IRAKb_e_Smoe MDRNNE------------------------------------------------------
IRAKb_b-2_Smoe MFKALK------------------------------------------------------
IRAKb_c-2_Smoe MLMSSTHCRF--------------------------------------------------
IRAKb_h_Smoe MLRKASSKLD--------------------------------------------------
IRAKb_b-1_Smoe MFKARR------------------------------------------------------
IRAKb_d_Smoe MAYLQ-------------------------------------------------------
IRAKb_g-1_Smoe SVRQ--------------------------------------------------------
IRAKb_j_Smoe MRRDESSLRM--------------------------------------------------
IRAKb_c-1_Smoe LSST--HCRF--------------------------------------------------
IRAKb_f_Smoe MDSSSKPMNGSAGGSPVGDERKMGDHEHEFRISIILLRSFLLVLVIISEALMVTDRETGS
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe ------------------------------------------------------------
IRAKb_b-2_Smoe ------------------------------------------------------------
IRAKb_c-2_Smoe --MK--------------------------------------------------------
IRAKb_h_Smoe --LA--------------------------------------------------------
IRAKb_b-1_Smoe ------------------------------------------------------------
IRAKb_d_Smoe ------------------------------------------------------------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe ------------------------------------------------------------
IRAKb_c-1_Smoe --MK--------------------------------------------------------
IRAKb_f_Smoe VPLPFFGLPRPVFVTKTAKYELVTGLKFYVDALGVVIGYTVLHLLFNIGLVATKGTVVDC
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe ------------------------------------------------------------
IRAKb_b-2_Smoe ------------------------------------------------------------
IRAKb_c-2_Smoe -------------------------KEVTYIN----------------------------
IRAKb_h_Smoe ------------------------------------------------------------
IRAKb_b-1_Smoe ------------------------------------------------------------
IRAKb_d_Smoe ------------------------------------------------------------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe ------------------------------------------------------------
IRAKb_c-1_Smoe -------------------------KEVTYIN----------------------------
IRAKb_f_Smoe KSVAWISFIADSMMGYLLLSSAAVATEIGYLAEEGAPAVLWRKVCNAFGYFCTVYAISVV
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe ------------------------------------------------------------
IRAKb_b-2_Smoe ------------------------------------------------------------
IRAKb_c-2_Smoe -----------------------------------------------------------E
IRAKb_h_Smoe ------------------------------------------------------------
IRAKb_b-1_Smoe ------------------------------------------------------------
IRAKb_d_Smoe ------------------------------------------------------------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe ------------------------------------------------------------
IRAKb_c-1_Smoe -----------------------------------------------------------E
IRAKb_f_Smoe ICFIAALVSFVVVGISAYHLFRLYGIQQQAAREKEKLSAEIYEAPRSFQRVEAMQPLLDE
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe ---------------------------------------------------------GNL
IRAKb_b-2_Smoe ---------------------------------------------------------GGT
IRAKb_c-2_Smoe LL-------------------------------------------ECNLAVMDKHGKGRV
IRAKb_h_Smoe ------------------------------RPPGGGA-----------------------
