LATS1_Hsap MKRSEKPEGYRQMRPKTFPAS-NYTVSSRQMLQEIRESL-----RNLSKPS---------
LATS2_Hsap M------------RPKTFPAT-TYSGNSRQRLQEIREGL-----KQPSKSSVQGL---PA
T20F10.1_Cele MR------------PAA-PGT-TPNGASSDIRHQRG-V-APIP---FG------------
wts_Dmel MHPAGEKRGG-------RPND-KYTA---EALESIKQDL-----TRF-------------
LATS_Spur MQQYHH------QQPSPIPYD-EESGAKVSQISRLYQQQQPKGPDSPDSSIRDGS---SY
AqueK010_Aque MSSRESKDRK-VRKPAVGSSSQSSTAGNEQVLQGIRVNL-----AASRKSVTPSPVRETA
AqueK011_Aque MVKLP---------PNSSPL-NFK------------------------------------
LATS2_Mmus M------------RPKTFPAT-TYSGNSRQRLQEIREGL-----KQPSKASTQGL---LV
LATS1_Mmus MKRGEKPEGYRQMRPKTFPAS-NYPGSSRQMLQEIRESL-----RNLSKPS---------
* .
LATS1_Hsap ----DAA-----------KAEHNMSKMSTEDPRQ------------VRNPPKFGTH----
LATS2_Hsap GPNSDTS----------LDAKVLGSKDATRQQQQ------------MRATPKFGPY----
T20F10.1_Cele --STNSA----------IDAH-------------------------HNSEIRVGRH----
wts_Dmel --------------------EVQNNHRNNQNYTP------------LRYTATNGRN----
LATS_Spur ASSTDSSSLSNGSGYRTVPAPHGFKRKSSYDDRGQPLLQSNAAGDALQHPSPYGQQTSRQ
AqueK010_Aque TP-SPVTL---------VESSSPGSSRVKSRPSP------------VESERQRHRH----
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus GPNSDTS----------LDAKVLGSKDAS-RQQQ------------MRATPKFGPY----
LATS1_Mmus ----DAS-----------KAEHNLNKMSTEDPRQ------------VRNPPKFGTH----
LATS1_Hsap -------------------------------------------HKALQEIRNSLLPFAN-
LATS2_Hsap -------------------------------------------QKALREIRYSLLPFAN-
T20F10.1_Cele -------------------------------------------RAKLDEIRESLKAYEH-
wts_Dmel -------------------------------------------DALTPDYHHAKQPMEP-
LATS_Spur QIHLGGGSDNTRSLSSISSNNSFSDGRSSSIQQQQQAAYPGRSYTSIMAAGDNLAPNSQG
AqueK010_Aque -------------------------------------------GEQMARIRDNLKPHHKS
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus -------------------------------------------QKALREIRYSLLPFAN-
LATS1_Mmus -------------------------------------------HKALQEIRNSLLPFAN-
LATS1_Hsap ET----------------NSSRS-TSEVNPQMLQDLQAAGFDE----------DMVIQ--
LATS2_Hsap ES----------------GTSA--AAEVNRQMLQELVNAGCDQ----------EMAGR--
T20F10.1_Cele EAGLLSSHVALGSLATPSSSSVS-HSDITNDNA-E-------------------------
wts_Dmel PP----------------SASPA-PDVVIPP-PPA-------------------------
LATS_Spur MP-----------FA---GSVAPGGDSRLQTQWNTMNYSGYPAHSRDSSGQIHITAGRAP
AqueK010_Aque DP----------------GFNYP-PDAVDQDMLHELIMKGYDQ----------NSCIA--
AqueK011_Aque ---------------------------------------------------------A--
LATS2_Mmus ES----------------GTSA--AAEVNRQMLQELVNAGCDQ----------EMAGR--
LATS1_Mmus ET----------------SSSRS-PSEVNPQMFQDLQAAGFDE----------DMVIQ--
