  RRTNTIRRTVGRREVSDREAMKQLVDCIGMSARK--------------------------
AqueK005_Aque    SKVDSYRKTAKESEREKRSLLNELDDAKAAVSQEKRQKNRLEKLKQELEDEISTLRSKHR


MRCKb_Hsap       -GRGAGA-TLEHQQEISK-IKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQ
MRCKa_Hsap       -SYSPGVCSIEHQQEITK-LKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQ
gek_Dmel         -TTMP------LSISSEM-SSYEIERLELQFSEKLSHQQTRHNMELEALREQFSELENAN
MRCKb_Mmus       -GRGPGA-ASEHQQEISK-IRSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQ
MRCKa_Mmus       -SYSPGICSIEHQQEITK-LKTDLEKKSIFYEEEISKREGIHASEIKNLKKELHDSEGQQ
DMPK2_Mmus       -----------------R-LQGQCKQ-------ESSQAKTVHAAPETNGIG-SPEGQSQE
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    --TEKIA-LIKKQEEVTIEARKSVETDDHLSE------------EVVAAKNTIASLQATN
DMPK2_Hsap       -----------------Q-LQGQWEQRL----EESSQAKTIHTASETNGMG-PPEGGPQE
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        -GRAKPD-TDKYEKEVAR-LKQEMEKKEVQYAEGVAKEKSRHTIEEKILKEQVNENEDKI
CC1G_07309_Ccin  ------------------------------------------------------------
AqueK005_Aque    RDTSTGQDTQELQKNIEK-LQAQLQEKDSDHSEAVKSLEAKHIAEVQKLKELLATSESTN


MRCKb_Hsap       LALQKEILMLKDKLEKSKRERHNE-MEE--AVGTIKDKYERERAMLFDENKKLTAENEKL
MRCKa_Hsap       LALNKEIMILKDKLEKTRRESQSE-REE--FESEFKQQYEREKVLLTEENKKLTSELDKL
gek_Dmel         LALTKELQQTQERLKYTQMESITD-SAE--TLLELKKQHDLEKSSWFEEKQRLSSEVNLK
MRCKb_Mmus       LALQKEVLMLKDKLEKSKRERHSE-MEE--AIGTVKDKYERERAMLFDENKKLTAENEKL
MRCKa_Mmus       LALNKEILVLKDKLEKTRRESQSE-REE--FENEFKQQYEREKVLLTEENKKLTSELDKL
DMPK2_Mmus       AQLRKEVAALREQLEHACSQGISVGKEE--VL-----------CRLQEENQRLSREQERL
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    EERETEIKKLKQRMDEERASHTAQ-SEQ--EMKQLEAHYERAQKMLQDNVEQMNVE----
DMPK2_Hsap       AQLRKEVAALREQLEQAHSHRPSG-KEE--AL-----------CQLQEENRRLSREQERL
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        VSMRREITSLQDKLGRLQTTSTED-QHAKMKMDDMKRNYERTKALINDDKTKLSQDLDKT
CC1G_07309_Ccin  ------------------------------------------KVLESGRKPKILTSYNLS
AqueK005_Aque    TELHNENNDLQVRLTKVRNRTISE-LNE--GMKEKVDKYEKDKIQLSEEKRELSLQVESL


MRCKb_Hsap       CSFVDKLTAQNRQLEDELQDLAAKKESVA---HWEAQIAEIIQWVSDEKDARGYLQALAS
MRCKa_Hsap       TTLYENLSIHNQQLEEEVKDLADKKESVA---HWEAQITEIIQWVSDEKDARGYLQALAS
gek_Dmel         SKSLKELQAE---DDEIFKELRMKREAIT---LWERQMAEIIQWVSDEKDARGYLQALAT
MRCKb_Mmus       CSFVDKLTAQNRQLEDELQDLASKKESVA---HWEAQIAEIIQWVSDEKDARGYLQALAS
MRCKa_Mmus       TSLYESLSLRNQHLEEEVKDLADKKESVA---HWEAQITEIIQWVSDEKDARGYLQALAS
DMPK2_Mmus       AGELELELQSKQRLE------GERRETES---NWEAQIADILSWVNDEKVSRGYLQALAT
DMPK1_Mmus       -------------------DLVAVPAP---VAEAETT-----------------------
K08B12.5_Cele    ----------NRGLRDEIEKLSQQMAALPRGGLNEQQLHEIFNWVSEEKATREEMENLTR
DMPK2_Hsap       EAELAQEQESKQRLE------GERRETES---NWEAQLADILSWVNDEKVSRGYLQALAT
DMPK1_Hsap       ---------------------VPAAVP---AAEAEAE-----------------------
MRCK_Spur        LLEKERLQRELRLSEEKLEEMSRNKDSVA---HWEAQIAEIIQWVSDEKDARGYLQALAS
CC1G_07309_Ccin  RSLRRRPSVRSFSLTDKTTDGAPNTGAT--------------NSNGTRKELRFYPTVMPI
AqueK005_Aque    TTKLEESKKIQQQQEEDLKDIKNQKELLS---QWEHQIAEIVQLVSDEKNARSYLQTVAK