IRAKb_b-1_Smoe ---------------------------------------------------------GGT
IRAKb_d_Smoe ------------------------------------------------------------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe ---------------------------------------------------------GFL
IRAKb_c-1_Smoe LL-------------------------------------------ECNLAVMDKHGKGRV
IRAKb_f_Smoe ALDPNKELWLLRLPDLDLEELSNTSWRLKLEAADGNMGHLVCNGVKYSFQRHDIQGSSKY
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe LKV-----------------------------------SESVVLN--P------------
IRAKb_b-2_Smoe SN---------------------------N--------SVTVDPG--P------------
IRAKb_c-2_Smoe VKLVTPDKCDVDSSDLFELEVPL-GLTSMDSCTD---HKRKVNSS--P------------
IRAKb_h_Smoe ----ARHRLDFDRPKPFPMSFGLMG-----AAVGDKAKT--KKIAPS-------------
IRAKb_b-1_Smoe SN---------------------------N--------SVTVDPG--P------------
IRAKb_d_Smoe ------------------------------------------------------------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe ----------------------------------------S-------------------
IRAKb_c-1_Smoe VKLVTPDKCDVDSSDLFELEVPL-GLTSMDSCTD---HKRKVDSS--P------------
IRAKb_f_Smoe AYVPTQDKIEVRP---VPVEVSI-VR-SVEPTIAHPVAAENVDAAPNPAEGNFRVLRFLS
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe ------------------------------------------------------------
IRAKb_b-2_Smoe ------------------------------------------------------------
IRAKb_c-2_Smoe ------------------------------------------------------------
IRAKb_h_Smoe ------------------------------------------------------------
IRAKb_b-1_Smoe ------------------------------------------------------------
IRAKb_d_Smoe ------------------------------------------------------------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe ------------------------------------------------------------
IRAKb_c-1_Smoe ------------------------------------------------------------
IRAKb_f_Smoe RLGKMVMIRLYQYAGLTIGTYFALTYYIAHKDWVRELKYTREEQIEKARQLRQEKKRMRE
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe ------------------------------------------------------------
IRAKb_b-2_Smoe ------------------------------------------------------------
IRAKb_c-2_Smoe ------------------------------------------------------------
IRAKb_h_Smoe --SRSNLIARPESFR-----------QLAAEVIVVAIDGSKSITRHALEWALSN-VVQPG
IRAKb_b-1_Smoe ------------------------------------------------------------
IRAKb_d_Smoe ------------------------------------------------------------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe ------------------------------------------------------------
IRAKb_c-1_Smoe ------------------------------------------------------------
IRAKb_f_Smoe EQLRTNPILREEQERSAEEWKESSDEESQREVVLVAVDASKKMTDYALNWALANVVVHPG
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe ----------------------------------SLQLSSDVSS-------D--------
IRAKb_b-2_Smoe ----------------------------------SENAAVELDA-------VLPTELDET
IRAKb_c-2_Smoe ----------------------------------ENNNANQRSATSANAPAVSGEATDNT
IRAKb_h_Smoe DRIILLALLPSSSGK-----RWKFWKFAKFARDS--------ST-------KDKIRQEET
IRAKb_b-1_Smoe ----------------------------------SENAAVELDA-------VLPRELDET
IRAKb_d_Smoe -------------------------------------------A-------F--------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe -------------------------------------------L-------L-----R--
IRAKb_c-1_Smoe ----------------------------------ENNNANQRSAASANAPAVSGEATDST