LATS1_Hsap --ALQKTN-NRSIEAAIEF--IS-----------KMSYQDPRREQMAAAAARPINA-SMK
LATS2_Hsap --ALKQTG-SRSIEAALEY--IS-----------KMGYLDPRNEQIVRV----IKQTSPG
T20F10.1_Cele --VMNFS---------------S-----------SSSN---------AA---ATT-TTVS
wts_Dmel --IVGQPG-AGSISVSGVG--VG-----------VVGVANGRVPK-------------MM
LATS_Spur PNNLQSTNHNRSVPSM-ERTKVANMLHIGNNGDIYQSYVNPKRDNSGYV-----------
AqueK010_Aque --ALIQCN-SHSVEAALDV--LM-----------SGKRSTPISTT-------------SS
AqueK011_Aque --YLLRMR-IRSIKIKVDL--VI-----------K-------------------------
LATS2_Mmus --ALKQTG-SRSIEAALEY--IS-----------KMGYLDPRNEQIVRV----IKQTSPG
LATS1_Mmus --ALQKTN-NRSIEAAVEF--IS-----------KMSYQDPRREQMSAAAARPINA-TMK
:
LATS1_Hsap PGNVQQSVNRKQSWKGSKESL--VPQ-RHGPP-LGES-VA-------YHSESPNSQTDVG
LATS2_Hsap KGLMPTPVTRRPSFEGTGDSF--ASYHQLSGT-PYEG-PSFGADGPTALEEMPRPYVDYL
T20F10.1_Cele SAAVSNSNSFRTEGGGHKMRITPMPQ-RHLMMDTGANETVFRSGKEMIRNGNPS------
wts_Dmel TALMPNKLIRKPSIERDTASS--HYL-RCSPA-LDSG-A------GSSRSDSPHSHHT-H
LATS_Spur ------------------SSL--TM-SRVPGP-ADSG-YN-------QITINPEDRTIKR
AqueK010_Aque TGL---------------SS----------------------------------------
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus KGLAPTPVTRRPSFEGTGEAL--PSYHQLGGA-NYEG-PA-------ALEEMPRQYLDFL
LATS1_Mmus PGNVQHSINRKQSWKGSKESL--VPQ-RHGPS-LGEN-VV-------YRSESPNSQADVG
LATS1_Hsap RP------LSGSGI-SA--FVQAHPSNGQRVNPPPP-P----------------------
LATS2_Hsap FP------GVGPHG-PG--HQHQHPPKGYGASVEAAGA-H-FPLQ-GAHYGRPHLLVPGE
T20F10.1_Cele ---TTISSTPSTTT-E--ESIRIHP-AGYRYDMPTP-AY---------------------
wts_Dmel QP------SS-R--------TVGNP-GGNGGFSPSP-S----------------------
LATS_Spur QTVITISTTSSTTYSTGKQFTVSD-PMSSHNPPPYP-QGRTYNVQAATAAAQGQSIP--Q
AqueK010_Aque --------------------IRE-T-SGYHPHPPPP-Q----------------------
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus FP------GAGAGT-HGA-QAHQHPPKGYSTAVEPS-A-H-FP---GTHYGRGHLLS--E
LATS1_Mmus RP------LSGSGI-AA--FAQAHPSNGQRVNPPPP-P----------------------
LATS1_Hsap ------------------------------------------------------------
LATS2_Hsap PLGYG--------------VQ---RS----------------------------------
T20F10.1_Cele ------------------------------------------------------------
wts_Dmel ------------------------------------------------------------
LATS_Spur SNGYDLGQRHGTMTNATYSVQSTQVSSQLAAQHNPQAGSNVTYNGQSPNMSNHLNVQHGS
AqueK010_Aque ------------------------------------------------------------
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus QPGYG--------------VQ---RS----------------------------------
LATS1_Mmus ------------------------------------------------------------
LATS1_Hsap ---------QVRSVTPPPP-PRG----QTPPPRGTTPPPPSWEPNSQ--TKRYSGNMEYV