MRCKb_Hsap       KMTEELEALRSS---SLG--SRTLDPLWKVRRSQKLDMSARLELQSALEAEIRAKQLVQE
MRCKa_Hsap       KMTEELEALRNS---SLG--TRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQE
gek_Dmel         KMTEELEYLKHVGTF--N-NNGVDNKNWRNRRSQKLDKMELLNLQSALQREIQAKNMISD
MRCKb_Mmus       KMTEELETLRSS---SLG--SRTLDPLWKVRRSQKLDMSARLELQSALEAEIRAKQLVQE
MRCKa_Mmus       KMTEELEALRNS---SLG--TRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQE
DMPK2_Mmus       KMAEELESLRNVGTQTLP--TRPLDHQWKARRLQKMEASARLELQSALEAEIRAKQSLQE
DMPK1_Mmus       --------------------------------------VTLQQLQEALEEEVLTRQSLSR
K08B12.5_Cele    KITGEVESLKNNSPLTTSNYIQNTPSGWGSRRMNNVARKDGLDLQRQLQAEIDAKLKLKA
DMPK2_Hsap       KMAEELESLRNVGTQTLP--ARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQE
DMPK1_Hsap       --------------------------------------VTLRELQEALEEEVLTRQSLSR
MRCK_Spur        KMTDELESIKVSGIVG-----AAREKSWQSR-----------------------------
CC1G_07309_Ccin  PMTEYTDD-----GG-----TE--------------------------------------
AqueK005_Aque    GLVEDVESLRASS---SS--IGKQKEVWVERRTLRRDKLERVEMQQNFENELRAKQRVEE


MRCKb_Hsap       ELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKMEEK------FRADTGLKLPDFQD
MRCKa_Hsap       ELNKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEE-------LRSEKGIEHQDSQH
gek_Dmel         ELSQTRSDLISTQKEVRDYKKRYDSILHDFQKKETELRDL------Q--KGGLEYSESFL
MRCKb_Mmus       ELRKVKDSSLAFESKLKESEAKNRELLEEMQSLRKRMEEK------FRADTGLKLPDFQD
MRCKa_Mmus       ELNKVKASNILTECKLKDSEKKNLELLSEIEQLIKDTEE-------LRSEKGIEHQDSQH
DMPK2_Mmus       QLTQVQEAQRQAERRLQEAEKQSQALQQEVAELREELQAR------GPGD--ARPSTSLI
DMPK1_Mmus       ELEAIRTANQNFSSQLQEAEVRNRDLEAHVRQLQERMEML-------QAPGA-A-AI---
K08B12.5_Cele    ELKNSQEQYLTSAARLDDTEKRMASLMREVAMLKQQKNIE------NSSDSAFS-ST-MG
DMPK2_Hsap       RLTQVQEAQLQAERRLQEAEKQSQALQQELAMLREELRAR------GPVD--TKPSNSLI
DMPK1_Hsap       EMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELL-------QAEGA-T-AV---
MRCK_Spur        -------------SKLRSSEARNTELTDEVAKLTTSVTELEQQLQELKQNAADK-AGSNL
CC1G_07309_Ccin  ------------------------------------------------------------
AqueK005_Aque    ELTHIRTQLAHTESDVVQLKAQIESLQKENEKLNKENQK-------YRMGLGSRNDSFTT


MRCKb_Hsap       S-----IFE--YF-NT--APLAHDL---TFRTSSASE----------QETQAPKPE----
MRCKa_Hsap       S-----FLA--FL-NT--PTDALDQFEDSFSSSSSSLIDFLDDTDPVENTYVWNPSVKFH
gek_Dmel         NKSTHHGLSSAFFRDMSKNSEIIDSAE-SFGNESG------DNFTPNFFQ-SGNSGMLFN
MRCKb_Mmus       S-----IFE--YF-NT--APLAHDL---TFRTSSASD----------QETQASKMD----
MRCKa_Mmus       S-----FLA--FL-NT--PTDALDQFEDSLSSSSSSLIDFLDDTDPVDNTYIRNPSIKFY
DMPK2_Mmus       P-----LLS--FW-NT--EKD---SAK---------------------------------
DMPK1_Mmus       -----------------------------------------------------T------
K08B12.5_Cele    R-----G-D--LM----------ISMNNDYEMSNSSLMR--------QEMISRQ------
DMPK2_Hsap       P-----FLS--FR-SS--EKD---SAK---------------------------------
DMPK1_Hsap       -----------------------------------------------------T------
MRCK_Spur        S-----F-A--FL----------DNLDR-YLDVDTK-LN--------FDF-SD-------
CC1G_07309_Ccin  ------------------------------------------------------------
AqueK005_Aque    S-----IF-----H---------------H--QSGNQ-----------------------