IRAKb_f_Smoe DRIVFQAIAPASSTSNSSDSVWKSWGFPALGGECAAAAAASLKA-------TRKEELEEI
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe ------------------------------------------------------------
IRAKb_b-2_Smoe NTAI--------------------------------------------------------
IRAKb_c-2_Smoe TFASELVKCKLLLAILSIMF-LTV------------------------------------
IRAKb_h_Smoe RK-----SCQCMMEQLQSLFDAKKVQTTVKIYPSAEKGATTIEAKKLQATWVVLDRHLKK
IRAKb_b-1_Smoe NTAI--------------------------------------------------------
IRAKb_d_Smoe ------------------------------------------------------------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe ------------------------------------------------------------
IRAKb_c-1_Smoe TFASELVKCKLLLAILSIMF-LTV------------------------------------
IRAKb_f_Smoe RN-----KCSMVMEKLRKIHDLKKVHTTLEILQFARRGVIPSEAKRFRATWVVLDRNLKS
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe ------------------------------------------------------------
IRAKb_b-2_Smoe ------------------------------------------------------------
IRAKb_c-2_Smoe ------------------------------------------------------------
IRAKb_h_Smoe EEKRCSDNLQCNLVIVDRYNPKILRLNLKQSPEATPLEKAAVPPPLAK--QAETPASSPD
IRAKb_b-1_Smoe ------------------------------------------------------------
IRAKb_d_Smoe ------------------------------------------------------------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe ------------------------------------------------------------
IRAKb_c-1_Smoe ------------------------------------------------------------
IRAKb_f_Smoe EGKLCLQELNSNIVVVHRSNPKILRLNLKRR---------DL--PYDEEESID-SSSVLL
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe ------------------------------------------------------------
IRAKb_b-2_Smoe ------------------------------------------------------------
IRAKb_c-2_Smoe ------------------DYTANGQVSTIDSGFTAEESASLGS--FRCFLKLSPDKNSP-
IRAKb_h_Smoe VGTPFTSTSRGN-SSCSESSTSPFSGTEPGSYQTTT---------PESFGVTIEDVRRPE
IRAKb_b-1_Smoe ------------------------------------------------------------
IRAKb_d_Smoe ------------------------------------------------------------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe ---------------------------SRKSGFV-----------------LEGD-----
IRAKb_c-1_Smoe ------------------DYTANGQVSTTDSGFIAEESAALGSRSFRCFLKLSPDKNSP-
IRAKb_f_Smoe NGLSLSVMPKGFDQLYWESSTSSSEASSPDSRLVTAPKFELSV--LEELLKNETRRKGPS
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe ---------SPNEGSVSSHKA---------------------------------LAERQQ
IRAKb_b-2_Smoe ------------------------------------------------------------
IRAKb_c-2_Smoe QGSIEAVSDRPSSGTGPISVQPDRRSEML--ELLGGPNELETKLF------DSYVEESSM
IRAKb_h_Smoe YGASESDSDDPTVVPRRWRNSSRNLSTKDHSKNK------EYKEARQAEGTSTCVSLSDL
IRAKb_b-1_Smoe ------------------------------------------------------------
IRAKb_d_Smoe ------------------------------------------------------------
IRAKb_g-1_Smoe ------------------------------------------------------------
IRAKb_j_Smoe -----ESSSAR-------------------------------------------------
IRAKb_c-1_Smoe QGSIEAVSDRPSCGMVPISVQPDRRSEML--ELLGGPNELETKLF------DSYVEESSM
IRAKb_f_Smoe -PS-EVLN---STTSSPASHKPQVLNDFL--RMK------ESREYTEE--T---DT----
IRAKb_g-2_Smoe ------------------------------------------------------------
IRAKb_e_Smoe IIALELESKQQHGPETE-------------------TREVTHSDPAPPVCLICESQKR--