LATS2_Hsap --------PSFQSKTPPET-GGY----ASLPTKGQGGPPG--------------------
T20F10.1_Cele ---------HMNNNAPQYS-PG-----------YSRPPPPAYDSSP--VNTRM-------
wts_Dmel ---------GFSEVAPPAPPPRN----PTACS-AATPPPPV-PPTSQAYVKRRSPALNNR
LATS_Spur TSKEQHRSSAHIMILPPDNQPNMYSQDMISAMISKTQPPPSYEFSTQ--HRQTPNSIQTQ
AqueK010_Aque ---------Y-QTSLDN-------------------------------------------
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus --------SSFQNKTPPDA---Y----S-SMAKAQGGPPA--------------------
LATS1_Mmus ---------QVRSVTPPPP-PRG----QTPPPRGTTPPPPSWEPSSQ--TKRYSGNMEYV
LATS1_Hsap ISRISPVPPGAWQEGYPPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGR
LATS2_Hsap ----------AGL-AFPPPAAGLYVP-HPHHK----------------------------
T20F10.1_Cele ----TPVAT---------------------------------------------------
wts_Dmel PPAI---AP-PTQRGNSPVITQNGLKNPQQQLTQQLKSLN--------------------
LATS_Spur AGHI---GG-QQQR----------------------------------------------
AqueK010_Aque -----------------------SDLLPNHFETTSTSSLP--------------------
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus -----------SL-TFPA-HAGLYTA-S-HHK----------------------------
LATS1_Mmus ISRISPVPPGAWQEGYPPPPLTTSPMNPPSQAQRAISSVPVGRQPIIMQSTSKFNFTPGR
LATS1_Hsap PGMQNGTGQTDFMIHQNVVPAGT--VNRQPPP-PYPLTAANGQSPSALQTGGSAAPSSYT
LATS2_Hsap -------------------------QA--GPA-A-----------HQLHVLGSRS-QVFA
T20F10.1_Cele ---------DNYRTHLH-MKVHP--VVKAPPPNPTMLNHNKNMAP---------PPPPPA
wts_Dmel -----------------LYPGGGSGAVVEPPP-PYLIQGGAGG---------AAPPPP--
LATS_Spur --------------------------------------------------GGT---PTMT
AqueK010_Aque --------------GQ-SFTKHS--VTMDPYP-PTLITRD--------------------
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus -------------------------PAATPPG-A-----------HPLHVLGTRG-PTFT
LATS1_Mmus PGVQNGGGQSDFIVHQN-VPTGS--VTRQPPP-PYPLTPANGQSPSALQTGASAAPPSFA
LATS1_Hsap NGSIPQSMMVPNRNSHNME------------LYNISVPGLQTNWPQSSS--------A--
LATS2_Hsap SDSPPQSLLTPSRNSLNVD------------LYELGSTSVQ-QWPAATL--------A--
T20F10.1_Cele KSTISIETMSEERKADNIQR-----------LYHTSMDK------KTA-S-------S--
wts_Dmel -------------------------------------PPSYTASMQSRQ--------S--
LATS_Spur QQQFNTARLTPQ-NSQNPSNSSTVFKPIPSQMGGGNVVQIQTQLPQHHQPQPAVVTISRI
AqueK010_Aque -------------------------------------------L----------------
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus GESSAQAVLAPSRNSLNAD------------LYELGSTV---PWSAAPL--------A--
LATS1_Mmus NGNVPQSMMVPNRNSHNME------------LYNINVPGLQTAWPQSSS--------A--
LATS1_Hsap -PAQSSPSSGHEIP-----TWQPNI--PVRSNSFN-----NP--LGNRASHSANSQPSAT
LATS2_Hsap -RRDSLQKPGLEAPPRAHVAFRPDCPVPSRTNSFN-----SHQPRPGPPGKAEPSLPAPN