MRCKb_Hsap       -ASPSMSVAA--SE--QQEDMARPPQRPSA---VPLPT-----TQALALAGPKP-KAHQF
MRCKa_Hsap       IQSRSTSPSTS-SE---AEPVKTVDSTPLS---VHTPTLRKKGCPGSTGFPPKR-KTHQF
gek_Dmel         -YEPKYAGKNN-KDHSSMKEASVSDL----SRE-ESDQLV---KESQKKVPGNT-AIHQF
MRCKb_Mmus       -LSPSVSVATS-TE--QQEDMARPQQRPSP---VPLPS-----TQALAMAGPKP-KAHQF
MRCKa_Mmus       IQSRPTSPSTA-SE---AEPVKIADCAPLP---AHTPTLRKKGCPASTGFPPKR-KTHQF
DMPK2_Mmus       --DPGNSGEGP-RS--GAEAELRPEGRRSLRMGSVFPRVPAATTTPAEGPPAKP-GSHTL
DMPK1_Mmus       -GVP--------------SPRATDPP----SHL-DGPPAVAVGQCPLVGPGPMH-RRHLL
K08B12.5_Cele    -STPSYENAILLHD--HQVPKRVDDL----RYK-QKPMKTASGIFSPVSISAME-RGHNF
DMPK2_Hsap       --DPGISGEAT-RH--GGEPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKP-GSHTL
DMPK1_Hsap       -GVP--------------SPRATDPP----SHL-DGPPAVAVGQCPLVGPGPMH-RRHLL
MRCK_Spur        -MDPPERDT---GA--PVEPVATDDK----SVH-S--SGTSSGETPP--PTPKH-KTHKF
CC1G_07309_Ccin  ----------------------------------------------S-DNPSQPTRTSRL
AqueK005_Aque    -------LETS-TR---AAPQ-----KPK-----------------VITGTERE-GTHEL
                                                                            :

MRCKb_Hsap       SIKSFSSPTQCSHCTSLMVGLIR----QGYACEVCSFACHVSCKDGAPQVCPIPPEQSKR
MRCKa_Hsap       FVKSFTTPTKCHQCTSLMVGLIR----QGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKG
gek_Dmel         LVRTFSSPTKCNHCTSLMVGLTR----QGVVCEICGFACHTICCQKVPTTCPVPMDQTKR
MRCKb_Mmus       SIKSFPSPTQCSHCTSLMVGLIR----QGYACEVCAFSCHVSCKDSAPQVCPIPPEQSKR
MRCKa_Mmus       FVKSFTAPTKCHQCTSLMVGLIR----QGCSCEVCGFSCHITCVNKAPTVCPVPPEQTKG
DMPK2_Mmus       RPRSFPSPTKCLRCTSLMLGLGR----QGLGCDTCGYFCHSACASQAP-PCPVPPELLRT
DMPK1_Mmus       LPARIP-----------------------------------------------------R
K08B12.5_Cele    ERMKIKTPTKCGHCTSILIGLDR----QGLFCQSCQYACHVSCAERVSQSCPVPEEE-RR
DMPK2_Hsap       RPRSFPSPTKCLRCTSLMLGLGR----QGLGCDACGYFCHTTCAPQAP-PCPVPPDLLRT
DMPK1_Hsap       LPARVP-----------------------------------------------------R
MRCK_Spur        MITNFQVPAKCAHCTSLMLGQSR----QGMMCEVCHFACHVACAEKAPSMCPISQQQMAK
CC1G_07309_Ccin  PPLTLAPAMTNGRSNSRMLGDSDSSETGGYGYINYPYYSNSECSESEGPPSPSPSP---R
AqueK005_Aque    VVRSFDSPTKCDACTSVMFGLVR----QGMMCKNCQMSCHVQCKDKVLATCPLPPGQAKM
                     .