IRAKb_b-2_Smoe ----KLDKEKLTTDEAITED--------------TI-LFPKPGSSALPLCSVCKHKPRD-
IRAKb_c-2_Smoe LLGSKLHQEAGGNEEAFVKNVVSDLDRCFSVVENHEAKGASGNQGAAPLCHLCNNKSPR-
IRAKb_h_Smoe LTSCKLSSEL------DERNNRPNCEEATSIRRAVSLT-THSPLEPPPLCSICQHKAPV-
IRAKb_b-1_Smoe ----KLDKEKLTTDEAITED--------------TI-LFPKPGSSALPLCSICKHKPRD-
IRAKb_d_Smoe -------------------------------------TPVFSQQDFDKRCSGCYCKTRN-
IRAKb_g-1_Smoe ---------------------------------AVALPLKRSLAGSPPLCSICQHASPV-
IRAKb_j_Smoe --------------------------------SSGSVAPSTELEGAAYVCSACKTRSFRS
IRAKb_c-1_Smoe LLGSKLHQEAGGNEEAFLKDVVSDLDRCFSVVENHEAKGASGNQGAAPLCHLCNNKSPR-
IRAKb_f_Smoe -----------------QRNVSRPVDRVSSVRKQIHL-RKQSSPQPPPLCSICQHKTPV-
IRAKb_g-2_Smoe ---------------------------------AVALPLKRSLAGSPPLCSICQHASPV-
* *
IRAKb_e_Smoe -FRTTTNFTYAELEEATLNFSPGNFLAEGGYGPVYRGIL-KDGRYIAVKRNKDASTQGEK
IRAKb_b-2_Smoe FKRQTREFTYSELEEATDNFSHANFLAEGGFGFVYKGVL-KGGQHIAVKQHKLASTQGGR
IRAKb_c-2_Smoe FGTQPIMFSFSKIEEATNKFSKENLVAEGGFGFVYKGVL-SDGQLVAVKQHKLASRQGDR
IRAKb_h_Smoe FGRPPREFTFEELELATGGFSQANFLAEGGFGSVHRGVL-PEGQVVAVKQHKLASSQGDV
IRAKb_b-1_Smoe FKRQTREFTYSELEEATDNFSHANFLAEGGFGFVYKGVL-KGGQHIAVKQHKLASTQGGR
IRAKb_d_Smoe -AQEIREFKLAEIEEATHSFSQANFLSEGGFGNVFKGILLEQGLEVAVKRHKLKSTQGDK
IRAKb_g-1_Smoe FGRPPRRFSYSELEFATGGFCKANFLAEGGYGSVHRGVL-GDGIPVAVKQYKLASSQGDL
IRAKb_j_Smoe SGRPLKVFFSDELKAATNDFGFCNYMADAEGGHVFRGVL-EGGEVVAVRVISDASV----
IRAKb_c-1_Smoe FGTQPIVFSFSKIEEATNKFSKENLVAEGGFGFVYKGVL-SDGQLVAVKQHKLASRQGDR
IRAKb_f_Smoe FGKPPRKFTFAELQLATGGFSDVNFLAEGGYGSVYRGRL-PDGQAVAVKQHKLASTQGDK
IRAKb_g-2_Smoe FGRPPRRFSYSELEFATGGFCNANFLAEGGYGSVHRGVL-GDGIPVAVKQYKLASSQGDL
* ::: ** * * :::. * *.:* * * :**: . *
IRAKb_e_Smoe EFKAEVEALSGAQHRNLVTLLGFCIEG-GKRILVYEFVCNKCLDWHLSAANT--NVLPWS
IRAKb_b-2_Smoe EFCAEVKVLSGAQHRNLVTLLGFCVED-GKRMLVYEFVCNKSLDYHLFDKN---TVLPWC
IRAKb_c-2_Smoe EFKAEVEVLSSAQHRNLVTLIGYCTEG-GRRILVYEFVCNGSLNKHLSRKNP--KPLDWP
IRAKb_h_Smoe EFCSEVEVLSCAQHRNVVMLIGYCMED-SRRLLVYEFICNNSLDAHLYGKTM--DPLEWK
IRAKb_b-1_Smoe EFCAEVKVLSGAQHRNLVTLLGFCVEG-GKRMLVYEFVCNKSLDYHLFDKN---TVLPWC
IRAKb_d_Smoe EFFAEIKVLSHTNHDNVVSLVGYCTEN-GQRILVYEYVCNGTLAWHLSAKNS--TVLSWP
IRAKb_g-1_Smoe EFCSEVEVLSCAQHRNVVMLIGYCIER-KRRLLVYEFICNGSLDSHIYGVTK--PPLKWS
IRAKb_j_Smoe -FQSRKQLLGRIRSPNIVRLVGYCDEGDDRKFLVYDFICNGSLEWHLTVLTR--NAMGWS
IRAKb_c-1_Smoe EFKAEVEVLSSAQHRNLVTLIGYCTEG-GRRILVYEFVCNGSLNKHLSRKNP--KPLDWP
IRAKb_f_Smoe EFCAEVEVLSCAQQRNLVMLIGYCAED-KKRLLVYEFVCNGSLDSHLYGRRSKTVTLEWP
IRAKb_g-2_Smoe EFCSEVEVLSCAQHRNVVMLIGYCIER-KRRLLVYEFICNGSLDSHIYGVTK--PPLKWS
* :. : *. . *:* *:*:* * :::***:::** * *: : *
IRAKb_e_Smoe ARHAVAVGAARALRYLHEGCRTGSIVHRDVRPHNILLTHDYTPKVGDF------GLARWQ
IRAKb_b-2_Smoe ARQGIALGAARAMRYLHEECRVGTIIHRDLRPHNILLTHDYAPMVGDF------GLARWN
IRAKb_c-2_Smoe SRQNIALGAARGLRYLHEECRIGCIVHRDVRPNNILVTHDFTALVGDF------GLARWQ
IRAKb_h_Smoe YRQRVAIGAARGLRYLHEECRVGCIVHRDMRPNNILLTHDYEPMVGDF------GLARWQ
IRAKb_b-1_Smoe ARQGVALGAARAMRYLHEECRVGTIIHRDLRPHNILLTHDYAPMVGDF------GLARWH
IRAKb_d_Smoe ARHSIAVGIAKALRYLHHECTQGRVIHRDIRPHNILLRHDFTPVVGDF------GLAKWE
IRAKb_g-1_Smoe SRHKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILLTHDFEPMVGDF------GLARWQ
IRAKb_j_Smoe IRKSIAVGIAKGLLYLHSY----SIVHRNLRSRNVLLTHDYTPVVSKLCFFSKSSLCHWV
IRAKb_c-1_Smoe SRQNIALGAARGLRYLHEECRIGCIVHRDVRPNNILVTHDFTALVGDF------GLARWQ
IRAKb_f_Smoe ARQKIALGAARALRYLHEECRVGCIVHRDMRPNNILLTHDFEPM----------------
IRAKb_g-2_Smoe SRHKIAVGAARGLRYLHEECRVGCIVHRDMRPNNILLTHDFEPMVGDF------GLARWQ
*: :*:* *:.: *** ::**::*..*:*: **: .