T20F10.1_Cele -VVSINVASPHTTK-----VNVGDSP--LPSKSF-------I--IGPRYTADVDRKNFVN
wts_Dmel -PTQSQQSDYRKSP------------------------------SSGIYSATSAGSPSPI
LATS_Spur DPNNDLTGGSKPPP-----PYRPAA--PVQSVEMKTKDLHLKVPVPVPAAVSSTALPGPG
AqueK010_Aque -------SPIH-----------------------------------SSPDH---------
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus -RRDSLQKQGLEA-SRPHVAFRA---GPSRTNSFN-----NPQP--------EPSLPAPN
LATS1_Mmus -PAQSSPSGGHEIP-----TWQPNI--PVRSNSFN-----NP--LGSRASHSANSQPSAT
LATS1_Hsap TV---------------TAITP-APIQQPVKSMRVLKPELQTALAPTHPSWIPQP---IQ
LATS2_Hsap TV---------------TAVTA-AHILHPVKSVRVLRPEPQTAVGPSHPAWVPAP---AP
T20F10.1_Cele YK---------------DE----------------LRPDP--------------------
wts_Dmel TVSLPPAPLAKPQPRVYQARSQQPIIMQSVKSTQVQKPVLQTAVAPQSPSSASASNSPVH
LATS_Spur -------------------YSS-PPILQSVRSTTVAKPVLQKAHGPDQPPPARGS-SPDT
AqueK010_Aque ------SPHGTPPP-----------------------------------------ESKRH
AqueK011_Aque -----------------------------------------KVVGVASPD----------
LATS2_Mmus TV---------------TAVTA-AHILHPVKSVRVLRPEPQTAVGPSHPAWVAAP---TA
LATS1_Mmus TV---------------TAITP-APIQQPVKSMRVLKPELQTALAPTHPSWMPQP---VQ
LATS1_Hsap TV-QPSPFPE------------------------GTASNVTVMPPVAE------------
LATS2_Hsap AP-APAPAPAAEGLDAKEEHALA----------LGGAGAFPLDVEY-G------------
T20F10.1_Cele -----RLIPSTSDANHEDFRPIL---------------FKPRNLEI-T------------
wts_Dmel VLAAPPSYPQKSAAVVQQQQQAAAAAHQQQHQHQQSKPPTPTTPPLVGLNSKPNCLEPPS
LATS_Spur VS-T-------QSTSTQS---------------SSTRSESP-------------------
AqueK010_Aque VHVSPP--------------------------------PD-VQPR---------TYSPFS
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus PA--T------ESLETKE----------------GSAGPHPLDVDY-G------------
LATS1_Mmus TV-QPTPFSE------------------------GTASSVPVIPPVAE------------
LATS1_Hsap ------------------------------------------------------------
LATS2_Hsap ------------------------------------------------------------
T20F10.1_Cele ------------------------------------------------------------
wts_Dmel YAKSMQAKAATVVQQQQQQQQQQQQVQQQQVQQQQQQQQQQLQALRVLQAQAQRERDQRE
LATS_Spur ------------------------------------------------------------
AqueK010_Aque AP----------------------------------------------------------
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus ------------------------------------------------------------
LATS1_Mmus ------------------------------------------------------------
LATS1_Hsap ----------------APNY-QGPPPP-YPKHLLHQNPSVPPYES-----ISKPSKEDQP
LATS2_Hsap ----------------GPDR-RCPPPP-YPKHLLLRSKSEQY--D-----LDSLCAGMEQ