MRCKb_Hsap       PLGV---------------DV-----------QRGIGTAYKGHVKVPKPT-GVKKGWQRA
MRCKa_Hsap       PLGI---------------DP-----------QKGIGTAYEGHVRIPKPA-GVKKGWQRA
gek_Dmel         PLGI---------------DP-----------TRGIGTAYEGYVKVPKSG-VIKRGWIRQ
MRCKb_Mmus       PLGV---------------DV-----------QRGIGTAYKGYVKVPKPT-GVKKGWQRA
MRCKa_Mmus       PLGI---------------DP-----------QKGVGTAYEGHVRIPKPA-GVKKGWQRA
DMPK2_Mmus       ALGV---------------HP-----------ETGTGTAYEGFLSVPRPS-GVRRGWQRV
DMPK1_Mmus       PGL----------------SE---------------------------------------
K08B12.5_Cele    PLGM---------------IR---------------------------------------
DMPK2_Hsap       ALGV---------------HP-----------ETGTGTAYEGFLSVPRPS-GVRRGWQRV
DMPK1_Hsap       PGL----------------SE---------------------------------------
MRCK_Spur        PQGI---------------DP-----------TRGIGTAYEGVLRIPKPG-GVRKGWMKQ
CC1G_07309_Ccin  PGSAMSFISTSRRSGTPTVTMSTFSSRLRSASGSNFNISGMGMLGVPSPSLGPGGPWGRP
AqueK005_Aque    PSGI---------------DI-----------HHGVGTACEGWIQVPKPG-GVKKGWTRA
                 .

MRCKb_Hsap       YAVVCDCKLFLYDLPEGKSTQPGVIASQVLDLRDDEFSVSSVLASDVIHATRRDIPCIFR
MRCKa_Hsap       LAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFR
gek_Dmel         FVVVCDFKLFLYDISPDRCALPSVSVSQVLDMRDPEFSVGSVRESDVIHAAKKDVPCIFK
MRCKb_Mmus       YAVVCDCKLFLYDLPEGKSTQPGVVASQVLDLRDEEFAVSSVLASDVIHATRRDIPCIFR
MRCKa_Mmus       LAVVCDFKLFLYDIAEGKASQPTSVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFR
DMPK2_Mmus       YAALSDSRLLLFDAPDPRGSLASGVLLQALDLRDPQFSATPVLAPDVIHAQSKDLPRIFR
DMPK1_Mmus       ------------A------------------------------------------R----
K08B12.5_Cele    ------------HAEQNKMQDVKNEIRLVLDMRDPDFTVCGVSEADVIHAQKGDIPKIFR
DMPK2_Hsap       FAALSDSRLLLFDAPDLRLSPPSGALLQVLDLRDPQFSATPVLASDVIHAQSRDLPRIFR
DMPK1_Hsap       ------------A------------------------------------------L----
MRCK_Spur        FVVVCDFKLFLFDVLDGRASEPTNDISHILDMRDEEFSVSSVLASDVIHAPSKDVPCIFK
CC1G_07309_Ccin  WEHERD------------------------------------------------------
AqueK005_Aque    YAFVCDFKIFCHEPS-NDVHSPANGVFNIFDIRDINFRVSKVTRQDVIHAGEKLIPTIFK


MRCKb_Hsap       VTASLLGAPS------KTSSLLILTENENEKRKWVGILEGLQSILHKNRLRNQVVHVPLE
MRCKa_Hsap       VTASQLSASN------NKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKE
gek_Dmel         IKTALIDG-G------LSLNTLMLADNESEKSKWVIALGELHRILKRNSLPNTAIFKVNE
MRCKb_Mmus       VTASLLGSPS------KTSSLLILTENENEKRKWVGILEGLQAILHKNRLKSQVVHVAQE
MRCKa_Mmus       VTASQLSAPS------NKCSILMLADSENERSKWVGVLSELHKILKKNKFRDRSVYVPKE
DMPK2_Mmus       VTASQLTVPP------TTCTVLLLAENEGERERWLQVLGELQRLLLDARPRPRPVYTLKE
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    VTTTQILNSSSEYSSSSKFYTLFMAETEEEKRKWVVALSELKTLLRRSKLADRKAFLVKE
DMPK2_Hsap       VTTSQLAVPP------TTCTVLLLAESEGERERWLQVLGELQRLLLDARPRPRPVYTLKE
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        VSVSQLNPPG------LCAQLLLLADSEAEKRKWVDALNNLQRHLKHNQLPDRTVFRAQE
CC1G_07309_Ccin  ------------------------------------------------------------
AqueK005_Aque    ISCTHPTCSSV----GILSELLIRTDNENERDKWVATLDELQKAARQLATKKNPVISCHG