IRAKb_e_Smoe SNDDSAAQTRLVGTLGYLAPEYISSGEVTTKTDVYSFGVVLLELITGRRAINLSLPAGET
IRAKb_b-2_Smoe TSSQPAVETKVVGTLGYLAPEYASSGQVTEKADVYSFGVILLEMVTGRRSLDISLPHAEQ
IRAKb_c-2_Smoe ASGDTAEQTRVIGTIGYVAPEYAETGHITEKADVYSFGLVLLEIITGRPAFDSYQQPGQQ
IRAKb_h_Smoe PDGELGVETRVIGTFGYLAPEYTQSGQITEKADVYSFGIVLLELVTGRKAIDISRPKGQQ
IRAKb_b-1_Smoe TSSQPAVETKVIGTLGYLAPEYASSGQVTEKADVYSFGVILLEMVTGRRSLDISLPHAEQ
IRAKb_d_Smoe NDS-AAPETTLVAATGYVAPEYGATGVATEKADVYSFGIVLLEIITGRRAIDLSC--EQT
IRAKb_g-1_Smoe PDGDLGVETRVIGTFGYLAPEYAQTGHITEKADVFSFGVVLLELVTGRKAIDISRPRGQQ
IRAKb_j_Smoe SFVFISDAIAHFHVDSYSAPEHFRGHAVDEKNDIFSYGVILLELITSRKAMEDS---SQR
IRAKb_c-1_Smoe ARGDTAEQTRVIGTIGYVAPEYAETGQITEKADVYSFGLVLLEIITGRPAFDSYQQPGQQ
IRAKb_f_Smoe ------------------------------------------------------------
IRAKb_g-2_Smoe PDGDLGVETRVIGTFGYLAPEYAQTGHITEKADVFSFGVVLLELVTGRKAIDISRPRGQQ
IRAKb_e_Smoe SLIEWARPMIETREAESLIDKRLGDK----FNMYELHCMIHAASFCLRAAPSERATMSQV
IRAKb_b-2_Smoe CLTEWARPKLDVRDADSLLDPRLVKDLLQESQLYEIQAMVHAAAFCLRREPSQRPRMSQV
IRAKb_c-2_Smoe HLPDWATPFLAARAAHELLDERIDESS---IDEYELINMVTAASLCIQKDPSNRPKMSQV
IRAKb_h_Smoe CLTEWARPLLRKRVYRELVDPKLCGE----FEKDEVTCMLHAAFLCISRDPNTRPRMSQV
IRAKb_b-1_Smoe CLTEWARPKLDVRDADSLLDPRLVKDLLQESQLYEIQAMVHAAAFCLRREPSQRPRMSQV
IRAKb_d_Smoe SLVEWARPKLEVRDAKSLLDPRLGTD----VDEYQIQCMIHAAAFCLQEDPSRRLRIKQV
IRAKb_g-1_Smoe CLTEWARPLLEEQSHHELIDPALVNE----LNQYEAYCTLFAASLCIQRDAHLRPRMSQV
IRAKb_j_Smoe LLTEWASPLLRDFDRQKLVDPELGCDD---NNTYELVTMMSIASLCLNEDPLERPSASKV
IRAKb_c-1_Smoe HLPDWATPFLAARAAHELLDERIDESS---VDEYELINMVTAASLCIQKDPSKRPKMTQV
IRAKb_f_Smoe -----ARPFLREQKYEKLIDQRLRGR----FCVNEVENMLLAATLCIDPDPLIRPRMSQV
IRAKb_g-2_Smoe CLTEWARPLLEEQAHHELIDPALVNE----LNQYEAYCTLFAASLCIQRDAHLRPRMSQV
* * : .*:* : : : * :*: . * .:*
IRAKb_e_Smoe CVCLCLTKNSTR---------SLSCIPDFEDSRRRV------------------------
IRAKb_b-2_Smoe DT-YEE------------------------------------------------------
IRAKb_c-2_Smoe CSSLAV------------------------------------------------------
IRAKb_h_Smoe LRILEGEMIIDPAPASSLSDEDIPSRPVSEPTRRSTSAISSRKNRYIPSSVGHYSSGAAK
IRAKb_b-1_Smoe DT-YEE------------------------------------------------------
IRAKb_d_Smoe SKNIK-------------------------------------------------------
IRAKb_g-1_Smoe SQVFS-------------------------------------------------------
IRAKb_j_Smoe NVRELECL-IA----------LLNIVPDF-------------------------------
IRAKb_c-1_Smoe CSSLAV------------------------------------------------------
IRAKb_f_Smoe LRLLEGDSLSDTSLSSS-SSGLLNGSPVIAAV----------------------------
IRAKb_g-2_Smoe SKVFF-------------------------------------------------------
IRAKb_e_Smoe -----------------------------IRSTCYCL
IRAKb_b-2_Smoe -----------------------------------KS
IRAKb_c-2_Smoe -----------------------------------TL
IRAKb_h_Smoe EDGALARPNSGNLTLEELKAAYRHKLGHRRLSLGDAL
IRAKb_b-1_Smoe -----------------------------------KS
IRAKb_d_Smoe -----------------------------------TR
IRAKb_g-1_Smoe ----------------------------------EEN
IRAKb_j_Smoe ------------------------------EPARRGL
IRAKb_c-1_Smoe -----------------------------------TL
IRAKb_f_Smoe -----------------------------GAAVLQAY
IRAKb_g-2_Smoe ----------------------------------EEN