T20F10.1_Cele ----------------MKSR-AQPPPPQYNQ------PSEPPPKR-----V---------
wts_Dmel RDQRERERDQQKLANGNPGRQMLPPPP-YQSNNNNNSEIKPPSCNNNNIQISNSNLATTP
LATS_Spur -------------------------LV-RPPSLISEI-----------------------
AqueK010_Aque -----------------FSRQMQTPPV-YDRNARLPHG-------------------YSP
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus ----------------GSER-RCPPPP-YPKHLLLPSKSEQYSVD-----LDSLCTSVQQ
LATS1_Mmus ----------------APSY-QGPPPP-YPKHLLHQNPSVPPYES-----VSKPCKDEQP
LATS1_Hsap S----------------LPKEDESEKSYENVDSGDKEKKQITTSPITVRKN---KKDEER
LATS2_Hsap SL----------RAGPNEPEGGDKSRKSAKGDKGGKDKKQIQTSPVPVRKN---SRDEEK
T20F10.1_Cele ------------------------------------------SSPID-RTL---LEPYIK
wts_Dmel PIPPAKYNNNSSNTGANSSGGSNGST-GTTASSSTSCKKIKHASPIPERKKISKEKEEER
LATS_Spur --------------------SDVGDLESASSDSQPLEKSRI-ESPVPERRNK--GRHKER
AqueK010_Aque IIRPAS----------------------ELS---------------------DS-GIEEE
AqueK011_Aque ------------------------------------------------------------
LATS2_Mmus SL----------RGGTE-QDRSDKSHKGAKGDKAGRDKKQIQTSPVPVRKN---SRDEEK
LATS1_Mmus S----------------LPKEDDSEKSADSGDSGDKEKKQITTSPITVRKN---KKDEER
LATS1_Hsap RESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLC
LATS2_Hsap RESRIKSYSPYAFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILY
T20F10.1_Cele NTRRVQPCKPNMLRFYMEQHVERLLQQYKEREKRMKQLEKEMVSAQLPDIMRNKMLGLLQ
wts_Dmel KEFRIRQYSPQAFKFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLN
LATS_Spur YEPRVKTYNPQAYKFYMEQHVENILKSHRQRITRRMQLEQEMQRVDLTSGDRDQMRRMLF
AqueK010_Aque TAPQRNPVPPEAFKFYMEQHIENVLKAYQQRQQRRMKLEVEMGKRGLDEATCEQMRKLLA
AqueK011_Aque -------------------HTPRLPYVYLSIPFKWKKLEQSMSELELADEEREERRKQHA
LATS2_Mmus RESRIKSYSPYAFKFFMEQHVENVIKTYQQKVSRRLQLEQEMAKAGLCEAEQEQMRKILY
LATS1_Mmus RESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLC
* .: : . : :** .* * . :
LATS1_Hsap QKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDT-KALYATKTLRKKDVLLRN
LATS2_Hsap QKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDT-HALYAMKTLRKKDVLNRN
T20F10.1_Cele QKESKYTRLRRQKMSKSHFTVISHIGVGAFGKVSLVRKNDT-RKVYAMKSLEKADVIMKQ
wts_Dmel QKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRN
LATS_Spur QKESNYLRLKRAKMNKSMFKKIKTLGIGAFGEVALARKVDT-NALYAVKKLRKLDVIQRN
AqueK010_Aque QKESNFLRMKRAKMHRDQFDIVKPIGVGAFGVVSLVRKKDT-RRLYAMKSLRKADVVRRN
AqueK011_Aque QKETQFLRLRRSRLGKKDFKRLKIIGRGAFGEVVLVQKIDT-GHVYAMKVLRKSDMVEKE
LATS2_Mmus QKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKLDT-HALYAMKTLRKKDVLNRN
LATS1_Mmus QKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDT-KALYATKTLRKKDVLLRN