MRCKb_Hsap       AYD-SSLPLIKAILTAAIVDADRIAVGL-EEGLYVIEVTRDVIVRAAD--CKK-----VH
MRCKa_Hsap       AYD-STLPLIKTTQAAAIIDHERIALGN-EEGLFVVHVTKDEIIRVGD--NKK-----IH
gek_Dmel         ILD-NTLSLIRNALCSVIIYPNQILLGT-EDGLFYINLDQYEIARIGE--SKK-----IL
MRCKb_Mmus       AYD-SSLPLIKAVLAAAIVDGDRIAVGL-EEGLYVIELTRDVIVRAAD--CKK-----VY
MRCKa_Mmus       AYD-STLPLIKTTQAAAIIDHERIALGN-EEGLFVVHVTKDEIVRVGD--NKK-----IH
DMPK2_Mmus       AYD-NGLPLLPHALCAAVIDQERLALGT-EEGLFVIHLHSNDIFQVGD--CRR-----VQ
DMPK1_Mmus       -----CLLLFAAALAAA-------------------------------------------
K08B12.5_Cele    VFDVTTLPSIRVAQCCAIIDRSKIVIGFSDHGLYCIEISRQLLIPVGG--EKENKQRCVE
DMPK2_Hsap       AYD-NGLPLLPHTLCAAILDQDRLALGT-EEGLFVIHLRSNDIFQVGE--CRR-----VQ
DMPK1_Hsap       -----SLLLFAVVLSRA-------------------------------------------
MRCK_Spur        VFD-SSMPLVKVTHCADIVDASRFVIGT-EDGLYTVEISSGFIVRV-D--RKQ-----IH
CC1G_07309_Ccin  ------------------------------------------------------------
AqueK005_Aque    LYSSQQLQLLKSVQSAAIANNDRILLGA-EDGLYMFDVADEGLYQCGDKDLKR-----VI


MRCKb_Hsap       QIELAPREKIVILLCG--RNHHVHLYPWSSLDGAEGSF-DIKLPETKGCQLMATATLKRN
MRCKa_Hsap       QIELIPNDQLVAVISG--RNRHVRLFPMSALDGRETDF--YKLSETKGCQTVTSGKVRHG
gek_Dmel         QLWYIEEEQILVILCG--KQRNLRLLPIRALEASDVEW--IKVVESKNCISACTGIIRRF
MRCKb_Mmus       QIELAPKEKIAILLCG--RNHHVHLYPWSSFDGAEASNFDIKLPETKGCQLIATGTLRKS
MRCKa_Mmus       QIELIPSDQLVAVISG--RNRHVRLFPMSALDGRETDF--YKLAETKGCQTIAAGKVRHG
DMPK2_Mmus       RLAVSSAAGLLAVLCG--RGPSVRLFALDELESAEVAG--AKIPESRGCQALVAGRILQA
DMPK1_Mmus       --------------------------------------------ATLGCT----GL----
K08B12.5_Cele    TVEYDEAEQLLMMIVGPAKDRHVRIVPSAALDGRDLKW--IKVNDTKGCHLLAVGTNNPG
DMPK2_Hsap       QLTLSPSAGLLVVLCG--RGPSVRLFALAELENIEVAG--AKIPESRGCQVLAAGSILQA
DMPK1_Hsap       --------------------------------------------AALGCI----GL----
MRCK_Spur        QVRVLKDEQLVIVISG--RGRHLRLFPIACLDG-EATV--IKVEEPRGCTMFTTGIIRQG
CC1G_07309_Ccin  ------------------------------------------------------------
AqueK005_Aque    QLAVLQDEELVVILAG--RRPTLRLLPTSALDSGEMRNVVIDVTETKGAHLFCTGNL--G


MRCKb_Hsap       S--GTCLFVAVKR-----LILCYEIQRTK-PFHRKFNEIVAPGSVQCLAVLRD-RLCVGY
MRCKa_Hsap       A--LTCLCVAMKR-----QVLCYELFQSK-TRHRKFKEIQVPYNVQWMAIFSE-QLCVGF
gek_Dmel         PNIVYSFIIALKRPNNHTQIVVYEINRTR-TRHQKTCEFTIGYMAQHLQILSDMRLVVAH
MRCKb_Mmus       S--STCLFVAVKR-----LILCYEIQRTK-PFHRKFSELVAPGHVQWMAVFKD-RLCVGY
MRCKa_Mmus       A--LSCLCVAMKR-----QVLCYELFQSK-TRHRKFKEIQVPCNVQWMAIFSE-HLCVGF
DMPK2_Mmus       R--TPVLCVAVKR-----QVLCYQLGPGPGPWQRRIRELQAPAPVQSLGLLGD-RLCVGA
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    GR-AGFFAVAFKK-----SVTIFQIDRSE-KRHKKWKDLAMPGTPQSIAIFNG-RLYVGF
DMPK2_Hsap       R--TPVLCVAVKR-----QVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGD-RLCVGA
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        S--TTCMCVAMKR-----TVLIYEFNRNK-GRHKRIKEVTLPAPAQCMEVFGG-RLCAGY
CC1G_07309_Ccin  ------------------------------------------------------------
AqueK005_Aque    P--TQYICVAIKN-----KVLIYELSRTK-TRYERKKELVISGQVHSMSMVNE-KLCIGY