***::: *::* :: :. * :. :* **** * *. * ** :** * *.* *:: ::
LATS1_Hsap QVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLA
LATS2_Hsap QVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLA
T20F10.1_Cele QAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDLA
wts_Dmel QVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELA
LATS_Spur QAGHVKAERDILAEADNEWVVKLYYSFQDKDNLYFVMDYIPGGDLMSLLIRLEIFEEDLA
AqueK010_Aque QVAHVKAERDILAEADNEWVVKLYYSFQDAECLYFVMEYIPGGDMMSLLIKLGTFPEHLT
AqueK011_Aque QIAHARAERDILVEADNPWVVKMYYSFQDAINLYFIMEFLPGGDMMTLLMKKDILSEDVT
LATS2_Mmus QVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLA
LATS1_Mmus QVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPENLA
* .*.:******.***. *:*::::**** ***:*:::****:*:**:: : * ::
LATS1_Hsap RFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQS-
LATS2_Hsap RFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQK-
T20F10.1_Cele RFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPE
wts_Dmel RFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQEN
LATS_Spur RFYIAELVLAIESVHKMDFIHRDIKPDNILVDRDGHIKLTDFGLCTGFRWTHDSKYYQK-
AqueK010_Aque LFYIAELVCAIESVHKMGFIHRDIKPDNILIEADGHIKLTDFGLCTGFRWTHDSKRYQPK
AqueK011_Aque RFYIAESILAVDSIHKMSFIHRDIKPDNLLLDSRGHIKLSDFGLCTGLKIAHRTEFYRD-
LATS2_Mmus RFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQK-
LATS1_Mmus RFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQS-
***** *:: :*::.*****:****:*:: *****:*******:: :* . *
LATS1_Hsap G--DHP----RQDSMDFSN-EWGDPSSCRCG-----------------DRLKPLERRAAR
LATS2_Hsap G--SHV----RQDSMEPSD-LWDDVSNCRCG-----------------DRLKTLEQRARK
T20F10.1_Cele N--DHH----RVDSFSLPP-EVAA-----ID-----------------KSVKVLNVR--Q
wts_Dmel G--NHS----RQDSMEPWE-EYSE---N--G-----------------PKPTVLERRRMR
LATS_Spur S--GHA----RQDSMEPFD-TM-DGEKCKCINHFAHKEKELDLSSLDKRPLKTLERRRKR
AqueK010_Aque GSSGHT----RQGSIEPDTSAWGDQ--C--T-----------------CPMKPLEIRRLK
AqueK011_Aque L--SNVDLSDPQDSRRFS-QT-------------------------------------WK
LATS2_Mmus G--NHM----RQDSMEPGD-LWDDVSNCRCG-----------------DRLKTLEQRAQK
LATS1_Mmus G--DHP----RQDSMDFSN-EWGDPSNCRCG-----------------DRLKPLERRAAR
.: .* :
LATS1_Hsap QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
LATS2_Hsap QHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQL
T20F10.1_Cele QTRRITAHSLVGTGNYMAPEVIAKTGHNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQH
wts_Dmel DHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQ
LATS_Spur QQERCKAHSLVGTPNYIAPEVLTRTGYTQLCDWWSVGVILYEMLVGQPPFHADSPAETQW
AqueK010_Aque EHHRCVAHSLVGTPNYIAPEILRRVGYTQLCDWWSVGVIMYEMLVGQPPFMASAPADTQL
AqueK011_Aque KTRRDRAFSTVGTPDYIAPEVFMQTGYTHLCDYWSLGVIMYEMLMGFPPFCSEKPQDTYR