MRCKb_Hsap       PSGFCLLSIQG-DGQPL-------------NLVNPNDP-SLAFLSQQS-FDALCAV--EL
MRCKa_Hsap       QSGFLRYPLNG-EGNPY-------------SMLHSNDH-TLSFIAHQP-MDAICAV--EI
gek_Dmel         QSGFTAYFLRG-EATAM-------------SLVHPENQ-LCAFLNYSG-VDAVRVI--EI
MRCKb_Mmus       PSGFSLLSIQG-DGPPL-------------DLVNPTDP-SLAFLSQQS-FDALCAV--EL
MRCKa_Mmus       QSGFLRYPLNG-EGGPC-------------NMLHSNDH-TLSFISHQP-MDALCAV--EI
DMPK2_Mmus       AGTFALYPLLN-EAAPL-------------ALGTGLVAEELPASRGGL-GEALGAV--EL
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    SHSFRSWSLVGVDSSPVGSGDASGAVLQHISLVNMEDT-SLQFLNQQTSYEAKLIVNVPG
DMPK2_Hsap       AGGFALYPLLN-EAAPL-------------ALGAGLVPEELPPSRGGL-GEALGAV--EL
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        TSGFGLFSIQM-QGQHV------------EPLLNIDDP-SLRFLIEIP-TEALAAV--QI
CC1G_07309_Ccin  --------------------------------------R---------------------
AqueK005_Aque    LSGFSVFNVYL-DQPEI----------SQYXLVNNDDL-SLGFVRINE-LNAMCAV--EI


MRCKb_Hsap       ------ES-EEYLLCFSHMGLYVDPQGRRARAQELMWPAAPVACSCSPTHVTVYSEYGVD
MRCKa_Hsap       ------SS-KEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVD
gek_Dmel         LCPSGGNF-GEYLLVFQTLAIYVDLQGRKSRDREIMYPAFPTYITFCDGHLLVFSDTHLD
MRCKb_Mmus       ------KS-EEYLLCFSHMGLYVDPQGRRSRMQELMWPAAPVACSCSPTHVTVYSEYGVD
MRCKa_Mmus       ------SN-KEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVD
DMPK2_Mmus       ------SL-SELLLLFATAGVYVDSAGRKSRSHELLWPAAPTGWGYTAPYLTVFSENALD
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    ------SP-DEYLLVFNMIGLYVNEMGRRSRLPEVMFPTQAKYFAYHEPYLCVFSENEVD
DMPK2_Hsap       ------SL-SEFLLLFTTAGIYVDGAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSID
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        ------SE-REYLLCFSTLGVYVDYQGRRTREQELMWPSHPTEIAFNSPYLIVYSDISVD
CC1G_07309_Ccin  ----------DRDRESGGIGIGIGKVEERDREKERTFMAMPRKVSAPPV-----------
AqueK005_Aque    ------NNGQEYLLCFHLVGIYVTNEGRRSRKQELLWHSTPTSIVHRQPYLLVFCESNLE


MRCKb_Hsap       VFDVRTMEWVQTIGLRRIRPLNSEGTLNLLNC---EPPRLIYFKSKFS-GA--VLNVP-D
MRCKa_Hsap       IFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGL---ETIRLIYFKNKMAEGD--ELVVP-E
gek_Dmel         IFNTQTAEWVQSIGLKQSLPLNNLGNVVLSSVN--DTPLIVYLSNIHT-K--GLL----Q
MRCKb_Mmus       VFDVRTMEWVQTIGLRRIRPLNSDGSLNLLGC---EPPRLIYFKNKFS-GT--ILNVP-D
MRCKa_Mmus       IFDVNSMEWIQTLPLKKVRPLNTEGSLNLLGL---ETIRLIYFKNKMAEGD--ELVVP-E
DMPK2_Mmus       VFDVRRAEWVQTVPLKKVRPLNPEGSLFLYGT---EKVRLTYLRNPLAEKD--EFDIP-D
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    IFNVTLAEWVQTINLRSAKPLSGDGILSTCLCN--DSPIFVLLQNVLQDQD--SIEVPVN
DMPK2_Hsap       VFDVRRAEWVQTVPLKKVRPLNPEGSLFLYGT---EKVRLTYLRNQLAEKD--EFDIP-D
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        IYDIGIMEWVQTIPIKGTRQLSWDGSLNLSFVTDLHAPRLVYFHNRLAVSDHEKLNIQ-T
CC1G_07309_Ccin  IDDVQPVEEVE-------------------------------------------------
AqueK005_Aque    VYNVETSEWTQTISIKKLQSISPGGTIALCNSS--DSTCTVYIKSDS-DSSSN---IL-H


MRCKb_Hsap       TSDNSKKQMLRT-RSKRRFVFKVP--EEERLQQRREMLRDPEL--RSKMISNPTNFNHVA
MRCKa_Hsap       TSDNSRKQMVRNINNKRRYSFRVP--EEERMQQRREMLRDPEM--RNKLISNPTNFNHIA
gek_Dmel         YRDGNRKGL--P-SIKRRFSIREI--NKTIKSDR-----------RSKMISAPTNFNHIS
MRCKb_Mmus       TSDNSKKQMLRT-RSKRRFVFKVP--EEERLQQRREMLRDPEL--RSKMISNPTNFNHVA
MRCKa_Mmus       TSDNSRKQMVRNINNKRRYSFRVP--EEERMQQRREMLRDPEM--RNKLISNPTNFNHIA
DMPK2_Mmus       LTDNSRRQLFRT-KSKRRFFFRVS--DELRQQQRREMLKDPFV--RSKFISPPTNFNHLV
DMPK1_Mmus       ----------------------------------------------------------VA
K08B12.5_Cele    LASGSTD--GRK-VTRRKFTFRTIGKDDRSASERR----------SHIQISTPSDFMHIV
DMPK2_Hsap       LTDNSRRQLFRT-KSKRRFFFRVS--EEQQKQQRREMLKDPFV--RSKLISPPTNFNHLV
DMPK1_Hsap       ----------------------------------------------------------VA
MRCK_Spur        VVKSSKQ----Q-ANKRKFSFKSK--DEI-----R----------KNVIISAPSNFSHIT
CC1G_07309_Ccin  --------FPRNATTKPRIASAIP--PNKP------LLSNSSLRRTSVATSTPSVHEHCS
AqueK005_Aque    VTSVNRRGTVIT-KSKK-----------V-VKP------------ARPVISGPTEFAYVQ


MRCKb_Hsap       HMGPGDGMQVL--MDLPLSAVPPSQEERP---GP-------------------APTNLAR
MRCKa_Hsap       HMGPGDGIQIL--KDLPMNPRP--QESRTVFSGSV-SIPSITKSRPEPGRSMSASSGLSA
gek_Dmel         HMGPGDGIQNQRLLDLPTTLE--TADQAC---SP-------------------IIHSLSC
MRCKb_Mmus       HMGPGDGMQVL--MDLPLSAAPTVQEEKQ---GP-------------------TPAGLPR
MRCKa_Mmus       HMGPGDGIQIL--KDLPMNPRP--QESRTVFSGSV-SIPSITKSRPEPGRSMSASSGLSA
DMPK2_Mmus       HVGPTEGRPNT--RDGTRAQE---QKSR-GAR-----------------------SSGPQ
DMPK1_Mmus       YTGG--------------------------------------------------------
K08B12.5_Cele    HMGPAPVMELQ--QNFIDLQSNH-------------------------------------
DMPK2_Hsap       HVGPANGRPGA--RDKSPAPE---EKGR-VAR-----------------------GSGPQ
DMPK1_Hsap       HAGQ--------------------------------------------------------
MRCK_Spur        HMGPGDSLSKL--QDIPGAESKPVRIKS-MVGQPLPAQRSVTRQRPNTVINLS-------
CC1G_07309_Ccin  HSSGSRTHERRR----------------------------------------------AH
AqueK005_Aque    HFGPHPQLDVETM--QNAGE---VARLR---GA---SIPTLSMSQS-------TQSLSPR
                 : .

MRCKb_Hsap       QPPSRNKPYISWPSSGGSE----------------------------PS-----------
MRCKa_Hsap       RSSAQNGSALKREFSGGSY----------------------------SA-----------
gek_Dmel         IPQSRKSNFLE-------------------------------------------------
MRCKb_Mmus       QPPSRSKPYVSWPSSGGSE----------------------------PG-----------
MRCKa_Mmus       RSSAQNGSALKREFSGGSY----------------------------NT-----------
DMPK2_Mmus       RPHSFSE-AFRRPVSTGSDG-LPGET--------------------DPL-----------
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    ------------------------------------------------------------
DMPK2_Hsap       RPHSFSE-ALRRPASMGSEG-LGGDA--------------------DPM-----------
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        RDSDQNG-QLSLAPSGAAN----------------------------FE-----------
CC1G_07309_Ccin  ------------------------------------------------------------
AqueK005_Aque    KDHHHSQILSSHHYKAGSIEHLPAAYQSIEYKNIIVNIQFPPEYPANPLLLQIKSKVLPD


MRCKb_Hsap       ----------------------------------VTVPLRSMSD----------------
MRCKa_Hsap       ----------------------------------KRQPMPSPSEGSLSSGGMDQGSD---
gek_Dmel         ------------------------------------------------------------
MRCKb_Mmus       ----------------------------------VPVPLRSMSD----------------
MRCKa_Mmus       ----------------------------------KRQPMPSPSEGSLSSGGMDQGSD---
DMPK2_Mmus       ---------------------------------VKRKPWTSLSSESVSC---PQGSL---
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    ------------------------------------------------------------
DMPK2_Hsap       ----------------------------------KRKPWTSLSSESVSC---PQGSL---
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        ----------------------------------L----------SLTSRDGSQGSQ---
CC1G_07309_Ccin  ------------------------------------------------------------
AqueK005_Aque    KLIEKIETLCDQELKKLVGSKQVSTILLFLCDFIKNNPLIVCSEE-LQY---IKNTINRE


MRCKb_Hsap       ------------------------------------------------------------
MRCKa_Hsap       ------------------------------------------------------------
gek_Dmel         ------------------------------------------------------------
MRCKb_Mmus       ------------------------------------------------------------
MRCKa_Mmus       ------------------------------------------------------------
DMPK2_Mmus       ------------------------------------------------------------
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    ------------------------------------------------------------
DMPK2_Hsap       ------------------------------------------------------------
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        ------------------------------------------------------------
CC1G_07309_Ccin  ------------------------------------------------------------
AqueK005_Aque    GDELKIKQRTGVILYKAFQDQYFIDFKMTVPNEYPASHVQLEFKENNLPVNLYHIMKGQT


MRCKb_Hsap       ----------PDQDFDKEPDSDSTKHSTPSNS-------------------SNPSGPPSP
MRCKa_Hsap       ---------APARDFDGE-DSDSPRHSTASNS-------------------SNLSSPPSP
gek_Dmel         -----------------QVDANSDDY---GND-------------------NIISRTPSP
MRCKb_Mmus       ----------PDQDFDKEPDSDSTKHSTPSNS-------------------SNPSGPPSP
MRCKa_Mmus       ---------APARDYDGE-DSDSPRHSTASNS-------------------SNLSSPPSP
DMPK2_Mmus       ---------SPAASL-------------------------------------------IQ
DMPK1_Mmus       ------------------------------------------------------LTP---
K08B12.5_Cele    ---------------------------------------------------SHTSSD---
DMPK2_Hsap       ---------SPATSL-------------------------------------------MQ
DMPK1_Hsap       ------------------------------------------------------LTA---
MRCK_Spur        -------------GSP-DLSGYSPRHSLGEEA-------------------SSSGTPPTP
CC1G_07309_Ccin  ---------QPPRTYQYD-HEDTQHYSDEEDV-------------------DLLFQG---
AqueK005_Aque    VELLRQCVEPPIRRNPR-AGPFVPRPSLQFITNYLVVDCLRSITTDSCPVCNKRALPTDP


MRCKb_Hsap       N-----------------------------------------------------------
MRCKa_Hsap       A-----------------------------------------------------------
gek_Dmel         M-----------------------------------------------------------
MRCKb_Mmus       N-----------------------------------------------------------
MRCKa_Mmus       I-----------------------------------------------------------
DMPK2_Mmus       V-----------------------------------------------------------
DMPK1_Mmus       ------------------------------------------------------------
K08B12.5_Cele    ------------------------------------------------------------
DMPK2_Hsap       V-----------------------------------------------------------
DMPK1_Hsap       ------------------------------------------------------------
MRCK_Spur        ------------------------------------------------------------
CC1G_07309_Ccin  I-----------------------------------------------------------
AqueK005_Aque    KDIIIDEGHPQYVYRIYCGHLYHFQCLDSYMKTPPFTGGKKCVKCGQRVFHDKWNVPPRL


MRCKb_Hsap       -SPH---RS--QLPLE----------------------------GLEQPACDT
MRCKa_Hsap       -SPR---KT-KSLSLE----------------------------STDRGSWDP
gek_Dmel         -AS------------S----------------------------FMDGLSNND
MRCKb_Mmus       -SPH---RS--QLPME----------------------------GLDQPSCDA
MRCKa_Mmus       -SPQ---KT-KSLSLE----------------------------STDRGSWDP
DMPK2_Mmus       -SER---P--RSLPPD------------------------------PESESSP
DMPK1_Mmus       --------------VW----------------------------CFPGATFAP
K08B12.5_Cele    --------------KD----------------------------SLNRSVNND
DMPK2_Hsap       -SER---P--RSLPLS------------------------------PELESSP
DMPK1_Hsap       --------------VW----------------------------RRPGAARAP
MRCK_Spur        --------------HR----------------------------MSYAEQDQS
CC1G_07309_Ccin  -SKS---ET-DVGSLWDELEGRHERMMYDIRMLEERLELVSRTVGGGSGRIRR
AqueK005_Aque    AEERWAHQEARKREIA----------------------------EVAEFLGFD