LATS2_Mmus QHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQL
LATS1_Mmus QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM
. .* *.* *** :*:***:: : *:.: **:** ***::**:.* ** * *
LATS1_Hsap KVINWQTSLHI-PPQAKLSPEASDLIIKLCRGPEDRLGKNGAD------EIKAHPFFKT-
LATS2_Hsap KVINWENTLHI-PAQVKLSPEARDLITKLCCSADHRLGRNGAD------DLKAHPFFSA-
T20F10.1_Cele RIKNWRNFLDF-TYCGNLSKECLMMIQQLICDASSRLGSHGKDVAERTAQVKNHPWFRG-
wts_Dmel KVINWEKTLHI-PPQAELSREATDLIRRLCASADKRLGKS-VD------EVKSHDFFKG-
LATS_Spur KVINWKQCLHI-PSQAKLSRDASDFILRLCTGPEERLGKNGVL------DIKSHPFFQT-
AqueK010_Aque KIVNWPEYLRI-PHHAQLSTAARDLVLRFLSDPQDRIGRNGAD------EIKHHPFFTSR
AqueK011_Aque KIMNWRQHLIFSPELPTISKDAESLIRSLLCDSQHRLGQD-VE------EIKRQPFFRG-
LATS2_Mmus KVINWESTLHI-PTQVRLSAEARDLITKLCCAADCRLGRDGAD------DLKAHPFFNT-
LATS1_Mmus KVINWQTSLHI-PPQAKLSPEASDLIIKLCRGPEDRLGKNGAD------EIKAHPFFKT-
:: ** * : . :* . :: : .. *:* ::* : :*
LATS1_Hsap IDFSSDLRQQSAS--YIPKITHPTDTSNFDPVDPDKLWSDDNEEE-NVNDTLNG-WYKNG
LATS2_Hsap IDFSSDIRKQPAP--YVPTISHPMDTSNFDPVDEESPWNDASEGSTKAWDTLTS---PNN
T20F10.1_Cele IDWV-NLRKLRADYIYIPRVTHDEDTSNFETFQDNDRA--------------DKP--NVR
wts_Dmel IDFA-DMRKQKAP--YIPEIKHPTDTSNFDPVDPEKLRSNDSTMS-SGDD--V----DQN
LATS_Spur IDLDSNIRKMKAP--YIPTVRHPTDTSNFDPVSPNKLGSDSSTDS---WDSNPNEEENHR
AqueK010_Aque IDWDVGIRNYVAP--YKPKIMYEGDTSNFDPVPQSQVQ-KMYKQA-TPTE--V----MPQ
AqueK011_Aque TDWD-HIRDRPAS--IPVHVKHMADTSNFDDFEELEHQKDH-EES-------------ES
LATS2_Mmus IDFSRDIRKQPAP--YVPTISHPMDTSNFDPVDEESPWHEASGESAKAWDTLAS---PSS
LATS1_Mmus IDFSSDLRQQSAS--YIPKITHPTDTSNFDPVDPDKLWSDGSEEE-NISDTLNG-WYKNG
* :*. * : : *****: . .
LATS1_Hsap KHPEHAFYEFTFRRFFDDNGY-PYNYPKPIEYEYINSQGSEQQSDEDDQNTGS-------
LATS2_Hsap KHPEHAFYEFTFRRFFDDNGY-PFRCPKPSGAEASQAESSD----LESSDLVD-------
T20F10.1_Cele GLHNPAFYEFTYRHFFDTDSV-GCPSLRPSRRRSLRPL----LE--NGTFNES-------
wts_Dmel DRTFHGFFEFTFRRFFDDKQP-PDM-----------------------------------
LATS_Spur QQTDHAFFEFTFRRFFDDNGH-PY--PMPIDIDSSPGPGEMERSEGDGAAAQS-------
AqueK010_Aque DHPEHAFYEFTFIRFAASDRASDAK--KPTIAPSSSSSSSSYHSQAQASSSGSSAHDRPQ
AqueK011_Aque DSKDWVFQNFTFKRFEG-------------------------------------------
LATS2_Mmus KHPEHAFYEFTFRRFFDDNGY-PFRCPKPSEPAESAD--------PGDADLEG-------
LATS1_Mmus KHPEHAFYEFTFRRFFDDNGY-PYNYPKPIEYEYIHSQGSEQQSDEDDQHTSS-------
* :**: :*
LATS1_Hsap -------------EIKNRDLVYV
LATS2_Hsap -------------QTEGCQPVYV
T20F10.1_Cele -------------VSEEDSSSHI
wts_Dmel --------------TDDQAPVYV
LATS_Spur -------------SLDMQDMVYV
AqueK010_Aque SSQREHKEMRKEKKRTTPQPVYV
AqueK011_Aque --------------LTQRGHVRL
LATS2_Mmus -------------AAEGCQPVYV
LATS1_Mmus -------------DGNNRDLVYV
: